OA12739A - Platinum derivative pharmaceutical formulations. - Google Patents

Platinum derivative pharmaceutical formulations. Download PDF

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Publication number
OA12739A
OA12739A OA1200400165A OA1200400165A OA12739A OA 12739 A OA12739 A OA 12739A OA 1200400165 A OA1200400165 A OA 1200400165A OA 1200400165 A OA1200400165 A OA 1200400165A OA 12739 A OA12739 A OA 12739A
Authority
OA
OAPI
Prior art keywords
formulation
oxaliplatin
lactic acid
ranges
pharmaceutically acceptable
Prior art date
Application number
OA1200400165A
Other languages
English (en)
Inventor
Cristina Ciocca
Sara Lauria
Alessandro Martini
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21744006&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA12739(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Publication of OA12739A publication Critical patent/OA12739A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
OA1200400165A 2001-12-06 2002-11-22 Platinum derivative pharmaceutical formulations. OA12739A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/010,122 US6476068B1 (en) 2001-12-06 2001-12-06 Platinum derivative pharmaceutical formulations

Publications (1)

Publication Number Publication Date
OA12739A true OA12739A (en) 2006-06-30

Family

ID=21744006

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200400165A OA12739A (en) 2001-12-06 2002-11-22 Platinum derivative pharmaceutical formulations.

Country Status (41)

Country Link
US (3) US6476068B1 (de)
EP (1) EP1453517B1 (de)
JP (1) JP2005515202A (de)
KR (1) KR100941210B1 (de)
CN (1) CN100540006C (de)
AP (1) AP1760A (de)
AR (1) AR037629A1 (de)
AT (1) ATE317260T1 (de)
AU (1) AU2002352105B2 (de)
BR (1) BR0214757A (de)
CA (1) CA2468916C (de)
CO (1) CO5580776A2 (de)
CR (1) CR7362A (de)
CY (1) CY1105608T1 (de)
DE (1) DE60209145T2 (de)
DK (1) DK1453517T3 (de)
EA (1) EA008090B1 (de)
EC (1) ECSP045140A (de)
ES (1) ES2258661T3 (de)
GE (1) GEP20063895B (de)
HR (1) HRP20040514A2 (de)
HU (1) HUP0402217A3 (de)
IL (2) IL162348A0 (de)
IS (1) IS2580B (de)
MA (1) MA27153A1 (de)
ME (1) MEP10408A (de)
MX (1) MXPA04005423A (de)
MY (1) MY134422A (de)
NO (1) NO330159B1 (de)
NZ (1) NZ533383A (de)
OA (1) OA12739A (de)
PL (1) PL206755B1 (de)
PT (1) PT1453517E (de)
RO (1) RO121509B1 (de)
RS (1) RS50360B (de)
SI (1) SI21493A (de)
TN (1) TNSN04104A1 (de)
TW (1) TW200409640A (de)
UA (1) UA77728C2 (de)
WO (1) WO2003047587A1 (de)
ZA (1) ZA200404525B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004505A1 (en) * 2001-07-02 2003-01-16 Debiopharm S.A. Oxaliplatin active substance with a very low content of oxalic acid
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
CN101022790A (zh) * 2003-08-28 2007-08-22 梅恩医药有限公司 含有酸的奥沙利铂制剂
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
WO2005047244A2 (en) * 2003-11-07 2005-05-26 Chiron Corporation Inhibition of fgfr3 and treatment of multiple myeloma
RU2273475C2 (ru) * 2004-04-06 2006-04-10 Государственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" (ГУ СВ ПО СибГМУ) Способ лечения диссеминированного колоректального рака
US7795205B2 (en) * 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
RS52668B (sr) * 2004-06-09 2013-06-28 Taiho Pharmaceutical Co. Ltd. Pojačivač antitumornog efekta, antitumorno sredstvo i postupak lečenja kancera
JP2007505165A (ja) * 2004-07-12 2007-03-08 シコール インコーポレイティド シス−ジヨード−（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ｉｉ）錯体及び高純度オキサリプラチンの調製方法
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
CN1311818C (zh) * 2004-11-22 2007-04-25 山东蓝金生物工程有限公司 一种抗实体肿瘤的药物组合物
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
AU2005329764B2 (en) * 2005-03-28 2010-08-12 Dabur Pharma Ltd. Stable pharmaceutical compositions of platinum (II) antitumour agents
CN101222850B (zh) * 2005-05-13 2012-10-03 诺瓦提斯公司 治疗对药物有抗性的癌症的方法
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (en) * 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
PL1957074T3 (pl) * 2005-11-29 2014-08-29 Novartis Ag Preparaty chinolinonów
US20090076139A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched oxalplatin
EP2152239A1 (de) * 2007-11-12 2010-02-17 Intas Pharmaceuticals Limited Stabile oxaliplatinzusammensetzung zur parenteralen verabreichung
EP2259776A4 (de) * 2008-02-29 2011-03-16 Eagle Pharmaceuticals Inc Gebrauchsfertige topotecan-lösungen
TW201021855A (en) * 2008-11-13 2010-06-16 Taigen Biotechnology Co Ltd Lyophilization formulation
CA2774669C (en) 2009-09-21 2017-12-19 Jw Pharmaceutical Corporation Oxaliplatin nanoparticles and method for preparing same
US9387152B2 (en) 2010-06-28 2016-07-12 The General Hospital Corporation Blood substitutes and uses thereof
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
WO2014015016A1 (en) 2012-07-18 2014-01-23 Onyx Therapeutics, Inc. Liposomal compositions of epoxyketone-based proteasome inhibitors
JP5929607B2 (ja) * 2012-08-06 2016-06-08 ニプロ株式会社 オキサリプラチン製剤
CN102885765B (zh) * 2012-10-25 2013-11-06 哈药集团生物工程有限公司 一种盐酸伊立替康注射液及其制备方法
US10098813B2 (en) * 2014-09-03 2018-10-16 Sun Pharmaceutical Industries Limited Perfusion dosage form
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
FI4011377T3 (fi) * 2015-02-13 2025-01-07 Sun Pharmaceutical Ind Ltd Suonensisäinen infuusioannosmuoto sisältäen pemetreksediä
KR102293907B1 (ko) 2015-06-30 2021-08-26 한미약품 주식회사 이리노테칸 함유 경구용 고형제제 및 그 제조방법
PL3413862T3 (pl) 2016-02-09 2024-03-18 Sun Pharmaceutical Industries Ltd. Układ perfuzyjny
EP3538546B1 (de) 2016-11-14 2025-01-08 Novartis AG Zusammensetzungen, methoden und therapeutische verwendungen des fusogenen proteins minion
CN120241688A (zh) 2018-01-12 2025-07-04 麦提麦迪制药有限公司 乳酸钙在制备用于治疗疾病的药物组合物、食物或营养组合物中的用途
KR101998246B1 (ko) 2018-08-22 2019-07-10 주식회사 메타파인즈 금속이온에 결합된 이온화합물을 포함하는 암 치료용 약학 조성물

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
NZ245112A (en) 1991-11-15 1995-07-26 Smithkline Beecham Corp Pharmaceutical composition comprising a camptothecin analog and a platinum coordination compound
JPH0776230B2 (ja) 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
JPH06287021A (ja) 1992-04-22 1994-10-11 Tanaka Kikinzoku Kogyo Kk 光学活性な白金錯化合物の光学的分割方法
JP2673331B2 (ja) 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
AU5416394A (en) 1992-11-24 1994-06-22 Debiopharm S.A. Cisplatinum/oxaliplatinum combination
CA2149150C (en) * 1992-11-27 2000-08-01 David R. Carver Injectable taxol composition with improved stability
JP3025602B2 (ja) 1993-05-21 2000-03-27 デビオファーム エス．アー． 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
DE69519300T2 (de) 1994-08-08 2001-05-31 Debiopharm S.A., Lausanne Stabiles arzneimittel enthaltend oxaliplatin
EP0715854B1 (de) 1994-11-11 2003-09-10 Debiopharm S.A. Karzinostatische Zusammensetzungen, welche Cis-Oxaliplatin und eine oder mehrere andere verträgliche Karzinostatika enthalten
US5919816A (en) 1994-11-14 1999-07-06 Bionumerik Pharmaceuticals, Inc. Formulations and methods of reducing toxicity of antineoplastic agents
EP0812852B1 (de) * 1995-02-28 2003-04-23 Yoshinori Kidani Platin(iv)-komplexe, verfahren zu ihrer herstellung und sie enthaltende carcinostatische mittel
US5776959A (en) 1995-06-05 1998-07-07 Washington University Anticonvulsant and anxiolytic lactam and thiolactam derivatives
JP3154399B2 (ja) 1996-07-04 2001-04-09 デビオファーム エス．アー． 白金化合物の製造方法
DE69713763T2 (de) * 1996-03-11 2003-03-13 Yoshinori Kidani Binukleare platinkomplexe, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die diese komplexe enthalten
PT929293E (pt) 1996-08-23 2004-03-31 Sequus Pharm Inc Lipossomas contendo um composto de cisplatina
US6056973A (en) 1996-10-11 2000-05-02 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method of preparation
IL131008A (en) 1997-02-05 2003-06-24 Upjohn Co Lipid complexes and liposomes of highly insoluble platinum complex dicarboxylate
WO1998039009A1 (en) 1997-03-07 1998-09-11 Sanofi Pharmaceuticals, Inc. Method of treating a tumor
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
ES2178474T3 (es) 1998-10-14 2002-12-16 Debiopharm Sa Acondicionamiento de una preparacion de oxaliplatino.
DK1207875T3 (da) 1999-08-30 2004-01-19 Debiopharm Sa Farmaceutisk stabilt oxaliplatin-præparat til parenteral administration
WO2001066102A2 (en) 2000-03-08 2001-09-13 Bristol-Myers Squibb Company Oral dosage form for administration of the combination of tegafur, uracil, folinic acid, and oxaliplatin and method of using the same
SE0003026D0 (sv) * 2000-08-25 2000-08-25 Kerstin Sunnerheim Use for conifer sapling protection

Also Published As

Publication number Publication date
US6476068B1 (en) 2002-11-05
IS7298A (is) 2004-06-03
HUP0402217A3 (en) 2005-11-28
HRP20040514A2 (en) 2004-10-31
JP2005515202A (ja) 2005-05-26
AP2004003055A0 (en) 2004-06-30
CY1105608T1 (el) 2010-12-22
CN100540006C (zh) 2009-09-16
RO121509B1 (ro) 2007-10-30
SI21493A (sl) 2004-12-31
IL162348A0 (en) 2005-11-20
NO20042842L (no) 2004-07-05
GEP20063895B (en) 2006-08-10
EP1453517A1 (de) 2004-09-08
DE60209145T2 (de) 2006-10-26
KR100941210B1 (ko) 2010-02-10
WO2003047587A1 (en) 2003-06-12
CA2468916C (en) 2009-01-20
US6673805B2 (en) 2004-01-06
AR037629A1 (es) 2004-11-17
MXPA04005423A (es) 2004-10-11
YU59704A (sh) 2006-08-17
KR20050058278A (ko) 2005-06-16
EA200400777A1 (ru) 2004-12-30
CN1612737A (zh) 2005-05-04
ATE317260T1 (de) 2006-02-15
ZA200404525B (en) 2005-08-15
MY134422A (en) 2007-12-31
NO330159B1 (no) 2011-02-28
RS50360B (sr) 2009-11-10
MEP10408A (en) 2011-02-10
US20030109515A1 (en) 2003-06-12
EP1453517B1 (de) 2006-02-08
ECSP045140A (es) 2004-08-27
MA27153A1 (fr) 2005-01-03
UA77728C2 (en) 2007-01-15
IL162348A (en) 2010-11-30
AP1760A (en) 2007-07-18
PL206755B1 (pl) 2010-09-30
IS2580B (is) 2010-02-15
EA008090B1 (ru) 2007-02-27
CR7362A (es) 2009-02-12
HUP0402217A2 (hu) 2005-01-28
BR0214757A (pt) 2004-09-14
CA2468916A1 (en) 2003-06-12
AU2002352105B2 (en) 2009-12-03
US20030109514A1 (en) 2003-06-12
ES2258661T3 (es) 2006-09-01
NZ533383A (en) 2007-02-23
PL370254A1 (en) 2005-05-16
CO5580776A2 (es) 2005-11-30
HK1072002A1 (zh) 2005-08-12
AU2002352105A1 (en) 2003-06-17
PT1453517E (pt) 2006-06-30
DE60209145D1 (de) 2006-04-20
TNSN04104A1 (fr) 2006-06-01
DK1453517T3 (da) 2006-06-19
TW200409640A (en) 2004-06-16

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