OA12004A - Heterocyclic compounds inhibiting angiogenesis. - Google Patents

Heterocyclic compounds inhibiting angiogenesis. Download PDF

Info

Publication number: OA12004A
Authority: OA; OAPI
Prior art keywords: group; borrelidin; atom; general formula; nitrogen
Prior art date: 1999-08-02

Application number

OA1200200042A

Other languages

English (en)

Inventor

Gabor Ambrus

Andras Jeney

Nandor Makk

Aniko Tegdes

Ferenc Timar

Original Assignee

Ivax Drug Res Inst Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-02

Filing date

2000-08-02

Publication date

2006-04-18

2000-08-02 Application filed by Ivax Drug Res Inst Ltd filed Critical Ivax Drug Res Inst Ltd

2006-04-18 Publication of OA12004A publication Critical patent/OA12004A/en

Links

230000033115 angiogenesis Effects 0.000 title claims abstract description 16
230000002401 inhibitory effect Effects 0.000 title abstract description 17
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125000004433 nitrogen atom Chemical group N* 0.000 claims description 15
229910052757 nitrogen Inorganic materials 0.000 claims description 12
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QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 6
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OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
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239000010773 plant oil Substances 0.000 description 1
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HDOUGSFASVGDCS-UHFFFAOYSA-N pyridin-3-ylmethanamine Chemical compound NCC1=CC=CN=C1 HDOUGSFASVGDCS-UHFFFAOYSA-N 0.000 description 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
125000000714 pyrimidinyl group Chemical group 0.000 description 1
125000000168 pyrrolyl group Chemical group 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Ophthalmology & Optometry (AREA)
Dermatology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)

OA1200200042A 1999-08-02 2000-08-02 Heterocyclic compounds inhibiting angiogenesis. OA12004A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU9902628A HUP9902628A3 (en)	1999-08-02	1999-08-02	Angiogenesis inhibiting borrelidin derivatives, their use and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
OA12004A true OA12004A (en)	2006-04-18

Family

ID=89998954

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200200042A OA12004A (en)	1999-08-02	2000-08-02	Heterocyclic compounds inhibiting angiogenesis.

Country Status (32)

Country	Link
US (1)	US6815465B1 (de)
EP (1)	EP1206462B1 (de)
JP (1)	JP2003506366A (de)
KR (1)	KR20020068495A (de)
CN (1)	CN1243746C (de)
AP (1)	AP1383A (de)
AT (1)	ATE241611T1 (de)
AU (1)	AU772206B2 (de)
BG (1)	BG106373A (de)
BR (1)	BR0012968A (de)
CA (1)	CA2378176A1 (de)
CZ (1)	CZ2002405A3 (de)
DE (1)	DE60003045T2 (de)
DK (1)	DK1206462T3 (de)
ES (1)	ES2200900T3 (de)
HK (1)	HK1048995B (de)
HR (1)	HRP20020103B1 (de)
HU (1)	HUP9902628A3 (de)
IL (1)	IL147904A (de)
IS (1)	IS2137B (de)
MX (1)	MXPA02001117A (de)
NO (1)	NO20020485L (de)
NZ (1)	NZ517422A (de)
OA (1)	OA12004A (de)
PL (1)	PL354281A1 (de)
PT (1)	PT1206462E (de)
RU (1)	RU2247723C2 (de)
SK (1)	SK1822002A3 (de)
UA (1)	UA74341C2 (de)
WO (1)	WO2001009113A2 (de)
YU (1)	YU7302A (de)
ZA (1)	ZA200200838B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6376514B1 (en)	2000-10-17	2002-04-23	The Procter & Gamble Co.	Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US6693099B2 (en) *	2000-10-17	2004-02-17	The Procter & Gamble Company	Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
AU2003218110A1 (en)	2002-03-12	2003-09-29	Bristol-Myers Squibb Company	C3-cyano epothilone derivatives
GB0230217D0 (en) *	2002-12-27	2003-02-05	Biotica Tech Ltd	Borrelidin-producing polyketide synthase and its uses
US8440217B1 (en)	2005-06-15	2013-05-14	Mawaheb M. EL-Naggar	Method and system with contact lens product for treating and preventing adverse eye conditions
GB0609981D0 (en) *	2006-05-19	2006-06-28	Biotica Tech Ltd	Novel compounds
GB0713563D0 (en) *	2007-07-13	2007-08-22	Biotica Tech Ltd	Methods of screening for anti-angiogenic compounds
ES2423932T3 (es) *	2007-08-27	2013-09-25	Basf Se	Compuestos de pirazol para controlar plagas de invertebrados
DE102008014077A1 (de)	2008-03-13	2009-09-17	Discovery Partner International Gmbh	Borrelidin-Derivate
WO2009141786A2 (en) *	2008-05-21	2009-11-26	Piramal Life Sciences Limited	Anti-inflammatory compounds
DK3034522T3 (en)	2014-12-15	2019-04-15	Borealis Ag	Use of a polypropylene composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2099334C1 (ru) *	1986-06-06	1997-12-20	Американ Цианамид Компани	Макролидные соединения, композиция, обладающая антибиотической активностью, ветеринарная композиция, инсектоакарицидонематоцидная композиция и способ уничтожения насекомых и/или клещей, нематод
JPH08173176A (ja)	1994-12-22	1996-07-09	Mercian Corp	血管新生阻害剤
JP3786461B2 (ja)	1996-02-22	2006-06-14	メルシャン株式会社	新生理活性物質

1999
- 1999-08-02 HU HU9902628A patent/HUP9902628A3/hu unknown
2000
- 2000-08-02 HK HK03101165.4A patent/HK1048995B/zh not_active IP Right Cessation
- 2000-08-02 CN CNB008123578A patent/CN1243746C/zh not_active Expired - Fee Related
- 2000-08-02 JP JP2001514316A patent/JP2003506366A/ja not_active Withdrawn
- 2000-08-02 KR KR1020027001484A patent/KR20020068495A/ko not_active Ceased
- 2000-08-02 AT AT00949831T patent/ATE241611T1/de not_active IP Right Cessation
- 2000-08-02 BR BR0012968-2A patent/BR0012968A/pt not_active IP Right Cessation
- 2000-08-02 IL IL14790400A patent/IL147904A/xx not_active IP Right Cessation
- 2000-08-02 AU AU63090/00A patent/AU772206B2/en not_active Ceased
- 2000-08-02 HR HR20020103A patent/HRP20020103B1/xx not_active IP Right Cessation
- 2000-08-02 PL PL00354281A patent/PL354281A1/xx not_active Application Discontinuation
- 2000-08-02 DE DE60003045T patent/DE60003045T2/de not_active Expired - Fee Related
- 2000-08-02 UA UA2002010814A patent/UA74341C2/uk unknown
- 2000-08-02 YU YU7302A patent/YU7302A/sh unknown
- 2000-08-02 CZ CZ2002405A patent/CZ2002405A3/cs unknown
- 2000-08-02 CA CA002378176A patent/CA2378176A1/en not_active Abandoned
- 2000-08-02 NZ NZ517422A patent/NZ517422A/en unknown
- 2000-08-02 RU RU2002105518/04A patent/RU2247723C2/ru not_active IP Right Cessation
- 2000-08-02 SK SK182-2002A patent/SK1822002A3/sk unknown
- 2000-08-02 DK DK00949831T patent/DK1206462T3/da active
- 2000-08-02 OA OA1200200042A patent/OA12004A/en unknown
- 2000-08-02 WO PCT/HU2000/000088 patent/WO2001009113A2/en not_active Ceased
- 2000-08-02 PT PT00949831T patent/PT1206462E/pt unknown
- 2000-08-02 MX MXPA02001117A patent/MXPA02001117A/es active IP Right Grant
- 2000-08-02 AP APAP/P/2002/002413A patent/AP1383A/en active
- 2000-08-02 US US10/048,659 patent/US6815465B1/en not_active Expired - Fee Related
- 2000-08-02 EP EP00949831A patent/EP1206462B1/de not_active Expired - Lifetime
- 2000-08-02 ES ES00949831T patent/ES2200900T3/es not_active Expired - Lifetime
2002
- 2002-01-30 ZA ZA200200838A patent/ZA200200838B/en unknown
- 2002-01-30 NO NO20020485A patent/NO20020485L/no not_active Application Discontinuation
- 2002-01-31 BG BG06373A patent/BG106373A/xx unknown
- 2002-02-01 IS IS6258A patent/IS2137B/xx unknown

Also Published As

Publication number	Publication date
EP1206462A2 (de)	2002-05-22
AP1383A (en)	2005-04-05
EP1206462B1 (de)	2003-05-28
HRP20020103A2 (en)	2004-02-29
CN1243746C (zh)	2006-03-01
IL147904A0 (en)	2002-08-14
UA74341C2 (uk)	2005-12-15
BG106373A (en)	2002-09-30
AP2002002413A0 (en)	2002-03-31
IS2137B (is)	2006-08-14
DK1206462T3 (da)	2003-09-29
YU7302A (sh)	2004-09-03
CZ2002405A3 (cs)	2002-07-17
HU9902628D0 (en)	1999-10-28
JP2003506366A (ja)	2003-02-18
HK1048995A1 (en)	2003-04-25
PT1206462E (pt)	2003-10-31
HK1048995B (zh)	2006-07-21
IL147904A (en)	2005-09-25
ZA200200838B (en)	2003-08-27
IS6258A (is)	2002-02-01
CN1372556A (zh)	2002-10-02
NO20020485L (no)	2002-03-21
ATE241611T1 (de)	2003-06-15
AU772206B2 (en)	2004-04-22
AU6309000A (en)	2001-02-19
HRP20020103B1 (en)	2005-06-30
BR0012968A (pt)	2002-05-14
RU2247723C2 (ru)	2005-03-10
DE60003045D1 (de)	2003-07-03
HUP9902628A3 (en)	2001-07-30
MXPA02001117A (es)	2003-08-20
PL354281A1 (en)	2003-12-29
CA2378176A1 (en)	2001-02-08
KR20020068495A (ko)	2002-08-27
WO2001009113A2 (en)	2001-02-08
HUP9902628A2 (hu)	2001-05-28
DE60003045T2 (de)	2004-04-01
NO20020485D0 (no)	2002-01-30
WO2001009113A3 (en)	2001-06-14
US6815465B1 (en)	2004-11-09
SK1822002A3 (en)	2002-08-06
NZ517422A (en)	2005-02-25
ES2200900T3 (es)	2004-03-16

Publication	Publication Date	Title
EP2024335B1 (de)	2010-06-23	Neue imidazolderivate, ihre herstellung und ihre verwendung als medizin
US6815465B1 (en)	2004-11-09	Heterocyclic compounds inhibiting angiogenesis
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