NO996285L - Nye spiroimidazolinforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem - Google Patents

Nye spiroimidazolinforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem

Info

Publication number: NO996285L
Authority: NO; Norway
Prior art keywords: new; preparation; pharmaceutical compositions; spiroimidazoline; compounds
Prior art date: 1998-12-18

Application number

NO996285A

Other languages

English (en)

Other versions

NO996285D0 (no

NO314402B1 (no

Inventor

Alex Cordi

Mark Millan

Adrian Newman-Tancredi

Mauricette Brocco

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-18

Filing date

1999-12-17

Publication date

2000-06-19

1999-12-17 Application filed by Adir filed Critical Adir

1999-12-17 Publication of NO996285D0 publication Critical patent/NO996285D0/no

2000-06-19 Publication of NO996285L publication Critical patent/NO996285L/no

2003-03-17 Publication of NO314402B1 publication Critical patent/NO314402B1/no

Links

150000001875 compounds Chemical class 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
-1 cyano, nitro, amino Chemical group 0.000 abstract 2
125000003003 spiro group Chemical group 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000004963 sulfonylalkyl group Chemical group 0.000 abstract 1
125000004001 thioalkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Child & Adolescent Psychology (AREA)
Gynecology & Obstetrics (AREA)
Cardiology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Addiction (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Obesity (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO19996285A 1998-12-18 1999-12-17 Nye spiroimidazolinforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem NO314402B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9816000A FR2787450B1 (fr)	1998-12-18	1998-12-18	Nouveaux derives spiroimidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number	Publication Date
NO996285D0 NO996285D0 (no)	1999-12-17
NO996285L true NO996285L (no)	2000-06-19
NO314402B1 NO314402B1 (no)	2003-03-17

Family

ID=9534134

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19996285A NO314402B1 (no)	1998-12-18	1999-12-17	Nye spiroimidazolinforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem

Country Status (21)

Country	Link
US (1)	US6172097B1 (no)
EP (1)	EP1010694B1 (no)
JP (1)	JP3457241B2 (no)
KR (1)	KR100472522B1 (no)
CN (1)	CN1149201C (no)
AT (1)	ATE246680T1 (no)
AU (1)	AU760373B2 (no)
BR (1)	BR9905904A (no)
CA (1)	CA2292920C (no)
DE (1)	DE69910156T2 (no)
DK (1)	DK1010694T3 (no)
EA (1)	EA002979B1 (no)
ES (1)	ES2205741T3 (no)
FR (1)	FR2787450B1 (no)
HU (1)	HU225820B1 (no)
NO (1)	NO314402B1 (no)
NZ (1)	NZ501890A (no)
PL (1)	PL202368B1 (no)
PT (1)	PT1010694E (no)
SI (1)	SI1010694T1 (no)
ZA (1)	ZA997735B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6638981B2 (en)	2001-08-17	2003-10-28	Epicept Corporation	Topical compositions and methods for treating pain
CA2716080C (en)	2008-02-20	2016-12-13	Targia Pharmaceuticals	Cns pharmaceutical compositions and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5017584A (en)	1984-12-20	1991-05-21	Sterling Drug Inc.	Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas
US6294185B1 (en) *	1993-03-12	2001-09-25	Auburn University	Monomeric and polymeric cyclic amine and N-halamine compounds
FR2707982B1 (fr) *	1993-07-20	1995-09-01	Adir	Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2709306B1 (fr) *	1993-07-20	1995-10-20	Adir	Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2707981B1 (fr) *	1993-07-20	1995-09-01	Adir	Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

1998
- 1998-12-18 FR FR9816000A patent/FR2787450B1/fr not_active Expired - Fee Related
1999
- 1999-12-16 JP JP35716799A patent/JP3457241B2/ja not_active Expired - Fee Related
- 1999-12-17 DE DE69910156T patent/DE69910156T2/de not_active Expired - Lifetime
- 1999-12-17 AT AT99403189T patent/ATE246680T1/de not_active IP Right Cessation
- 1999-12-17 ZA ZA9907735A patent/ZA997735B/xx unknown
- 1999-12-17 CN CNB991278305A patent/CN1149201C/zh not_active Expired - Fee Related
- 1999-12-17 US US09/465,619 patent/US6172097B1/en not_active Expired - Fee Related
- 1999-12-17 NO NO19996285A patent/NO314402B1/no not_active IP Right Cessation
- 1999-12-17 PT PT99403189T patent/PT1010694E/pt unknown
- 1999-12-17 AU AU65291/99A patent/AU760373B2/en not_active Ceased
- 1999-12-17 EA EA199901049A patent/EA002979B1/ru not_active IP Right Cessation
- 1999-12-17 SI SI9930368T patent/SI1010694T1/xx unknown
- 1999-12-17 BR BR9905904-5A patent/BR9905904A/pt not_active Application Discontinuation
- 1999-12-17 EP EP99403189A patent/EP1010694B1/fr not_active Expired - Lifetime
- 1999-12-17 NZ NZ501890A patent/NZ501890A/xx not_active IP Right Cessation
- 1999-12-17 CA CA002292920A patent/CA2292920C/fr not_active Expired - Fee Related
- 1999-12-17 HU HU9904629A patent/HU225820B1/hu not_active IP Right Cessation
- 1999-12-17 PL PL337265A patent/PL202368B1/pl not_active IP Right Cessation
- 1999-12-17 ES ES99403189T patent/ES2205741T3/es not_active Expired - Lifetime
- 1999-12-17 DK DK99403189T patent/DK1010694T3/da active
- 1999-12-18 KR KR10-1999-0058931A patent/KR100472522B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1010694B1 (fr)	2003-08-06
DK1010694T3 (da)	2003-11-24
HU9904629D0 (en)	2000-02-28
HUP9904629A3 (en)	2000-12-28
EA199901049A3 (ru)	2000-08-28
JP3457241B2 (ja)	2003-10-14
FR2787450B1 (fr)	2001-01-26
NO996285D0 (no)	1999-12-17
HUP9904629A2 (hu)	2000-08-28
CA2292920C (fr)	2004-01-27
EA002979B1 (ru)	2002-12-26
ATE246680T1 (de)	2003-08-15
KR20000067830A (ko)	2000-11-25
ES2205741T3 (es)	2004-05-01
CN1149201C (zh)	2004-05-12
AU6529199A (en)	2000-06-22
HU225820B1 (en)	2007-10-29
US6172097B1 (en)	2001-01-09
AU760373B2 (en)	2003-05-15
DE69910156T2 (de)	2004-06-09
HK1029117A1 (en)	2001-03-23
BR9905904A (pt)	2000-08-29
EP1010694A2 (fr)	2000-06-21
PT1010694E (pt)	2003-10-31
NZ501890A (en)	2001-03-30
NO314402B1 (no)	2003-03-17
DE69910156D1 (de)	2003-09-11
PL202368B1 (pl)	2009-06-30
SI1010694T1 (en)	2003-12-31
KR100472522B1 (ko)	2005-03-07
CA2292920A1 (fr)	2000-06-18
EA199901049A2 (ru)	2000-08-28
PL337265A1 (en)	2000-06-19
FR2787450A1 (fr)	2000-06-23
CN1264704A (zh)	2000-08-30
EP1010694A3 (fr)	2000-07-26
JP2000178257A (ja)	2000-06-27
ZA997735B (en)	2000-06-19

Legal Events

Date	Code	Title	Description
2011-07-25	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
HK1046685A1 (zh)	2003-01-24	治療用喹唑啉衍生物
DK1029853T3 (da)	2004-05-24	Heteroaromatiske bicykliske derivativer, der er egnede som anticancermidler
DK0928788T3 (da)	2003-03-24	Imidazolidin-4-on-derivater, der er nyttige som anticancer-midler
EP0902007A4 (en)	1999-10-13	CHALCONE DERIVATIVES AND MEDICINES CONTAINING THEM
BR0108893B1 (pt)	2013-06-04	composiÇço farmacÊutica contendo derivados de azetidina, composto derivado de azetidina, e, processo para a preparaÇço de compostos.
AU4777990A (en)	1990-07-12	2-aminopyrimidinone derivatives
AU6976394A (en)	1995-01-17	Aminoacid derivatives as no synthase inhibitors
AU5795694A (en)	1994-09-29	New bicyclic nitrogen compounds, process for preparing them and pharmaceutical compositions containing them
NO996284D0 (no)	1999-12-17	Nye imidazolinforbindelser, fremgangsmåte ved deres fremstilling og farmasoeytiske sammensetninger inneholdende dem
AU5879798A (en)	1998-09-08	Agents inhibiting progress of pterygium and postoperative recurrence of the same
NO996285D0 (no)	1999-12-17	Nye spiroimidazolinforbindelser, fremgangsmåte ved deres fremstilling og farmasoeytiske sammensetninger inneholdende dem
EE04746B1 (et)	2006-12-15	5-asendatud-1,2,4-tiadiasolüülderivaadid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon, vaheühend ja selle valmistamismeetod
AU4842297A (en)	1998-06-18	New N-benzylpiperazine compounds, process for their preparation and the pharmaceutical compositions which contain them
DK0710658T3 (da)	2001-11-26	5-(aryloxymethyl)oxazoliner, fremgangsmåde til deres fremstilling og farmaceutisk sammensætning, der indeholder dem
NO972943L (no)	1997-12-29	4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende dem og deres anvendelse
AU1890299A (en)	1999-08-02	Potassium channel activators
AU4084889A (en)	1990-03-08	Antihypertensive 3-piperidinyl-indazole derivatives
AU2003256091A1 (en)	2004-06-15	1,2,4-triazole derivative, method for preparing the same, and pharmaceutical composition containing the same
BR0201312A (pt)	2003-06-10	Compostos de pirimidin-4-ona, processo para sua preparação e composições farmacêuticas contendo os referidos