OA12539A - Benzimidazole and pyridylimidazole derivatives as ligands for GABA receptors. - Google Patents

Benzimidazole and pyridylimidazole derivatives as ligands for GABA receptors. Download PDF

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Publication number
OA12539A
OA12539A OA1200300157A OA1200300157A OA12539A OA 12539 A OA12539 A OA 12539A OA 1200300157 A OA1200300157 A OA 1200300157A OA 1200300157 A OA1200300157 A OA 1200300157A OA 12539 A OA12539 A OA 12539A
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OA
OAPI
Prior art keywords
alkyl
compound
cycloalkyl
alkoxy
hydrogen
Prior art date
Application number
OA1200300157A
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English (en)
Inventor
Guiying Li
John M Peterson
Pamela Albaugh
Kevin S Currie
Guolin Cai
Linda M Gustavson
Kyungae Lee
Alan Hutchison
Vinod Singh
George D Maynard
Jun Yuan
Xie Ling Hong
Manuka Ghosh
Nian Liu
George P Luke
Scott Mitchell
Martin Patrick Allen
Spiros Liras
Original Assignee
Neurogen Corp
Pfizer
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Application filed by Neurogen Corp, Pfizer filed Critical Neurogen Corp
Publication of OA12539A publication Critical patent/OA12539A/en

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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

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  • Organic Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
OA1200300157A 2000-12-21 2001-12-21 Benzimidazole and pyridylimidazole derivatives as ligands for GABA receptors. OA12539A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25749200P 2000-12-21 2000-12-21

Publications (1)

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OA12539A true OA12539A (en) 2006-06-05

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OA1200300157A OA12539A (en) 2000-12-21 2001-12-21 Benzimidazole and pyridylimidazole derivatives as ligands for GABA receptors.

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EP (1) EP1368342B3 (cs)
JP (1) JP2004536782A (cs)
KR (1) KR100854174B1 (cs)
CN (1) CN1553909A (cs)
AP (1) AP1503A (cs)
AR (1) AR035774A1 (cs)
AT (1) ATE304008T1 (cs)
AU (2) AU3276802A (cs)
BG (1) BG107899A (cs)
BR (1) BR0116385A (cs)
CA (1) CA2431592A1 (cs)
CO (1) CO5390086A1 (cs)
CZ (1) CZ20031676A3 (cs)
DE (1) DE60113302T2 (cs)
EA (1) EA007157B1 (cs)
EC (1) ECSP034656A (cs)
EE (1) EE05108B1 (cs)
EG (1) EG24590A (cs)
ES (1) ES2256325T3 (cs)
HR (1) HRP20030483A9 (cs)
HU (1) HUP0303849A3 (cs)
IL (1) IL156294A0 (cs)
IS (1) IS6855A (cs)
MA (1) MA26974A1 (cs)
MX (1) MXPA03005493A (cs)
MY (1) MY141733A (cs)
NO (1) NO326558B1 (cs)
NZ (1) NZ526330A (cs)
OA (1) OA12539A (cs)
PA (1) PA8535601A1 (cs)
PE (1) PE20020720A1 (cs)
PL (1) PL366243A1 (cs)
SK (1) SK7672003A3 (cs)
TW (1) TWI304402B (cs)
UA (1) UA75902C2 (cs)
UY (1) UY27095A1 (cs)
WO (1) WO2002050062A2 (cs)
YU (1) YU51703A (cs)
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