PH24026A - Method of treating multiple sclerosis with chalcone derivatives - Google Patents

Method of treating multiple sclerosis with chalcone derivatives

Info

Publication number: PH24026A
Authority: PH; Philippines
Prior art keywords: multiple sclerosis; chalcone derivatives; treating multiple; inhibit; derivatives
Prior art date: 1987-04-09

Application number

PH36740A

Other languages

English (en)

Inventor

David M Stemerick

Michael L Edwards

Sai Prasad Sunkara

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-09

Filing date

1988-04-05

Publication date

1990-02-09

1988-04-05 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1990-02-09 Publication of PH24026A publication Critical patent/PH24026A/en

Links

201000006417 multiple sclerosis Diseases 0.000 title abstract 3
150000001788 chalcone derivatives Chemical class 0.000 title abstract 2
102000029749 Microtubule Human genes 0.000 abstract 1
108091022875 Microtubule Proteins 0.000 abstract 1
102000004243 Tubulin Human genes 0.000 abstract 1
108090000704 Tubulin Proteins 0.000 abstract 1
210000003050 axon Anatomy 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
230000006378 damage Effects 0.000 abstract 1
210000004688 microtubule Anatomy 0.000 abstract 1
210000003007 myelin sheath Anatomy 0.000 abstract 1
238000006116 polymerization reaction Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

PH36740A 1987-04-09 1988-04-05 Method of treating multiple sclerosis with chalcone derivatives PH24026A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/036,237 US4753965A (en)	1987-04-09	1987-04-09	Method of treating multiple sclerosis with chalcone derivatives

Publications (1)

Publication Number	Publication Date
PH24026A true PH24026A (en)	1990-02-09

Family

ID=21887460

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH36740A PH24026A (en)	1987-04-09	1988-04-05	Method of treating multiple sclerosis with chalcone derivatives

Country Status (10)

Country	Link
US (1)	US4753965A (fr)
EP (1)	EP0286083B1 (fr)
KR (1)	KR880012218A (fr)
AT (1)	ATE92465T1 (fr)
AU (1)	AU599221B2 (fr)
DE (1)	DE3882771T2 (fr)
ES (1)	ES2059420T3 (fr)
IE (1)	IE63158B1 (fr)
PH (1)	PH24026A (fr)
ZA (1)	ZA882392B (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62207212A (ja) *	1986-03-08	1987-09-11	Nippon Haipotsukusu:Kk	抗アレルギ−剤
US4863968A (en) *	1987-04-09	1989-09-05	Merrell Dow Pharmaceuticals Inc.	Methods of treating gout with chalcone derivatives
US4904697A (en) *	1987-04-09	1990-02-27	Merrell Dow Pharmaceuticals Inc.	Controlling the growth of certain tumor tissue with chalcone derivatives
CA2051501C (fr) *	1990-09-20	2004-02-17	Robert J. Dinerstein	1-phenyl-3-phenyl-2-propyne-1-ones comme inhibiteurs de l'assimilation du calcium
US5681812A (en) *	1991-12-10	1997-10-28	Rush Presbyterian-St. Luke's Medical Center	Methods and compositions for reducing multidrug resistance
CA2125279A1 (fr) *	1991-12-10	1993-06-24	John Sayler Coon	Methodes et compositions pour reduire la resistance polymedicamenteuse
US5952355A (en) *	1993-11-17	1999-09-14	Kyowa Hakko Kogyo Co., Ltd.	Propenone derivatives
US6495579B1 (en)	1996-12-02	2002-12-17	Angiotech Pharmaceuticals, Inc.	Method for treating multiple sclerosis
US20030157187A1 (en) *	1996-12-02	2003-08-21	Angiotech Pharmaceuticals, Inc.	Compositions and methods for treating or preventing inflammatory diseases
US6515016B2 (en)	1996-12-02	2003-02-04	Angiotech Pharmaceuticals, Inc.	Composition and methods of paclitaxel for treating psoriasis
US8680059B2 (en) *	1998-05-20	2014-03-25	Biotempt B.V.	Oligopeptide acetate and formulations thereof
US6844315B2 (en)	1998-05-20	2005-01-18	Erasmus Universiteit Rotterdam	Immunoregulator
US20030220258A1 (en)	2001-12-21	2003-11-27	Robbert Benner	Treatment of ischemic events
US20050227925A1 (en) *	2004-04-08	2005-10-13	Robbert Benner	Compositions capable of reducing elevated blood urea concentration
US20040202645A1 (en) *	2003-04-08	2004-10-14	Khan Nisar Ahmed	Administration of gene-regulatory peptides
US6921751B1 (en) *	1998-05-20	2005-07-26	Erasmus Universiteit Rotterdam	Immunoregulator
EP1300418A1 (fr) *	2001-10-04	2003-04-09	Erasmus Universiteit Rotterdam	Régulation génétique par des oligopeptides
US7358330B2 (en)	2001-03-29	2008-04-15	Biotempt B.V.	Immunoregulatory compositions
US20030220257A1 (en) *	2001-12-21	2003-11-27	Robbert Benner	Treatment of trauma
US20030224995A1 (en) *	2001-12-21	2003-12-04	Khan Nisar Ahmed	Treatment of burns
US7786084B2 (en) *	2001-12-21	2010-08-31	Biotempt B.V.	Treatment of burns
US20030220261A1 (en) *	2001-12-21	2003-11-27	Khan Nisar Ahmed	Treatment of iatrogenic disease
US20030220260A1 (en) *	2001-12-21	2003-11-27	Khan Nisar Ahmed	Peptide compositions
US20080242837A1 (en) *	2001-12-21	2008-10-02	Khan Nisar A	Peptide compositions
US20080318871A1 (en) *	2001-12-21	2008-12-25	Khan Nisar A	Treatment of neurological disorders
US7560433B2 (en) *	2001-12-21	2009-07-14	Biotempt B.V.	Treatment of multiple sclerosis (MS)
US20040013661A1 (en) *	2001-12-21	2004-01-22	Gert Wensvoort	Stratification
US7501391B2 (en) *	2001-12-21	2009-03-10	Biotempt B.V.	Treatment of transplant survival
AUPS110302A0 (en) *	2002-03-14	2002-04-18	Biomolecular Research Institute Limited	Novel chalcone derivatives and uses thereof
AUPS127202A0 (en) *	2002-03-20	2002-04-18	Walter And Eliza Hall Institute Of Medical Research, The	Therapeutic ion channel blocking agents and methods of use thereof
US7326734B2 (en) *	2003-04-01	2008-02-05	The Regents Of The University Of California	Treatment of bladder and urinary tract cancers
US20090227505A1 (en) *	2004-01-07	2009-09-10	Biotempt B.V.	Methods and uses for protein breakdown products
JP4846799B2 (ja) *	2005-07-05	2011-12-28	バイオテンプトベー．フェー．	腫瘍の治療
US20070202077A1 (en) *	2005-12-02	2007-08-30	Brodsky Robert A	Use of High-Dose Oxazaphosphorine Drugs for Treating Immune Disorders
EP1864692A1 (fr) *	2006-06-07	2007-12-12	Biotempt B.V.	Utilisation de peptides pour la protection contre les radiolésions
WO2008034074A2 (fr)	2006-09-15	2008-03-20	The Johns Hopkins University	Utilisation de cyclophosphamide à doses élevées en combinaison avec des vaccins anti-idiotypiques dans le traitement anticancéreux
WO2008034071A2 (fr)	2006-09-15	2008-03-20	The Johns Hopkins University	Procédé d'identification de patients approprié pour un traitement à la cyclophosphamide par de fortes doses
WO2008034076A2 (fr)	2006-09-15	2008-03-20	The Johns Hopkins University	Utilisation de cyclophosphamide à doses élevées en combinaison avec des thérapeutiques d'immunisation dans le traitement anticancer
DK2120991T3 (da) *	2007-02-12	2014-04-28	Biotempt Bv	Behandling af traumatisk blødning med korte oligopeptider
WO2009067699A2 (fr) *	2007-11-21	2009-05-28	Accentia Biopharmaceuticals, Inc.	Procédés pour dispenser un système de soin pour un régime à base de médicament de type oxazaphosphorine
US9026372B2 (en) *	2007-11-21	2015-05-05	Accentia Biopharmaceuticals, Inc.	Methods for providing a system of care for a high-dose oxazaphosphorine drug regimen

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL131029C (fr) *	1959-08-20
GB1283981A (en) *	1969-03-05	1972-08-02	Orsymonde	2,4,6-trihydroxy chalcone derivatives
US3808006A (en) *	1971-12-06	1974-04-30	Minnesota Mining & Mfg	Photosensitive material containing a diaryliodium compound, a sensitizer and a color former
US3729313A (en) *	1971-12-06	1973-04-24	Minnesota Mining & Mfg	Novel photosensitive systems comprising diaryliodonium compounds and their use
DE2558813C2 (de) *	1975-12-27	1984-10-31	Hoechst Ag, 6230 Frankfurt	Lichtempfindliches Gemisch mit synergistischem Initiatorsystem
DE2602419A1 (de) *	1976-01-23	1977-07-28	Basf Ag	Photopolymerisierbare masse
JPS6026122B2 (ja) *	1977-01-20	1985-06-21	富士写真フイルム株式会社	光重合性組成物
US4162162A (en) *	1978-05-08	1979-07-24	E. I. Du Pont De Nemours And Company	Derivatives of aryl ketones and p-dialkyl-aminoarylaldehydes as visible sensitizers of photopolymerizable compositions
JPS54152091A (en) *	1978-05-22	1979-11-29	Fuji Photo Film Co Ltd	Photopolymerizable composition
US4279930A (en) *	1978-10-10	1981-07-21	The Upjohn Company	Process for treating inflammation
NZ192641A (en) *	1979-01-26	1984-10-19	Hoffmann La Roche	Substituted acetophenones and pharmaceutical compositions
EP0028305B1 (fr) *	1979-09-13	1984-02-01	The Wellcome Foundation Limited	Composés diaryle et compositions pharmaceutiques les contenant
CA1168659A (fr) *	1980-08-06	1984-06-05	Gerard Lang	Derives de dibenzoylmethane quaternaire, leur utilisation comme agent filtrant solaire et composition cosmetique les contenant
US4904697A (en) *	1987-04-09	1990-02-27	Merrell Dow Pharmaceuticals Inc.	Controlling the growth of certain tumor tissue with chalcone derivatives

1987
- 1987-04-09 US US07/036,237 patent/US4753965A/en not_active Expired - Fee Related
1988
- 1988-04-05 ZA ZA882392A patent/ZA882392B/xx unknown
- 1988-04-05 PH PH36740A patent/PH24026A/en unknown
- 1988-04-05 AU AU14166/88A patent/AU599221B2/en not_active Ceased
- 1988-04-07 ES ES88105539T patent/ES2059420T3/es not_active Expired - Lifetime
- 1988-04-07 EP EP88105539A patent/EP0286083B1/fr not_active Expired - Lifetime
- 1988-04-07 AT AT88105539T patent/ATE92465T1/de not_active IP Right Cessation
- 1988-04-07 DE DE88105539T patent/DE3882771T2/de not_active Expired - Fee Related
- 1988-04-08 IE IE107888A patent/IE63158B1/en not_active IP Right Cessation
- 1988-04-08 KR KR1019880003947A patent/KR880012218A/ko not_active Withdrawn

Also Published As

Publication number	Publication date
DE3882771D1 (de)	1993-09-09
ATE92465T1 (de)	1993-08-15
IE881078L (en)	1988-10-09
AU1416688A (en)	1988-10-13
AU599221B2 (en)	1990-07-12
IE63158B1 (en)	1995-03-22
ES2059420T3 (es)	1994-11-16
EP0286083A3 (en)	1990-02-14
EP0286083A2 (fr)	1988-10-12
KR880012218A (ko)	1988-11-26
EP0286083B1 (fr)	1993-08-04
DE3882771T2 (de)	1994-02-24
US4753965A (en)	1988-06-28
ZA882392B (en)	1988-11-30

Publication	Publication Date	Title
PH24026A (en)	1990-02-09	Method of treating multiple sclerosis with chalcone derivatives
AU6760987A (en)	1987-07-16	Method of treating alzheimer's disease
AU1897088A (en)	1990-01-18	Method of treating patients suffering from chronic pain or chronic cough
ATE213411T1 (de)	2002-03-15	Verwendung von phenserin zur herstellung von medikamenten zur behandlung von kognitiven störungen
DE58902094D1 (de)	1992-10-01	Kombinationspraeparat zur behandlung von nervenzell-und nervenfasererkrankungen und verletzungen.
PH25183A (en)	1991-03-27	Controlling the growth of certain tumor tissue with chalcone derivatives
GB8708115D0 (en)	1987-05-13	Coagulation treatment of fluids
EP0502925A4 (en)	1992-12-16	Method and composition for treating inflammatory bowel disorders
DE3878627D1 (de)	1993-04-01	Zusammensetzung zur oberflaechenbehandlung von kautschuk.
EP0360006A3 (en)	1990-04-04	Acid-resistant fibroblast growth factor composition and method of treating ulcerating diseases of the gastrointestinal tract
AU2883689A (en)	1989-08-03	The use of moclobemide to treat or prevent cognitive disorders
AU3133889A (en)	1989-09-21	Method for the treatment of the extraphyramidal side effects associated with neuroleptic therapy
IE871567L (en)	1987-12-16	Method for treating depression
HUT47427A (en)	1989-03-28	Bezafibrat for treating diabetes
NZ247406A (en)	1999-05-28	Treatment of osteoporosis with 1 alpha, 24(r)-dihydroxy-22(e)-dehydro-vitamin d3
HUT59307A (en)	1992-05-28	Process for producing pharmaceutical compositions comprising zofenopril and suitable for treating arthritis
ATE107166T1 (de)	1994-07-15	Verwendung von chlormethiazol zur herstellung eines artzneimittels zur prophylaxe oder therapie der neurodegeneration.
AU1416588A (en)	1988-10-13	Methods of treating gout with chalcone derivatives
AU1923688A (en)	1989-01-27	Method of treating repetitive strain injury
UA22037A (uk)	1998-04-30	Спосіб лікуваhhя виразкової хвороби шлуhка та дваhадцятипалої кишки
IE882117L (en)	1990-01-11	Treating patients suffering from chronic pain or cough
UA22039A (uk)	1998-04-30	Спосіб лікуваhhя хроhічhого субкомпеhсоваhого тоhзиліту
GB8817446D0 (en)	1988-08-24	Treatment of various blood disorders
GB8800565D0 (en)	1988-02-10	Method of treatment
GB8801688D0 (en)	1988-02-24	Method of treatment