NO970325L - Fremgangsmåte for fremstilling av biologisk aktivt dimerisk protein - Google Patents

Fremgangsmåte for fremstilling av biologisk aktivt dimerisk protein

Info

Publication number: NO970325L
Authority: NO; Norway
Prior art keywords: biologically active; dimeric protein; producing biologically; active dimeric; protein
Prior art date: 1994-07-25

Application number

NO970325A

Other languages

English (en)

Other versions

NO316926B1 (no

NO970325D0 (no

Inventor

Nico Cerletti

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-25

Filing date

1997-01-24

Publication date

1997-03-06

1997-01-24 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1997-01-24 Publication of NO970325D0 publication Critical patent/NO970325D0/no

1997-03-06 Publication of NO970325L publication Critical patent/NO970325L/no

2004-06-28 Publication of NO316926B1 publication Critical patent/NO316926B1/no

Links

102000004169 proteins and genes Human genes 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
239000003102 growth factor Substances 0.000 abstract 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Cephalosporin Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

NO19970325A 1994-07-25 1997-01-24 Fremgangsmate for fremstilling av et dimerisk biologisk aktivt TGF-<beta>-protein NO316926B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP94810438		1994-07-25
PCT/EP1995/002718 WO1996003432A1 (en)	1994-07-25	1995-07-12	Novel process for the production of biologically active dimeric protein

Publications (3)

Publication Number	Publication Date
NO970325D0 NO970325D0 (no)	1997-01-24
NO970325L true NO970325L (no)	1997-03-06
NO316926B1 NO316926B1 (no)	2004-06-28

Family

ID=8218292

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19970325A NO316926B1 (no)	1994-07-25	1997-01-24	Fremgangsmate for fremstilling av et dimerisk biologisk aktivt TGF-<beta>-protein

Country Status (19)

Country	Link
US (1)	US6057430A (no)
EP (1)	EP0775159B1 (no)
JP (2)	JP3923516B2 (no)
KR (1)	KR100432839B1 (no)
AT (1)	ATE207933T1 (no)
AU (1)	AU690311B2 (no)
CA (1)	CA2194582C (no)
DE (1)	DE69523605T2 (no)
DK (1)	DK0775159T3 (no)
ES (1)	ES2166401T3 (no)
FI (1)	FI118083B (no)
HU (1)	HU222830B1 (no)
IL (1)	IL114701A (no)
NO (1)	NO316926B1 (no)
NZ (1)	NZ290373A (no)
PT (1)	PT775159E (no)
TW (1)	TW440566B (no)
WO (1)	WO1996003432A1 (no)
ZA (1)	ZA956138B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW517059B (en) *	1994-07-25	2003-01-11	Ciba Geigy Ag	New process for the production of biologically active protein
EP0943690B1 (en) *	1995-12-21	2006-11-29	Ajinomoto Co., Inc.	Method for refolding human activin a
DE19906096A1 (de)	1999-02-13	2000-08-17	Walter Sebald	Protein mit einem Heparin-bindenden Epitop
WO2001075095A1 (fr) *	2000-03-30	2001-10-11	Takeda Chemical Industries, Ltd.	Procede de production de proteine de recombinaison
AU2001246393A1 (en) *	2000-03-31	2001-10-08	Vaccine Chip Technology Aps	Immunostimulating properties of a fragment of tgf-beta
US7572474B2 (en)	2005-06-01	2009-08-11	Mead Johnson Nutrition Company	Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants
US8075934B2 (en) *	2008-10-24	2011-12-13	Mead Johnson Nutrition Company	Nutritional composition with improved digestibility
GB0514262D0 (en) *	2005-07-12	2005-08-17	Renovo Ltd	Promotion of epithelial regeneration
GB0604938D0 (en) *	2006-03-11	2006-04-19	Renovo Ltd	Proteins, nucleic acids and medicaments
GB0604964D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Protein folding
GB0604966D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Medicaments and proteins
GB0617816D0 (en) *	2006-09-11	2006-10-18	Renovo Ltd	Nucleic acids and methods of protein expression
US8986769B2 (en) *	2008-10-24	2015-03-24	Mead Johnson Nutrition Company	Methods for preserving endogenous TGF-β
US10919948B2 (en)	2016-12-30	2021-02-16	Biogend Therapeutics Co., Ltd.	Recombinant polypeptides, compositions, and methods thereof
EP3852820B1 (en) *	2018-09-17	2024-11-20	Board of Regents, The University of Texas System	Compositions and methods for treating bone injury

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4731440A (en) *	1985-02-22	1988-03-15	Monsanto Company	Method of somatotropin solubilization using dimethylsulfone and naturation
JPH0759598B2 (ja) *	1986-02-14	1995-06-28	藤沢薬品工業株式会社	ヒトインスリン様成長因子▲ｉ▼の製造法
EP0293785A3 (en) *	1987-05-29	1990-05-02	Oncogen Limited Partnership	Cloning and expression of simian transforming growth factor-ss1
US5061786A (en) *	1989-05-25	1991-10-29	Genentech, Inc.	Biologically active polypeptides based on transforming growth factor-β
GB8927546D0 (en) *	1989-12-06	1990-02-07	Ciba Geigy	Process for the production of biologically active tgf-beta
US5144006A (en) *	1991-06-13	1992-09-01	The Rockefeller University	Oxidative folding of peptide and protein substrates using hydrocarbon sulfoxides
AU2738392A (en) *	1991-11-11	1993-05-13	Ciba-Geigy Ag	Novel hybrid transforming growth factors

1995
- 1995-07-11 TW TW084107188A patent/TW440566B/zh not_active IP Right Cessation
- 1995-07-12 KR KR1019970700476A patent/KR100432839B1/ko not_active Expired - Fee Related
- 1995-07-12 JP JP50540096A patent/JP3923516B2/ja not_active Expired - Fee Related
- 1995-07-12 AU AU31095/95A patent/AU690311B2/en not_active Ceased
- 1995-07-12 AT AT95926857T patent/ATE207933T1/de not_active IP Right Cessation
- 1995-07-12 DE DE69523605T patent/DE69523605T2/de not_active Expired - Lifetime
- 1995-07-12 CA CA002194582A patent/CA2194582C/en not_active Expired - Fee Related
- 1995-07-12 DK DK95926857T patent/DK0775159T3/da active
- 1995-07-12 WO PCT/EP1995/002718 patent/WO1996003432A1/en not_active Ceased
- 1995-07-12 PT PT95926857T patent/PT775159E/pt unknown
- 1995-07-12 EP EP95926857A patent/EP0775159B1/en not_active Expired - Lifetime
- 1995-07-12 NZ NZ290373A patent/NZ290373A/en not_active IP Right Cessation
- 1995-07-12 HU HU9700210A patent/HU222830B1/hu not_active IP Right Cessation
- 1995-07-12 ES ES95926857T patent/ES2166401T3/es not_active Expired - Lifetime
- 1995-07-24 IL IL11470195A patent/IL114701A/xx not_active IP Right Cessation
- 1995-07-24 ZA ZA956138A patent/ZA956138B/xx unknown
1997
- 1997-01-20 FI FI970229A patent/FI118083B/fi active IP Right Grant
- 1997-01-24 NO NO19970325A patent/NO316926B1/no not_active IP Right Cessation
1998
- 1998-07-28 US US09/123,233 patent/US6057430A/en not_active Expired - Fee Related
2006
- 2006-11-09 JP JP2006304295A patent/JP2007031453A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
IL114701A0 (en)	1995-11-27
FI970229L (fi)	1997-01-20
DK0775159T3 (da)	2002-02-11
EP0775159B1 (en)	2001-10-31
TW440566B (en)	2001-06-16
JPH11505506A (ja)	1999-05-21
NO316926B1 (no)	2004-06-28
JP3923516B2 (ja)	2007-06-06
AU690311B2 (en)	1998-04-23
DE69523605T2 (de)	2002-07-11
CA2194582A1 (en)	1996-02-08
HUT76668A (en)	1997-10-28
FI118083B (fi)	2007-06-29
JP2007031453A (ja)	2007-02-08
WO1996003432A1 (en)	1996-02-08
NO970325D0 (no)	1997-01-24
US6057430A (en)	2000-05-02
IL114701A (en)	2005-11-20
ZA956138B (en)	1996-03-07
DE69523605D1 (de)	2001-12-06
ATE207933T1 (de)	2001-11-15
ES2166401T3 (es)	2002-04-16
KR100432839B1 (ko)	2004-08-30
EP0775159A1 (en)	1997-05-28
NZ290373A (en)	1998-04-27
PT775159E (pt)	2002-04-29
CA2194582C (en)	2008-09-02
AU3109595A (en)	1996-02-22
FI970229A0 (fi)	1997-01-20
HU222830B1 (hu)	2003-11-28

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Legal Events

Date	Code	Title	Description
2012-02-20	MM1K	Lapsed by not paying the annual fees