OA02583A - Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques. - Google Patents

Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques.

Info

Publication number
OA02583A
OA02583A OA52892A OA52892A OA02583A OA 02583 A OA02583 A OA 02583A OA 52892 A OA52892 A OA 52892A OA 52892 A OA52892 A OA 52892A OA 02583 A OA02583 A OA 02583A
Authority
OA
OAPI
Prior art keywords
bis
preparation
basic substituents
carrying basic
benzimidazoles
Prior art date
Application number
OA52892A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of OA02583A publication Critical patent/OA02583A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
OA52892A 1966-04-01 1967-04-01 Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques. OA02583A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0048833 1966-04-01

Publications (1)

Publication Number Publication Date
OA02583A true OA02583A (fr) 1970-05-05

Family

ID=7102516

Family Applications (1)

Application Number Title Priority Date Filing Date
OA52892A OA02583A (fr) 1966-04-01 1967-04-01 Procédé de préparation de bis-benzimidazoles porteurs de substituants basiques.

Country Status (9)

Country Link
US (1) US3538097A (fr)
BE (1) BE696499A (fr)
CH (2) CH525902A (fr)
DE (1) DE1670684A1 (fr)
FR (2) FR1519964A (fr)
GB (1) GB1186723A (fr)
MY (1) MY7100120A (fr)
NL (1) NL6704539A (fr)
OA (1) OA02583A (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
DE3611343A1 (de) * 1986-04-04 1987-10-08 Boehringer Mannheim Gmbh Heterocyclisch substituierte benzimidazole, verfahren zu ihrer herstellung, arzneimittel sowie zwischenprodukte
AU695936B2 (en) * 1994-08-26 1998-08-27 Auckland Division Cancer Society Of New Zealand Inc Novel dna-targeted alkylating agents
US5968933A (en) * 1994-08-26 1999-10-19 Auckland Division Cancer Society Of New Zealand Inc. DNA-targeted alkylating agents
US5767142A (en) * 1996-03-20 1998-06-16 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
US5807874A (en) * 1995-05-17 1998-09-15 Rutgers, The State University Of New Jersey Trisbenzimidazoles useful as topoisomerase I inhibitors
AUPN449295A0 (en) 1995-07-28 1995-08-24 Inner And Eastern Health Care Network, The Radioprotectors
US5981541A (en) * 1996-09-23 1999-11-09 Rutgers, The State University Of New Jersey Substituted heterocycles as anti-tumor agents
US6140328A (en) * 1997-12-12 2000-10-31 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
AU753268B2 (en) * 1997-12-31 2002-10-10 Jun Sung Kim Heterocyclic topoisomerase poisons
IL137351A0 (en) 1998-02-12 2001-07-24 Univ Rutgers Heterocyclic topoisomerase poisons
US6740650B2 (en) 1999-10-29 2004-05-25 Rutgers, The State University Of New Jersey Heterocyclic cytotoxic agents
ATE390923T1 (de) * 2001-11-14 2008-04-15 Univ Rutgers Topoisomerase-giftmittel
ES2311639T3 (es) * 2001-11-14 2009-02-16 Rutgers, The State University Agentes citotoxicos.
JP4789414B2 (ja) * 2001-11-14 2011-10-12 ラトガーズ，ザ ステイト ユニバーシティ 可溶化トポイソメラーゼ毒性剤
WO2003041660A2 (fr) * 2001-11-14 2003-05-22 Rutgers, The State University Poisons de topoisomerase solubilises
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US6992089B2 (en) * 2002-08-09 2006-01-31 Rutgers, The University Of New Jersey Nitro and amino substituted topoisomerase agents
WO2004014918A1 (fr) 2002-08-09 2004-02-19 Rutgers, The State University Agents de la topoisomerase substitues par nitro et amino
WO2004014862A1 (fr) * 2002-08-09 2004-02-19 Rutgers, The State University Heterocycles a substitution nitro et amino utiles en tant qu'agents de ciblage de la topoisomerase i
AU2003290818A1 (en) * 2002-11-12 2004-06-03 Edmond J. Lavoie Topoisomerase-targeting agents
BRPI0515482A (pt) * 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seus usos como agentes terapêuticos
MX2007003332A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de estearoil-coa-desaturasa.
CA2618646A1 (fr) * 2005-06-03 2007-11-15 Xenon Pharmaceuticals Inc. Derives aminothiazole utilises en tant qu'inhibiteurs de la stearoyle-coa desaturase humaine
PT2114896E (pt) * 2006-12-21 2015-11-04 Peter Maccallum Cancer Inst Compostos radio-protetores e métodos relacionados
GB0821913D0 (en) 2008-12-02 2009-01-07 Price & Co Antibacterial compounds
DK2403856T3 (da) 2009-03-06 2013-04-08 Univ Rutgers Methylendioxybenzo[i]phenanthridinderivater anvendt til behandling af cancer
WO2010127363A1 (fr) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Inhibiteurs de topoisomérase
JP5712524B2 (ja) * 2009-10-28 2015-05-07 Jsr株式会社 液晶配向剤および液晶表示素子
ES2803556T3 (es) * 2010-06-01 2021-01-27 Summit Oxford Ltd Compuestos para el tratamiento de enfermedades asociadas a clostridium difficile
CA2836487A1 (fr) * 2011-06-09 2012-12-13 Rhizen Pharmaceuticals Sa Nouveaux composes utilises comme modulateurs de gpr-119
GB201506658D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
GB201506660D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
WO2017125944A1 (fr) * 2016-01-23 2017-07-27 Jawaharlal Nehru University (Jnu) Activité antibactérienne à large spectre de nouveaux bisbenzimidazoles ciblant la topoisomérase ia et composition synergique associant bisbenzimidazole et inhibiteurs de pompes d'efflux pour lutter contre les bactéries pathogènes
JP2019515025A (ja) 2016-04-04 2019-06-06 ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー トポイソメラーゼ毒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3103403A (en) * 1963-09-10 Dyeing of polyester fibers with com-
US2980690A (en) * 1957-08-30 1961-04-18 Ciba Pharm Prod Inc New basically substituted benzylbenzimidazoles
US3072661A (en) * 1960-08-24 1963-01-08 Interchem Corp New process for improved bis-imidazole vat dyestuff pigments
US3133056A (en) * 1961-05-15 1964-05-12 May & Baker Ltd N-phenylpiperazine derivatives of tetrahydrobenzodiazepines
NL291735A (fr) * 1962-04-21
NL135043C (fr) * 1963-10-11
GB1122988A (en) * 1964-10-22 1968-08-07 Fisons Pest Control Ltd Benzimidazole derivatives
US3336191A (en) * 1966-03-11 1967-08-15 Smith Kline French Lab Anthelmintic 2-amidobenzimidazoles
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines

Also Published As

Publication number Publication date
GB1186723A (en) 1970-04-02
FR6681M (fr) 1969-02-03
NL6704539A (fr) 1967-10-02
DE1670684A1 (de) 1970-12-03
FR1519964A (fr) 1968-04-05
BE696499A (fr) 1967-10-03
CH533124A (de) 1973-01-31
CH525902A (de) 1972-07-31
MY7100120A (en) 1971-12-31
US3538097A (en) 1970-11-03

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