NO961000L - Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike - Google Patents

Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike

Info

Publication number
NO961000L
NO961000L NO961000A NO961000A NO961000L NO 961000 L NO961000 L NO 961000L NO 961000 A NO961000 A NO 961000A NO 961000 A NO961000 A NO 961000A NO 961000 L NO961000 L NO 961000L
Authority
NO
Norway
Prior art keywords
preparation
piperidine derivatives
drug
preparation containing
methyl
Prior art date
Application number
NO961000A
Other languages
English (en)
Other versions
NO961000D0 (no
Inventor
Luc Even
Samir Jegham
Gerard Defosse
Michel Aletru
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO961000D0 publication Critical patent/NO961000D0/no
Publication of NO961000L publication Critical patent/NO961000L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Piperidinderivater med den generelle formel (I) (D hvor X representerer et oksygenatom eller en metylengruppe, R, representerer et klor- eller fluoratom eller en metyl, metoksy eller aminogruppe, og R2 og R3 representerer, uavhengig av hverandre, hydrogenatomer eller metylgrupper. Derivatene har terapeutisk anvendelse.
NO961000A 1995-03-13 1996-03-12 Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike NO961000L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9502863A FR2731708B1 (fr) 1995-03-13 1995-03-13 Derives de piperidine, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
NO961000D0 NO961000D0 (no) 1996-03-12
NO961000L true NO961000L (no) 1996-09-16

Family

ID=9476960

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961000A NO961000L (no) 1995-03-13 1996-03-12 Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike

Country Status (15)

Country Link
EP (1) EP0732334A1 (no)
JP (1) JPH08269058A (no)
KR (1) KR960034205A (no)
CN (1) CN1140174A (no)
AU (1) AU4800896A (no)
CA (1) CA2171579A1 (no)
CZ (1) CZ75496A3 (no)
FR (1) FR2731708B1 (no)
HU (1) HUP9600624A2 (no)
IL (1) IL117455A0 (no)
NO (1) NO961000L (no)
NZ (1) NZ286164A (no)
PL (1) PL313204A1 (no)
SK (1) SK34196A3 (no)
ZA (1) ZA961994B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2231887A1 (en) * 1995-09-18 1997-03-27 Glaxo Group Limited 5-ht3 receptor antagonists for dyskinesia
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
FR2801589A1 (fr) * 1999-11-25 2001-06-01 Sanofi Synthelabo Derives de 2-arylquinoleine, leur preparation et leur application en therapeutique
HRP20030081A2 (en) 2000-08-08 2005-02-28 Sanofi-Aventis Benzimidazole derivatives, preparation and therapeutic use thereof
FR2816619B1 (fr) * 2000-11-15 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816942B1 (fr) 2000-11-23 2003-05-09 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816941B1 (fr) * 2000-11-23 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
US9227985B2 (en) * 2013-03-15 2016-01-05 Incyte Corporation Tricyclic heterocycles as bet protein inhibitors
EP3019502B1 (en) * 2013-07-08 2017-05-17 Incyte Holdings Corporation Tricyclic heterocycles as bet protein inhibitors
US9399640B2 (en) 2013-11-26 2016-07-26 Incyte Corporation Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
WO2015081189A1 (en) 2013-11-26 2015-06-04 Incyte Corporation Bicyclic heterocycles as bet protein inhibitors
US9309246B2 (en) 2013-12-19 2016-04-12 Incyte Corporation Tricyclic heterocycles as BET protein inhibitors
MY180775A (en) 2014-04-23 2020-12-09 Incyte Corp 1h-pyrrolo[2,3-c]pyridin-7(6h)-ones and pyrazolo[3,4-c]pyridin-7(6h)-ones as inhibitors of bet proteins
US9527864B2 (en) 2014-09-15 2016-12-27 Incyte Corporation Tricyclic heterocycles as BET protein inhibitors
WO2017075377A1 (en) 2015-10-29 2017-05-04 Incyte Corporation Amorphous solid form of a bet protein inhibitor
KR102643344B1 (ko) 2016-06-20 2024-03-07 인사이트 코포레이션 Bet 저해제의 결정질 고체 형태
US11535633B2 (en) * 2018-06-28 2022-12-27 Jiangsu Hengrui Medicine Co., Ltd. Fused tricyclic heterocycle compounds and therapeutic uses thereof
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674855B1 (fr) * 1991-04-03 1994-01-14 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.
FR2696176B1 (fr) * 1992-09-28 1994-11-10 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
FR2710915B1 (fr) * 1993-10-04 1995-11-24 Synthelabo Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.

Also Published As

Publication number Publication date
PL313204A1 (en) 1996-09-16
NZ286164A (en) 1996-11-26
SK34196A3 (en) 1996-10-02
FR2731708A1 (fr) 1996-09-20
FR2731708B1 (fr) 1997-04-30
CZ75496A3 (en) 1996-10-16
JPH08269058A (ja) 1996-10-15
EP0732334A1 (fr) 1996-09-18
IL117455A0 (en) 1996-07-23
CN1140174A (zh) 1997-01-15
CA2171579A1 (en) 1996-09-14
NO961000D0 (no) 1996-03-12
HUP9600624A2 (en) 1997-01-28
KR960034205A (ko) 1996-10-22
HU9600624D0 (en) 1996-05-28
AU4800896A (en) 1996-09-26
ZA961994B (en) 1996-09-03

Similar Documents

Publication Publication Date Title
NO944911L (no) Ikke-peptid-takykininreseptorantagonister
HUP0101999A2 (hu) 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása
HUP0004434A2 (hu) Adamantánszármazékok és ezeket tartalmazó gyógyászati készítmények
NO996108L (no) 9-oksinerytromycinderivater
HUP0002347A2 (hu) Hidantoin-, oxazol- és pirrolszármazékok alkalmazása gyulladásos betegségek kezelésére alkalmazható gyógyszerkészítmények előállítására
CY2488B1 (en) New 4-(oxyalkoxyphenyl)-3-oxy-piperidines for trea.
MY119150A (en) Azetidine derivatives, their preparation and medicaments containing them
MX9701679A (es) Derivados de piperidina como antagonistas de la neuroquinina.
NO922851L (no) Trifluormetylbenzylfosfonater som er nyttig for behandling av osteporose
HUP0401886A2 (hu) Kemokin receptor aktivitás modulátorokként alkalmazható piperidinszármazékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
DE3576690D1 (de) Pyrimidopyrimidinderivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als anti-allergische mittel.
HUP9802762A2 (hu) Difenil-metilén-piperidin-származékok, e vegyületeket tartalmazó gyógyászati készítmények, eljárás előállításukra és alkalmazásuk
NO934485L (no) Fremgangsmaate for fremstilling av derivater av baccatin-III og 10 -des-acetyl-baccatin-III
NO974734D0 (no) Arylglycinamidderivater, fremgangsmåte for fremstilling av disse forbindelsene og farmasöytiske blandinger inneholdende slike forbindelser
NO964667L (no) Purin-6-on-derivater
FR2712591B1 (fr) Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
DE69229339D1 (de) Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung
DK0424244T3 (da) 3-aryl-oxazolidinon-derivater, fremgangsmåde til fremstilling deraf og terapeutisk anvendelse deraf
NO990463L (no) Azabicykliske karbamoyloksymutilinderivater for antibakteriell anvendelse
HUT56092A (en) Process for producing 2-amino-pyrimidine-4-carboxamide derivatives and pharmaceutical compositions containing them
DE68903680D1 (de) 6-phenyl-3-piperazinylalkyl-1h,3h-pyrimidindion-2,4-derivate, deren herstellung und verwendung als heilmittel.
ES2073258T3 (es) Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica.
GR920100570A (el) Παραγωγα 3(2η)-πυριδαζινονης και μεθοδος για την παρασκευη τους.
DK0558677T3 (da) Biologisk active aminer
HUP9904294A2 (hu) Topiramát származékok alkalmazása neuropátiás fájdalom kezelésére alkalmas gyógyszer előállítására