NO983283L - Hydrokamsyre-baserte Kollagenase-inhibitorer - Google Patents

Hydrokamsyre-baserte Kollagenase-inhibitorer

Info

Publication number
NO983283L
NO983283L NO983283A NO983283A NO983283L NO 983283 L NO983283 L NO 983283L NO 983283 A NO983283 A NO 983283A NO 983283 A NO983283 A NO 983283A NO 983283 L NO983283 L NO 983283L
Authority
NO
Norway
Prior art keywords
hydrocamic
acid
collagenase inhibitors
alkenyl
aryl
Prior art date
Application number
NO983283A
Other languages
English (en)
Norwegian (no)
Other versions
NO983283D0 (no
Inventor
Stuart Bailey
Derek Richard Buckle
Andrew Faller
David Glynn Smith
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO983283D0 publication Critical patent/NO983283D0/no
Publication of NO983283L publication Critical patent/NO983283L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO983283A 1996-01-17 1998-07-16 Hydrokamsyre-baserte Kollagenase-inhibitorer NO983283L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9601041.8A GB9601041D0 (en) 1996-01-17 1996-01-17 Novel compounds
PCT/EP1997/000196 WO1997026257A1 (fr) 1996-01-17 1997-01-14 Inhibiteurs de la collagenase, a base d'acide hydroxamique

Publications (2)

Publication Number Publication Date
NO983283D0 NO983283D0 (no) 1998-07-16
NO983283L true NO983283L (no) 1998-09-16

Family

ID=10787226

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983283A NO983283L (no) 1996-01-17 1998-07-16 Hydrokamsyre-baserte Kollagenase-inhibitorer

Country Status (19)

Country Link
EP (1) EP0912545A1 (fr)
JP (1) JP2000503312A (fr)
KR (1) KR19990077325A (fr)
CN (1) CN1213368A (fr)
AR (1) AR005472A1 (fr)
AU (1) AU725056B2 (fr)
BR (1) BR9707024A (fr)
CA (1) CA2242913A1 (fr)
CZ (1) CZ222498A3 (fr)
GB (1) GB9601041D0 (fr)
HU (1) HUP9901022A3 (fr)
IL (1) IL125381A0 (fr)
NO (1) NO983283L (fr)
NZ (1) NZ326352A (fr)
PL (1) PL327820A1 (fr)
TR (1) TR199801380T2 (fr)
TW (1) TW462967B (fr)
WO (1) WO1997026257A1 (fr)
ZA (1) ZA97345B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
GB9609795D0 (en) * 1996-05-10 1996-07-17 Smithkline Beecham Plc Novel compounds
AU1960100A (en) * 1999-01-06 2000-07-24 Mcmaster University Method of preventing immune and hypersensitivity reactions
GB9922825D0 (en) * 1999-09-25 1999-11-24 Smithkline Beecham Biolog Medical use
AU2001271068A1 (en) * 2000-07-18 2002-01-30 Chugai Seiyaku Kabushiki Kaisha Matrix metalloprotease inhibitors
WO2003064472A2 (fr) * 2002-01-28 2003-08-07 Aimsco Limited Traitement
US7521563B2 (en) 2004-08-10 2009-04-21 Shizuoka Coffein Co., Ltd. Hydroxamic acid derivative and medicine containing the same as active ingredient
KR100844277B1 (ko) * 2005-04-29 2008-07-07 (주)아모레퍼시픽 히드록삼산 유도체 및 이의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743587A (en) * 1985-09-10 1988-05-10 G. D. Searle & Co. Hydroxamic acid based collagenase inhibitors
GB8827305D0 (en) * 1988-11-23 1988-12-29 British Bio Technology Compounds
GB9504084D0 (en) * 1995-03-01 1995-04-19 British Biotech Pharm Synthesis of carboxylic and hydroxamic acid derivatives

Also Published As

Publication number Publication date
JP2000503312A (ja) 2000-03-21
HUP9901022A3 (en) 2001-11-28
NO983283D0 (no) 1998-07-16
TW462967B (en) 2001-11-11
CN1213368A (zh) 1999-04-07
NZ326352A (en) 2000-03-27
EP0912545A1 (fr) 1999-05-06
CA2242913A1 (fr) 1997-07-24
AU725056B2 (en) 2000-10-05
TR199801380T2 (xx) 1998-10-21
BR9707024A (pt) 1999-07-20
ZA97345B (en) 1998-07-16
WO1997026257A1 (fr) 1997-07-24
IL125381A0 (en) 1999-03-12
CZ222498A3 (cs) 1999-03-17
AU1443697A (en) 1997-08-11
HUP9901022A2 (hu) 1999-07-28
GB9601041D0 (en) 1996-03-20
PL327820A1 (en) 1999-01-04
AR005472A1 (es) 1999-06-23
KR19990077325A (ko) 1999-10-25

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application