OA11841A - 2-Aminopyridines containing fused ring substituents. - Google Patents

2-Aminopyridines containing fused ring substituents. Download PDF

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Publication number
OA11841A
OA11841A OA1200100224A OA1200100224A OA11841A OA 11841 A OA11841 A OA 11841A OA 1200100224 A OA1200100224 A OA 1200100224A OA 1200100224 A OA1200100224 A OA 1200100224A OA 11841 A OA11841 A OA 11841A
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group
disorder
disorders
ring
alkyl
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Application number
OA1200100224A
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English (en)
Inventor
Lowe John Adams Iii
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Pfizer Prod Inc
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Publication of OA11841A publication Critical patent/OA11841A/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
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OA1200100224A 1999-02-25 2000-02-02 2-Aminopyridines containing fused ring substituents. OA11841A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12159799P 1999-02-25 1999-02-25

Publications (1)

Publication Number Publication Date
OA11841A true OA11841A (en) 2005-08-22

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ID=22397690

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OA1200100224A OA11841A (en) 1999-02-25 2000-02-02 2-Aminopyridines containing fused ring substituents.

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US (2) US6211208B1 (id)
EP (1) EP1155000B1 (id)
JP (1) JP3825636B2 (id)
KR (1) KR20010114213A (id)
CN (1) CN1341099A (id)
AP (1) AP2001002251A0 (id)
AR (1) AR018979A1 (id)
AT (1) ATE245143T1 (id)
AU (1) AU767593B2 (id)
BG (1) BG105855A (id)
BR (1) BR0008569A (id)
CA (1) CA2364719C (id)
CO (1) CO5160241A1 (id)
CR (1) CR6438A (id)
CZ (1) CZ20013036A3 (id)
DE (1) DE60003893T2 (id)
DK (1) DK1155000T3 (id)
DZ (1) DZ3017A1 (id)
EA (1) EA003941B1 (id)
EE (1) EE200100454A (id)
ES (1) ES2200813T3 (id)
GT (1) GT200000021A (id)
HN (1) HN2000000016A (id)
HR (1) HRP20010597A2 (id)
HU (1) HUP0200163A3 (id)
ID (1) ID29892A (id)
IL (1) IL144308A0 (id)
IS (1) IS6005A (id)
MA (1) MA26721A1 (id)
MX (1) MXPA01008671A (id)
NO (1) NO20014095L (id)
NZ (1) NZ512912A (id)
OA (1) OA11841A (id)
PA (1) PA8490901A1 (id)
PE (1) PE20001482A1 (id)
PL (1) PL350219A1 (id)
PT (1) PT1155000E (id)
SK (1) SK12022001A3 (id)
SV (1) SV2002000026A (id)
TN (1) TNSN00034A1 (id)
TR (1) TR200102481T2 (id)
WO (1) WO2000050400A1 (id)
YU (1) YU58301A (id)
ZA (1) ZA200106974B (id)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) * 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
CN1341099A (zh) * 1999-02-25 2002-03-20 辉瑞产品公司 含有稠合环取代基的2-氨基吡啶
NZ521870A (en) 2000-03-31 2004-08-27 Euro Celtique S Aminopyridines and their use as anticonvulsants and sodium channel blockers
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
EP1567497B1 (en) * 2002-12-06 2009-09-23 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
WO2014138460A1 (en) * 2013-03-07 2014-09-12 Northwestern University 2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors
EP3215497A4 (en) 2014-11-04 2018-11-07 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
US10759791B2 (en) 2014-11-04 2020-09-01 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
US12213973B2 (en) 2021-10-18 2025-02-04 Northwestern University Bacterial nitric oxide synthase inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4515696A (en) * 1994-12-12 1996-07-03 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
JPH101435A (ja) * 1995-09-14 1998-01-06 Nippon Kayaku Co Ltd 2−アミノピリジン類を有効成分とする一酸化窒素合成酵素阻害剤
UA49006C2 (uk) * 1996-03-29 2002-09-16 Файзер Інк. Похідні 6-фенілпіридил-2-аміну, фармацевтична композиція, спосіб інгібування синтази оксиду нітрогену у ссавців та спосіб лікування
HN1997000027A (es) 1996-12-06 1997-06-05 Pfizer Prod Inc Derivados de 6-fenil piridil - 2 amina
WO1998034919A1 (en) * 1997-02-10 1998-08-13 Pfizer Products Inc. 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines
HN1998000118A (es) * 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.
HN1998000125A (es) * 1997-08-28 1999-02-09 Pfizer Prod Inc 2-aminopiridinas con sustituyentes alcoxi ramificados
HRP20000825A2 (en) * 1998-06-03 2001-12-31 Pfizer Prod Inc 2-aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors
CN1341099A (zh) * 1999-02-25 2002-03-20 辉瑞产品公司 含有稠合环取代基的2-氨基吡啶

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WO2000050400A1 (en) 2000-08-31
NZ512912A (en) 2003-07-25
TNSN00034A1 (fr) 2005-11-10
AU2124300A (en) 2000-09-14
PL350219A1 (en) 2002-11-18
YU58301A (sh) 2004-05-12
SK12022001A3 (sk) 2002-07-02
NO20014095L (no) 2001-10-24
DE60003893T2 (de) 2004-02-05
ATE245143T1 (de) 2003-08-15
ID29892A (id) 2001-10-18
MXPA01008671A (es) 2002-03-14
EP1155000A1 (en) 2001-11-21
CZ20013036A3 (cs) 2002-03-13
US6211208B1 (en) 2001-04-03
IS6005A (is) 2001-07-13
SV2002000026A (es) 2002-02-05
KR20010114213A (ko) 2001-12-31
EE200100454A (et) 2002-12-16
PE20001482A1 (es) 2001-01-03
AU767593B2 (en) 2003-11-20
CO5160241A1 (es) 2002-05-30
CN1341099A (zh) 2002-03-20
DE60003893D1 (de) 2003-08-21
IL144308A0 (en) 2002-05-23
MA26721A1 (fr) 2004-12-20
US20010014689A1 (en) 2001-08-16
BR0008569A (pt) 2002-01-22
HUP0200163A2 (en) 2002-06-29
AR018979A1 (es) 2001-12-12
ZA200106974B (en) 2002-10-14
NO20014095D0 (no) 2001-08-23
DK1155000T3 (da) 2003-10-13
CA2364719A1 (en) 2000-08-31
DZ3017A1 (fr) 2004-03-20
BG105855A (en) 2002-04-30
AP2001002251A0 (en) 2001-09-30
HUP0200163A3 (en) 2002-11-28
HN2000000016A (es) 2001-02-02
TR200102481T2 (tr) 2002-01-21
EA200100816A1 (ru) 2001-12-24
GT200000021A (es) 2001-08-17
PT1155000E (pt) 2003-10-31
CR6438A (es) 2004-02-23
HRP20010597A2 (en) 2002-08-31
EP1155000B1 (en) 2003-07-16
JP3825636B2 (ja) 2006-09-27
US6372768B2 (en) 2002-04-16
CA2364719C (en) 2006-07-04
PA8490901A1 (es) 2001-04-30
ES2200813T3 (es) 2004-03-16
JP2002537381A (ja) 2002-11-05
EA003941B1 (ru) 2003-10-30

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