NO994110L - Fremgangsmaate ved fremstilling av stabile, ikke-hygroskopiske salter av L(-)-carnitin - Google Patents
Fremgangsmaate ved fremstilling av stabile, ikke-hygroskopiske salter av L(-)-carnitinInfo
- Publication number
- NO994110L NO994110L NO994110A NO994110A NO994110L NO 994110 L NO994110 L NO 994110L NO 994110 A NO994110 A NO 994110A NO 994110 A NO994110 A NO 994110A NO 994110 L NO994110 L NO 994110L
- Authority
- NO
- Norway
- Prior art keywords
- carnitine
- stable
- preparation
- hygroscopic salts
- salts
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 4
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical class C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002002 slurry Substances 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/285—Polyhydroxy dicarboxylic acids having five or more carbon atoms, e.g. saccharic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI000409A IT1289974B1 (it) | 1997-02-25 | 1997-02-25 | Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine |
| PCT/EP1998/001039 WO1998038157A1 (fr) | 1997-02-25 | 1998-02-24 | Procede pour la preparation de sels non hygroscopiques stables de l (-)carnitine et d'alcanoyle l (-)carnitines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO994110D0 NO994110D0 (no) | 1999-08-25 |
| NO994110L true NO994110L (no) | 1999-08-25 |
Family
ID=11376175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO994110A NO994110L (no) | 1997-02-25 | 1999-08-25 | Fremgangsmaate ved fremstilling av stabile, ikke-hygroskopiske salter av L(-)-carnitin |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6271258B1 (fr) |
| EP (1) | EP1019362B1 (fr) |
| JP (1) | JP2001513096A (fr) |
| KR (1) | KR100538788B1 (fr) |
| CN (1) | CN1248967A (fr) |
| AT (1) | ATE222233T1 (fr) |
| AU (1) | AU724276B2 (fr) |
| BR (1) | BR9807761A (fr) |
| CA (1) | CA2281630C (fr) |
| CZ (1) | CZ290893B6 (fr) |
| DE (1) | DE69807245T2 (fr) |
| DK (1) | DK1019362T3 (fr) |
| EE (1) | EE03561B1 (fr) |
| ES (1) | ES2182290T3 (fr) |
| HU (1) | HUP0001674A3 (fr) |
| IL (1) | IL131256A (fr) |
| IS (1) | IS5160A (fr) |
| IT (1) | IT1289974B1 (fr) |
| NO (1) | NO994110L (fr) |
| NZ (1) | NZ337188A (fr) |
| PL (1) | PL188762B1 (fr) |
| PT (1) | PT1019362E (fr) |
| SK (1) | SK115399A3 (fr) |
| TR (1) | TR199902043T2 (fr) |
| WO (1) | WO1998038157A1 (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1312018B1 (it) * | 1999-03-19 | 2002-04-04 | Fassi Aldo | Procedimento migliorato per la produzione di sali non igroscopicidella l(-)-carnitina. |
| KR100461572B1 (ko) * | 1999-03-27 | 2004-12-14 | 삼성정밀화학 주식회사 | L-카르니틴 칼슘 염과 이의 제조방법 |
| CA2383814C (fr) * | 1999-09-03 | 2010-08-17 | Sigma-Tau Healthscience S.P.A. | L-carnitine ultrafine, procedes de preparation associes, compositions contenant cette derniere et procedes d'utilisation associes |
| IT1316988B1 (it) * | 2000-02-10 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Procedimento migliorato di preparazione industriale di mucati dellal-carnitina e di alcanoil l-carnitine. |
| IT1317013B1 (it) * | 2000-04-12 | 2003-05-26 | Biosalts Srl | Sostanze dolcificanti, particolarmente per il caffe' ed il the'. |
| ITRM20020055A1 (it) * | 2002-02-04 | 2003-08-04 | Aldo Fassi | Sali metallici di carnitine, integratori dietetici/nutritivi che li contengono e kit dietetici per contrastare disturbi sessuali in soggetti |
| AU2006265280B2 (en) * | 2005-07-05 | 2011-07-14 | Lonza Ag | Spray-drying process for producing a dry carnitine powder or granulate |
| US7523176B2 (en) * | 2005-08-02 | 2009-04-21 | International Business Machines Corporation | Method, apparatus, and computer program product for reconfiguring a storage area network to support the execution of an application automatically upon execution of the application |
| CA2637806A1 (fr) * | 2005-11-07 | 2007-05-18 | Russell M. Jaffe | Compositions pour reguler des troubles metaboliques et procedes d'utilisation de celles-ci |
| CN101209975B (zh) * | 2006-12-29 | 2010-12-01 | 沈阳科硕营养科技有限公司 | 左旋肉碱富马酸钙及其制备方法与用途 |
| JP2011068563A (ja) * | 2008-09-09 | 2011-04-07 | Mitsubishi Rayon Co Ltd | カルニチンフマル酸塩及びその製造方法 |
| KR101291186B1 (ko) * | 2010-07-23 | 2013-09-13 | 주식회사 셀트리온제약 | L-카르니틴 1,5-나프탈렌다이설폰산염 및 이를 포함하는 약제학적 조성물 |
| EP2425834A1 (fr) * | 2010-09-06 | 2012-03-07 | Lonza Ltd. | Procédé pour la production de tartrate L-carnitine |
| CN108383741A (zh) * | 2018-03-16 | 2018-08-10 | 开原亨泰化工有限公司 | 一种制备左旋肉碱成盐的新方法 |
| CN118638020B (zh) * | 2024-08-08 | 2024-11-19 | 杭州海尔希畜牧科技有限公司 | L-天门冬氨酸l(-)肉碱(1:1)的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1230610A (fr) * | 1983-11-02 | 1987-12-22 | Vincenzo Iannella | Procede de preparation d'hydrochlorure de l(-)carnitine et de sel de l(-)carnitine |
| EP0150688B1 (fr) * | 1983-12-28 | 1987-04-22 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Sels de L-carnitine et d'alcanoyl L-carnitines et procédé pour leur préparation |
| US5073376A (en) * | 1989-12-22 | 1991-12-17 | Lonza Ltd. | Preparations containing l-carnitine |
| DE4111913A1 (de) * | 1991-04-12 | 1992-10-15 | Degussa | Verfahren zur herstellung von l-carnitin aus d,l-carnitinnitrilsalzen |
| CH682485A5 (de) * | 1991-08-13 | 1993-09-30 | Lonza Ag | Verfahren zur Herstellung optisch aktiver Carbonsäuren durch Racematspaltung. |
| TW397686B (en) * | 1993-08-11 | 2000-07-11 | Takeda Chemical Industries Ltd | Antacid compositions and pharmaceutical compositions |
| IT1272290B (it) * | 1994-06-20 | 1997-06-16 | Avantgarde Spa | Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee |
| IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
| DE69704561T2 (de) * | 1996-05-31 | 2001-08-09 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A., Rom/Roma | Stabile nicht-hygroskopische salze von l(-)carnitin und alkanoyl-l(-)carnitinen,ein verfahren zu deren herstellung und feste, oral verabreichbare zusammensetzungen, die solche salze enthalten |
-
1997
- 1997-02-25 IT IT97MI000409A patent/IT1289974B1/it active IP Right Grant
-
1998
- 1998-02-24 KR KR10-1999-7007778A patent/KR100538788B1/ko not_active Expired - Fee Related
- 1998-02-24 EP EP98913582A patent/EP1019362B1/fr not_active Expired - Lifetime
- 1998-02-24 CZ CZ19993028A patent/CZ290893B6/cs not_active IP Right Cessation
- 1998-02-24 US US09/355,804 patent/US6271258B1/en not_active Expired - Fee Related
- 1998-02-24 SK SK1153-99A patent/SK115399A3/sk unknown
- 1998-02-24 ES ES98913582T patent/ES2182290T3/es not_active Expired - Lifetime
- 1998-02-24 JP JP53728998A patent/JP2001513096A/ja not_active Ceased
- 1998-02-24 HU HU0001674A patent/HUP0001674A3/hu unknown
- 1998-02-24 DE DE69807245T patent/DE69807245T2/de not_active Expired - Fee Related
- 1998-02-24 AT AT98913582T patent/ATE222233T1/de not_active IP Right Cessation
- 1998-02-24 BR BR9807761A patent/BR9807761A/pt not_active IP Right Cessation
- 1998-02-24 CN CN98802829A patent/CN1248967A/zh active Pending
- 1998-02-24 CA CA002281630A patent/CA2281630C/fr not_active Expired - Fee Related
- 1998-02-24 IL IL13125698A patent/IL131256A/xx not_active IP Right Cessation
- 1998-02-24 AU AU68229/98A patent/AU724276B2/en not_active Ceased
- 1998-02-24 WO PCT/EP1998/001039 patent/WO1998038157A1/fr not_active Ceased
- 1998-02-24 DK DK98913582T patent/DK1019362T3/da active
- 1998-02-24 PL PL98335350A patent/PL188762B1/pl not_active IP Right Cessation
- 1998-02-24 NZ NZ337188A patent/NZ337188A/xx unknown
- 1998-02-24 EE EEP199900361A patent/EE03561B1/xx not_active IP Right Cessation
- 1998-02-24 PT PT98913582T patent/PT1019362E/pt unknown
- 1998-02-24 TR TR1999/02043T patent/TR199902043T2/xx unknown
-
1999
- 1999-08-20 IS IS5160A patent/IS5160A/is unknown
- 1999-08-25 NO NO994110A patent/NO994110L/no not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |