NO993122L - Nye nitroforbindelser, fremgangsmåte ved deres frelmstilling og farmasoeytiske sammensetninger innehodende dem - Google Patents

Nye nitroforbindelser, fremgangsmåte ved deres frelmstilling og farmasoeytiske sammensetninger innehodende dem

Info

Publication number
NO993122L
NO993122L NO993122A NO993122A NO993122L NO 993122 L NO993122 L NO 993122L NO 993122 A NO993122 A NO 993122A NO 993122 A NO993122 A NO 993122A NO 993122 L NO993122 L NO 993122L
Authority
NO
Norway
Prior art keywords
preparation
methods
pharmaceutical compositions
compositions containing
nitro compounds
Prior art date
Application number
NO993122A
Other languages
English (en)
Other versions
NO993122D0 (no
NO312722B1 (no
Inventor
Solo Goldstein
Alain Dhainaut
Andre Tizot
Brian Lockhart
Pierre Lestage
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of NO993122D0 publication Critical patent/NO993122D0/no
Publication of NO993122L publication Critical patent/NO993122L/no
Publication of NO312722B1 publication Critical patent/NO312722B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19993122A 1998-06-26 1999-06-23 Nye nitrogenforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem NO312722B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9808116A FR2780404B1 (fr) 1998-06-26 1998-06-26 Nouveaux derives de nitrone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
NO993122D0 NO993122D0 (no) 1999-06-23
NO993122L true NO993122L (no) 1999-12-27
NO312722B1 NO312722B1 (no) 2002-06-24

Family

ID=9527896

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993122A NO312722B1 (no) 1998-06-26 1999-06-23 Nye nitrogenforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem

Country Status (17)

Country Link
US (1) US6034250A (no)
EP (1) EP0967207B1 (no)
JP (1) JP2000026428A (no)
CN (1) CN1153766C (no)
AT (1) ATE223904T1 (no)
AU (1) AU747203B2 (no)
BR (1) BR9903282A (no)
CA (1) CA2274621C (no)
DE (1) DE69902851T2 (no)
DK (1) DK0967207T3 (no)
ES (1) ES2183492T3 (no)
FR (1) FR2780404B1 (no)
HU (1) HUP9902199A1 (no)
NO (1) NO312722B1 (no)
NZ (1) NZ336460A (no)
PT (1) PT967207E (no)
ZA (1) ZA994201B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096899A (en) * 1998-04-14 2000-08-01 The Regents Of The University Of Michigan Cylic imidazole compounds having relatively low hydrogen content and relatively high nitrogen content and polymers formed therefrom
WO2002064169A1 (en) * 2001-02-16 2002-08-22 Daiichi Suntory Pharma Co., Ltd. Methods of treating diseases in association with decrease in the expression of aop-1 gene or aop-1 and remedies for the diseases
WO2003010154A1 (en) * 2001-07-26 2003-02-06 Samsung Electronics Co. Ltd. Seleno compounds containing nitrone moiety, their preparation and their therapeutic uses
EP1482931B1 (en) 2002-03-05 2011-10-19 TransTech Pharma, Inc. Mono- and bicyclic azole derivatives that inhibit the interaction of ligands with rage
CA2480227A1 (en) * 2002-03-28 2003-10-09 Oxis International, Inc. Neuroprotectant methods, compositions, and screening methods thereof
CN1805743A (zh) * 2003-05-20 2006-07-19 特兰斯泰克制药公司 用作逆转淀粉样变性及其他与之相关疾病的rage拮抗剂
CN101468970B (zh) * 2008-04-25 2011-05-11 暨南大学 一种硝酮类化合物及其制备方法和在制药中的应用
CA2772797C (en) 2009-09-30 2018-09-25 Transtech Pharma, Inc. Substituted imidazole derivatives
JP5885620B2 (ja) * 2012-08-22 2016-03-15 四国化成工業株式会社 2−(2−フリル)イミダゾール化合物及び酸化防止剤
FR3012451B1 (fr) 2013-10-25 2016-11-11 Michelin & Cie Compose 1,3-dipolaire portant une fonction imidazole
FR3012460B1 (fr) 2013-10-25 2015-12-11 Michelin & Cie Composition de caoutchouc comprenant un elastomere dienique portant des fonctions imidazole reparties de facon aleatoire le long de la chaine
FR3012458B1 (fr) * 2013-10-25 2015-10-30 Michelin & Cie Composition de caoutchouc comprenant un additif compose 1,3-dipolaire portant une fonction imidazole

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0643403B2 (ja) * 1986-01-25 1994-06-08 四国化成工業株式会社 イミダゾール―アルドキシム化合物の合成方法
US4803282A (en) * 1986-08-27 1989-02-07 Pennwalt Corporation Alpha-substituted ketonitrone derivatives
EP0590072B1 (en) * 1991-06-18 2001-12-05 Oklahoma Medical Research Foundation Use of spin trapping for the treatment of diseases associated with oxidation of lipids and proteins
US5455272A (en) * 1993-10-22 1995-10-03 Oklahoma Medical Research Foundation Spin trap nitronyl hindered phenols
WO1997019054A1 (en) * 1995-11-17 1997-05-29 Florida International University Azulenyl nitrone spin trapping agents, methods of making and using same

Also Published As

Publication number Publication date
ES2183492T3 (es) 2003-03-16
US6034250A (en) 2000-03-07
DE69902851D1 (de) 2002-10-17
FR2780404B1 (fr) 2001-04-13
HU9902199D0 (en) 1999-08-30
EP0967207A1 (fr) 1999-12-29
CN1245169A (zh) 2000-02-23
HUP9902199A1 (hu) 2000-06-28
EP0967207B1 (fr) 2002-09-11
PT967207E (pt) 2002-12-31
ATE223904T1 (de) 2002-09-15
CN1153766C (zh) 2004-06-16
CA2274621C (fr) 2004-01-20
ZA994201B (en) 2000-01-11
NO993122D0 (no) 1999-06-23
NZ336460A (en) 2000-05-26
CA2274621A1 (fr) 1999-12-26
DK0967207T3 (da) 2003-01-20
AU3680099A (en) 2000-01-13
BR9903282A (pt) 2000-04-18
AU747203B2 (en) 2002-05-09
JP2000026428A (ja) 2000-01-25
DE69902851T2 (de) 2003-05-28
FR2780404A1 (fr) 1999-12-31
NO312722B1 (no) 2002-06-24

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