NO980422L - Endotelinreseptorantagonister - Google Patents

Endotelinreseptorantagonister

Info

Publication number: NO980422L
Authority: NO; Norway
Prior art keywords: endothelin
Prior art date: 1995-08-02

Application number

NO980422A

Other languages

English (en)

Norwegian (no)

Other versions

NO980422D0 (no

Inventor

Juan Ignacio Luengo

John Duncan Elliott

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-02

Filing date

1998-01-30

Publication date

1998-03-24

1998-01-30 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1998-01-30 Publication of NO980422D0 publication Critical patent/NO980422D0/no

1998-03-24 Publication of NO980422L publication Critical patent/NO980422L/no

Links

102000002045 Endothelin Human genes 0.000 title 1
108050009340 Endothelin Proteins 0.000 title 1
ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)

NO980422A 1995-08-02 1998-01-30 Endotelinreseptorantagonister NO980422L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US179295P	1995-08-02	1995-08-02
US1098296P	1996-02-01	1996-02-01
PCT/US1996/012581 WO1997004772A1 (en)	1995-08-02	1996-08-02	Endothelin receptor antagonists

Publications (2)

Publication Number	Publication Date
NO980422D0 NO980422D0 (no)	1998-01-30
NO980422L true NO980422L (no)	1998-03-24

Family

ID=26669471

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO980422A NO980422L (no)	1995-08-02	1998-01-30	Endotelinreseptorantagonister

Country Status (25)

Country	Link
US (5)	US5969151A (de)
EP (2)	EP0843551B1 (de)
JP (2)	JP2001517195A (de)
KR (1)	KR19990036032A (de)
CN (1)	CN1196680A (de)
AP (1)	AP9801182A0 (de)
AT (1)	ATE341324T1 (de)
AU (2)	AU717172B2 (de)
BG (1)	BG102229A (de)
BR (1)	BR9609914A (de)
CA (2)	CA2228293A1 (de)
CZ (1)	CZ30498A3 (de)
DE (2)	DE69619116T2 (de)
EA (1)	EA000952B1 (de)
ES (2)	ES2171697T3 (de)
HU (1)	HU220776B1 (de)
MX (1)	MX9800975A (de)
NO (1)	NO980422L (de)
NZ (1)	NZ315846A (de)
OA (1)	OA10755A (de)
PL (1)	PL184272B1 (de)
RO (1)	RO115802B1 (de)
SK (1)	SK282584B6 (de)
TR (1)	TR199800152T1 (de)
WO (2)	WO1997004772A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR017426A1 (es) *	1997-12-08	2001-09-05	Smithkline Beecham Corp	Sal de monoargininilo del acido (e)-3-[1-n-butil-5-[2-(2-carboxifenil)metoxi-4-clorofenil]-1h-pirazol-4-il]-2-[(5-metoxi-2,3-dihidrobenzofuran-6-il)metil]-prop-2-enoico, composicion farmaceutica que la contiene, su uso para la manufactura de un medicamento y procedimiento para su preparacion
DE10155076A1 (de) *	2001-11-09	2003-05-22	Merck Patent Gmbh	Verwendung von Endothelin-Rezeptor-Antagonisten zur Behandlung von Tumorerkrankungen
US7087630B2 (en) *	2002-06-27	2006-08-08	Nitromed, Inc.	Cyclooxygenase 2 selective inhibitors, compositions and methods of use
WO2006075955A1 (en) *	2005-01-13	2006-07-20	Astrazeneca Ab	Pyrazolyl acylsulfonamide derivatives as endothelin converting enzyme inhibitors and useful in the treatment of chronic obstructive pulmonary disease
US7521435B2 (en) *	2005-02-18	2009-04-21	Pharma Diagnostics, N.V.	Silicon containing compounds having selective COX-2 inhibitory activity and methods of making and using the same
US8012038B1 (en)	2008-12-11	2011-09-06	Taylor Made Golf Company, Inc.	Golf club head
US10086240B1 (en)	2015-08-14	2018-10-02	Taylor Made Golf Company, Inc.	Golf club head
EP3380970B1 (de)	2015-11-24	2023-01-04	Sanford Burnham Prebys Medical Discovery Institute	Neuartige azolderivate als apelin-rezeptoragonisten
US10773135B1 (en)	2019-08-28	2020-09-15	Taylor Made Golf Company, Inc.	Golf club head

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1937241A1 (de) *	1968-08-02	1970-02-19	Sumitomo Chemical Co	3,5-Dioxopyrazolidinderivate und Verfahren zu ihrer Herstellung
JPH01211582A (ja) *	1988-02-16	1989-08-24	Tanabe Seiyaku Co Ltd	ベンゾジオキソール誘導体
EP0403158A3 (de) *	1989-06-14	1991-12-18	Smithkline Beecham Corporation	Imidazolyl-Alkensäuren
JP3214856B2 (ja) *	1990-12-14	2001-10-02	スミスクライン・ビーチャム・コーポレイション	イミダゾリル−アルケン酸
FR2682379B1 (fr) *	1991-10-09	1994-02-11	Rhone Poulenc Agrochimie	Nouveaux phenylpyrazoles fongicides.
WO1994022830A1 (en) *	1993-03-31	1994-10-13	Smithkline Beecham Corporation	Chemical compounds
AU675870B2 (en) *	1993-08-18	1997-02-20	Msd K.K.	Endothelin antagonistic heteroaromatic ring-fused cyclopentene derivatives
IL111613A0 (en) *	1993-11-12	1995-01-24	Rhone Poulenc Rorer Ltd	Substituted phenyl compounds, their preparation and pharmaceutical compositions containing them
DE69526738T2 (de) *	1994-09-02	2003-02-06	Smithkline Beecham Corp., Philadelphia	Endothelin-rezeptor-antagonisten

1996
- 1996-08-02 MX MX9800975A patent/MX9800975A/es not_active IP Right Cessation
- 1996-08-02 AT AT96928036T patent/ATE341324T1/de not_active IP Right Cessation
- 1996-08-02 WO PCT/US1996/012581 patent/WO1997004772A1/en not_active Ceased
- 1996-08-02 BR BR9609914A patent/BR9609914A/pt not_active Application Discontinuation
- 1996-08-02 EP EP96926243A patent/EP0843551B1/de not_active Expired - Lifetime
- 1996-08-02 CA CA002228293A patent/CA2228293A1/en not_active Abandoned
- 1996-08-02 SK SK113-98A patent/SK282584B6/sk unknown
- 1996-08-02 RO RO98-00135A patent/RO115802B1/ro unknown
- 1996-08-02 AP APAP/P/1998/001182A patent/AP9801182A0/en unknown
- 1996-08-02 JP JP50788797A patent/JP2001517195A/ja not_active Ceased
- 1996-08-02 NZ NZ315846A patent/NZ315846A/xx unknown
- 1996-08-02 EA EA199800185A patent/EA000952B1/ru not_active IP Right Cessation
- 1996-08-02 ES ES96926243T patent/ES2171697T3/es not_active Expired - Lifetime
- 1996-08-02 KR KR1019980700697A patent/KR19990036032A/ko not_active Ceased
- 1996-08-02 CZ CZ98304A patent/CZ30498A3/cs unknown
- 1996-08-02 CN CN96197111A patent/CN1196680A/zh active Pending
- 1996-08-02 JP JP9507907A patent/JPH11511133A/ja not_active Ceased
- 1996-08-02 WO PCT/US1996/012661 patent/WO1997004773A1/en not_active Ceased
- 1996-08-02 DE DE69619116T patent/DE69619116T2/de not_active Expired - Fee Related
- 1996-08-02 ES ES96928036T patent/ES2273350T3/es not_active Expired - Lifetime
- 1996-08-02 HU HU9902817A patent/HU220776B1/hu not_active IP Right Cessation
- 1996-08-02 AU AU67645/96A patent/AU717172B2/en not_active Ceased
- 1996-08-02 PL PL96324745A patent/PL184272B1/pl not_active IP Right Cessation
- 1996-08-02 TR TR1998/00152T patent/TR199800152T1/xx unknown
- 1996-08-02 CA CA002228296A patent/CA2228296A1/en not_active Abandoned
- 1996-08-02 AU AU66463/96A patent/AU6646396A/en not_active Abandoned
- 1996-08-02 DE DE69636597T patent/DE69636597T2/de not_active Expired - Fee Related
- 1996-08-02 EP EP96928036A patent/EP0841925B1/de not_active Expired - Lifetime
1998
- 1998-01-28 OA OA9800014A patent/OA10755A/en unknown
- 1998-01-30 NO NO980422A patent/NO980422L/no not_active Application Discontinuation
- 1998-02-02 BG BG102229A patent/BG102229A/xx unknown
- 1998-07-23 US US09/121,545 patent/US5969151A/en not_active Expired - Fee Related
1999
- 1999-01-08 US US09/227,361 patent/US5958968A/en not_active Expired - Fee Related
- 1999-06-29 US US09/342,989 patent/US6096897A/en not_active Expired - Fee Related
- 1999-12-14 US US09/460,487 patent/US6353116B1/en not_active Expired - Fee Related
2001
- 2001-11-30 US US10/021,461 patent/US6482956B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU717172B2 (en)	2000-03-16
KR19990036032A (ko)	1999-05-25
EP0843551A4 (de)	1998-08-12
DE69619116T2 (de)	2002-09-19
JP2001517195A (ja)	2001-10-02
AU6646396A (en)	1997-02-26
TR199800152T1 (xx)	1998-05-21
EP0843551A1 (de)	1998-05-27
AP9801182A0 (en)	1998-01-31
DE69636597D1 (de)	2006-11-16
US20020072614A1 (en)	2002-06-13
PL324745A1 (en)	1998-06-08
MX9800975A (es)	1998-04-30
US6096897A (en)	2000-08-01
PL184272B1 (pl)	2002-09-30
US6353116B1 (en)	2002-03-05
DE69636597T2 (de)	2007-08-16
CA2228293A1 (en)	1997-02-13
HUP9902817A3 (en)	2001-03-28
EP0843551B1 (de)	2002-02-06
ATE341324T1 (de)	2006-10-15
BR9609914A (pt)	1999-07-06
OA10755A (en)	2002-12-13
NO980422D0 (no)	1998-01-30
EP0841925A4 (de)	2001-10-17
HUP9902817A2 (hu)	1999-12-28
SK282584B6 (sk)	2002-10-08
AU6764596A (en)	1997-02-26
EP0841925A1 (de)	1998-05-20
NZ315846A (en)	1999-01-28
CA2228296A1 (en)	1997-02-13
EA000952B1 (ru)	2000-08-28
US6482956B2 (en)	2002-11-19
JPH11511133A (ja)	1999-09-28
EA199800185A1 (ru)	1998-10-29
EP0841925B1 (de)	2006-10-04
RO115802B1 (ro)	2000-06-30
ES2273350T3 (es)	2007-05-01
HU220776B1 (hu)	2002-05-28
CN1196680A (zh)	1998-10-21
DE69619116D1 (de)	2002-03-21
US5958968A (en)	1999-09-28
WO1997004773A1 (en)	1997-02-13
ES2171697T3 (es)	2002-09-16
WO1997004772A1 (en)	1997-02-13
CZ30498A3 (cs)	1998-07-15
BG102229A (en)	1998-09-30
US5969151A (en)	1999-10-19
SK11398A3 (en)	1998-07-08

Legal Events

Date	Code	Title	Description
2005-10-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO961072D0 (no)	1996-03-15	Endotelinreseptorantagonister
DE69619116D1 (de)	2002-03-21	Endothelinrezeptorantagonisten
NO963131D0 (no)	1996-07-26	Endotelinreseptorantagonister
DE69626986D1 (de)	2003-04-30	Endothelinrezeptorantagonist
NO963213D0 (no)	1996-08-01	Endotelinreseptorantagonister
ATE198470T1 (de)	2001-01-15	Alkenyl-benzoylguanidine
DE69628924D1 (de)	2003-08-07	Endothelinrezeptorantagonisten
ATE240972T1 (de)	2003-06-15	Cyclopeptolide
ATA119896A (de)	2002-04-15	Scheibenmähwerk
BR9503866A (pt)	1997-10-14	Autolabor
BR9501643A (pt)	1997-09-16	Helistato
SE9501165D0 (sv)	1995-03-31	Hållaranordning
KR960030307U (ko)	1996-10-22	다시
BR7501376U (pt)	1997-09-16	Massarreal
BR7502098U (pt)	1998-04-14	T-compacto
BR7500825U (pt)	1997-05-13	Chutegol
BR7500838U (pt)	1997-05-13	Vassourágua
BR7500991U (pt)	1996-06-18	Caríndio
BR7501298U (pt)	1997-09-16	Torre-audio-visual
BR7501299U (pt)	1997-09-16	Geladeira-prática
BR7501301U (pt)	1997-09-16	Guarda-chuva-mochila
BR7500703U (pt)	1997-05-13	Rodopratic
BR7501399U (pt)	1997-09-16	Ciclonavegador
BR7501437U (pt)	1997-11-18	Leiteira
BR7501467U (pt)	1997-11-18	Vassourágua