NO993301L - Ftalazinoner - Google Patents
FtalazinonerInfo
- Publication number
- NO993301L NO993301L NO993301A NO993301A NO993301L NO 993301 L NO993301 L NO 993301L NO 993301 A NO993301 A NO 993301A NO 993301 A NO993301 A NO 993301A NO 993301 L NO993301 L NO 993301L
- Authority
- NO
- Norway
- Prior art keywords
- pct
- date jul
- sec
- pub
- phthalazinones
- Prior art date
Links
- 101000909851 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) cAMP/cGMP dual specificity phosphodiesterase Rv0805 Proteins 0.000 abstract 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Lubricants (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97100488 | 1997-01-15 | ||
| PCT/EP1998/000124 WO1998031674A1 (en) | 1997-01-15 | 1998-01-12 | Phthalazinones |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO993301D0 NO993301D0 (no) | 1999-07-02 |
| NO993301L true NO993301L (no) | 1999-09-10 |
| NO313137B1 NO313137B1 (no) | 2002-08-19 |
Family
ID=8226366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19993301A NO313137B1 (no) | 1997-01-15 | 1999-07-02 | Ftalazinoner |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6103718A (no) |
| EP (1) | EP0971901B1 (no) |
| JP (1) | JP2001508078A (no) |
| KR (1) | KR20000070150A (no) |
| CN (1) | CN1127487C (no) |
| AT (1) | ATE233247T1 (no) |
| AU (1) | AU735934B2 (no) |
| BR (1) | BR9806752A (no) |
| CA (1) | CA2276455C (no) |
| CY (1) | CY2446B1 (no) |
| CZ (1) | CZ293815B6 (no) |
| DE (1) | DE69811645T2 (no) |
| DK (1) | DK0971901T3 (no) |
| EA (1) | EA002764B1 (no) |
| EE (1) | EE03968B1 (no) |
| ES (1) | ES2193508T3 (no) |
| HU (1) | HUP0001541A3 (no) |
| IL (1) | IL130659A (no) |
| NO (1) | NO313137B1 (no) |
| NZ (1) | NZ336573A (no) |
| PL (1) | PL189418B1 (no) |
| PT (1) | PT971901E (no) |
| SI (1) | SI0971901T1 (no) |
| SK (1) | SK283270B6 (no) |
| TR (1) | TR199901653T2 (no) |
| WO (1) | WO1998031674A1 (no) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1070056T3 (da) * | 1998-03-14 | 2004-11-08 | Altana Pharma Ag | Phthalazinon-PDE III/IV-inhibitorer |
| CA2715683A1 (en) | 1999-08-21 | 2001-03-01 | Nycomed Gmbh | Synergistic combination |
| WO2001019818A1 (en) * | 1999-09-14 | 2001-03-22 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phthalazinone derivatives as pd3/4 inhibitors |
| EP1228046B1 (en) | 1999-10-25 | 2007-09-26 | Nycomed GmbH | Phthalazinone derivatives as pde 4 inhibitors |
| HUP0203487A2 (hu) | 1999-10-25 | 2003-02-28 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrahidrotiopirán-ftalazinon-származékok, mint PDE4-inhibitorok és ezeket tartalmazó gyógyszerkészítmények |
| CZ20023997A3 (cs) | 2000-06-05 | 2003-05-14 | Altana Pharma Ag | Pyridazinonové deriváty |
| US7868015B2 (en) * | 2000-08-10 | 2011-01-11 | Cold Spring Harbor Laboratory | Phosphodiesesterase 4 inhibitors for the treatment of a cognitive deficit |
| US20040224316A1 (en) * | 2000-08-10 | 2004-11-11 | Tully Timothy P. | Augmented cognitive training |
| HRP20030636B1 (en) | 2001-02-15 | 2012-05-31 | Nycomed Gmbh | Phthalayinone-piperidino-derivatives as pde4 inhibitors |
| EE200300514A (et) * | 2001-04-25 | 2004-02-16 | Altana Pharma Ag | Ftalasinoonid, nende kasutamine hingamisteede haigusnähte leevendavate ravimite valmistamiseks ningneid sisaldavad ravimid |
| JP4021329B2 (ja) * | 2001-04-25 | 2007-12-12 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | ピペラジノ誘導体およびｐｄｅ４阻害剤としてのその使用 |
| US7402580B2 (en) | 2002-02-19 | 2008-07-22 | Ono Pharmaceutical Co., Ltd. | Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient |
| WO2004018449A1 (en) * | 2002-08-10 | 2004-03-04 | Altana Pharma Ag | Piperidine-derivatives as pde4 inhibitors |
| CA2494650A1 (en) * | 2002-08-10 | 2004-03-04 | Altana Pharma Ag | Pyridazinone-derivatives as pde4 inhibitors |
| HRP20050197A2 (en) * | 2002-08-10 | 2006-06-30 | Altana Pharma Ag | Piperidine-n-oxide-derivatives |
| JP2005538140A (ja) * | 2002-08-10 | 2005-12-15 | アルタナ ファルマ アクチエンゲゼルシャフト | Ｐｄｅ４インヒビターとしてのピペリジン−ピリダゾン及びフタラゾン |
| EA200501548A1 (ru) | 2003-04-01 | 2006-02-24 | Апплайд Резеч Системз Арс Холдинг Н.В. | Ингибиторы фосфодиэстераз при бесплодии |
| WO2004098633A1 (en) * | 2003-05-12 | 2004-11-18 | Altana Pharma Ag | Composition comprising a pde-4 inhibitor and a tnf alpha antagonist |
| JP4591349B2 (ja) * | 2003-07-14 | 2010-12-01 | 宇部興産株式会社 | ４−アミノテトラヒドロピラン化合物及びその酸塩の製法、その合成中間体およびその製法 |
| AU2005210042B2 (en) * | 2004-02-04 | 2011-04-21 | Takeda Gmbh | 2-(piperidin-4-yl) -4, 5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors |
| US20080227790A1 (en) * | 2004-02-04 | 2008-09-18 | Altana Pharma Ag | Pyridazinone Derivatives and their Use as Pde4 Inhibitors |
| CN101163681A (zh) * | 2005-04-21 | 2008-04-16 | 日本新药株式会社 | 2,3-二氮杂萘酮衍生物及其医药品 |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| US7985756B2 (en) | 2005-10-21 | 2011-07-26 | Braincells Inc. | Modulation of neurogenesis by PDE inhibition |
| WO2007053596A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007134136A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| WO2007134077A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| EP2068872A1 (en) | 2006-09-08 | 2009-06-17 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| SI2148876T1 (sl) | 2007-05-16 | 2012-01-31 | Nycomed Gmbh | Pirazolonski derivati kot PDE4 inhibitorji |
| AR074318A1 (es) * | 2008-11-14 | 2011-01-05 | Nycomed Gmbh | Derivados heterociclicos de pirazolona, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de enfermedades de las vias respiratorias. |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| EP2721030B1 (en) * | 2011-06-17 | 2015-12-16 | Takeda GmbH | Novel phthalazinone-pyrrolopyrimidinecarboxamide derivatives |
| EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| CN105307655B (zh) | 2013-03-13 | 2019-05-03 | 弗拉特利发现实验室有限责任公司 | 哒嗪酮化合物及其用于制备治疗囊肿状纤维化的药物的应用 |
| US20150050626A1 (en) * | 2013-03-15 | 2015-02-19 | Dart Neuroscience, Llc | Systems, Methods, and Software for Improving Cognitive and Motor Abilities |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2845456A1 (de) * | 1978-10-19 | 1980-08-14 | Merck Patent Gmbh | 6-arylpyridazin-3-one und verfahren zu ihrer herstellung |
| BR9307570A (pt) * | 1992-12-02 | 1999-05-25 | Pfizer | Diéteres de catecol como inibidores seletivos de pdeiv |
| EP0634404A1 (en) * | 1993-07-13 | 1995-01-18 | Rhone Poulenc Agriculture Ltd. | Phtalazin derivatives and their use as pesticides |
| CA2173493C (en) * | 1994-08-09 | 2008-03-25 | Nobuhisa Watanabe | Fused pyridazine compounds |
-
1998
- 1998-01-12 ES ES98901959T patent/ES2193508T3/es not_active Expired - Lifetime
- 1998-01-12 EE EEP199900274A patent/EE03968B1/xx not_active IP Right Cessation
- 1998-01-12 SK SK951-99A patent/SK283270B6/sk unknown
- 1998-01-12 PT PT98901959T patent/PT971901E/pt unknown
- 1998-01-12 DE DE69811645T patent/DE69811645T2/de not_active Expired - Fee Related
- 1998-01-12 BR BR9806752-4A patent/BR9806752A/pt active Search and Examination
- 1998-01-12 EP EP98901959A patent/EP0971901B1/en not_active Expired - Lifetime
- 1998-01-12 CA CA002276455A patent/CA2276455C/en not_active Expired - Fee Related
- 1998-01-12 DK DK98901959T patent/DK0971901T3/da active
- 1998-01-12 PL PL98334561A patent/PL189418B1/pl not_active IP Right Cessation
- 1998-01-12 TR TR1999/01653T patent/TR199901653T2/xx unknown
- 1998-01-12 NZ NZ336573A patent/NZ336573A/xx unknown
- 1998-01-12 JP JP53363598A patent/JP2001508078A/ja not_active Ceased
- 1998-01-12 EA EA199900620A patent/EA002764B1/ru not_active IP Right Cessation
- 1998-01-12 HU HU0001541A patent/HUP0001541A3/hu unknown
- 1998-01-12 WO PCT/EP1998/000124 patent/WO1998031674A1/en not_active Ceased
- 1998-01-12 AT AT98901959T patent/ATE233247T1/de not_active IP Right Cessation
- 1998-01-12 AU AU58629/98A patent/AU735934B2/en not_active Ceased
- 1998-01-12 KR KR1019997006376A patent/KR20000070150A/ko not_active Ceased
- 1998-01-12 CN CN98803169A patent/CN1127487C/zh not_active Expired - Fee Related
- 1998-01-12 IL IL13065998A patent/IL130659A/en not_active IP Right Cessation
- 1998-01-12 US US09/341,135 patent/US6103718A/en not_active Expired - Fee Related
- 1998-01-12 SI SI9830396T patent/SI0971901T1/xx unknown
- 1998-01-12 CZ CZ19992533A patent/CZ293815B6/cs not_active IP Right Cessation
-
1999
- 1999-07-02 NO NO19993301A patent/NO313137B1/no unknown
-
2004
- 2004-08-11 CY CY0400064A patent/CY2446B1/xx unknown
Also Published As
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