NZ331637A - Trans 9-substituted 3,4,4a,5,6,10b-hexahydro-4(alkyl, alkenyl or alkynyl)-2h-naphth[1,2-b]-1,4-oxazine derivatives and medicaments - Google Patents

Trans 9-substituted 3,4,4a,5,6,10b-hexahydro-4(alkyl, alkenyl or alkynyl)-2h-naphth[1,2-b]-1,4-oxazine derivatives and medicaments

Info

Publication number: NZ331637A
Authority: NZ; New Zealand
Prior art keywords: alkyl; hexahydro; alkynyl; trans; alkenyl
Prior art date: 1997-09-01

Application number

NZ331637A

Other languages

English (en)

Inventor

Jean-Louis Peglion

Jean-Christophe Harmange

Mark Millan

Francoise Lejeune

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-01

Filing date

1998-08-31

Publication date

1999-07-29

1998-08-31 Application filed by Adir filed Critical Adir

1999-07-29 Publication of NZ331637A publication Critical patent/NZ331637A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NZ331637A 1997-09-01 1998-08-31 Trans 9-substituted 3,4,4a,5,6,10b-hexahydro-4(alkyl, alkenyl or alkynyl)-2h-naphth[1,2-b]-1,4-oxazine derivatives and medicaments NZ331637A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9710852A FR2767825A1 (fr)	1997-09-01	1997-09-01	Nouvelles trans-3,4,4a,5,6,10b-hexahydro-2h-napht°1,2-b!-1, 4-oxazines disubstituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
NZ331637A true NZ331637A (en)	1999-07-29

Family

ID=9510643

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NZ331637A NZ331637A (en)	1997-09-01	1998-08-31	Trans 9-substituted 3,4,4a,5,6,10b-hexahydro-4(alkyl, alkenyl or alkynyl)-2h-naphth[1,2-b]-1,4-oxazine derivatives and medicaments

Country Status (18)

Country	Link
US (1)	US6025356A (2)
EP (1)	EP0899267B1 (2)
JP (1)	JP4417451B2 (2)
CN (1)	CN1088064C (2)
AT (1)	ATE229513T1 (2)
AU (1)	AU740928C (2)
BR (1)	BR9803933A (2)
CA (1)	CA2246482C (2)
DE (1)	DE69810034T2 (2)
DK (1)	DK0899267T3 (2)
ES (1)	ES2189108T3 (2)
FR (1)	FR2767825A1 (2)
HU (1)	HU226059B1 (2)
NO (1)	NO311218B1 (2)
NZ (1)	NZ331637A (2)
PL (1)	PL194533B1 (2)
PT (1)	PT899267E (2)
ZA (1)	ZA987963B (2)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0130219D0 (en) *	2001-12-18	2002-02-06	Pfizer Ltd	Compounds for the treatment of sexual dysfunction
AU2003268292A1 (en) *	2002-08-30	2004-03-19	Biostratum, Inc.	Inhibitors of post-amadori advanced glycation end products
BRPI0409492A (pt) *	2003-04-18	2006-05-02	Pharmacia & Up John Company Ll	terapias de combinação
FR2906249B1 (fr) *	2006-09-26	2008-12-19	Servier Lab	Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2098511A1 (en)	2008-03-07	2009-09-09	Solvias AG	Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
JP2011525893A (ja) *	2008-06-27	2011-09-29	ハー・ルンドベック・アクチエゼルスカベット	新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1204745A (en) *	1981-11-20	1986-05-20	Merck Co.	Hexahydronaphth (1,2-b) -1,4 -oxazines
US4420480A (en) *	1981-11-20	1983-12-13	Merck & Co., Inc.	Hexahydronaphth[1,2-b]-1,4-oxazines
US4540691A (en) *	1984-04-13	1985-09-10	Nelson Research & Development Co.	Dopamine agonists and use thereof
US5486611A (en) *	1989-07-13	1996-01-23	The Upjohn Company	Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives
CA2083146A1 (en) *	1990-06-15	1991-12-16	Gevork Minaskanian	Substituted naphthoxazines useful as dopaminergics

1997
- 1997-09-01 FR FR9710852A patent/FR2767825A1/fr active Pending
1998
- 1998-08-31 US US09/144,025 patent/US6025356A/en not_active Expired - Lifetime
- 1998-08-31 HU HU9801951A patent/HU226059B1/hu not_active IP Right Cessation
- 1998-08-31 PL PL328285A patent/PL194533B1/pl not_active IP Right Cessation
- 1998-08-31 CA CA002246482A patent/CA2246482C/fr not_active Expired - Fee Related
- 1998-08-31 CN CN98119987A patent/CN1088064C/zh not_active Expired - Fee Related
- 1998-08-31 NO NO19984007A patent/NO311218B1/no not_active IP Right Cessation
- 1998-08-31 BR BR9803933-4A patent/BR9803933A/pt not_active Application Discontinuation
- 1998-08-31 NZ NZ331637A patent/NZ331637A/xx not_active IP Right Cessation
- 1998-09-01 DE DE69810034T patent/DE69810034T2/de not_active Expired - Lifetime
- 1998-09-01 ES ES98402155T patent/ES2189108T3/es not_active Expired - Lifetime
- 1998-09-01 PT PT98402155T patent/PT899267E/pt unknown
- 1998-09-01 ZA ZA987963A patent/ZA987963B/xx unknown
- 1998-09-01 JP JP24691098A patent/JP4417451B2/ja not_active Expired - Fee Related
- 1998-09-01 AU AU83024/98A patent/AU740928C/en not_active Ceased
- 1998-09-01 AT AT98402155T patent/ATE229513T1/de active
- 1998-09-01 EP EP98402155A patent/EP0899267B1/fr not_active Expired - Lifetime
- 1998-09-01 DK DK98402155T patent/DK0899267T3/da active

Also Published As

Publication number	Publication date
ATE229513T1 (de)	2002-12-15
PT899267E (pt)	2003-04-30
JP4417451B2 (ja)	2010-02-17
EP0899267B1 (fr)	2002-12-11
NO984007D0 (no)	1998-08-31
CN1088064C (zh)	2002-07-24
EP0899267A1 (fr)	1999-03-03
ES2189108T3 (es)	2003-07-01
US6025356A (en)	2000-02-15
AU740928B2 (en)	2001-11-15
DE69810034D1 (de)	2003-01-23
HK1020340A1 (en)	2000-04-14
NO984007L (no)	1999-03-02
AU8302498A (en)	1999-03-11
CA2246482C (fr)	2002-11-26
HU9801951D0 (en)	1998-11-30
CN1222516A (zh)	1999-07-14
FR2767825A1 (fr)	1999-02-26
AU740928C (en)	2002-05-16
CA2246482A1 (fr)	1999-03-01
HU226059B1 (en)	2008-04-28
BR9803933A (pt)	2001-04-24
PL328285A1 (en)	1999-03-15
DK0899267T3 (da)	2003-03-10
ZA987963B (en)	1999-03-04
JPH11130759A (ja)	1999-05-18
HUP9801951A2 (hu)	2000-02-28
PL194533B1 (pl)	2007-06-29
HUP9801951A3 (en)	2000-04-28
NO311218B1 (no)	2001-10-29
DE69810034T2 (de)	2003-08-14

Legal Events

Date	Code	Title	Description
2002-02-01	ASS	Change of ownership	Owner name: LES LABORATOIRES SERVIER, FR Free format text: OLD OWNER(S): ADIR ET COMPAGNIE
2002-07-26	RENW	Renewal (renewal fees accepted)
2005-06-24	RENW	Renewal (renewal fees accepted)
2008-06-27	RENW	Renewal (renewal fees accepted)
2011-07-29	RENW	Renewal (renewal fees accepted)
2018-08-31	EXPY	Patent expired

Publication	Publication Date	Title
AU2464997A (en)	1997-12-11	New 3-(piperid-4-YL)-1,2-benzisoxazole and 3-piperazin-4-YL)-1,2-benzisoxazole compounds, processes for their preparation and pharmaceutical compositions containing them
HUP0000610A2 (hu)	2000-09-28	Fájdalomcsillapító hatású piperidinszármazékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények
HU9801951D0 (en)	1998-11-30	New disubstituted trans 3,4,4,4a,5,6,10b-hexahydro-2h-napht-[1,2-b]-1,4-oxazine derivatives, process for producing them and pharmaceutical compositions containing them
GR3031051T3 (en)	1999-12-31	Derivatives of indole, indazole and benzisoxazole for the treatment of schizophrenia
AU654125B2 (en)	1994-10-27	Novel diphenylthyazole derivative
MX9200102A (es)	1992-07-01	Derivados de cefalosporinas y composicion farmaceutica que las contiene
EE9500076A (et)	1996-06-17	1,2-sillaga 1,4-dihüdropüridiinide kasutamine ravimitena
AU7170496A (en)	1997-05-15	New tetracyclic 1,4-oxazine compounds, a process for their preparation and pharmaceutical compositions containing them
NZ224956A (en)	1990-07-26	Benzo-thieno-thiazine derivatives, pharmaceuticals and intermediates
EP0412820A3 (en)	1991-11-27	2-oxo-1-oxa-8-azaspiro(4,5) decane derivatives, processes for their preparation and pharmaceutical compositions thereof
ATE220905T1 (de)	2002-08-15	Benzo(b)thiophene derivaten zur verringerung der blutplätchenzahl
AU2052395A (en)	1995-12-14	New tetracyclic piperidine and 1,4-oxazine compounds, a process for their preparation and pharmaceutical compositions containing them
GR3036191T3 (en)	2001-10-31	Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them.
GB2206490B (en)	1991-09-18	Antipsychotic compositions containing dioxopiperidine derivatives
ES8506585A1 (es)	1985-08-01	Un procedimiento para la obtencion de sales de amonio cuaternarias