NZ238571A - N-benzyl-n'-phenyl and -phenalkyl thioureas and pharmaceutical compositions thereof - Google Patents

N-benzyl-n'-phenyl and -phenalkyl thioureas and pharmaceutical compositions thereof

Info

Publication number: NZ238571A
Authority: NZ; New Zealand
Prior art keywords: 5alkyl; hydrogen; pharmaceutical compositions; substituted; phenalkyl
Prior art date: 1990-06-18

Application number

NZ238571A

Other languages

English (en)

Inventor

Christopher Simon John Walpole

Roger Wrigglesworth

Original Assignee

Sandoz Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-18

Filing date

1991-06-17

Publication date

1993-08-26

1990-06-18 Priority claimed from GB909013575A external-priority patent/GB9013575D0/en

1990-06-22 Priority claimed from GB909013953A external-priority patent/GB9013953D0/en

1991-06-17 Application filed by Sandoz Ltd filed Critical Sandoz Ltd

1993-08-26 Publication of NZ238571A publication Critical patent/NZ238571A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
150000003585 thioureas Chemical class 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
150000001721 carbon Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
- C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NZ238571A 1990-06-18 1991-06-17 N-benzyl-n'-phenyl and -phenalkyl thioureas and pharmaceutical compositions thereof NZ238571A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB909013575A GB9013575D0 (en)	1990-06-18	1990-06-18	Improvements in or relating to organic compounds
GB909013953A GB9013953D0 (en)	1990-06-22	1990-06-22	Improvements in or relating to organic compounds

Publications (1)

Publication Number	Publication Date
NZ238571A true NZ238571A (en)	1993-08-26

Family

ID=26297217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NZ238571A NZ238571A (en)	1990-06-18	1991-06-17	N-benzyl-n'-phenyl and -phenalkyl thioureas and pharmaceutical compositions thereof

Country Status (17)

Country	Link
EP (1)	EP0462933B1 (cs)
JP (1)	JPH0753708B2 (cs)
KR (1)	KR920000715A (cs)
AT (1)	ATE106866T1 (cs)
AU (1)	AU645090B2 (cs)
CA (1)	CA2044797A1 (cs)
CS (1)	CS185091A3 (cs)
DE (1)	DE69102352T2 (cs)
DK (1)	DK0462933T3 (cs)
ES (1)	ES2054474T3 (cs)
FI (1)	FI912903A7 (cs)
HU (1)	HU210683B (cs)
IE (1)	IE912055A1 (cs)
IL (1)	IL98522A0 (cs)
NZ (1)	NZ238571A (cs)
PL (1)	PL290703A1 (cs)
PT (1)	PT98004A (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9519270D0 (en) *	1995-09-21	1995-11-22	Sandoz Pharma Uk	Organic compounds
PL348178A1 (en) *	1998-12-09	2002-05-06	American Home Prod	Thiourea inhibitors of herpes viruses
US6255349B1 (en)	1998-12-09	2001-07-03	American Home Products Corporation	Alph-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
DK1137645T3 (da) *	1998-12-09	2004-08-09	Wyeth Corp	Alfa-methylbenzylholdige thiourinstofinhibitorer af herpesvira indeholdende en phenylendiamingruppe
US6207715B1 (en)	1998-12-09	2001-03-27	American Home Products Corporation	Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a substituted phenylene-diamine group
US6545182B2 (en) *	2000-04-13	2003-04-08	Allergan Sales, Inc.	Methods and compositions for modulating alpha adrenergic receptor activity
US6313172B1 (en) *	2000-04-13	2001-11-06	Allergan Sales, Inc.	Methods and compositions for modulating alpha adrenergic receptor activity
ATE328868T1 (de)	2000-08-21	2006-06-15	Pacific Corp	Neue (thio)harnstoffverbindungen und arzneimittelkompositionen, die diese enthalten
AU2001280229B2 (en)	2000-08-21	2006-12-07	Pacific Corporation	Novel thiourea derivatives and the pharmaceutical compositions containing the same
TWI239942B (en)	2001-06-11	2005-09-21	Dainippon Pharmaceutical Co	N-arylphenylacetamide derivative and pharmaceutical composition containing the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4460602A (en) *	1981-06-30	1984-07-17	The Procter & Gamble Company	Urea derivatives
ES2061624T3 (es) *	1987-03-09	1994-12-16	Procter & Gamble	Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen.
GB8715357D0 (en) *	1987-06-30	1987-08-05	Sandoz Inst For Medical Resear	Organic compounds
HU206082B (en) *	1988-12-23	1992-08-28	Sandoz Ag	Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds

1991
- 1991-06-04 HU HU911862A patent/HU210683B/hu not_active IP Right Cessation
- 1991-06-14 FI FI912903A patent/FI912903A7/fi not_active Application Discontinuation
- 1991-06-17 IE IE205591A patent/IE912055A1/en unknown
- 1991-06-17 KR KR1019910010055A patent/KR920000715A/ko not_active Withdrawn
- 1991-06-17 CA CA002044797A patent/CA2044797A1/en not_active Abandoned
- 1991-06-17 ES ES91810459T patent/ES2054474T3/es not_active Expired - Lifetime
- 1991-06-17 JP JP3144789A patent/JPH0753708B2/ja not_active Expired - Lifetime
- 1991-06-17 AT AT91810459T patent/ATE106866T1/de not_active IP Right Cessation
- 1991-06-17 PL PL29070391A patent/PL290703A1/xx unknown
- 1991-06-17 DE DE69102352T patent/DE69102352T2/de not_active Expired - Fee Related
- 1991-06-17 CS CS911850A patent/CS185091A3/cs unknown
- 1991-06-17 NZ NZ238571A patent/NZ238571A/xx unknown
- 1991-06-17 IL IL98522A patent/IL98522A0/xx unknown
- 1991-06-17 PT PT98004A patent/PT98004A/pt not_active Application Discontinuation
- 1991-06-17 AU AU78438/91A patent/AU645090B2/en not_active Ceased
- 1991-06-17 EP EP91810459A patent/EP0462933B1/en not_active Expired - Lifetime
- 1991-06-17 DK DK91810459.7T patent/DK0462933T3/da active

Also Published As

Publication number	Publication date
ATE106866T1 (de)	1994-06-15
DE69102352D1 (de)	1994-07-14
JPH04230257A (ja)	1992-08-19
EP0462933B1 (en)	1994-06-08
IL98522A0 (en)	1992-07-15
PT98004A (pt)	1992-03-31
ES2054474T3 (es)	1994-08-01
EP0462933A1 (en)	1991-12-27
DE69102352T2 (de)	1994-11-17
AU7843891A (en)	1991-12-19
CS185091A3 (en)	1992-01-15
PL290703A1 (en)	1992-09-21
DK0462933T3 (da)	1994-08-15
JPH0753708B2 (ja)	1995-06-07
CA2044797A1 (en)	1991-12-19
HU210683B (en)	1995-06-28
KR920000715A (ko)	1992-01-29
FI912903A0 (fi)	1991-06-14
HUT59090A (en)	1992-04-28
IE912055A1 (en)	1991-12-18
FI912903A7 (fi)	1991-12-19
HU911862D0 (en)	1991-12-30
AU645090B2 (en)	1994-01-06

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