NO965551L - Chirale forbindelser og opplösning derav - Google Patents

Chirale forbindelser og opplösning derav

Info

Publication number
NO965551L
NO965551L NO965551A NO965551A NO965551L NO 965551 L NO965551 L NO 965551L NO 965551 A NO965551 A NO 965551A NO 965551 A NO965551 A NO 965551A NO 965551 L NO965551 L NO 965551L
Authority
NO
Norway
Prior art keywords
dissolution
chiral compounds
glutarimides
rogletimide
enantiospecific
Prior art date
Application number
NO965551A
Other languages
English (en)
Other versions
NO965551D0 (no
Inventor
Raymond Mccague
Stephen John Clifford Taylor
Original Assignee
Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd
Publication of NO965551D0 publication Critical patent/NO965551D0/no
Publication of NO965551L publication Critical patent/NO965551L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Enantiomere glutarimider såsom aminoglutetimid og rogletimid blir fremstilt ved cyklisering av et tilsvarende esternitril som er et godt substrat for biotransformasjon med en enantiospesifikk esterase.
NO965551A 1994-05-27 1996-12-23 Chirale forbindelser og opplösning derav NO965551L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9410721A GB9410721D0 (en) 1994-05-27 1994-05-27 Chiral compounds and their resolution
PCT/GB1995/001228 WO1995032947A1 (en) 1994-05-27 1995-05-30 Chiral compounds and their resolution

Publications (2)

Publication Number Publication Date
NO965551D0 NO965551D0 (no) 1996-12-23
NO965551L true NO965551L (no) 1997-01-09

Family

ID=10755860

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965551A NO965551L (no) 1994-05-27 1996-12-23 Chirale forbindelser og opplösning derav

Country Status (9)

Country Link
EP (1) EP0763023A1 (no)
JP (1) JPH10500861A (no)
CN (1) CN1151731A (no)
AU (1) AU2572495A (no)
CA (1) CA2191363A1 (no)
FI (1) FI964709A7 (no)
GB (1) GB9410721D0 (no)
NO (1) NO965551L (no)
WO (1) WO1995032947A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000055122A1 (en) * 1999-03-16 2000-09-21 Eisai Co., Ltd. Nitrile derivatives
RU2152386C1 (ru) * 1999-05-27 2000-07-10 Российский Университет Дружбы Народов Способ получения 2,3,5,6-тетраоксо-4-нитропиридата аммония
US6884791B2 (en) 1999-07-06 2005-04-26 Methylgene, Inc. Inhibitors of β-lactamase
AU770599B2 (en) 1999-07-06 2004-02-26 Methylgene Inc. Sulfonamidomethyl phosphonate inhibitors of beta-lactamase
WO2006128590A1 (en) * 2005-05-31 2006-12-07 Dsm Ip Assets B.V. Hydrolases, nucleic acids encoding them and methods for making and using them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
DE3724520C2 (de) * 1986-07-31 1996-01-11 Madaus Ag Neue 3-Aryl-3-Cycloalkyl-piperidin-2,6-dion-Derivate
EP0599959A1 (en) * 1991-08-22 1994-06-08 Chiroscience Limited Chiral glutarate esters, their resolution and derived glutarimide compounds

Also Published As

Publication number Publication date
FI964709L (fi) 1996-11-26
WO1995032947A1 (en) 1995-12-07
FI964709A0 (fi) 1996-11-26
CN1151731A (zh) 1997-06-11
EP0763023A1 (en) 1997-03-19
NO965551D0 (no) 1996-12-23
JPH10500861A (ja) 1998-01-27
GB9410721D0 (en) 1994-07-13
FI964709A7 (fi) 1996-11-26
CA2191363A1 (en) 1995-12-07
AU2572495A (en) 1995-12-21

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