NO984084L - 4-Amino-pyrimidin-derivater, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte ved fremstilling derav - Google Patents
4-Amino-pyrimidin-derivater, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte ved fremstilling deravInfo
- Publication number
- NO984084L NO984084L NO984084A NO984084A NO984084L NO 984084 L NO984084 L NO 984084L NO 984084 A NO984084 A NO 984084A NO 984084 A NO984084 A NO 984084A NO 984084 L NO984084 L NO 984084L
- Authority
- NO
- Norway
- Prior art keywords
- amino
- preparation
- pyrimidine derivatives
- compounds
- medicaments containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Den foreliggende oppfinnelse vedrører 4-amino-pyrimidin-derivater med den generelle formel hvor Ra. Rb- A og B er som definert i krav 1, deres tautomerer, deres stereoisomerer og deres salter, spesielt deres fysiologisk akseptable salter med uorganiske eller organiske syrer eller baser, og som har verdifulle farmakologiske egenskaper, særlig en hemmende virkning på signaltransduksjonen formidlet gjennom tyrosin- kinaser, deres anvendelse for behandling av sykdommer, særlig tumorsykdom- mer, og deres fremstilling.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1996108631 DE19608631A1 (de) | 1996-03-06 | 1996-03-06 | 4-Amino-pyrimidin-Derivate, diese Verbindungen enthaltende Arnzeimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| DE19629652A DE19629652A1 (de) | 1996-03-06 | 1996-07-23 | 4-Amino-pyrimidin-Derivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| PCT/EP1997/001057 WO1997032881A1 (de) | 1996-03-06 | 1997-03-03 | 4-amino-pyrimidin-derivate, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO984084D0 NO984084D0 (no) | 1998-09-04 |
| NO984084L true NO984084L (no) | 1998-09-04 |
Family
ID=26023531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO984084A NO984084L (no) | 1996-03-06 | 1998-09-04 | 4-Amino-pyrimidin-derivater, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmÕte ved fremstilling derav |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0885226A1 (no) |
| JP (1) | JP2000506847A (no) |
| KR (1) | KR19990087550A (no) |
| CN (1) | CN1212695A (no) |
| AU (1) | AU710274B2 (no) |
| BG (1) | BG102708A (no) |
| BR (1) | BR9708312A (no) |
| CA (1) | CA2243994A1 (no) |
| CZ (1) | CZ281798A3 (no) |
| DE (1) | DE19629652A1 (no) |
| EE (1) | EE9800277A (no) |
| HU (1) | HUP9901820A3 (no) |
| IL (1) | IL125404A0 (no) |
| NO (1) | NO984084L (no) |
| NZ (1) | NZ331546A (no) |
| PL (1) | PL328771A1 (no) |
| SK (1) | SK120598A3 (no) |
| TR (1) | TR199801749T2 (no) |
| WO (1) | WO1997032881A1 (no) |
Families Citing this family (99)
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| DE69720965T2 (de) | 1996-02-13 | 2004-02-05 | Astrazeneca Ab | Chinazolinderivate und deren verwendung als vegf hemmer |
| NZ331191A (en) | 1996-03-05 | 2000-03-27 | Zeneca Ltd | 4-anilinoquinazoline derivatives and pharmaceutical compositions thereof |
| EP1396489A1 (en) * | 1999-01-27 | 2004-03-10 | Pfizer Products Inc. | Heteroaromatic bicyclic derivatives useful as anticancer agents |
| UA71945C2 (en) * | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
| KR100881105B1 (ko) | 1999-11-05 | 2009-02-02 | 아스트라제네카 아베 | Ｖｅｇｆ 억제제로서의 퀴나졸린 유도체 |
| BRPI0411608A (pt) * | 2003-06-24 | 2006-08-08 | Neurosearch As | derivado de 8-aza-biciclo [3.2.1] octano, composição farmacêutica, uso do composto, e, método de tratamento, prevenção ou alìvio de uma doença, um distúrbio ou uma condição de um organismo animal vivo |
| MX2007010068A (es) * | 2005-02-16 | 2007-10-10 | Schering Corp | Piperazino-piperidinas con actividad antagonista de cxcr3. |
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Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| DE4431867A1 (de) * | 1994-09-07 | 1996-03-14 | Thomae Gmbh Dr K | Pyrimido[5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
-
1996
- 1996-07-23 DE DE19629652A patent/DE19629652A1/de not_active Ceased
-
1997
- 1997-03-03 NZ NZ331546A patent/NZ331546A/xx unknown
- 1997-03-03 EP EP97907066A patent/EP0885226A1/de not_active Ceased
- 1997-03-03 BR BR9708312A patent/BR9708312A/pt not_active IP Right Cessation
- 1997-03-03 CZ CZ982817A patent/CZ281798A3/cs unknown
- 1997-03-03 CN CN97192787A patent/CN1212695A/zh active Pending
- 1997-03-03 WO PCT/EP1997/001057 patent/WO1997032881A1/de not_active Ceased
- 1997-03-03 PL PL97328771A patent/PL328771A1/xx unknown
- 1997-03-03 CA CA002243994A patent/CA2243994A1/en not_active Abandoned
- 1997-03-03 HU HU9901820A patent/HUP9901820A3/hu unknown
- 1997-03-03 KR KR1019980706987A patent/KR19990087550A/ko not_active Withdrawn
- 1997-03-03 JP JP9531444A patent/JP2000506847A/ja active Pending
- 1997-03-03 IL IL12540497A patent/IL125404A0/xx unknown
- 1997-03-03 SK SK1205-98A patent/SK120598A3/sk unknown
- 1997-03-03 TR TR1998/01749T patent/TR199801749T2/xx unknown
- 1997-03-03 EE EE9800277A patent/EE9800277A/xx unknown
- 1997-03-03 AU AU19251/97A patent/AU710274B2/en not_active Ceased
-
1998
- 1998-08-20 BG BG102708A patent/BG102708A/xx unknown
- 1998-09-04 NO NO984084A patent/NO984084L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK120598A3 (en) | 1999-06-11 |
| NO984084D0 (no) | 1998-09-04 |
| PL328771A1 (en) | 1999-02-15 |
| HUP9901820A2 (hu) | 1999-09-28 |
| BG102708A (en) | 1999-09-30 |
| IL125404A0 (en) | 1999-03-12 |
| HUP9901820A3 (en) | 2001-10-29 |
| CA2243994A1 (en) | 1997-09-12 |
| NZ331546A (en) | 2000-03-27 |
| DE19629652A1 (de) | 1998-01-29 |
| CN1212695A (zh) | 1999-03-31 |
| AU710274B2 (en) | 1999-09-16 |
| EP0885226A1 (de) | 1998-12-23 |
| TR199801749T2 (xx) | 1998-12-21 |
| JP2000506847A (ja) | 2000-06-06 |
| AU1925197A (en) | 1997-09-22 |
| KR19990087550A (ko) | 1999-12-27 |
| EE9800277A (et) | 1999-02-15 |
| CZ281798A3 (cs) | 1999-02-17 |
| WO1997032881A1 (de) | 1997-09-12 |
| BR9708312A (pt) | 1999-08-03 |
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