NO983830L - Nye substituerte N-metyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl)benzamider som er anvendbare for behandling av allergiske sykdommer - Google Patents

Nye substituerte N-metyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl)benzamider som er anvendbare for behandling av allergiske sykdommer

Info

Publication number: NO983830L
Authority: NO; Norway
Prior art keywords: benzimidazol; piperidin; aryl; butyl; amino
Prior art date: 1996-02-21

Application number

NO983830A

Other languages

English (en)

Norwegian (no)

Other versions

NO983830D0 (no

Inventor

George Daniel Maynard

John Michael Kane

Elizabeth Mary Kudlacz

Christopher Robin Dalton

Braulio Santiago

Larry Don Bratton

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-21

Filing date

1998-08-20

Publication date

1998-10-20

1997-01-06 Priority claimed from US08/778,996 external-priority patent/US5922737A/en

1998-08-20 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1998-08-20 Publication of NO983830D0 publication Critical patent/NO983830D0/no

1998-10-20 Publication of NO983830L publication Critical patent/NO983830L/no

Links

-1 4- (1H-benzimidazol-2-yl-amino) piperidin-1-yl Chemical group 0.000 title 1
208000026935 allergic disease Diseases 0.000 title 1
125000003118 aryl group Chemical group 0.000 title 1
229940054066 benzamide antipsychotics Drugs 0.000 title 1
150000003936 benzamides Chemical class 0.000 title 1
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO983830A 1996-02-21 1998-08-20 Nye substituerte N-metyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl)benzamider som er anvendbare for behandling av allergiske sykdommer NO983830L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US60421696A	1996-02-21	1996-02-21
US08/778,996 US5922737A (en)	1996-02-21	1997-01-06	Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
PCT/US1997/001571 WO1997030989A1 (fr)	1996-02-21	1997-01-29	Nouveaux n-methyl-n-(4-(4-(1h-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl) benzamides substitues convenant au traitement de maladies allergiques

Publications (2)

Publication Number	Publication Date
NO983830D0 NO983830D0 (no)	1998-08-20
NO983830L true NO983830L (no)	1998-10-20

Family

ID=27084615

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO983830A NO983830L (no)	1996-02-21	1998-08-20	Nye substituerte N-metyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl)benzamider som er anvendbare for behandling av allergiske sykdommer

Country Status (19)

Country	Link
EP (1)	EP0888336B1 (fr)
JP (1)	JP2001504798A (fr)
KR (1)	KR19990087131A (fr)
CN (1)	CN1115341C (fr)
AR (1)	AR005896A1 (fr)
AT (1)	ATE221882T1 (fr)
AU (1)	AU710488B2 (fr)
BR (1)	BR9707652A (fr)
CA (1)	CA2247105C (fr)
DE (1)	DE69714579T2 (fr)
DK (1)	DK0888336T3 (fr)
ES (1)	ES2176687T3 (fr)
HU (1)	HUP9901030A3 (fr)
IL (1)	IL125578A (fr)
NO (1)	NO983830L (fr)
NZ (1)	NZ330908A (fr)
PT (1)	PT888336E (fr)
TW (1)	TW562804B (fr)
WO (1)	WO1997030989A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6423704B2 (en)	1995-12-20	2002-07-23	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en)	1995-12-20	2001-02-27	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
DK1499316T3 (da) *	2002-04-18	2008-07-21	Schering Corp	(1-4-piperidinyl)benzimidazolderivater anvendelige som histamin-H3-antagonister
EP1539742B1 (fr) *	2002-06-24	2006-11-08	Schering Corporation	Derives d'indole utilises en tant qu'antagonistes h3 d'histamine
GB0315203D0 (en) *	2003-06-28	2003-08-06	Celltech R&D Ltd	Chemical compounds
JP2010516734A (ja)	2007-01-24	2010-05-20	グラクソグループリミテッド	３，５−ジアミノ−６−（２，３−ジクロロフェニル）−１，２，４−トリアジンまたはｒ（−）−２，４−ジアミノ−５−（２，３−ジクロロフェニル）−６−フルオロメチルピリミジンを含む医薬組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
FR2676054B1 (fr) *	1991-05-03	1993-09-03	Sanofi Elf	Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
DE69508093T2 (de) *	1994-08-25	1999-07-15	Merrell Pharmaceuticals Inc., Cincinnati, Ohio	Substituierte piperidine für die behandlung von allergischen krankheiten

1997
- 1997-01-29 AT AT97905689T patent/ATE221882T1/de not_active IP Right Cessation
- 1997-01-29 KR KR1019980706522A patent/KR19990087131A/ko not_active Abandoned
- 1997-01-29 EP EP97905689A patent/EP0888336B1/fr not_active Expired - Lifetime
- 1997-01-29 PT PT97905689T patent/PT888336E/pt unknown
- 1997-01-29 IL IL12557897A patent/IL125578A/en not_active IP Right Cessation
- 1997-01-29 BR BR9707652A patent/BR9707652A/pt not_active IP Right Cessation
- 1997-01-29 JP JP53016697A patent/JP2001504798A/ja not_active Abandoned
- 1997-01-29 CN CN97192390A patent/CN1115341C/zh not_active Expired - Fee Related
- 1997-01-29 WO PCT/US1997/001571 patent/WO1997030989A1/fr not_active Ceased
- 1997-01-29 AU AU22519/97A patent/AU710488B2/en not_active Ceased
- 1997-01-29 ES ES97905689T patent/ES2176687T3/es not_active Expired - Lifetime
- 1997-01-29 HU HU9901030A patent/HUP9901030A3/hu unknown
- 1997-01-29 CA CA002247105A patent/CA2247105C/fr not_active Expired - Fee Related
- 1997-01-29 DK DK97905689T patent/DK0888336T3/da active
- 1997-01-29 DE DE69714579T patent/DE69714579T2/de not_active Expired - Fee Related
- 1997-01-29 NZ NZ330908A patent/NZ330908A/en unknown
- 1997-02-18 TW TW086101887A patent/TW562804B/zh not_active IP Right Cessation
- 1997-02-19 AR ARP970100645A patent/AR005896A1/es not_active Application Discontinuation
1998
- 1998-08-20 NO NO983830A patent/NO983830L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP9901030A2 (hu)	1999-07-28
WO1997030989A1 (fr)	1997-08-28
CN1211246A (zh)	1999-03-17
NO983830D0 (no)	1998-08-20
TW562804B (en)	2003-11-21
EP0888336A1 (fr)	1999-01-07
EP0888336B1 (fr)	2002-08-07
AU2251997A (en)	1997-09-10
BR9707652A (pt)	1999-07-27
NZ330908A (en)	2001-04-27
AU710488B2 (en)	1999-09-23
AR005896A1 (es)	1999-07-21
CN1115341C (zh)	2003-07-23
KR19990087131A (ko)	1999-12-15
ES2176687T3 (es)	2002-12-01
DK0888336T3 (da)	2002-12-02
PT888336E (pt)	2002-12-31
IL125578A (en)	2002-09-12
JP2001504798A (ja)	2001-04-10
ATE221882T1 (de)	2002-08-15
IL125578A0 (en)	1999-03-12
HUP9901030A3 (en)	2002-01-28
HK1019734A1 (en)	2000-02-25
CA2247105A1 (fr)	1997-08-28
DE69714579D1 (de)	2002-09-12
DE69714579T2 (de)	2003-04-10
CA2247105C (fr)	2002-05-14

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Legal Events

Date	Code	Title	Description
2005-10-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application