IS8123A - Ný heteróhringlaga efnasambönd sem eru gagnleg í meðhöndlun á bólgu- og ofnæmissjúkdómum; aðferðir til að framleiða þau og lyfjablöndur sem innihaldaþau - Google Patents
Ný heteróhringlaga efnasambönd sem eru gagnleg í meðhöndlun á bólgu- og ofnæmissjúkdómum; aðferðir til að framleiða þau og lyfjablöndur sem innihaldaþauInfo
- Publication number
- IS8123A IS8123A IS8123A IS8123A IS8123A IS 8123 A IS8123 A IS 8123A IS 8123 A IS8123 A IS 8123A IS 8123 A IS8123 A IS 8123A IS 8123 A IS8123 A IS 8123A
- Authority
- IS
- Iceland
- Prior art keywords
- inflammatory
- producing
- treatment
- methods
- pharmaceutical preparations
- Prior art date
Links
- 208000026935 allergic disease Diseases 0.000 title 1
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 210000003097 mucus Anatomy 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN363MU2003 | 2003-04-11 | ||
| US51996703P | 2003-11-13 | 2003-11-13 | |
| PCT/IB2004/000355 WO2004089940A1 (en) | 2003-04-11 | 2004-02-11 | Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS8123A true IS8123A (is) | 2005-11-10 |
Family
ID=36947516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS8123A IS8123A (is) | 2003-04-11 | 2005-11-10 | Ný heteróhringlaga efnasambönd sem eru gagnleg í meðhöndlun á bólgu- og ofnæmissjúkdómum; aðferðir til að framleiða þau og lyfjablöndur sem innihaldaþau |
Country Status (34)
| Country | Link |
|---|---|
| US (4) | US7223789B2 (is) |
| EP (1) | EP1620429B1 (is) |
| JP (1) | JP2006522789A (is) |
| KR (1) | KR20060017494A (is) |
| CN (1) | CN1829711B (is) |
| AP (1) | AP2008A (is) |
| AR (1) | AR043199A1 (is) |
| AT (1) | ATE427308T1 (is) |
| AU (1) | AU2004228453B2 (is) |
| BR (1) | BRPI0409747A (is) |
| CA (1) | CA2522023A1 (is) |
| CL (1) | CL2004000526A1 (is) |
| CO (1) | CO5700824A2 (is) |
| DE (1) | DE602004020332D1 (is) |
| DK (1) | DK1620429T3 (is) |
| EA (1) | EA010634B1 (is) |
| ES (1) | ES2320888T3 (is) |
| GE (1) | GEP20084526B (is) |
| HR (1) | HRP20050944A2 (is) |
| IS (1) | IS8123A (is) |
| MA (1) | MA27801A1 (is) |
| MX (1) | MXPA05010948A (is) |
| MY (1) | MY136516A (is) |
| NO (1) | NO20055316L (is) |
| NZ (1) | NZ542882A (is) |
| OA (1) | OA13154A (is) |
| PL (1) | PL378813A1 (is) |
| PT (1) | PT1620429E (is) |
| SI (1) | SI1620429T1 (is) |
| TN (1) | TNSN05252A1 (is) |
| TW (1) | TW200508212A (is) |
| UA (1) | UA79558C2 (is) |
| WO (1) | WO2004089940A1 (is) |
| ZA (1) | ZA200508240B (is) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7238725B2 (en) * | 2002-10-23 | 2007-07-03 | Glenmark Pharmaceuticals Ltd. | Tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them |
| PL378813A1 (pl) * | 2003-04-11 | 2006-05-29 | Glenmark Pharmaceuticals S.A. | Nowe związki heterocykliczne przydatne w leczeniu stanów zapalnych i zaburzeń alergicznych: sposób ich wytwarzania i kompozycje farmaceutyczne zawierające te związki |
| MX2007004400A (es) | 2004-10-13 | 2007-06-19 | Glenmark Pharmaceuticals Sa | Procedimiento para la preparacion de n-(3,5-dicloropirid-a-il)-4- ifluorometoxi-8-metanosulfonamido-dibenzo [b,d] difuran-1-carboxamida. |
| WO2006051390A1 (en) * | 2004-11-10 | 2006-05-18 | Glenmark Pharmaceuticals S.A. | Heterocyclic compounds useful for the treatment of inflammatory and allergic disorders, pharmaceutical compositions containing them, and methods of preparing them |
| US7943634B2 (en) | 2004-12-17 | 2011-05-17 | Glenmark Pharmaceuticals S.A. | Substituted benzo[4,5]furo[3,2-c]pyridine derivatives as PDE 4 inhibitors |
| EA014956B1 (ru) * | 2004-12-17 | 2011-04-29 | ГЛЕНМАРК ФАРМАСЬЮТИКАЛС Эс.Эй. | Гетероциклические соединения, применяемые для лечения воспалительных и аллергических нарушений |
| US8119655B2 (en) * | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| RS53084B (sr) | 2006-07-05 | 2014-06-30 | Takeda Gmbh | Kombinacija inhibitora hmg-coa reduktaze rosuvastatina sa inhibitorom fosfodiesteraze 4, kao što je roflumilast, roflumilast-n-oksid za lečenje inflamatornih plućnih obolenja |
| WO2008005955A2 (en) * | 2006-07-06 | 2008-01-10 | Forest Laboratories Holdings Limited | Synthesis of heterocyclic compounds |
| CA2661850A1 (en) * | 2006-09-01 | 2008-03-06 | Kyorin Pharmaceutical Co., Ltd. | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same |
| WO2008029829A1 (en) * | 2006-09-06 | 2008-03-13 | Kyorin Pharmaceutical Co., Ltd. | Pyrazolopyridine derivative and phosphodiesterase (pde) inhibitor containing the same as active ingredient |
| US8263648B2 (en) * | 2006-09-11 | 2012-09-11 | Mylan Laboratories Ltd. | Diebenzofuran derivatives as inhibitors of PDE-4 and PDE-10 |
| WO2008057254A2 (en) * | 2006-10-27 | 2008-05-15 | Wyeth | Tricyclic compounds as matrix metalloproteinase inhibitors |
| WO2008065522A2 (en) * | 2006-11-29 | 2008-06-05 | Glenmark Pharmaceuticals S.A. | Process for the synthesis of 4-difluoromethoxy-8-nitro-1-formyl dibenzo[b,d] furan-an intermediate for pde iv inhibitors |
| US20100098641A1 (en) * | 2006-12-13 | 2010-04-22 | William Baker | Monophosphates as Mutual Prodrugs of Anti-Inflammatory Signal Transduction Modulators (AISTM's) and Beta-Agonists for the Treatment of Pulmonary Inflammation and Bronchoconstriction |
| MX2009008463A (es) * | 2007-02-09 | 2010-01-27 | Forest Lab Holdings Ltd | Formulaciones biodisponibles de compuestos heterociclicos. |
| US8524905B2 (en) | 2007-05-22 | 2013-09-03 | Glenmark Pharmaceuticals S.A. | Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors |
| US20110171195A1 (en) * | 2007-06-15 | 2011-07-14 | Duke University | Methods and compositions for treating urinary tract infections using agents that mimic or elevate cyclic amp |
| EP2070913A1 (en) | 2007-12-14 | 2009-06-17 | CHIESI FARMACEUTICI S.p.A. | Ester derivatives as phosphodiesterase inhibitors |
| WO2009147476A1 (en) * | 2008-06-02 | 2009-12-10 | Matrix Laboratories Ltd. | Novel pde inhibitors, pharmaceutical compositions containing them and processes for their preparation |
| TWI474282B (zh) * | 2008-10-03 | 2015-02-21 | Himax Tech Ltd | 深度相關的影像加強 |
| BRPI0922565A2 (pt) | 2008-12-19 | 2015-12-15 | Bristol Myers Squibb Co | compostos de carbazol carboxamida úteis como inibidores de cinase |
| WO2011132051A2 (en) * | 2010-04-19 | 2011-10-27 | Glenmark Pharmaceuticals S.A. | Tricycle compounds as phosphodiesterase-10 inhibitors |
| LT2651965T (lt) * | 2010-12-15 | 2019-01-10 | Contravir Pharmaceuticals, Inc. | Ciklosporino analogo molekulės su modifikuotomis 1 ir 3 aminorūgštimis |
| JP6225161B2 (ja) * | 2013-02-28 | 2017-11-01 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 呼吸器疾患の予防治療剤 |
| CN104177612A (zh) * | 2013-05-28 | 2014-12-03 | 韩文毅 | 一种新的非线性聚合物及其制备和用途 |
| CN104211947A (zh) * | 2013-05-31 | 2014-12-17 | 韩文毅 | 一种非线性聚合物及其制备和用途 |
| CN104211950A (zh) * | 2013-06-04 | 2014-12-17 | 韩文毅 | 一种非线性聚合物及其制备与用途 |
| CN104211949A (zh) * | 2013-06-04 | 2014-12-17 | 韩文毅 | 一种非线性聚合物及其制备与用途 |
| US20170107216A1 (en) | 2015-10-19 | 2017-04-20 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| AU2016358100B2 (en) | 2015-11-19 | 2021-05-27 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| TW201726623A (zh) | 2015-12-17 | 2017-08-01 | 英塞特公司 | 作為免疫調節劑之雜環化合物 |
| TWI850624B (zh) | 2015-12-22 | 2024-08-01 | 美商英塞特公司 | 作為免疫調節劑之雜環化合物 |
| RU2616617C1 (ru) * | 2016-04-12 | 2017-04-18 | Федеральное государственное бюджетное учреждение науки Институт органического синтеза им. И.Я. Постовского Уральского отделения Российской академии наук | 5-(9-этил-9Н-карбазол-3-ил)-4-[5-(9-этил-9Н-карбазол-3-ил)-тиофен-2-ил]-пиримидин |
| TW201808950A (zh) | 2016-05-06 | 2018-03-16 | 英塞特公司 | 作為免疫調節劑之雜環化合物 |
| US20170342060A1 (en) | 2016-05-26 | 2017-11-30 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| DK3472167T3 (da) | 2016-06-20 | 2022-09-05 | Incyte Corp | Heterocykliske forbindelser som immunomodulatorer |
| EP3484866B1 (en) | 2016-07-14 | 2022-09-07 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| EP3504198B1 (en) | 2016-08-29 | 2023-01-25 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| ES2874756T3 (es) | 2016-12-22 | 2021-11-05 | Incyte Corp | Derivados de triazolo[1,5-A]piridina como inmunomoduladores |
| EP3558963B1 (en) | 2016-12-22 | 2022-03-23 | Incyte Corporation | Bicyclic heteroaromatic compounds as immunomodulators |
| IL295660A (en) | 2016-12-22 | 2022-10-01 | Incyte Corp | Benzooxazole derivatives as immunomodulators |
| EP3558973B1 (en) | 2016-12-22 | 2021-09-15 | Incyte Corporation | Pyridine derivatives as immunomodulators |
| RS64055B1 (sr) | 2018-03-30 | 2023-04-28 | Incyte Corp | Heterociklična jedinjenja kao imunomodulatori |
| EP4219492B1 (en) | 2018-05-11 | 2024-11-27 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| CN109651232A (zh) * | 2018-12-12 | 2019-04-19 | 河北华清光电材料有限公司 | 制备4-溴咔唑及其衍生物的方法 |
| JP7665593B2 (ja) | 2019-08-09 | 2025-04-21 | インサイト・コーポレイション | Pd-1/pd-l1阻害剤の塩 |
| EP4037773A1 (en) | 2019-09-30 | 2022-08-10 | Incyte Corporation | Pyrido[3,2-d]pyrimidine compounds as immunomodulators |
| BR112022009031A2 (pt) | 2019-11-11 | 2022-10-11 | Incyte Corp | Sais e formas cristalinas de um inibidor de pd-1/pd-l1 |
| US11760756B2 (en) | 2020-11-06 | 2023-09-19 | Incyte Corporation | Crystalline form of a PD-1/PD-L1 inhibitor |
| EP4240739A1 (en) | 2020-11-06 | 2023-09-13 | Incyte Corporation | Process for making a pd-1/pd-l1 inhibitor and salts and crystalline forms thereof |
| WO2022099018A1 (en) | 2020-11-06 | 2022-05-12 | Incyte Corporation | Process of preparing a pd-1/pd-l1 inhibitor |
| CN114163417B (zh) * | 2021-12-06 | 2023-08-04 | 郑州海阔光电材料有限公司 | 一种3-溴硫芴的合成方法 |
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|---|---|---|---|---|
| GB1041861A (en) | 1962-03-14 | 1966-09-07 | Organon Labor Ltd | Pyrrolidone derivatives and pharmaceutical preparations containing them |
| US3759948A (en) * | 1969-06-25 | 1973-09-18 | Merck & Co Inc | Non-steroid anti-inflammatory compounds |
| NL7008628A (is) * | 1969-06-25 | 1970-12-29 | ||
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-
2004
- 2004-02-11 PL PL378813A patent/PL378813A1/pl not_active Application Discontinuation
- 2004-02-11 DK DK04710093T patent/DK1620429T3/da active
- 2004-02-11 AU AU2004228453A patent/AU2004228453B2/en not_active Expired - Fee Related
- 2004-02-11 CA CA002522023A patent/CA2522023A1/en not_active Abandoned
- 2004-02-11 SI SI200431133T patent/SI1620429T1/sl unknown
- 2004-02-11 PT PT04710093T patent/PT1620429E/pt unknown
- 2004-02-11 AT AT04710093T patent/ATE427308T1/de not_active IP Right Cessation
- 2004-02-11 JP JP2006506259A patent/JP2006522789A/ja active Pending
- 2004-02-11 EP EP04710093A patent/EP1620429B1/en not_active Expired - Lifetime
- 2004-02-11 MX MXPA05010948A patent/MXPA05010948A/es active IP Right Grant
- 2004-02-11 ES ES04710093T patent/ES2320888T3/es not_active Expired - Lifetime
- 2004-02-11 DE DE602004020332T patent/DE602004020332D1/de not_active Expired - Lifetime
- 2004-02-11 CN CN2004800160486A patent/CN1829711B/zh not_active Expired - Fee Related
- 2004-02-11 NZ NZ542882A patent/NZ542882A/en unknown
- 2004-02-11 OA OA1200500280A patent/OA13154A/en unknown
- 2004-02-11 AP AP2005003424A patent/AP2008A/xx active
- 2004-02-11 HR HR20050944A patent/HRP20050944A2/xx not_active Application Discontinuation
- 2004-02-11 KR KR1020057019359A patent/KR20060017494A/ko not_active Ceased
- 2004-02-11 WO PCT/IB2004/000355 patent/WO2004089940A1/en not_active Ceased
- 2004-02-11 BR BRPI0409747-5A patent/BRPI0409747A/pt not_active IP Right Cessation
- 2004-02-11 EA EA200501617A patent/EA010634B1/ru not_active IP Right Cessation
- 2004-02-11 GE GEAP20049048A patent/GEP20084526B/en unknown
- 2004-02-17 AR ARP040100483A patent/AR043199A1/es unknown
- 2004-02-24 TW TW093104603A patent/TW200508212A/zh unknown
- 2004-03-09 MY MYPI20040813A patent/MY136516A/en unknown
- 2004-03-15 CL CL200400526A patent/CL2004000526A1/es unknown
- 2004-04-09 US US10/821,642 patent/US7223789B2/en not_active Expired - Lifetime
- 2004-11-02 UA UAA200510680A patent/UA79558C2/uk unknown
-
2005
- 2005-10-06 TN TNP2005000252A patent/TNSN05252A1/en unknown
- 2005-10-12 ZA ZA200508240A patent/ZA200508240B/en unknown
- 2005-11-09 MA MA28593A patent/MA27801A1/fr unknown
- 2005-11-10 NO NO20055316A patent/NO20055316L/no not_active Application Discontinuation
- 2005-11-10 IS IS8123A patent/IS8123A/is unknown
- 2005-11-11 CO CO05115151A patent/CO5700824A2/es not_active Application Discontinuation
-
2006
- 2006-09-28 US US11/536,448 patent/US7393846B2/en not_active Expired - Fee Related
- 2006-09-28 US US11/536,434 patent/US7384962B2/en not_active Expired - Fee Related
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2008
- 2008-06-02 US US12/131,286 patent/US20090182143A1/en not_active Abandoned
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