NO984345D0 - FremgangsmÕte for vevsinduksjon ved anvendelse av en kombinasjon av benmorfogenisk protein og paratyroid hormon-relatert peptid - Google Patents

FremgangsmÕte for vevsinduksjon ved anvendelse av en kombinasjon av benmorfogenisk protein og paratyroid hormon-relatert peptid

Info

Publication number
NO984345D0
NO984345D0 NO984345A NO984345A NO984345D0 NO 984345 D0 NO984345 D0 NO 984345D0 NO 984345 A NO984345 A NO 984345A NO 984345 A NO984345 A NO 984345A NO 984345 D0 NO984345 D0 NO 984345D0
Authority
NO
Norway
Prior art keywords
combination
proteins
parathyroid hormone
compositions
related peptide
Prior art date
Application number
NO984345A
Other languages
English (en)
Norwegian (no)
Other versions
NO984345L (no
Inventor
Gary Hattersley
Vicki A Rosen
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of NO984345L publication Critical patent/NO984345L/no
Publication of NO984345D0 publication Critical patent/NO984345D0/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
NO984345A 1996-03-26 1998-09-18 FremgangsmÕte for vevsinduksjon ved anvendelse av en kombinasjon av benmorfogenisk protein og paratyroid hormon-relatert peptid NO984345D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/622,101 US5700774A (en) 1996-03-26 1996-03-26 Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
PCT/US1997/004162 WO1997035607A1 (en) 1996-03-26 1997-03-17 Methods of tissue induction using a combination of bone morphogenetic protein and parathyroid hormone-related peptide

Publications (2)

Publication Number Publication Date
NO984345L NO984345L (no) 1998-09-18
NO984345D0 true NO984345D0 (no) 1998-09-18

Family

ID=24492945

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984345A NO984345D0 (no) 1996-03-26 1998-09-18 FremgangsmÕte for vevsinduksjon ved anvendelse av en kombinasjon av benmorfogenisk protein og paratyroid hormon-relatert peptid

Country Status (12)

Country Link
US (2) US5700774A (de)
EP (1) EP0906120B1 (de)
JP (1) JP2000507944A (de)
KR (1) KR19990087489A (de)
AT (1) ATE219685T1 (de)
AU (1) AU727312B2 (de)
CA (1) CA2249212A1 (de)
DE (1) DE69713597T2 (de)
FI (1) FI981916L (de)
NO (1) NO984345D0 (de)
OA (1) OA10885A (de)
WO (1) WO1997035607A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
ATE238417T1 (de) 1991-11-04 2003-05-15 Inst Genetics Llc Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US5906827A (en) * 1994-06-03 1999-05-25 Creative Biomolecules, Inc. Matrix for the manufacture of autogenous replacement body parts
GB9721797D0 (en) * 1997-10-14 1997-12-17 Univ Cardiff Materials and methods relating to cartilage repair
EP1034269A1 (de) * 1997-11-28 2000-09-13 Roche Diagnostics GmbH Aktive hedgehog-protein-mutante, verfahren zur herstellung und verwendung als arzneimittel
US6897297B1 (en) * 1997-12-03 2005-05-24 Curis, Inc. Hydrophobically-modified protein compositions and methods
US6171340B1 (en) 1998-02-27 2001-01-09 Mcdowell Charles L. Method and device for regenerating cartilage in articulating joints
EP0953576B1 (de) * 1998-04-30 2005-11-02 Curis, Inc. Aktives Hedgehog-Protein-Konjugat, Verfahren zur Herstellung und Verwendung
ATE250423T1 (de) 1998-07-13 2003-10-15 Univ Southern California Verfahren zur beschleunigen den zuwachs und heilen von knochen und knorpel
US6916783B2 (en) * 1998-07-13 2005-07-12 University Of Southern California Methods for accelerating bone and cartilage growth and repair
US7067144B2 (en) * 1998-10-20 2006-06-27 Omeros Corporation Compositions and methods for systemic inhibition of cartilage degradation
US6727224B1 (en) * 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
US6197061B1 (en) * 1999-03-01 2001-03-06 Koichi Masuda In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage
ES2525553T3 (es) 1999-03-25 2014-12-26 Metabolix, Inc. Dispositivos y aplicaciones médicas de polímeros polihidroxialcanoato
US6315992B1 (en) 1999-06-30 2001-11-13 Tissuegene Co. Generating cartilage in a mammal using fibroblasts transfected with a vector encoding TGF-β-1
US7338655B1 (en) 1999-06-30 2008-03-04 Tissuegene, Inc. Gene therapy using TGF-β
RU2271825C2 (ru) * 1999-07-21 2006-03-20 Омерос Корпорейшн Растворы и способы ингибирования боли, воспаления и разрушения хряща
US7687462B2 (en) * 1999-10-05 2010-03-30 The Regents Of The University Of California Composition for promoting cartilage formation or repair comprising a nell gene product and method of treating cartilage-related conditions using such composition
PT1223990E (pt) 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
US6702821B2 (en) 2000-01-14 2004-03-09 The Bonutti 2003 Trust A Instrumentation for minimally invasive joint replacement and methods for using same
US6770078B2 (en) 2000-01-14 2004-08-03 Peter M. Bonutti Movable knee implant and methods therefor
US7104996B2 (en) 2000-01-14 2006-09-12 Marctec. Llc Method of performing surgery
US7635390B1 (en) 2000-01-14 2009-12-22 Marctec, Llc Joint replacement component having a modular articulating surface
EP1312378A4 (de) * 2000-08-16 2004-03-17 Chugai Pharmaceutical Co Ltd Substanzen zur verbesserung der symptome bei gelenkserkrankungen
EP1399023B1 (de) 2001-06-01 2008-04-30 Wyeth Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US7708741B1 (en) 2001-08-28 2010-05-04 Marctec, Llc Method of preparing bones for knee replacement surgery
AU2002335747B2 (en) 2001-09-15 2009-01-29 Rush University Medical Center Stratified cartilage tissue and methods to engineer same
AU2002337807A1 (en) * 2001-10-04 2003-04-14 Massachusetts Institute Of Technology Effect of bone morphogenetic proteins on engineered cartilage
US20030165473A1 (en) * 2001-11-09 2003-09-04 Rush-Presbyterian-St. Luke's Medical Center Engineered intervertebral disc tissue
AU2003207512B2 (en) * 2002-01-10 2008-06-12 Osteotrophin Llc Treatment of bone disorders with skeletal anabolic drugs
WO2003077852A2 (en) * 2002-03-12 2003-09-25 Tissuegene, Inc. CARTILAGE REGENERATION USING CHONDROCYTE AND TGF-β
US7431922B2 (en) * 2002-03-29 2008-10-07 Tissuegene, Inc. Bioadhesive directed somatic cell therapy
US7005127B2 (en) * 2002-03-29 2006-02-28 Tissuegene, Inc. Mixed-cell gene therapy
AU2003280130B2 (en) 2002-06-28 2009-06-11 Centocor, Inc. Mammalian CH1 deleted mimetibodies, compositions, methods and uses
AU2003259765B2 (en) * 2002-08-13 2009-01-22 Wyeth Peptides as solubilizing excipients for transforming growth factor Beta proteins
US20050209142A1 (en) * 2002-11-20 2005-09-22 Goran Bertilsson Compounds and methods for increasing neurogenesis
US7837690B2 (en) 2003-01-15 2010-11-23 Biomet Manufacturing Corp. Method and apparatus for less invasive knee resection
US7789885B2 (en) 2003-01-15 2010-09-07 Biomet Manufacturing Corp. Instrumentation for knee resection
US7887542B2 (en) 2003-01-15 2011-02-15 Biomet Manufacturing Corp. Method and apparatus for less invasive knee resection
US8551100B2 (en) 2003-01-15 2013-10-08 Biomet Manufacturing, Llc Instrumentation for knee resection
AU2004226421A1 (en) * 2003-03-27 2004-10-14 Children's Hospital Medical Center Use of FGF- 18 protein, target proteins and their respective encoding nucleotide sequences to induce cartilage formation
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
AU2004272072B2 (en) 2003-09-12 2010-07-08 Etex Corporation Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins
US7488324B1 (en) 2003-12-08 2009-02-10 Biomet Manufacturing Corporation Femoral guide for implanting a femoral knee prosthesis
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20090319045A1 (en) 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
WO2006081379A1 (en) * 2005-01-26 2006-08-03 Wyeth Use of sfrps as markers of bmp activity
EP1851237A4 (de) 2005-02-16 2009-01-07 Univ California Pharmazeutische zusammensetzungen zur behandlung oder prävention von knochenerkrankungen
US7695479B1 (en) 2005-04-12 2010-04-13 Biomet Manufacturing Corp. Femoral sizer
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US7622438B1 (en) 2005-07-18 2009-11-24 Acologix, Inc. Protein formulation for promoting hard tissue formation
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US9113971B2 (en) 2006-02-27 2015-08-25 Biomet Manufacturing, Llc Femoral acetabular impingement guide
US9345548B2 (en) 2006-02-27 2016-05-24 Biomet Manufacturing, Llc Patient-specific pre-operative planning
US20150335438A1 (en) 2006-02-27 2015-11-26 Biomet Manufacturing, Llc. Patient-specific augments
US9339278B2 (en) 2006-02-27 2016-05-17 Biomet Manufacturing, Llc Patient-specific acetabular guides and associated instruments
US8603180B2 (en) 2006-02-27 2013-12-10 Biomet Manufacturing, Llc Patient-specific acetabular alignment guides
US9907659B2 (en) 2007-04-17 2018-03-06 Biomet Manufacturing, Llc Method and apparatus for manufacturing an implant
US10278711B2 (en) 2006-02-27 2019-05-07 Biomet Manufacturing, Llc Patient-specific femoral guide
US8407067B2 (en) 2007-04-17 2013-03-26 Biomet Manufacturing Corp. Method and apparatus for manufacturing an implant
US7780672B2 (en) 2006-02-27 2010-08-24 Biomet Manufacturing Corp. Femoral adjustment device and associated method
US8591516B2 (en) 2006-02-27 2013-11-26 Biomet Manufacturing, Llc Patient-specific orthopedic instruments
US9289253B2 (en) 2006-02-27 2016-03-22 Biomet Manufacturing, Llc Patient-specific shoulder guide
US9173661B2 (en) 2006-02-27 2015-11-03 Biomet Manufacturing, Llc Patient specific alignment guide with cutting surface and laser indicator
US8070752B2 (en) 2006-02-27 2011-12-06 Biomet Manufacturing Corp. Patient specific alignment guide and inter-operative adjustment
US9918740B2 (en) 2006-02-27 2018-03-20 Biomet Manufacturing, Llc Backup surgical instrument system and method
US7695520B2 (en) 2006-05-31 2010-04-13 Biomet Manufacturing Corp. Prosthesis and implementation system
US9795399B2 (en) 2006-06-09 2017-10-24 Biomet Manufacturing, Llc Patient-specific knee alignment guide and associated method
ES2542509T3 (es) * 2007-01-22 2015-08-06 Orthotrophix, Inc. Una composición peptídica y un método de estimulación de la formación de cartílago
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US8513193B2 (en) 2008-10-13 2013-08-20 University Of Rochester Protecting and repairing cartilage and musculoskeletal soft tissues
CA2744445C (en) 2008-11-25 2023-10-24 Tissuegene, Inc. Primed cell therapy
US8530420B2 (en) * 2008-12-16 2013-09-10 Kaohsiung Medical University Treatment of arthritis with parathyroid hormone
US9968376B2 (en) 2010-11-29 2018-05-15 Biomet Manufacturing, Llc Patient-specific orthopedic instruments
US9241745B2 (en) 2011-03-07 2016-01-26 Biomet Manufacturing, Llc Patient-specific femoral version guide
CA2918486C (en) * 2012-07-20 2020-12-08 The Regents Of The University Of California Methods for producing cartilage and bone
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US20190381341A1 (en) * 2017-02-01 2019-12-19 The Johns Hopkins University Parathyroid hormone and regeneration of degenerative discs disease
US10722310B2 (en) 2017-03-13 2020-07-28 Zimmer Biomet CMF and Thoracic, LLC Virtual surgery planning system and method

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459047A (en) * 1986-07-01 1995-10-17 Genetics Institute, Inc. BMP-6 proteins
US5187076A (en) * 1986-07-01 1993-02-16 Genetics Institute, Inc. DNA sequences encoding BMP-6 proteins
US5106748A (en) * 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
ZA874681B (en) * 1986-07-01 1988-04-27 Genetics Inst Novel osteoinductive factors
US5543394A (en) * 1986-07-01 1996-08-06 Genetics Institute, Inc. Bone morphogenetic protein 5(BMP-5) compositions
US5013649A (en) * 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US5108922A (en) * 1986-07-01 1992-04-28 Genetics Institute, Inc. DNA sequences encoding BMP-1 products
US5457092A (en) * 1987-07-30 1995-10-10 Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) Methods of promoting bone growth in mammals comprising administration of modified parathyroid hormone
US5457047A (en) * 1989-02-23 1995-10-10 Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) DNA Sequences coding for PTH variants, PTH variants, expression vector, bacterial host, use and therapeutic composition
JPH06500991A (ja) * 1990-05-16 1994-01-27 ジェネティックス・インスティテュート・インコーポレイテッド 骨および軟骨誘導蛋白質
US5364839A (en) * 1990-06-18 1994-11-15 Genetics Institute, Inc. Osteoinductive pharmaceutical formulations
US5118667A (en) * 1991-05-03 1992-06-02 Celtrix Pharmaceuticals, Inc. Bone growth factors and inhibitors of bone resorption for promoting bone formation
WO1993000050A1 (en) * 1991-06-21 1993-01-07 Genetics Institute, Inc. Pharmaceutical formulations of osteogenic proteins
AU652472B2 (en) * 1991-06-25 1994-08-25 Genetics Institute, Llc BMP-9 compositions
ATE238417T1 (de) * 1991-11-04 2003-05-15 Inst Genetics Llc Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
DK0625989T3 (da) * 1992-02-12 2000-06-26 Bioph Biotech Entw Pharm Gmbh DNA-sekvenser kodende for hidtil ukendte vækst-/differentieringsfaktorer
IL106278A0 (en) * 1992-07-13 1993-11-15 Sumitomo Metal Ind Bone formation-inducing protein
EP0678101A4 (de) * 1993-01-12 1997-07-16 Univ Johns Hopkins Med Wachstums-differenzierungsfaktor-9.
WO1994015965A1 (en) * 1993-01-12 1994-07-21 Johns Hopkins University School Of Medicine Growth differentiation factor-3
JP3645258B2 (ja) * 1993-01-12 2005-05-11 ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 増殖分化因子−５
DK0690873T3 (da) * 1993-03-19 2003-09-29 Univ Johns Hopkins Med Vækstdifferentieringsfaktor-8
EP0698095B1 (de) * 1993-05-12 2004-04-28 Genetics Institute, LLC Bmp-10 zusammensetzungen
BR9406715A (pt) * 1993-05-12 1996-02-06 Genetics Inst Molécula de DNA isolada célula hospedeira vetor método para produzir uma proteina (BMP-11) polipeptideo de proteina-11 morfogenética de osso purificada (BMP-11) e molécula de DNA quimérica
EP0717633A4 (de) * 1993-07-09 1998-05-20 Univ Johns Hopkins Med Wachstums-differenzierungsfaktor-7
CA2165776A1 (en) * 1993-07-09 1995-01-19 The Johns Hopkins University School Of Medicine Growth differentiation factor-6
DE69434651T2 (de) * 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen

Also Published As

Publication number Publication date
NO984345L (no) 1998-09-18
US5700774A (en) 1997-12-23
WO1997035607A1 (en) 1997-10-02
DE69713597D1 (de) 2002-08-01
ATE219685T1 (de) 2002-07-15
AU2329097A (en) 1997-10-17
CA2249212A1 (en) 1997-10-02
FI981916A7 (fi) 1998-09-08
OA10885A (en) 2003-02-18
EP0906120A1 (de) 1999-04-07
US5846931A (en) 1998-12-08
EP0906120B1 (de) 2002-06-26
FI981916A0 (fi) 1998-09-08
JP2000507944A (ja) 2000-06-27
DE69713597T2 (de) 2003-02-20
KR19990087489A (ko) 1999-12-27
AU727312B2 (en) 2000-12-07
FI981916L (fi) 1998-09-08

Similar Documents

Publication Publication Date Title
NO984345D0 (no) FremgangsmÕte for vevsinduksjon ved anvendelse av en kombinasjon av benmorfogenisk protein og paratyroid hormon-relatert peptid
Sampath et al. Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily.
Noshi et al. Recombinant human bone morphogenetic protein‐2 potentiates the in vivo osteogenic ability of marrow/hydroxyapatite composites
JP2522568B2 (ja) 骨形成デバイス
DK1400252T3 (da) Fremgangsmåde og sammensætninger til heling og reparation af ledbrusk
DK0831884T3 (da) Anvendelse af knoglemorfogenetiske proteiner til heling og reparation af bindevævsbinding
ATE218579T1 (de) Zusammensetzungen und methoden zur behandlung von infektionen unter verwendung von indolicidin- analogen
DK0968012T3 (da) Osteogene indretninger og fremgangsmåder til anvendelse deraf til reparation af knogler
WO1998033509A3 (en) Useful properties of human lactoferrin and variants thereof
Lane Bone morphogenic protein science and studies
CA2030518A1 (en) Osteoinductive compositions
RU98120477A (ru) Способы переноса генов для заживления ран
NZ332926A (en) Immunogenic non-naturally occurring peptides and molecules based on somatostatin that modulate the activity of hormones or their receptors peptides, antibodies, vaccines and uses thereof
DE69129865D1 (de) Osteogene peptide
BR9406715A (pt) Molécula de DNA isolada célula hospedeira vetor método para produzir uma proteina (BMP-11) polipeptideo de proteina-11 morfogenética de osso purificada (BMP-11) e molécula de DNA quimérica
ES2166371T3 (es) Celulas de levadura tratadas para producir sustitutos de proteinas de sistemas de feromonas y usos de las mismas.
ATE333464T1 (de) Zusammensetzungen und verfahren zur behandlung von infektionen unter verwendung von kationischen peptiden allein oder in kombination mit antibiotika
WO1995016035A3 (en) Bmp-12, bmp-13 and tendon-inducing compositions thereof
GEP20033095B (en) Parathyroid Hormone Analogues for the Treatment of Osteoporosis
GB9606040D0 (en) Active peptide
WO2003092468A3 (en) Biomatrix structural containment and fixation systems and methods of use thereof
ATE255920T1 (de) Methoden und zusammensetzungen zur heilung und reparatur von gelenkknorpeln
IL115381A (en) Polypeptide compounds containing D-2-alkyltryptophan capable of promoting the release of growth hormone
PT1117689E (pt) Antagonista de proteína morfogenética do osso baseada na proteína madura
Yoshimura et al. Purification of water-soluble bone-inductive protein from bovine demineralized bone matrix

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application