PE35896A1 - Heteroaril-oxazolidinona de 5 eslabones - Google Patents

Heteroaril-oxazolidinona de 5 eslabones

Info

Publication number
PE35896A1
PE35896A1 PE1995274242A PE27424295A PE35896A1 PE 35896 A1 PE35896 A1 PE 35896A1 PE 1995274242 A PE1995274242 A PE 1995274242A PE 27424295 A PE27424295 A PE 27424295A PE 35896 A1 PE35896 A1 PE 35896A1
Authority
PE
Peru
Prior art keywords
carbon
preference
formula
group
atoms
Prior art date
Application number
PE1995274242A
Other languages
English (en)
Inventor
Dieter Habich
Andreas Stolle
Hanno Wild
Hein-Peter Kroll
Klaus Dieter Bremm
Klaus Schaller
Hans-Otto Werling
Rainer Endermann
Bernd Riedl
Harald Labischinski
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PE35896A1 publication Critical patent/PE35896A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

SE REFIERE AL COMPUESTO DE FORMULA I DONDE: R1 REPRESENTA AZIDO, HIDROXILO o UN GRUPO DE FORMULA -OR2, -OSO2R3 o -NR4R5, DONDE R2 ES ACILO, LINEAL o RAMIFICADO, CON HASTA OCHO ATOMOS DE CARBONO, DE PREFERENCIA SEIS; R3 ES ALQUILO LINEAL O RAMIFICADO, CON HASTA CUATRO ATOMOS DE CARBONO, DE PREFERENCIA TRES, PUDIENDO SER METILO, ETILO, FENILO O TOLILO; R4 Y R5 SON IGUALES O DISTINTOS Y SIGNIFICAN CICLOALQUILO CON TRES A SEIS ATOMOS DE CARBONO, DE PREFERENCIA CICLOPROPILO O CICLOPENTILO, o R4 Y R5 SIGNIFICA UN GRUPO DE FORMULA -CO-R6 DONDE R6 ES CICLOALQUILO CON TRES A SEIS ATOMOS DE CARBONO, DE PREFERENCIA CICLOPROPILO, CICLOBUTILO, ENTRE OTROS; A REPRESENTA UN HETEROCICLO AROMATICO DE CINCO ESLABONES UNIDO DIRECTAMENTE SOBRE UN ATOMO DE CARBONO, CON HASTA TRES HETEROATOMOS DEL GRUPO S, N y/u O, QUE ADICIONALMENTE PUEDE POSEER UN ANILLO DE BENCENO O NAFTALENO CONDENSADO, DONDE LOS CICLOS PUEDEN ESTAR HASTA TRISUSTITUIDO POR SUSTITUYENTES IGUALES O DISTINTINTOS TALES COMO CARBOXI, HALOGENO, CIANO, MERCAPTO, FORMILO, ENTRE OTROS, PUDIENDO DE PREFERENCIA SER PIRROLILO, IMIDAZOLILO, FURILO, ENTRE OTROS. ESTOS MEDICAMENTOS SE CARACTERIZAN POR SER ANTIBACTERIANOS
PE1995274242A 1994-07-20 1995-07-19 Heteroaril-oxazolidinona de 5 eslabones PE35896A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425613A DE4425613A1 (de) 1994-07-20 1994-07-20 5-gliedrige Heteroaryl-oxazolidinone

Publications (1)

Publication Number Publication Date
PE35896A1 true PE35896A1 (es) 1996-10-14

Family

ID=6523633

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1995274242A PE35896A1 (es) 1994-07-20 1995-07-19 Heteroaril-oxazolidinona de 5 eslabones

Country Status (28)

Country Link
US (1) US5698574A (es)
EP (1) EP0693491A1 (es)
JP (1) JPH0853443A (es)
KR (1) KR960004343A (es)
CN (1) CN1121919A (es)
AU (1) AU695661B2 (es)
BG (1) BG99791A (es)
CA (1) CA2154026A1 (es)
CO (1) CO4410193A1 (es)
CZ (1) CZ187395A3 (es)
DE (1) DE4425613A1 (es)
EE (1) EE9500044A (es)
FI (1) FI953476A7 (es)
HR (1) HRP950391A2 (es)
HU (1) HUT74003A (es)
IL (1) IL114622A (es)
MA (1) MA23621A1 (es)
NO (1) NO304488B1 (es)
NZ (1) NZ272596A (es)
PE (1) PE35896A1 (es)
PL (1) PL309685A1 (es)
RO (1) RO115161B1 (es)
RU (1) RU95113086A (es)
SK (1) SK91695A3 (es)
SV (1) SV1995000042A (es)
TN (1) TNSN95083A1 (es)
YU (1) YU49195A (es)
ZA (1) ZA956015B (es)

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US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
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Also Published As

Publication number Publication date
SV1995000042A (es) 1996-03-28
NZ272596A (en) 1997-03-24
FI953476A0 (fi) 1995-07-18
CO4410193A1 (es) 1997-01-09
KR960004343A (ko) 1996-02-23
CA2154026A1 (en) 1996-01-21
RU95113086A (ru) 1997-06-27
TNSN95083A1 (fr) 1996-02-06
CN1121919A (zh) 1996-05-08
ZA956015B (en) 1996-02-22
HU9502167D0 (en) 1995-09-28
NO952866L (no) 1996-01-22
IL114622A (en) 1999-07-14
RO115161B1 (ro) 1999-11-30
HRP950391A2 (en) 1997-06-30
AU695661B2 (en) 1998-08-20
CZ187395A3 (en) 1996-02-14
IL114622A0 (en) 1995-11-27
AU2498895A (en) 1996-02-01
NO952866D0 (no) 1995-07-19
NO304488B1 (no) 1998-12-28
HUT74003A (en) 1996-10-28
MA23621A1 (fr) 1996-04-01
US5698574A (en) 1997-12-16
PL309685A1 (en) 1996-01-22
FI953476L (fi) 1996-01-21
FI953476A7 (fi) 1996-01-21
EE9500044A (et) 1996-02-15
YU49195A (sh) 1998-12-23
BG99791A (en) 1996-04-30
SK91695A3 (en) 1996-02-07
JPH0853443A (ja) 1996-02-27
EP0693491A1 (de) 1996-01-24
DE4425613A1 (de) 1996-01-25

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