OA12698A - N-(3-amino-2-hydroxy-propyl)substituted alkylamidecompounds. - Google Patents

N-(3-amino-2-hydroxy-propyl)substituted alkylamidecompounds. Download PDF

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Publication number
OA12698A
OA12698A OA1200400006A OA1200400006A OA12698A OA 12698 A OA12698 A OA 12698A OA 1200400006 A OA1200400006 A OA 1200400006A OA 1200400006 A OA1200400006 A OA 1200400006A OA 12698 A OA12698 A OA 12698A
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OA
OAPI
Prior art keywords
amino
difluorobenzyl
hydroxypropyl
ethylbenzyl
acetamide
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OA1200400006A
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English (en)
Inventor
Andrea Gailunas
John Mickelson
Ruth Tenbrink
John A Tucker
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Elan Pharm Inc
Upjohn Co
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Application filed by Elan Pharm Inc, Upjohn Co filed Critical Elan Pharm Inc
Publication of OA12698A publication Critical patent/OA12698A/en

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    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/40—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

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OA1200400006A 2001-07-11 2002-07-11 N-(3-amino-2-hydroxy-propyl)substituted alkylamidecompounds. OA12698A (en)

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MXPA04000334A (es) 2004-09-28
US20100048590A1 (en) 2010-02-25
GEP20074221B (en) 2007-10-25
EA200400162A1 (ru) 2005-06-30
HRP20040069A2 (en) 2005-02-28
US7589094B2 (en) 2009-09-15
EP1409450A1 (de) 2004-04-21
WO2003006423A1 (en) 2003-01-23
JP4278511B2 (ja) 2009-06-17
AU2002320490B2 (en) 2008-10-02
NO20040139L (no) 2004-02-26
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ATE451348T1 (de) 2009-12-15
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