NO984380L - Nye piperazin og piperidinforbindelser - Google Patents

Nye piperazin og piperidinforbindelser

Info

Publication number
NO984380L
NO984380L NO984380A NO984380A NO984380L NO 984380 L NO984380 L NO 984380L NO 984380 A NO984380 A NO 984380A NO 984380 A NO984380 A NO 984380A NO 984380 L NO984380 L NO 984380L
Authority
NO
Norway
Prior art keywords
piperidine compounds
new piperazine
piperazine
new
piperidine
Prior art date
Application number
NO984380A
Other languages
English (en)
Other versions
NO312835B1 (no
NO984380D0 (no
Inventor
Roelof W Feenstra
Jacobus A J Den Hartog
Cornelis G Kruse
Martinus T M Tulp
Stephen K Long
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of NO984380D0 publication Critical patent/NO984380D0/no
Publication of NO984380L publication Critical patent/NO984380L/no
Publication of NO312835B1 publication Critical patent/NO312835B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
NO19984380A 1997-09-24 1998-09-21 Nye piperizin- og piperidinforbindelser, fremgangsmåte for fremstilling derav, anvendelse derav, farmasöytisk sammensetningog fremstilling av denne NO312835B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97202950 1997-09-24

Publications (3)

Publication Number Publication Date
NO984380D0 NO984380D0 (no) 1998-09-21
NO984380L true NO984380L (no) 1999-03-25
NO312835B1 NO312835B1 (no) 2002-07-08

Family

ID=8228755

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984380A NO312835B1 (no) 1997-09-24 1998-09-21 Nye piperizin- og piperidinforbindelser, fremgangsmåte for fremstilling derav, anvendelse derav, farmasöytisk sammensetningog fremstilling av denne

Country Status (30)

Country Link
US (2) US6090812A (no)
EP (1) EP0908458B1 (no)
JP (1) JP4191826B2 (no)
KR (1) KR100632188B1 (no)
CN (1) CN1093857C (no)
AR (1) AR017127A1 (no)
AT (1) ATE316529T1 (no)
AU (1) AU733526B2 (no)
BR (1) BR9803497A (no)
CA (1) CA2247734C (no)
CY (1) CY1107494T1 (no)
CZ (1) CZ296741B6 (no)
DE (1) DE69833297T2 (no)
DK (1) DK0908458T3 (no)
DZ (1) DZ2613A1 (no)
ES (1) ES2255127T3 (no)
HU (1) HU227422B1 (no)
ID (1) ID20895A (no)
IL (1) IL126295A (no)
NO (1) NO312835B1 (no)
NZ (1) NZ331984A (no)
PL (1) PL190622B1 (no)
PT (1) PT908458E (no)
RU (1) RU2197488C2 (no)
SI (1) SI0908458T1 (no)
SK (1) SK285205B6 (no)
TR (1) TR199801866A1 (no)
TW (1) TW530054B (no)
UA (1) UA66756C2 (no)
ZA (1) ZA988749B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200994B1 (en) 1999-01-07 2001-03-13 American Home Products Corp 1,4-Disubstituted cyclohexane derivatives for the treatment of depression
ATE223406T1 (de) * 1999-01-07 2002-09-15 Wyeth Corp 1,4-disubstitutierte cyclohexanderivate zur behandlung von depression
DE10005150A1 (de) * 2000-02-07 2001-08-09 Merck Patent Gmbh Verfahren zur Herstellung von 5-Arylnicotinaldehyden
US6911448B2 (en) * 2000-05-12 2005-06-28 Solvay Pharmaceuticals B.V. Piperazine and piperidine compounds
DE10115922A1 (de) * 2001-03-30 2002-10-10 Bayer Ag Cyclisch substituierte 2-Thio-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung
US7504395B2 (en) * 2001-07-20 2009-03-17 Psychogenics, Inc. Treatment for attention-deficit hyperactivity disorder
US7435738B2 (en) 2003-08-18 2008-10-14 Solvay Pharmaceuticals, Inc. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
US7405216B2 (en) 2004-08-18 2008-07-29 Solvay Pharmaceuticals, B.V. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
US7423040B2 (en) 2005-02-18 2008-09-09 Irene Eijgendaal Stable crystalline form of bifeprunox mesylate, dosage forms thereof and methods for using same
US7964604B2 (en) 2005-02-18 2011-06-21 Solvay Pharmaceuticals B.V. Bifeprunox mesylate maintenance dose compositions and methods for using the same
AU2007247251B2 (en) 2006-05-02 2011-11-03 Solvay Pharmaceuticals B.V. N-oxides of pyridylmethylpiperazine and -piperidine derivatives
US20070275977A1 (en) * 2006-05-02 2007-11-29 Van Aar Marcel P N-oxides of pyridylmethyl -piperazine and -piperidine derivatives
US7786126B2 (en) 2006-06-16 2010-08-31 Solvay Pharmaceuticals B.V. Combination preparations comprising SLV308 and a dopamine agonist
US8106056B2 (en) 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
WO2011088838A1 (en) 2010-01-25 2011-07-28 H. Lundbeck A/S Novel 6,6a,7,8,9,10-hexahydro-4h-4,8,10a-triaza-acephenanthrylene derivatives as dopamine d2 ligands
US8877778B2 (en) * 2010-12-15 2014-11-04 Hoffmann-La Roche Inc. Benzofurane compounds
US8921397B2 (en) 2011-05-04 2014-12-30 Hoffmann-La Roche Inc. Benzofurane-piperidine compounds
JP7030776B2 (ja) 2016-07-20 2022-03-07 ノバルティス アーゲー アミノピリジン誘導体およびそれらの選択的ａｌｋ－２阻害剤としての使用
KR101665971B1 (ko) 2016-08-10 2016-10-13 (주)글로벌 로보틱스 차량용 발포패드 부착장치
BR112022009710A2 (pt) 2019-11-22 2022-08-09 Incyte Corp Terapia de combinação compreendendo um inibidor de alk2 e um inibidor de jak2
CA3187767A1 (en) 2020-06-16 2021-12-23 Incyte Corporation Alk2 inhibitors for the treatment of anemia

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190472B1 (en) * 1984-12-21 1989-07-12 Duphar International Research B.V New pharmaceutical compositions having anti-psychotic properties
DE3586794T2 (de) 1984-12-21 1993-05-27 Duphar Int Res Arzneimittel mit psychotroper wirkung.
DK93087A (da) * 1986-02-27 1987-08-28 Duphar Int Res Hidtil ukendte aryl substituerede (n-piperidinyl)methyl- og (n-piperazinyl)methylazoler med antipsykotiske egenskaber
EP0508347A1 (en) * 1991-04-10 1992-10-14 Hoechst Aktiengesellschaft 5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl)) piperidinyl]-4H-1-benzopyran-4-one, its preparation and its use
NZ240863A (en) * 1991-09-11 1995-04-27 Mcneilab Inc Substituted 4-aryl piperidine and 4-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof
JPH05262765A (ja) * 1992-03-18 1993-10-12 Sumitomo Chem Co Ltd ベンゾフラン誘導体およびそれを有効成分とする除草剤
FR2692264B1 (fr) 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
US5332732A (en) * 1992-09-11 1994-07-26 Mcneilab, Inc. Thiophene and pyridine antipsychotic agents
US5436246A (en) * 1992-09-17 1995-07-25 Merrell Dow Pharmaceuticals Inc. Serotonin receptor agents
RU2118322C1 (ru) * 1993-07-05 1998-08-27 Дюфар Интернэшнл Рисерч Б.В. 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
EP0650964A1 (en) 1993-11-02 1995-05-03 Duphar International Research B.V 1 2H-1-benzopyran-2-one-8-yl -piperazine derivatives
DE4425146A1 (de) 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen
US5607936A (en) * 1994-09-30 1997-03-04 Merck & Co., Inc. Substituted aryl piperazines as neurokinin antagonists
DE69615376T2 (de) * 1995-07-13 2002-09-05 Knoll Gmbh Piperazin-derivate als heilmittel
AU708053B2 (en) * 1996-03-29 1999-07-29 Duphar International Research B.V. Piperazine and piperidine compounds
DE19637237A1 (de) * 1996-09-13 1998-03-19 Merck Patent Gmbh Piperazin-Derivate

Also Published As

Publication number Publication date
HU227422B1 (en) 2011-05-30
CN1220265A (zh) 1999-06-23
AU733526B2 (en) 2001-05-17
DE69833297T2 (de) 2006-07-20
ATE316529T1 (de) 2006-02-15
TR199801866A1 (xx) 1999-04-21
AU8607998A (en) 1999-04-15
IL126295A (en) 2003-02-12
NO312835B1 (no) 2002-07-08
SI0908458T1 (sl) 2006-06-30
AR017127A1 (es) 2001-08-22
BR9803497A (pt) 2000-05-02
JPH11302279A (ja) 1999-11-02
KR100632188B1 (ko) 2007-04-25
PL190622B1 (pl) 2005-12-30
DE69833297D1 (de) 2006-04-13
ES2255127T3 (es) 2006-06-16
IL126295A0 (en) 1999-05-09
CA2247734A1 (en) 1999-03-24
ZA988749B (en) 1999-03-26
KR19990029982A (ko) 1999-04-26
PL328754A1 (en) 1999-03-29
CA2247734C (en) 2007-08-07
NO984380D0 (no) 1998-09-21
US6090812A (en) 2000-07-18
PT908458E (pt) 2006-05-31
UA66756C2 (uk) 2004-06-15
EP0908458B1 (en) 2006-01-25
NZ331984A (en) 2000-02-28
JP4191826B2 (ja) 2008-12-03
CN1093857C (zh) 2002-11-06
HK1018272A1 (en) 1999-12-17
CZ303098A3 (cs) 1999-04-14
DZ2613A1 (fr) 2003-03-01
SK285205B6 (sk) 2006-08-03
CZ296741B6 (cs) 2006-06-14
SK129498A3 (en) 1999-04-13
DK0908458T3 (da) 2006-06-06
HU9802129D0 (en) 1998-11-30
HUP9802129A1 (hu) 2000-03-28
TW530054B (en) 2003-05-01
CY1107494T1 (el) 2013-03-13
RU2197488C2 (ru) 2003-01-27
ID20895A (id) 1999-03-25
EP0908458A1 (en) 1999-04-14
USRE41425E1 (en) 2010-07-06

Similar Documents

Publication Publication Date Title
NO20012339L (no) Nye piperazin- og piperidinforbindelser
NO984380D0 (no) Nye piperazin og piperidin forbindelser
NO942977D0 (no) Piperazin og piperidinderivater og anvendelse derav som antipsykotiske midler
NO20023787L (no) Piperazin- og piperidinderivater
NO20000226L (no) Nye spiroazabicykliske heterocykliske forbindelser
FI945808A7 (fi) Dimeeriset piperidiini-, tetrahydropyridiini- ja piperatsiinijohdannaiset
TR199600438A2 (tr) Piperazin türevleri.
FI942252A7 (fi) Piperatsiinijohdannaisia
NO20000216D0 (no) Piperazinderivater
FI964815L (fi) Piperatsiinijohdoksia 5-HT1A antagonisteina
NO972937D0 (no) Farmasöytiske piperazinforbindelser
DE60101386D1 (de) Piperazin- und piperidinverbindungen
NO974605L (no) Nye heterosykliske forbindelser
ATE321042T1 (de) Piperazin-derivate
EE200100498A (et) 1,4-asendatud piperasiin-, 1,4-asendatud piperidiin- ja 1-asendatud 4-alkülidenüülpiperidiinühendidning nende raviotstarbeline kasutamine
FI945086A0 (fi) 1-(2H-1-bentsopyran-2-oni-8-yyli)piperatsiinijohdannaisia
FI973164A0 (fi) Antipsykoottisia 4-(1H-indolyl-1-yyli)-1-substituoituja piperidiinijohdannaisia
NO20003601D0 (no) Nye naftyl-substituerte og anilid-substituerte sulfonamider
FR2758327B1 (fr) Nouvelles arylpiperazines derivees de piperidine
DK0937458T3 (da) Pyrrolidin- og piperidinderivater
NO20003128D0 (no) Nye p-aminofenylderivater og deres anvendelse
NO954913D0 (no) Nye heterocykliske amider
PT1131308E (pt) Novos compostos de piperazina e piperidina
NO995430D0 (no) Nye heterosykliske forbindelser
DK0886645T3 (da) Nye 19-nor-pregnen-derivater

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees