OA12718A - Benzamide and heteroarylamide as P2X7 receptor antagonists. - Google Patents

Benzamide and heteroarylamide as P2X7 receptor antagonists. Download PDF

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Publication number
OA12718A
OA12718A OA1200400127A OA1200400127A OA12718A OA 12718 A OA12718 A OA 12718A OA 1200400127 A OA1200400127 A OA 1200400127A OA 1200400127 A OA1200400127 A OA 1200400127A OA 12718 A OA12718 A OA 12718A
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OA
OAPI
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alkyl
chloro
crc4
group
dihydro
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OA1200400127A
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English (en)
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Allen Jacob Duplantier
Chakrapani Subramanyam
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Pfizer Prod Inc
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Publication of OA12718A publication Critical patent/OA12718A/en

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    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
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OA1200400127A 2001-11-12 2002-11-04 Benzamide and heteroarylamide as P2X7 receptor antagonists. OA12718A (en)

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PA8557501A1 (es) * 2001-11-12 2003-06-30 Pfizer Prod Inc Benzamida, heteroarilamida y amidas inversas
PA8591801A1 (es) * 2002-12-31 2004-07-26 Pfizer Prod Inc Inhibidores benzamidicos del receptor p2x7.
BR0317844A (pt) * 2002-12-31 2005-12-06 Pfizer Prod Inc Inibidores de benzamida do receptor p2x7
US7071223B1 (en) 2002-12-31 2006-07-04 Pfizer, Inc. Benzamide inhibitors of the P2X7 receptor
SE0300480D0 (sv) 2003-02-21 2003-02-21 Astrazeneca Ab Novel compounds
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