NO964905L - Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen - Google Patents
Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsenInfo
- Publication number
- NO964905L NO964905L NO964905A NO964905A NO964905L NO 964905 L NO964905 L NO 964905L NO 964905 A NO964905 A NO 964905A NO 964905 A NO964905 A NO 964905A NO 964905 L NO964905 L NO 964905L
- Authority
- NO
- Norway
- Prior art keywords
- drug
- atoms
- alkyl
- diagnostic
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 2
- 229940079593 drug Drugs 0.000 title 2
- KKEYFWRCBNTPAC-UHFFFAOYSA-N benzene-dicarboxylic acid Natural products OC(=O)C1=CC=C(C(O)=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-N 0.000 title 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical class OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 230000006378 damage Effects 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 102000050381 Na+/H+ exchanger Human genes 0.000 abstract 1
- 108091006672 Sodium–hydrogen antiporter Proteins 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 230000003293 cardioprotective effect Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19543194A DE19543194A1 (de) | 1995-11-20 | 1995-11-20 | Substituierte Benzoldicarbonsäure-diguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE1996124064 DE19624064A1 (de) | 1996-06-17 | 1996-06-17 | Substituierte Benzoldicarbonsäure-diguanidide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO964905D0 NO964905D0 (no) | 1996-11-19 |
| NO964905L true NO964905L (no) | 1997-05-21 |
Family
ID=26020502
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964905A NO964905L (no) | 1995-11-20 | 1996-11-19 | Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen |
| NO964903A NO964903D0 (no) | 1995-11-20 | 1996-11-19 | Substituerte benzendikarboksylsyre-diguanidid, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som medikament inneholdende dem |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964903A NO964903D0 (no) | 1995-11-20 | 1996-11-19 | Substituerte benzendikarboksylsyre-diguanidid, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som medikament inneholdende dem |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0774458A1 (es) |
| JP (1) | JPH09169719A (es) |
| KR (1) | KR980002018A (es) |
| AR (1) | AR004331A1 (es) |
| AU (1) | AU703352B2 (es) |
| BR (1) | BR9605617A (es) |
| CA (1) | CA2190693A1 (es) |
| CZ (1) | CZ338296A3 (es) |
| HR (1) | HRP960547A2 (es) |
| HU (1) | HUP9603201A3 (es) |
| IL (1) | IL119637A0 (es) |
| MX (1) | MX9605674A (es) |
| NO (2) | NO964905L (es) |
| NZ (1) | NZ299772A (es) |
| PL (1) | PL316438A1 (es) |
| SK (1) | SK148796A3 (es) |
| TR (1) | TR199600916A2 (es) |
| TW (1) | TW353657B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19819548A1 (de) | 1998-04-30 | 1999-11-04 | Merck Patent Gmbh | Biphenylderivate |
| DE10044732A1 (de) * | 2000-09-09 | 2002-03-21 | Mahle Ventiltrieb Gmbh | Rollenstößel für einen Verbrennungsmotor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2089600T3 (es) * | 1992-02-15 | 1996-10-01 | Hoechst Ag | Benzoilguanidina sustituida en 3,5, con efecto antiarritmico y efecto inhibidor de la proliferacion de celulas. |
| IL109570A0 (en) | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| IL114670A0 (en) * | 1994-08-05 | 1995-11-27 | Fujisawa Pharmaceutical Co | Guanidine derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
-
1996
- 1996-10-08 PL PL96316438A patent/PL316438A1/xx unknown
- 1996-11-07 EP EP96117822A patent/EP0774458A1/de not_active Withdrawn
- 1996-11-18 TR TR96/00916A patent/TR199600916A2/xx unknown
- 1996-11-18 AU AU71804/96A patent/AU703352B2/en not_active Ceased
- 1996-11-18 IL IL11963796A patent/IL119637A0/xx unknown
- 1996-11-18 SK SK1487-96A patent/SK148796A3/sk unknown
- 1996-11-18 CZ CZ963382A patent/CZ338296A3/cs unknown
- 1996-11-18 AR ARP960105230A patent/AR004331A1/es unknown
- 1996-11-18 NZ NZ299772A patent/NZ299772A/xx unknown
- 1996-11-18 TW TW085114093A patent/TW353657B/zh active
- 1996-11-19 MX MX9605674A patent/MX9605674A/es unknown
- 1996-11-19 HU HU9603201A patent/HUP9603201A3/hu unknown
- 1996-11-19 HR HR19624064.6A patent/HRP960547A2/hr not_active Application Discontinuation
- 1996-11-19 KR KR1019960055375A patent/KR980002018A/ko not_active Withdrawn
- 1996-11-19 NO NO964905A patent/NO964905L/no unknown
- 1996-11-19 NO NO964903A patent/NO964903D0/no unknown
- 1996-11-19 BR BR9605617A patent/BR9605617A/pt unknown
- 1996-11-19 CA CA002190693A patent/CA2190693A1/en not_active Abandoned
- 1996-11-19 JP JP8307831A patent/JPH09169719A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HU9603201D0 (en) | 1997-01-28 |
| PL316438A1 (en) | 1997-05-26 |
| NO964905D0 (no) | 1996-11-19 |
| HUP9603201A3 (en) | 1997-11-28 |
| EP0774458A1 (de) | 1997-05-21 |
| AU703352B2 (en) | 1999-03-25 |
| NZ299772A (en) | 1998-12-23 |
| TW353657B (en) | 1999-03-01 |
| KR980002018A (ko) | 1998-03-30 |
| CA2190693A1 (en) | 1997-05-21 |
| TR199600916A2 (tr) | 1997-06-21 |
| AU7180496A (en) | 1997-05-29 |
| JPH09169719A (ja) | 1997-06-30 |
| IL119637A0 (en) | 1997-02-18 |
| AR004331A1 (es) | 1998-11-04 |
| BR9605617A (pt) | 1998-08-18 |
| NO964903D0 (no) | 1996-11-19 |
| CZ338296A3 (cs) | 1998-05-13 |
| HRP960547A2 (en) | 1998-02-28 |
| SK148796A3 (en) | 1997-10-08 |
| HUP9603201A2 (en) | 1997-05-28 |
| MX9605674A (es) | 1997-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9916732A (pt) | Derivados de ácido malÈnico, processo para a sua preparação, seu uso e composições farmacêuticas contendo-os (inibição da atividade do fator xa) | |
| NO934501L (no) | Karboksylsyrederivater, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling | |
| RU94044488A (ru) | Применение 2-фенил-3-ароилбензотиофенов для ингибирования симптомов пременструального синдрома/ дисфории, связанной с поздней лютеальной фазой | |
| RU94036758A (ru) | Применение 2-фенил-3-ароилбензотиофенов для лечения пери-менопаузного синдрома | |
| RU94036772A (ru) | Применение 2-фенил-3-ароилбензотиофенов для ингибирования эндометриоза | |
| NO930511D0 (no) | Orto-substituerte benzoylguanidiner, fremgangsmaater for fremstillling av dem, deres anvendelse som diagnostikum saavel som medikamenter som inneholder dem | |
| BR0108694A (pt) | Derivados de ácido malÈnico, processo para preparação dos mesmos, uso dos mesmos como inibidor de atividade do fator xa e composições farmacêuticas que contêm os mesmos | |
| ES2109545T3 (es) | Benzoilguanidina sustituida, procedimiento para su preparacion, su uso como medicamento o agente de diagnostico asi como el medicamento que la contiene. | |
| NO983435L (no) | Aspartylproteaseinhibitorer | |
| RU94037246A (ru) | Применение 2-фенил-3-ароилбензотиофенов для ингибирования разрушения хряща | |
| BR0206791A (pt) | Composto, formulação farmacêutica, uso de um composto, método de profilaxia ou tratamento de uma arritmia, e, processo para a preparação de um composto | |
| BR0016678A (pt) | Composto, formulação farmacêutica, uso de um composto, método para profilaxia ou tratamento de uma arritmia, e, processo para preparação de um composto | |
| CA2182062A1 (en) | Substituted cinnamic acid guanidides, a process for their preparation, their use as medicaments or diagnostic agents, and medicaments comprising them | |
| NO943210L (no) | Laktolderivater, deres fremstilling og anvendelse | |
| NO964905L (no) | Substituerte benzendikarboksylsyre-diguanidider, fremgangsmåte for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen | |
| HU9200335D0 (en) | Medical products with human interleukin-2 content | |
| NO944699L (no) | Aminosubstituerte benzensulfornylurinstoffer og -tiourinstoffer, fremgangsmåte for deres fremstilling og deres anvendelse som farmasöytika | |
| NO940844L (no) | Farmasöytisk aktive hydroksykarboksylsyrederivater | |
| MX9704094A (es) | Benzoil-guanidinas sustituidas en orto, procedimiento para su preparacion, su utilizacion como medicamento o agente de diagnostico, asi como medicamento que las contiene. | |
| NO305655B1 (no) | Antiarytmiske og kardiobeskyttende substituerte indenoylguanidiner, deres anvendelse for fremstilling av legemidler, samt legemiddel inneholdende disse | |
| HUP0102576A1 (hu) | Bifenil-szulfonil-cián-amidok, eljárás a vegyületek előállítására és gyógyszerként történő felhasználása | |
| MY117304A (en) | Ortho-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic, agent and a medicament comprising them. | |
| NO950665L (no) | Nye polyjoderte forbindelser, fremgangsmåte for deres fremstilling og kontrastmidler inneholdende disse | |
| NO972406L (no) | Bis-orto-substituerte benzoylguanidiner, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene | |
| MX9605538A (es) | Benzoil-guanidinas sustituidas con sulfonilamino, procedimiento para su preparacion, su empleo como medicamento o para diagnostico, asi como el medicamento que las contiene. |