NO982873L - 1-metylkarbapenemderivater - Google Patents

1-metylkarbapenemderivater

Info

Publication number
NO982873L
NO982873L NO982873A NO982873A NO982873L NO 982873 L NO982873 L NO 982873L NO 982873 A NO982873 A NO 982873A NO 982873 A NO982873 A NO 982873A NO 982873 L NO982873 L NO 982873L
Authority
NO
Norway
Prior art keywords
substituted
ylcarbonyl
hydroxy
ethyl
methylcarbapenem
Prior art date
Application number
NO982873A
Other languages
English (en)
Other versions
NO310684B1 (no
NO982873D0 (no
Inventor
Isao Kawamoto
Yasuo Shimoji
Katsuya Ishikawa
Katsuhiko Kojima
Hiroshi Yasuda
Satoshi Ohya
Yukio Utsui
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO982873D0 publication Critical patent/NO982873D0/no
Publication of NO982873L publication Critical patent/NO982873L/no
Publication of NO310684B1 publication Critical patent/NO310684B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19982873A 1995-12-21 1998-06-19 1-metylkarbapenemderivater og farmasöytisk preparat inneholdende disse NO310684B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP33313595 1995-12-21
JP30894096 1996-11-20
PCT/JP1996/003726 WO1997023483A1 (fr) 1995-12-21 1996-12-20 Derives de 1-methylcarbapenem

Publications (3)

Publication Number Publication Date
NO982873D0 NO982873D0 (no) 1998-06-19
NO982873L true NO982873L (no) 1998-08-21
NO310684B1 NO310684B1 (no) 2001-08-13

Family

ID=26565749

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19982873A NO310684B1 (no) 1995-12-21 1998-06-19 1-metylkarbapenemderivater og farmasöytisk preparat inneholdende disse

Country Status (17)

Country Link
US (1) US6090802A (no)
EP (1) EP0882728B1 (no)
KR (1) KR100386993B1 (no)
CN (1) CN1095843C (no)
AT (1) ATE223411T1 (no)
AU (1) AU711135B2 (no)
CA (1) CA2241092C (no)
CZ (1) CZ298246B6 (no)
DE (1) DE69623497T2 (no)
DK (1) DK0882728T3 (no)
ES (1) ES2181927T3 (no)
HU (1) HUP9901376A3 (no)
MX (1) MX9805023A (no)
NO (1) NO310684B1 (no)
NZ (1) NZ324447A (no)
PT (1) PT882728E (no)
WO (1) WO1997023483A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ272099A3 (cs) 1997-02-07 1999-11-17 Kyoto Pharmaceutical Industries, Ltd. Karbapenémové sloučeniny, jejich použití a jejich meziprodukty
NZ508493A (en) 1998-05-01 2002-06-28 Kyoto Pharma Ind Carbapenem derivatives, utilization thereof and intermediate compounds of the same
AU1415500A (en) * 1998-12-07 2000-06-26 Sankyo Company Limited 1-methylcarbapenem derivatives
US7041660B2 (en) 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
TWI250160B (en) * 1999-07-06 2006-03-01 Sankyo Co Crystalline 1-methylcarbapenem compound
US6531594B2 (en) * 2000-08-24 2003-03-11 Mitsubishi Chemical Corporation Process for producing 1H-3-aminopyrrolidine and derivatives thereof
DE60116656T2 (de) * 2000-11-20 2006-09-21 Sankyo Co., Ltd. Verfahren zur Herstellung Antibakterieller Verbindungen vom Carbapenem-Typ
BR0209970A (pt) * 2001-05-21 2004-04-06 Kyoto Pharma Ind Composto de carbapenem
US6673829B2 (en) 2001-09-14 2004-01-06 Novo Nordisk A/S Aminoazetidine,-pyrrolidine and -piperidine derivatives
EP1430027B1 (en) 2001-09-14 2010-09-01 High Point Pharmaceuticals, LLC Novel aminoazetidine, -pyrrolidine and -piperidine derivatives
CN100475817C (zh) 2003-08-25 2009-04-08 三共株式会社 1-甲基碳青霉烯化合物的结晶
WO2006101062A1 (ja) * 2005-03-22 2006-09-28 Daiichi Sankyo Company, Limited 1-アルキルピロリジン構造を有するカルバペネム誘導体の製造方法
EP1880997A4 (en) * 2005-05-13 2009-03-11 Daiichi Sankyo Co Ltd CRYSTAL OF 1-METHYL CARBONENE COMPOUND
MY162532A (en) 2008-01-18 2017-06-15 Merck Sharp & Dohme Beta-lactamase inhibitors

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
CA1281720C (en) * 1984-11-08 1991-03-19 Makoto Sunagawa Carbapenem compounds and production thereof
JPS62155279A (ja) * 1984-11-08 1987-07-10 Sumitomo Pharmaceut Co Ltd 新規なβ−ラクタム化合物
JP3005045B2 (ja) * 1990-02-14 2000-01-31 住友製薬株式会社 新規なβ―ラクタム化合物及びその製造法
TW198034B (no) * 1990-03-27 1993-01-11 Manyu Seiyaku Kk
CA2070305A1 (en) * 1991-06-04 1992-12-05 Isao Kawamoto 1-methylcarbapenem derivatives, their preparation and their use as antibiotics
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
JP3048196B2 (ja) * 1991-06-20 2000-06-05 第一製薬株式会社 カルバペネム誘導体
HU218676B (hu) * 1992-03-11 2000-10-28 Sankyo Co. Ltd. Antimikrobiális karbapenemszármazékok, ilyen vegyületeket tartalmazó gyógyászati készítmények és eljárás ezek előállítására
JP3411589B2 (ja) * 1992-05-11 2003-06-03 第一製薬株式会社 カルバペネム誘導体
JP3344662B2 (ja) * 1992-09-14 2002-11-11 三共株式会社 カルバペネム−3−カルボン酸誘導体
JPH06199860A (ja) * 1992-09-16 1994-07-19 Sankyo Co Ltd カルバペネム誘導体
AU4912393A (en) * 1993-06-15 1994-12-22 Dong Kook Pharmaceutical Co., Ltd. 1-beta-methyl-2-thiolic carbapenem derivatives
GB9320816D0 (en) * 1993-10-08 1993-12-01 Fujisawa Pharmaceutical Co Novel compounds
RU2162088C2 (ru) * 1996-04-26 2001-01-20 Санкио Компани Лимитед 1-метилкарбапенем или его фармакологически приемлемые соли, композиция, способ предупреждения или лечения бактериальных инфекций

Also Published As

Publication number Publication date
US6090802A (en) 2000-07-18
DE69623497T2 (de) 2003-05-28
PT882728E (pt) 2002-11-29
ATE223411T1 (de) 2002-09-15
DK0882728T3 (da) 2003-01-06
EP0882728A4 (en) 1999-03-24
EP0882728A1 (en) 1998-12-09
CN1209130A (zh) 1999-02-24
NO310684B1 (no) 2001-08-13
MX9805023A (es) 1998-11-30
AU711135B2 (en) 1999-10-07
DE69623497D1 (de) 2002-10-10
EP0882728B1 (en) 2002-09-04
WO1997023483A1 (fr) 1997-07-03
CA2241092A1 (en) 1997-07-03
NO982873D0 (no) 1998-06-19
NZ324447A (en) 1999-08-30
KR100386993B1 (ko) 2003-12-18
ES2181927T3 (es) 2003-03-01
HUP9901376A3 (en) 2000-03-28
AU1171897A (en) 1997-07-17
CA2241092C (en) 2004-04-27
HK1015766A1 (en) 1999-10-22
HUP9901376A2 (hu) 1999-08-30
CZ191898A3 (cs) 1998-09-16
CZ298246B6 (cs) 2007-08-01
KR19990071960A (ko) 1999-09-27
CN1095843C (zh) 2002-12-11

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Legal Events

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