NO973545L - 10-deacetyl-14<beta>-hydroksybaccatin-III-derivater, fremgangsmåter ved fremstilling derav samt formuleringer inneholdende disse - Google Patents

10-deacetyl-14<beta>-hydroksybaccatin-III-derivater, fremgangsmåter ved fremstilling derav samt formuleringer inneholdende disse

Info

Publication number: NO973545L
Authority: NO; Norway
Prior art keywords: pct; derivatives; deacetyl; beta; sec
Prior art date: 1995-05-19

Application number

NO973545A

Other languages

English (en)

Other versions

NO316378B1 (no

NO973545D0 (no

Inventor

Ezio Bombardelli

Original Assignee

Indena Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-19

Filing date

1997-08-01

Publication date

1997-11-17

1997-08-01 Application filed by Indena Spa filed Critical Indena Spa

1997-08-01 Publication of NO973545D0 publication Critical patent/NO973545D0/no

1997-11-17 Publication of NO973545L publication Critical patent/NO973545L/no

2004-01-19 Publication of NO316378B1 publication Critical patent/NO316378B1/no

Links

125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
ICGQLNMKJVHCIR-UHFFFAOYSA-N 1,3,2-dioxazetidin-4-one Chemical compound O=C1ONO1 ICGQLNMKJVHCIR-UHFFFAOYSA-N 0.000 abstract 1
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical group NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
231100000433 cytotoxic Toxicity 0.000 abstract 1
230000001472 cytotoxic effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000032050 esterification Effects 0.000 abstract 1
238000005886 esterification reaction Methods 0.000 abstract 1
238000007306 functionalization reaction Methods 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO19973545A 1995-05-19 1997-08-01 10-deacetyl-14<beta>-hydroksybaccatin-III-derivater, formuleringer inneholdende disse, samt anvendelse derav ved fremstilling av anti-tumor-medikamenter NO316378B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITMI951022A IT1275435B (it)	1995-05-19	1995-05-19	Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
PCT/EP1996/001919 WO1996036622A1 (en)	1995-05-19	1996-05-08	10-deacetyl-14beta-hydroxybaccatine iii derivatives, a process for the preparation thereof and formulations containing them

Publications (3)

Publication Number	Publication Date
NO973545D0 NO973545D0 (no)	1997-08-01
NO973545L true NO973545L (no)	1997-11-17
NO316378B1 NO316378B1 (no)	2004-01-19

Family

ID=11371633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19973545A NO316378B1 (no)	1995-05-19	1997-08-01	10-deacetyl-14<beta>-hydroksybaccatin-III-derivater, formuleringer inneholdende disse, samt anvendelse derav ved fremstilling av anti-tumor-medikamenter

Country Status (17)

Country	Link
US (1)	US5917056A (no)
EP (1)	EP0862563B1 (no)
JP (1)	JP4112001B2 (no)
KR (1)	KR100399330B1 (no)
CN (1)	CN100335469C (no)
AT (1)	ATE195312T1 (no)
AU (1)	AU696366B2 (no)
CA (1)	CA2212357C (no)
DE (1)	DE69609723T2 (no)
DK (1)	DK0862563T3 (no)
ES (1)	ES2148766T3 (no)
GR (1)	GR3034321T3 (no)
IT (1)	IT1275435B (no)
NO (1)	NO316378B1 (no)
PT (1)	PT862563E (no)
RU (1)	RU2161615C2 (no)
WO (1)	WO1996036622A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1283633B1 (it) *	1996-05-10	1998-04-23	Indena Spa	Derivati tassanici loro sintesi e formulazioni che li contengono
US5917062A (en) *	1997-11-21	1999-06-29	Indena S.P.A	Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
US6858598B1 (en)	1998-12-23	2005-02-22	G. D. Searle & Co.	Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en)	1998-12-23	2004-12-21	G.D. Searle & Co.	Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
IT1318678B1 (it)	2000-08-10	2003-08-27	Indena Spa	Procedimento per la preparazione di derivati della baccatina iii.
IT1320107B1 (it)	2000-11-28	2003-11-18	Indena Spa	Procedimento per la preparazione di derivati tassanici.
ITMI20012186A1 (it) *	2001-10-19	2003-04-19	Indena Spa	Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012185A1 (it) *	2001-10-19	2003-04-19	Indena Spa	Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
KR101009467B1 (ko) *	2006-03-13	2011-01-19	주식회사 셀트리온화학연구소	도세탁셀의 합성에 유용한 탁산 유도체 및 그 제조방법
BRPI0818370A2 (pt) *	2007-10-09	2017-05-16	Segetis Inc	métodos de fabricar cetais e acetais
EP2080764B1 (en)	2008-01-18	2012-08-22	INDENA S.p.A.	Solid forms of ortataxel
US8252137B2 (en) *	2009-08-31	2012-08-28	Fleming Iii Joseph C	Building panel having plant-imitating structural core
CN104650109B (zh) *	2013-11-22	2019-01-01	江苏天士力帝益药业有限公司	紫杉烷类化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX9102128A (es) *	1990-11-23	1992-07-08	Rhone Poulenc Rorer Sa	Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
IT1254517B (it) *	1992-03-06	1995-09-25	Indena Spa	14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
US5475011A (en) *	1993-03-26	1995-12-12	The Research Foundation Of State University Of New York	Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

1995
- 1995-05-19 IT ITMI951022A patent/IT1275435B/it active IP Right Grant
1996
- 1996-05-05 US US08/875,770 patent/US5917056A/en not_active Expired - Lifetime
- 1996-05-08 KR KR1019970706156A patent/KR100399330B1/ko not_active Expired - Fee Related
- 1996-05-08 WO PCT/EP1996/001919 patent/WO1996036622A1/en not_active Ceased
- 1996-05-08 JP JP53451996A patent/JP4112001B2/ja not_active Expired - Fee Related
- 1996-05-08 CA CA002212357A patent/CA2212357C/en not_active Expired - Fee Related
- 1996-05-08 ES ES96916025T patent/ES2148766T3/es not_active Expired - Lifetime
- 1996-05-08 AU AU58939/96A patent/AU696366B2/en not_active Ceased
- 1996-05-08 DK DK96916025T patent/DK0862563T3/da active
- 1996-05-08 CN CNB961924209A patent/CN100335469C/zh not_active Expired - Fee Related
- 1996-05-08 RU RU97112894/04A patent/RU2161615C2/ru not_active IP Right Cessation
- 1996-05-08 AT AT96916025T patent/ATE195312T1/de active
- 1996-05-08 EP EP96916025A patent/EP0862563B1/en not_active Expired - Lifetime
- 1996-05-08 DE DE69609723T patent/DE69609723T2/de not_active Expired - Lifetime
- 1996-05-08 PT PT96916025T patent/PT862563E/pt unknown
1997
- 1997-08-01 NO NO19973545A patent/NO316378B1/no not_active IP Right Cessation
2000
- 2000-09-01 GR GR20000402008T patent/GR3034321T3/el unknown

Also Published As

Publication number	Publication date
PT862563E (pt)	2000-11-30
CA2212357A1 (en)	1996-11-21
CA2212357C (en)	2002-08-13
NO316378B1 (no)	2004-01-19
KR19980702749A (ko)	1998-08-05
DE69609723D1 (de)	2000-09-14
HK1011537A1 (en)	1999-07-16
RU2161615C2 (ru)	2001-01-10
AU696366B2 (en)	1998-09-10
ES2148766T3 (es)	2000-10-16
JPH11505232A (ja)	1999-05-18
NO973545D0 (no)	1997-08-01
IT1275435B (it)	1997-08-07
US5917056A (en)	1999-06-29
EP0862563B1 (en)	2000-08-09
JP4112001B2 (ja)	2008-07-02
CN100335469C (zh)	2007-09-05
GR3034321T3 (en)	2000-12-29
ITMI951022A1 (it)	1996-11-19
KR100399330B1 (ko)	2003-12-31
EP0862563A1 (en)	1998-09-09
ITMI951022A0 (it)	1995-05-19
AU5893996A (en)	1996-11-29
WO1996036622A1 (en)	1996-11-21
DE69609723T2 (de)	2000-12-14
ATE195312T1 (de)	2000-08-15
CN1177961A (zh)	1998-04-01
DK0862563T3 (da)	2000-10-30

Similar Documents

Publication	Publication Date	Title
NO973545D0 (no)	1997-08-01	10-deacetyl-14<beta>-hydroksybaccatin-III-derivater, fremgangsmåter ved fremstilling derav samt formuleringer inneholdende disse
ATE236894T1 (de)	2003-04-15	Pyranonverbindungenzur behandlung retroviraler infektionen
DZ2188A1 (fr)	2002-12-02	Dérivés de quinoxalinedone, procédés et intermédiaires pour leur préparation et compositions pharmaceutiques les contenant.
ATE74508T1 (de)	1992-04-15	Azithromycin und seine derivate als antiprotozoenmittel.
DZ2217A1 (fr)	2002-12-03	Dérivés d'imidazole substitués, procédé pour leur préparation et compositions les contenant.
RU1833372C (ru)	1993-08-07	Cпocoб пoлучehия пpoизboдhыx 2,4,5-зameщehhыx бehзoлa
NO974266D0 (no)	1997-09-16	10-deacetylbaccatin III- og 10-deacetyl-14<beta>-hydroksybaccatin III-derivater, fremgangsmåte ved deres fremstilling og farmasöytiske blandinger som inneholder dem
OA07985A (fr)	1987-01-31	Nouveaux dérivés céphem, procédé pour la préparation de ces nouveaux composés compositions pharmaceutiques contenant au moins un de ces composés et intermédiaires de synthèse pour leur préparation.
OA07390A (fr)	1984-11-30	Nouveaux dérivés de carbapenem, compositions pharmaceutiques les contenant, composés intermédiaires pour leur préparation, et leurs procédés de production.
FR2570278B1 (fr)	1987-02-13	Compositions et procede pour proteger les lymphocytes t contre l'agent etiologique des lymphadenopathies et du syndrome d'immunodepression acquise
HUT70446A (en)	1995-10-30	Pyridine derivatives, process for producing them and pharmaceutical compositions comprising them
OA08165A (fr)	1987-03-31	Nouveaux dérivés thiosulfonates, leur procédé de préparation ainsi que les compositions pharmaceutiques les contenant.
FR2693193B1 (fr)	1994-09-02	Nouveaux dérivés de la désacétyl-10 baccatine III, leur préparation et les compositions pharmaceutiques qui les contiennent.
IT1278108B1 (it)	1997-11-17	Secotassani dotati di attivita' antitumorale.
IT8920228A0 (it)	1989-04-20	Derivati di 5 idrossi, 5 acetil e 5 oxo pirrolidone, loro preparazione e composizioni farmaceutiche che li contengono.
YU42993A (sh)	1996-08-13	Stereoselektivni postupak glikozilacije za pripremanje 2'-deoksifluoronukleozida
IT1274356B (it)	1997-07-17	Tassani semisintetici odtati di attivita' antitumorale
RU94015185A (ru)	1995-12-20	Производные пиридина, их получение, фармацевтическая композиция, способ лечения

Legal Events

Date	Code	Title	Description
2015-12-21	MM1K	Lapsed by not paying the annual fees