PH24217A - 7-fluoro-dihydro pgi compounds - Google Patents

7-fluoro-dihydro pgi compounds

Info

Publication number
PH24217A
PH24217A PH33921A PH33921A PH24217A PH 24217 A PH24217 A PH 24217A PH 33921 A PH33921 A PH 33921A PH 33921 A PH33921 A PH 33921A PH 24217 A PH24217 A PH 24217A
Authority
PH
Philippines
Prior art keywords
fluoro
dihydro
hydrogen
compounds
pgi
Prior art date
Application number
PH33921A
Other languages
English (en)
Inventor
George William Holland
Perry Rosen
Hans Maag
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PH24217A publication Critical patent/PH24217A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Furan Compounds (AREA)
PH33921A 1985-06-24 1986-06-20 7-fluoro-dihydro pgi compounds PH24217A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/747,740 US4634782A (en) 1985-06-24 1985-06-24 7-fluoro-dihydro PGI compounds

Publications (1)

Publication Number Publication Date
PH24217A true PH24217A (en) 1990-04-10

Family

ID=25006425

Family Applications (1)

Application Number Title Priority Date Filing Date
PH33921A PH24217A (en) 1985-06-24 1986-06-20 7-fluoro-dihydro pgi compounds

Country Status (11)

Country Link
US (1) US4634782A (de)
EP (1) EP0209694B1 (de)
JP (1) JPS62482A (de)
AT (1) ATE45575T1 (de)
AU (1) AU595533B2 (de)
DE (1) DE3665063D1 (de)
DK (1) DK295586A (de)
IL (1) IL79168A0 (de)
NZ (1) NZ216613A (de)
PH (1) PH24217A (de)
ZA (1) ZA864590B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd ７−フルオロプロスタグランジン類の製造方法
CH674363A5 (de) * 1986-12-01 1990-05-31 Hoffmann La Roche
US4808734A (en) * 1986-12-01 1989-02-28 Hoffmann-La Roche Inc. 16-cycloalkyl-7-fluoro-prostacyclins
DE69531110T2 (de) * 1994-02-17 2004-05-19 Asahi Glass Co., Ltd. Difluoroprostacycline, Zwischenprodukte zu deren Herstellung und Herstellungsverfahren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6570680A (en) * 1979-10-10 1981-04-28 University Of Chicago, The Chemical synthesis
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
EP0054795B1 (de) * 1980-12-09 1987-07-15 Teijin Limited Halogenierte Prostacycline, Verfahren zu ihrer Herstellung und ihre Anwendung in der Pharmazie
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH651033A5 (de) * 1981-03-11 1985-08-30 Hoffmann La Roche Fluorprostacycline.
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd ７−フルオロプロスタグランジン類の製造方法

Also Published As

Publication number Publication date
DK295586A (da) 1986-12-25
AU5920486A (en) 1987-01-08
EP0209694B1 (de) 1989-08-16
IL79168A0 (en) 1986-09-30
AU595533B2 (en) 1990-04-05
ZA864590B (en) 1987-02-25
JPS62482A (ja) 1987-01-06
US4634782A (en) 1987-01-06
DK295586D0 (da) 1986-06-23
EP0209694A1 (de) 1987-01-28
ATE45575T1 (de) 1989-09-15
NZ216613A (en) 1989-04-26
DE3665063D1 (en) 1989-09-21

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