NO995263L - Konjugater av polyetylenglykol og interferon-<alfa> for terapi av infeksjoner - Google Patents

Konjugater av polyetylenglykol og interferon-<alfa> for terapi av infeksjoner

Info

Publication number
NO995263L
NO995263L NO995263A NO995263A NO995263L NO 995263 L NO995263 L NO 995263L NO 995263 A NO995263 A NO 995263A NO 995263 A NO995263 A NO 995263A NO 995263 L NO995263 L NO 995263L
Authority
NO
Norway
Prior art keywords
alpha
interferon
treatment
infections
polyethylene glycol
Prior art date
Application number
NO995263A
Other languages
English (en)
Other versions
NO995263D0 (no
Inventor
Paul Glue
David L Cutler
Melton B Affrime
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO995263D0 publication Critical patent/NO995263D0/no
Publication of NO995263L publication Critical patent/NO995263L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Fremgangsmåte omfattende administrering av et PEG120oo-IFN-alfa-konjugat til et individ rammet av en virusinfeksjon følsom for behandling med interferon-alfa, fortrinnsvis kronisk hepatitt C beskrives.
NO995263A 1997-04-29 1999-10-28 Konjugater av polyetylenglykol og interferon-<alfa> for terapi av infeksjoner NO995263L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/839,101 US5908621A (en) 1995-11-02 1997-04-29 Polyethylene glycol modified interferon therapy
PCT/US1998/007634 WO1998048840A1 (en) 1997-04-29 1998-04-28 Polyethylene glycol-interferon alpha conjugates for therapy of infection

Publications (2)

Publication Number Publication Date
NO995263D0 NO995263D0 (no) 1999-10-28
NO995263L true NO995263L (no) 1999-12-27

Family

ID=25278858

Family Applications (1)

Application Number Title Priority Date Filing Date
NO995263A NO995263L (no) 1997-04-29 1999-10-28 Konjugater av polyetylenglykol og interferon-<alfa> for terapi av infeksjoner

Country Status (26)

Country Link
US (3) US5908621A (no)
EP (1) EP0975369B1 (no)
JP (1) JP2001524110A (no)
KR (1) KR20010020355A (no)
CN (1) CN1261806A (no)
AR (1) AR012614A1 (no)
AT (1) ATE255421T1 (no)
AU (1) AU7249098A (no)
BR (1) BR9809425A (no)
CA (1) CA2288038C (no)
CO (1) CO4940414A1 (no)
DE (1) DE69820247T2 (no)
DK (1) DK0975369T3 (no)
ES (1) ES2207830T3 (no)
HU (1) HUP0003131A2 (no)
ID (1) ID22977A (no)
IL (1) IL132582A0 (no)
MY (1) MY133891A (no)
NO (1) NO995263L (no)
NZ (1) NZ500763A (no)
PE (1) PE72799A1 (no)
PL (1) PL336576A1 (no)
PT (1) PT975369E (no)
SK (1) SK149199A3 (no)
WO (1) WO1998048840A1 (no)
ZA (1) ZA983543B (no)

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