NO961540L - Fremgangsmåte for fremstilling av metandifosfonsyre-forbindelser - Google Patents

Fremgangsmåte for fremstilling av metandifosfonsyre-forbindelser

Info

Publication number
NO961540L
NO961540L NO961540A NO961540A NO961540L NO 961540 L NO961540 L NO 961540L NO 961540 A NO961540 A NO 961540A NO 961540 A NO961540 A NO 961540A NO 961540 L NO961540 L NO 961540L
Authority
NO
Norway
Prior art keywords
alkyl
branched
straight
acid compound
base
Prior art date
Application number
NO961540A
Other languages
English (en)
Other versions
NO961540D0 (no
Inventor
Norio Kawabe
Keijiro Takanishi
Hiromi Uchiro
Ryuichi Haruta
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of NO961540D0 publication Critical patent/NO961540D0/no
Publication of NO961540L publication Critical patent/NO961540L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3865—Polyphosphonic acids containing sulfur substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4025—Esters of poly(thio)phosphonic acids
    • C07F9/4043—Esters of poly(thio)phosphonic acids containing sulfur substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

En fremgangsmåte for fremstilling av en 1-alkyltio- metandifosfonsyre-forbindelse eller 1-aryltlometan- difosfonsyreforbindelse omfatter fjerning av et tiolat- biprodukt som et uoppløselig salt ved en kondensasjons- reaksjon som representeres ved følgende formel skjema: o )2 R2S-SR2 RoS (OR1! )2 (a) Base || (b ) Base & Q metalloksyd O II ,P(OR'1)2 O II P(OR1)2 (A) der R'! betyr en rett eller forgrenet C1_6alkylgruppe, R2 betyr en alkyl- eller arylgruppe, R! betyr et farma- søytisk godtagbart kation, et hydrogenatom eller en rett eller forgrenet C^^alkylgruppe. Denne fremgangsmåte forbedrer vesentlig det oppnådde utbyttet sammenlignet med konvensjonelle metoder og forenkler samtidig renseprosessen og finner derved, på grunn av sin effektivitet, utstrakt industriell anvendelse.
NO961540A 1994-08-24 1996-04-18 Fremgangsmåte for fremstilling av metandifosfonsyre-forbindelser NO961540L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19944394 1994-08-24
PCT/JP1995/001683 WO1996006100A1 (en) 1994-08-24 1995-08-24 Process for producing methanediphosphonic acid compound

Publications (2)

Publication Number Publication Date
NO961540D0 NO961540D0 (no) 1996-04-18
NO961540L true NO961540L (no) 1996-04-18

Family

ID=16407907

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961540A NO961540L (no) 1994-08-24 1996-04-18 Fremgangsmåte for fremstilling av metandifosfonsyre-forbindelser

Country Status (14)

Country Link
US (1) US5886206A (no)
EP (1) EP0725070B1 (no)
JP (1) JP3493663B2 (no)
KR (1) KR100369929B1 (no)
CN (1) CN1055476C (no)
AT (1) ATE235499T1 (no)
AU (1) AU699641B2 (no)
CA (1) CA2174435A1 (no)
DE (1) DE69530064T2 (no)
ES (1) ES2196075T3 (no)
FI (1) FI961749A0 (no)
NO (1) NO961540L (no)
TW (1) TW327173B (no)
WO (1) WO1996006100A1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030030075A (ko) * 2001-10-06 2003-04-18 조한주 원심력을 이용한 휴대용 산소 방울 콘택트 렌즈 세척기

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
CH675422A5 (no) * 1988-03-31 1990-09-28 Symphar Sa
JPH0377894A (ja) * 1989-08-18 1991-04-03 Toray Ind Inc メチレンジホスホン酸化合物
JP3341303B2 (ja) * 1991-07-11 2002-11-05 東レ株式会社 メチレンジホスホン酸誘導体、その製造方法およびその医薬用途
EP0603401B1 (en) * 1992-07-10 2001-04-11 Toray Industries, Inc. Methanediphosphonate derivative, production thereof, and pharmaceutical use thereof
WO1994019359A1 (en) * 1993-02-25 1994-09-01 Toray Industries, Inc. Process for producing methanediphosphonate compound

Also Published As

Publication number Publication date
TW327173B (en) 1998-02-21
AU3265095A (en) 1996-03-14
EP0725070A4 (en) 1997-10-22
JP3493663B2 (ja) 2004-02-03
WO1996006100A1 (en) 1996-02-29
DE69530064T2 (de) 2003-12-18
FI961749L (fi) 1996-04-23
EP0725070B1 (en) 2003-03-26
CN1055476C (zh) 2000-08-16
NO961540D0 (no) 1996-04-18
ES2196075T3 (es) 2003-12-16
FI961749A7 (fi) 1996-04-23
KR960705831A (ko) 1996-11-08
FI961749A0 (fi) 1996-04-23
ATE235499T1 (de) 2003-04-15
CA2174435A1 (en) 1996-02-29
US5886206A (en) 1999-03-23
KR100369929B1 (ko) 2003-04-08
EP0725070A1 (en) 1996-08-07
AU699641B2 (en) 1998-12-10
DE69530064D1 (de) 2003-04-30
CN1137276A (zh) 1996-12-04

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