NO970341L - Imidazopyridin-azolidinoner - Google Patents

Imidazopyridin-azolidinoner

Info

Publication number
NO970341L
NO970341L NO970341A NO970341A NO970341L NO 970341 L NO970341 L NO 970341L NO 970341 A NO970341 A NO 970341A NO 970341 A NO970341 A NO 970341A NO 970341 L NO970341 L NO 970341L
Authority
NO
Norway
Prior art keywords
alkyl
alkoxy
halogen
represents hydrogen
azolidinoner
Prior art date
Application number
NO970341A
Other languages
English (en)
Other versions
NO307462B1 (no
NO970341D0 (no
Inventor
Wolfgang-Alexander Simon
Richard Riedel
Stefan Postius
Hans-Peter Kley
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of NO970341D0 publication Critical patent/NO970341D0/no
Publication of NO970341L publication Critical patent/NO970341L/no
Publication of NO307462B1 publication Critical patent/NO307462B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Fats And Perfumes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Polymerization Catalysts (AREA)
  • External Artificial Organs (AREA)

Abstract

Foreliggende oppfinnelse vedrører forbindelser med Formel (I), hvor RO betyr l-4C-alkyl, hydroksymetyl, halogen eller tiocyanat; RI betyr l-4C-alkyl; R2 betyr hydrogen, l-4C-alkyl, l-4C-alkoksy, halogen eller trifluormetyl; R3 betyr hydrogen eller l-4C-alkyl; R3' betyr hydrogen, l-4C-alkyl eller substituert l-4C-alkyl med en eller to like eller ulike substituenter valgt fra gruppen bestående av halogen, l-4C-alkoksy og 1-4C-alkoksy-l-4C-alkoksy; R4 betyr hydrogen, l-4C-alkyl, 1-4C-alkoksy, halogen eller trifluormetyl; R5 betyr hydrogen, l-4C-alkyl, l-4C-alkoksy eller halogen; A betyr O (oksygen) eller NH; og Y betyr 0 (oksygen) eller CH, og salter derav, samt terapeutisk anvendelse derav ved behandling av gastrointestinale sykdommer.
NO970341A 1994-07-28 1997-01-27 Imidazopyridin-azolidinoner NO307462B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH239194 1994-07-28
PCT/EP1995/002954 WO1996003405A1 (de) 1994-07-28 1995-07-26 Imidazopyridin-azolidinone

Publications (3)

Publication Number Publication Date
NO970341D0 NO970341D0 (no) 1997-01-27
NO970341L true NO970341L (no) 1997-02-10
NO307462B1 NO307462B1 (no) 2000-04-10

Family

ID=4232684

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970341A NO307462B1 (no) 1994-07-28 1997-01-27 Imidazopyridin-azolidinoner

Country Status (18)

Country Link
US (1) US6124313A (no)
EP (1) EP0773946B1 (no)
JP (1) JPH10505333A (no)
CN (1) CN1046726C (no)
AT (1) ATE215084T1 (no)
AU (1) AU700730B2 (no)
CA (1) CA2196078A1 (no)
CZ (1) CZ22697A3 (no)
DE (1) DE59510131D1 (no)
FI (1) FI970330A7 (no)
HU (1) HU220874B1 (no)
MX (1) MX9700624A (no)
NO (1) NO307462B1 (no)
NZ (1) NZ290820A (no)
PL (1) PL180278B1 (no)
RU (1) RU2138501C1 (no)
SK (1) SK197A3 (no)
WO (1) WO1996003405A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802794D0 (sv) 1998-08-21 1998-08-21 Astra Ab New compounds
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
DE10145457A1 (de) * 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US7105533B2 (en) * 2002-09-13 2006-09-12 Merck & Co., Inc. Fused heterobicyclo substituted phenyl metabotropic glutamate-5 modulators
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
KR20060099524A (ko) 2003-11-03 2006-09-19 아스트라제네카 아베 무증상 위식도 역류의 치료를 위한 이미다조[1,2-ａ]피리딘유도체
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
EP3412675A1 (en) * 2013-05-27 2018-12-12 Novartis AG Imidazopyrrolidinone derivatives and their use in the treatment of disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4409226A (en) * 1981-10-05 1983-10-11 Schering Corporation Imidazo[1,5-a]pyridines
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
EP0266890A1 (en) * 1986-10-07 1988-05-11 Yamanouchi Pharmaceutical Co. Ltd. Imidazopyridine derivatives, their production, and pharmaceutical compositions containing them
US4831041A (en) * 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound
AU686115B2 (en) * 1992-11-02 1998-02-05 Fujisawa Pharmaceutical Co., Ltd. Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
UA48122C2 (uk) * 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ

Also Published As

Publication number Publication date
PL318262A1 (en) 1997-05-26
ATE215084T1 (de) 2002-04-15
WO1996003405A1 (de) 1996-02-08
US6124313A (en) 2000-09-26
HU9700024D0 (en) 1997-02-28
FI970330A0 (fi) 1997-01-27
FI970330L (fi) 1997-01-27
NZ290820A (en) 1998-05-27
HUT77868A (hu) 1998-09-28
NO307462B1 (no) 2000-04-10
EP0773946A1 (de) 1997-05-21
EP0773946B1 (de) 2002-03-27
AU3166295A (en) 1996-02-22
MX9700624A (es) 1997-12-31
CZ22697A3 (en) 1997-07-16
AU700730B2 (en) 1999-01-14
RU2138501C1 (ru) 1999-09-27
CA2196078A1 (en) 1996-02-08
DE59510131D1 (de) 2002-05-02
HU220874B1 (en) 2002-06-29
JPH10505333A (ja) 1998-05-26
CN1046726C (zh) 1999-11-24
FI970330A7 (fi) 1997-01-27
SK197A3 (en) 1997-06-04
HK1002658A1 (en) 1998-09-11
CN1159806A (zh) 1997-09-17
PL180278B1 (pl) 2001-01-31
NO970341D0 (no) 1997-01-27

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JANUARY 2003