NO995745L - Nye derivater av erytromycin, fremgangsmÕte for fremstilling av disse, samt deres anvendelse som medikamenter - Google Patents

Nye derivater av erytromycin, fremgangsmÕte for fremstilling av disse, samt deres anvendelse som medikamenter

Info

Publication number: NO995745L
Authority: NO; Norway
Prior art keywords: erythromycin; medicaments; preparation; new derivatives; derivatives
Prior art date: 1998-11-24

Application number

NO995745A

Other languages

English (en)

Other versions

NO995745D0 (no

NO314729B1 (no

Inventor

Chimiste Cadre

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-24

Filing date

1999-11-23

Publication date

2000-05-25

1999-11-23 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1999-11-23 Publication of NO995745D0 publication Critical patent/NO995745D0/no

2000-05-25 Publication of NO995745L publication Critical patent/NO995745L/no

2003-05-12 Publication of NO314729B1 publication Critical patent/NO314729B1/no

Links

ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

NO19995745A 1998-11-24 1999-11-23 Nye derivater av erytromycin, fremgangsmåte for fremstilling av disse, medikamenter som inneholder disse, samt nye forbindelser som ermellomprodukter vedfremstillingen av derivatene NO314729B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9814782A FR2786188B1 (fr)	1998-11-24	1998-11-24	Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments

Publications (3)

Publication Number	Publication Date
NO995745D0 NO995745D0 (no)	1999-11-23
NO995745L true NO995745L (no)	2000-05-25
NO314729B1 NO314729B1 (no)	2003-05-12

Family

ID=9533122

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19995745A NO314729B1 (no)	1998-11-24	1999-11-23	Nye derivater av erytromycin, fremgangsmåte for fremstilling av disse, medikamenter som inneholder disse, samt nye forbindelser som ermellomprodukter vedfremstillingen av derivatene

Country Status (24)

Country	Link
US (2)	US6440941B1 (no)
EP (1)	EP1004592B1 (no)
JP (1)	JP2000159790A (no)
KR (1)	KR100587445B1 (no)
CN (1)	CN1165546C (no)
AR (1)	AR021388A1 (no)
AT (1)	ATE245160T1 (no)
AU (1)	AU772171B2 (no)
BR (1)	BR9905735A (no)
CA (1)	CA2290136C (no)
DE (1)	DE69909577T2 (no)
DK (1)	DK1004592T3 (no)
ES (1)	ES2198867T3 (no)
FR (1)	FR2786188B1 (no)
HU (1)	HUP9904392A3 (no)
IL (1)	IL133101A (no)
MX (1)	MXPA99010813A (no)
NO (1)	NO314729B1 (no)
PL (1)	PL336736A1 (no)
PT (1)	PT1004592E (no)
RU (1)	RU2237672C2 (no)
TR (1)	TR199902888A2 (no)
TW (1)	TWI247747B (no)
ZA (1)	ZA997176B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2786188B1 (fr) *	1998-11-24	2002-10-31	Hoechst Marion Roussel Inc	Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
AP2001002222A0 (en)	1999-01-27	2001-09-30	Pfizer Prod Inc	Ketolide antibiotics.
IL145739A0 (en)	1999-05-24	2002-07-25	Pfizer Prod Inc	13-methyl-erythromycin derivatives
TR200401847T4 (tr)	2000-06-30	2004-09-21	Pfizer Products Inc.	Makrolit antibiyotikler.
EP1638549A4 (en)	2003-03-10	2011-06-15	Optimer Pharmaceuticals Inc	NEW ANTIBACTERIAL AGENTS
FR2862647B1 (fr) *	2003-11-25	2008-07-04	Aventis Pharma Sa	Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant
RU2397987C2 (ru) *	2004-07-28	2010-08-27	Рэнбакси Лабораториз Лимитед	Кетолидные производные в качестве антибактериальных агентов
CA2703475A1 (en) *	2007-10-25	2009-04-30	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
WO2009137787A1 (en)	2008-05-09	2009-11-12	Enanta Pharmaceuticals, Inc.	Processes for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives
US8796232B2 (en) *	2008-10-24	2014-08-05	Cempra Pharmaceuticals, Inc.	Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja)	2009-09-10	2016-05-11	センプラファーマシューティカルズ，インコーポレイテッド	マラリア、結核、及びｍａｃ病の治療方法
CN103080122A (zh)	2010-03-22	2013-05-01	森普拉制药公司	大环内脂的结晶形式及其用途
WO2011146829A1 (en)	2010-05-20	2011-11-24	Cempra Pharmaceuticals, Inc.	Processes for preparing macrolides and ketolides and intermediates therefor
JP6042334B2 (ja) *	2010-09-10	2016-12-14	センプラファーマシューティカルズ，インコーポレイテッド	疾患治療のための水素結合形成フルオロケトライド
WO2012052412A1 (de)	2010-10-22	2012-04-26	Bayer Cropscience Ag	Neue heterocylische verbindungen als schädlingsbekämpfungsmittel
CN104470527B (zh)	2012-03-27	2019-05-28	森普拉制药公司	用于施用大环内酯抗生素的肠胃外制剂
RU2015138796A (ru)	2013-03-14	2017-04-19	Семпра Фармасьютикалс, Инк.	Способы и составы для лечения респираторных заболеваний
WO2014145210A1 (en)	2013-03-15	2014-09-18	Cempra Pharmaceuticals, Inc.	Convergent processes for preparing macrolide antibacterial agents
CN106432383A (zh) *	2016-09-14	2017-02-22	重庆两江药物研发中心有限公司	索利霉素及其中间体的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4182895A (en) *	1976-12-20	1980-01-08	Sterling Drug Inc.	1-Amino-lower-alkyl-3,4-diphenyl-1H-pyrazoles
CA1098527A (en) *	1976-12-20	1981-03-31	Denis M. Bailey	1-amino-lower-alkyl-3,4-diphenyl-1h-pyrazoles
JPH04234891A (ja) *	1990-03-05	1992-08-24	Fujisawa Pharmaceut Co Ltd	新規セフェム化合物およびその塩
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2697524B1 (fr) *	1992-11-05	1994-12-23	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2718450B1 (fr) *	1994-04-08	1997-01-10	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) *	1994-05-03	1996-07-12	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) *	1994-12-09	1997-01-17	Roussel Uclaf	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) *	1995-12-22	1998-01-30	Roussel Uclaf	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
CN1259135A (zh) *	1997-06-11	2000-07-05	辉瑞产品公司	9－肟红霉素衍生物
FR2786188B1 (fr) *	1998-11-24	2002-10-31	Hoechst Marion Roussel Inc	Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments

1998
- 1998-11-24 FR FR9814782A patent/FR2786188B1/fr not_active Expired - Fee Related
1999
- 1999-11-16 TW TW088119939A patent/TWI247747B/zh not_active IP Right Cessation
- 1999-11-17 AU AU59522/99A patent/AU772171B2/en not_active Expired
- 1999-11-18 US US09/442,681 patent/US6440941B1/en not_active Expired - Lifetime
- 1999-11-18 ZA ZA9907176A patent/ZA997176B/xx unknown
- 1999-11-18 CA CA2290136A patent/CA2290136C/fr not_active Expired - Lifetime
- 1999-11-22 JP JP11331141A patent/JP2000159790A/ja active Pending
- 1999-11-23 HU HU9904392A patent/HUP9904392A3/hu unknown
- 1999-11-23 IL IL133101A patent/IL133101A/en not_active IP Right Cessation
- 1999-11-23 MX MXPA99010813A patent/MXPA99010813A/es active IP Right Grant
- 1999-11-23 DE DE69909577T patent/DE69909577T2/de not_active Expired - Lifetime
- 1999-11-23 NO NO19995745A patent/NO314729B1/no unknown
- 1999-11-23 ES ES99402907T patent/ES2198867T3/es not_active Expired - Lifetime
- 1999-11-23 RU RU99125547A patent/RU2237672C2/ru not_active IP Right Cessation
- 1999-11-23 AT AT99402907T patent/ATE245160T1/de active
- 1999-11-23 DK DK99402907T patent/DK1004592T3/da active
- 1999-11-23 CN CNB99127394XA patent/CN1165546C/zh not_active Expired - Lifetime
- 1999-11-23 EP EP99402907A patent/EP1004592B1/fr not_active Expired - Lifetime
- 1999-11-23 PT PT99402907T patent/PT1004592E/pt unknown
- 1999-11-23 KR KR1019990052014A patent/KR100587445B1/ko not_active Expired - Lifetime
- 1999-11-24 AR ARP990105985A patent/AR021388A1/es not_active Application Discontinuation
- 1999-11-24 TR TR1999/02888A patent/TR199902888A2/xx unknown
- 1999-11-24 BR BR9905735-2A patent/BR9905735A/pt active Search and Examination
- 1999-11-24 PL PL99336736A patent/PL336736A1/xx not_active Application Discontinuation
2002
- 2002-07-02 US US10/188,394 patent/US6664398B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP2000159790A (ja)	2000-06-13
ATE245160T1 (de)	2003-08-15
CN1263101A (zh)	2000-08-16
PL336736A1 (en)	2000-06-05
AU5952299A (en)	2000-05-25
HUP9904392A2 (hu)	2000-05-28
TWI247747B (en)	2006-01-21
DE69909577D1 (de)	2003-08-21
CA2290136A1 (fr)	2000-05-24
PT1004592E (pt)	2003-12-31
ZA997176B (en)	2000-11-20
DK1004592T3 (da)	2003-10-27
TR199902888A3 (tr)	2000-06-21
AR021388A1 (es)	2002-07-17
EP1004592B1 (fr)	2003-07-16
TR199902888A2 (xx)	2000-06-21
AU772171B2 (en)	2004-04-08
NO995745D0 (no)	1999-11-23
MXPA99010813A (es)	2005-09-08
IL133101A0 (en)	2001-03-19
FR2786188B1 (fr)	2002-10-31
KR20000057017A (ko)	2000-09-15
CN1165546C (zh)	2004-09-08
HUP9904392A3 (en)	2001-08-28
US20030050254A1 (en)	2003-03-13
EP1004592A1 (fr)	2000-05-31
IL133101A (en)	2007-02-11
US6664398B2 (en)	2003-12-16
US6440941B1 (en)	2002-08-27
KR100587445B1 (ko)	2006-06-08
HU9904392D0 (en)	2000-01-28
CA2290136C (fr)	2010-07-20
BR9905735A (pt)	2000-08-08
DE69909577T2 (de)	2004-06-03
ES2198867T3 (es)	2004-02-01
FR2786188A1 (fr)	2000-05-26
NO314729B1 (no)	2003-05-12
RU2237672C2 (ru)	2004-10-10

Publication	Publication Date	Title
NO995745D0 (no)	1999-11-23	Nye derivater av erytromycin, fremgangsmåte for fremstilling av disse, samt deres anvendelse som medikamenter
NO954942D0 (no)	1995-12-06	Nye erytromycinderivater, fremgangsmåte for deres fremstilling og anvendelse av derivatene som legemidler
DK0680967T3 (da)	1999-06-23	Nye forbindelser afledt af erythromycin, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler
NO20032735L (no)	2003-08-06	Difenylazetidinonderivater, fremgangsmåte for deres fremstilling, legemidler som inneholder disse forbindelsene samt deres anvendelse
NO20006251D0 (no)	2000-12-08	Benzotiepin-1,1-dioksidderivater, fremgangsmåte for deres fremstilling, legemidler som inneholder disse forbindelsene og deres anvendelse
NO20003496L (no)	2000-09-08	Nye aromatiske amider, fremgangsmÕte for fremstilling av disse, samt deres anvendelse som medisiner
DK1016669T3 (da)	2003-05-26	Nye erythromycinderivater, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler
NO983955D0 (no)	1998-08-27	Nye erytromycinderivater, metode for fremstilling av disse og anvendelse derav som legemidler
NO20032733D0 (no)	2003-06-16	Difenyl azetidinonderivater, fremgangsmåte for deres fremstilling, legemidler som inneholder disse forbindelsene samt deres anvendelse
NO20012156L (no)	2001-07-02	Pyrazolopyridinderivater som selektive COX-2 inhibitorer
NO20000294L (no)	2000-03-17	Derivater av acylpiperazinylpyrimidiner, deres fremstilling og anvendelse som legemidler
NO20010568D0 (no)	2001-02-02	Substituerte imidazo[1,2a]aziner som selektive inhibitorer for cox-2
NO20003661L (no)	2000-09-19	Nye pentasakkarider, fremgangsmÕter for deres fremstilling og farmasøytiske preparater inneholdende de samme
DK0782575T3 (da)	2003-05-12	Substituerede pyrazol-pyrazol-derivater, fremgangsmåde til deres fremsstilling samt deres anvendelse som midler med herbicid virkning
NO983860D0 (no)	1998-08-21	Nye triazolopuriner, fremgangsmÕte for fremstilling av dem og deres anvendelse som legemidler
NO990302L (no)	1999-03-23	Nye derivater av erytromycin, fremgangsmÕte for fremstilling av slike, samt deres anvendelse som medikamenter
NO985790D0 (no)	1998-12-10	Nye aromatiske derivater substituert med ribose, fremgangsmÕte for fremstilling derav samt deres anvendelse som medikamenter
NO992859D0 (no)	1999-06-11	Nye derivater av erytromycin, fremgangsmÕte for fremstilling av disse og deres anvendelse som medikamenter
NO20004638L (no)	2000-11-16	Hypnotisk <beta>- karbolinderivater, fremgangsmÕte til deres fremstilling og deres anvendelse som legemiddelprodukt
NO20024590D0 (no)	2002-09-25	Farmasöytiske preparater inneholdende oligosakkarider, de nye oligosakkarider samt deres fremstilling
NO993124D0 (no)	1999-06-23	Nye erytromycinderivater, fremgangsmÕte for fremstilling av disse samt deres anvendelse som medisiner
NO990675D0 (no)	1999-02-12	11-acetyl-12,13-dioksabisyklo[8.2.1.]-tridekenonderivater, fremgangsmÕter for deres fremstilling, samt legemidler inneholdende slike forbindelser
NO984547D0 (no)	1998-09-29	Nye oksazolidinderivater, fremgangsmÕte for deres fremstilling, samt legemidler inneholdende disse forbindelser
NO963129D0 (no)	1996-07-26	Nye leukotrien-B4-derivater, fremgangsmåte for fremstilling derav og anvendelse derav som legemidler
NO20006573L (no)	2001-02-22	Nye 17-halogenerte 19-nor-steroider, metode og mellomprodukter for fremstilling av disse, anvendelse som medisiner og farmasöytiske preparater inneholdende disse