OA13154A - Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them. - Google Patents

Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them. Download PDF

Info

Publication number: OA13154A
Authority: OA; OAPI
Prior art keywords: substituted; unsubstituted; dibenzo; carboxamide; furan
Prior art date: 2003-04-11

Application number

OA1200500280A

Other languages

English (en)

Inventor

Laxmikant Atmaram Gharat

Balasubramanian Gopalan

Usha Karaunakaran

Aftab Dawoodhai Lakdawala

Original Assignee

Glenmark Pharmaceuticals Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-11

Filing date

2004-02-11

Publication date

2006-12-13

2004-02-11 Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa

2006-12-13 Publication of OA13154A publication Critical patent/OA13154A/en

Links

208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims description 30
238000000034 method Methods 0.000 title claims description 26
230000002757 inflammatory effect Effects 0.000 title claims description 14
208000010668 atopic eczema Diseases 0.000 title claims description 4
239000008194 pharmaceutical composition Substances 0.000 title abstract description 11
150000002391 heterocyclic compounds Chemical class 0.000 title abstract description 8
230000008569 process Effects 0.000 title description 9
238000002360 preparation method Methods 0.000 title description 2
230000000172 allergic effect Effects 0.000 title 1
150000003839 salts Chemical class 0.000 claims abstract description 37
150000001204 N-oxides Chemical class 0.000 claims abstract description 16
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims abstract description 13
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150000001875 compounds Chemical class 0.000 claims description 158
-1 -OH Chemical group 0.000 claims description 74
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IPEMCIBPDYCJLO-UHFFFAOYSA-N 5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]-n-(2,4,6-trimethoxyphenyl)furan-2-carboxamide Chemical compound COC1=CC(OC)=CC(OC)=C1NC(=O)C(O1)=CC=C1CC1=CC(C(CCC2(C)C)(C)C)=C2C=C1C IPEMCIBPDYCJLO-UHFFFAOYSA-N 0.000 claims description 19
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Classifications

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- C07—ORGANIC CHEMISTRY
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- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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OA1200500280A 2003-04-11 2004-02-11 Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them. OA13154A (en)

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- 2004-11-02 UA UAA200510680A patent/UA79558C2/uk unknown
2005
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2006
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Also Published As

Publication number	Publication date
EP1620429B1 (de)	2009-04-01
GEP20084526B (en)	2008-11-10
MA27801A1 (fr)	2006-03-01
US20050027129A1 (en)	2005-02-03
US7223789B2 (en)	2007-05-29
AP2008A (en)	2009-06-29
EA200501617A1 (ru)	2006-04-28
TNSN05252A1 (en)	2007-07-10
AU2004228453B2 (en)	2010-08-19
DE602004020332D1 (de)	2009-05-14
ATE427308T1 (de)	2009-04-15
NO20055316D0 (no)	2005-11-10
EP1620429A1 (de)	2006-02-01
CA2522023A1 (en)	2004-10-21
JP2006522789A (ja)	2006-10-05
ES2320888T3 (es)	2009-05-29
DK1620429T3 (da)	2009-05-18
HRP20050944A2 (en)	2006-02-28
AP2005003424A0 (en)	2005-12-31
TW200508212A (en)	2005-03-01
MY136516A (en)	2008-10-31
MXPA05010948A (es)	2006-05-31
EA010634B1 (ru)	2008-10-30
AR043199A1 (es)	2005-07-20
KR20060017494A (ko)	2006-02-23
CL2004000526A1 (es)	2005-03-18
CO5700824A2 (es)	2006-11-30
SI1620429T1 (sl)	2009-08-31
US7384962B2 (en)	2008-06-10
NO20055316L (no)	2006-01-11
US7393846B2 (en)	2008-07-01
PL378813A1 (pl)	2006-05-29
IS8123A (is)	2005-11-10
UA79558C2 (en)	2007-06-25
NZ542882A (en)	2007-10-26
US20070105855A1 (en)	2007-05-10
PT1620429E (pt)	2009-04-28
ZA200508240B (en)	2006-05-31
AU2004228453A1 (en)	2004-10-21
US20090182143A1 (en)	2009-07-16
BRPI0409747A (pt)	2006-05-09
CN1829711A (zh)	2006-09-06
CN1829711B (zh)	2010-06-16
WO2004089940A1 (en)	2004-10-21
US20070105854A1 (en)	2007-05-10

Publication	Publication Date	Title
OA13154A (en)	2006-12-13	Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them.
EP1554262B1 (de)	2007-12-05	Tricyclische verbindungen zur behandlung von entzündlichen- und allergischen erkrankungen: verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
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WO2004111044A1 (en)	2004-12-23	Tricyclic compounds useful for the treatment of inflammatory and allergic disorders:process for their preparation
WO2006011024A2 (en)	2006-02-02	New tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
NO177262B (no)	1995-05-08	Analogifremgangsmåte for fremstilling av terapeutisk aktive, O-substituerte oximer
AU2004312284B2 (en)	2010-08-05	Non-nucleotide reverse transcriptase inhibitors
KR20060021896A (ko)	2006-03-08	세로토닌 재흡수 저해제 형태의 인돌 유도체
WO2002072567A2 (en)	2002-09-19	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
WO2006040650A1 (en)	2006-04-20	4-methoxyacridine-1-carboxamide derivatives and the phenazine and oxanthrene analogs as pde4-inhibitors for the treatment of asthma and chronic pulmonary disease (copd)
WO2006051390A1 (en)	2006-05-18	Heterocyclic compounds useful for the treatment of inflammatory and allergic disorders, pharmaceutical compositions containing them, and methods of preparing them
HK1101400B (en)	2011-03-25	Non-nucleotide reverse transcriptase inhibitors