PH24377A - Formulations suitable for the stabilisation of alpha-interferon - Google Patents

Formulations suitable for the stabilisation of alpha-interferon

Info

Publication number: PH24377A
Authority: PH; Philippines
Prior art keywords: active ingredient; alpha; stabilisation; interferon; formulations suitable
Prior art date: 1986-02-05

Application number

PH34815A

Other languages

English (en)

Inventor

Helmut Dr Franz

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-02-05

Filing date

1987-02-05

Publication date

1990-06-13

1987-02-05 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1990-06-13 Publication of PH24377A publication Critical patent/PH24377A/en

Links

239000000203 mixture Substances 0.000 title abstract 2
238000009472 formulation Methods 0.000 title 1
230000006641 stabilisation Effects 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 3
238000012270 DNA recombination Methods 0.000 abstract 1
108010010803 Gelatin Proteins 0.000 abstract 1
229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 1
239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 1
229920000159 gelatin Polymers 0.000 abstract 1
239000008273 gelatin Substances 0.000 abstract 1
235000019322 gelatine Nutrition 0.000 abstract 1
235000011852 gelatine desserts Nutrition 0.000 abstract 1
235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1
238000011200 topical administration Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Inorganic Chemistry (AREA)
Immunology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

PH34815A 1986-02-05 1987-02-05 Formulations suitable for the stabilisation of alpha-interferon PH24377A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19863603444 DE3603444A1 (de)	1986-02-05	1986-02-05	Pharmazeutische zubereitungsformen zur stabilisierung von interferon alpha

Publications (1)

Publication Number	Publication Date
PH24377A true PH24377A (en)	1990-06-13

Family

ID=6293372

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH34815A PH24377A (en)	1986-02-05	1987-02-05	Formulations suitable for the stabilisation of alpha-interferon

Country Status (20)

Country	Link
EP (1)	EP0231816B1 (da)
JP (1)	JPS62209024A (da)
KR (1)	KR870007698A (da)
AT (1)	ATE63823T1 (da)
AU (1)	AU601712B2 (da)
CA (1)	CA1295242C (da)
DD (1)	DD284602A5 (da)
DE (2)	DE3603444A1 (da)
DK (1)	DK164202C (da)
ES (1)	ES2028796T3 (da)
FI (1)	FI86144C (da)
GR (1)	GR3002270T3 (da)
HU (1)	HU196560B (da)
IE (1)	IE59697B1 (da)
IL (1)	IL81472A0 (da)
NO (1)	NO169638C (da)
NZ (1)	NZ219169A (da)
PH (1)	PH24377A (da)
PT (1)	PT84243B (da)
ZA (1)	ZA87793B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5275804A (en) *	1986-02-25	1994-01-04	E. B. Michaels Research Associates, Inc.	Process and composition for oral hygiene
DE3731255A1 (de) *	1987-09-17	1989-04-06	Boehringer Ingelheim Int	Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen
US5266310A (en) *	1987-09-17	1993-11-30	Boehringer Ingelheim International Gmbh	Stabilization of therapeutically active proteins in pharmaceutical preparations
DE3803312A1 (de) *	1988-02-04	1989-08-10	Gerd Prof Dr Med Gross	Verwendung eines interferonenthaltenden gels
NZ228285A (en) *	1988-03-11	1991-08-27	Teikoku Seiyaku Kk	Pharmaceutical composition comprising a polypeptide and adapted for intravaginal administration
WO1989010756A1 (fr) *	1988-05-06	1989-11-16	Toray Industries, Inc.	COMPOSITION D'INTERFERON beta STABLE
US5389676A (en) *	1991-03-22	1995-02-14	E. B. Michaels Research Associates, Inc.	Viscous surfactant emulsion compositions
US5244652A (en) *	1991-03-22	1993-09-14	E. B. Michaels Research Associates, Inc.	Viscous surface active composition
US5863530A (en) *	1991-10-11	1999-01-26	Spruson & Ferguson	Treating ophthalmic fibrosis using interferon-α
WO1993006856A1 (en) *	1991-10-11	1993-04-15	Mark Cedric Gillies	Treating ophthalmic fibrosis using interferon-alpha
US6630168B1 (en)	1997-02-20	2003-10-07	Biomedicines, Inc.	Gel delivery vehicles for anticellular proliferative agents
FI106465B (fi) *	1998-06-10	2001-02-15	Suomen Punainen Risti Veripalv	Menetelmä virusturvallisten farmaseuttisten koostumusten valmistamiseksi
US6923966B2 (en)	1999-04-08	2005-08-02	Schering Corporation	Melanoma therapy
JP4536194B2 (ja) *	2000-02-17	2010-09-01	大日本住友製薬株式会社	安定な注射用製剤
ES2357474T3 (es) *	2000-03-07	2011-04-26	Rush-Presbyterian-St.Luke's Medical Center	Composiciones y su uso para atrapar e inactivar microbios patógenos y espermatoziodes.
US6328987B1 (en) *	2000-11-03	2001-12-11	Jan Marini Skin Research, Inc.	Cosmetic skin care compositions containing alpha interferon
EP1449540A4 (en) *	2001-11-02	2007-01-10	Sekisui Chemical Co Ltd	CYTOKIN INDUCING MATERAIL AND CYTOKIN INDUCTIVE INSTRUMENT
US8137677B2 (en) *	2005-10-06	2012-03-20	Allergan, Inc.	Non-protein stabilized clostridial toxin pharmaceutical compositions
MY188369A (en) *	2009-05-29	2021-12-06	Filligent Ltd	Composition for use in decreasing the transmission of human pathogens
RU2431489C1 (ru) *	2010-05-25	2011-10-20	Федеральное государственное учреждение "Российский научный центр рентгенорадиологии Федерального агентства по высокотехнологичной медицинской помощи" (ФГУ "РНЦРР Росмедтехнологий")	Способ лечения хронических воспалительных заболеваний толстого кишечника
CN104271142B (zh) *	2012-03-01	2017-07-04	福斯特斯特林研究公司	含有α连接蛋白C‑末端(ACT)肽的局部凝胶
JP6081156B2 (ja) *	2012-11-15	2017-02-15	アルケア株式会社	ハイドロゲル
DE102012222365A1 (de)	2012-12-05	2014-06-05	Aesculap Ag	Zusammensetzung zur Anwendung bei der Prophylaxe von post-chirurgischen Adhäsionen
CA2913115A1 (en) *	2013-06-09	2014-12-18	Efranat Ltd.	Compositions comprising gc-macrophage activating factor and uses thereof
WO2018143911A1 (en)	2017-01-31	2018-08-09	Kimberly-Clark Worldwide, Inc.	Antibacterial composition including benzoic acid ester and methods of inhibiting bacterial growth utilizing the same
MX2023004631A (es)	2020-10-22	2023-07-20	Xequel Bio Inc	Formulaciones peptidicas y usos oftalmicos de las mismas.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1234383A (en) *	1982-03-17	1983-09-22	Inter-Yeda Ltd.	Interferon stabilised with polyvinyl-pyrrolidone
JPS6061535A (ja) *	1983-08-24	1985-04-09	エフ・ホフマン・ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト	製薬学的組成物
JPS6069037A (ja) *	1983-09-26	1985-04-19	Sunstar Inc	エリテマト−デス治療用外用剤
EP0139286B1 (en) *	1983-10-14	1991-08-21	Sumitomo Pharmaceuticals Company, Limited	Prolonged sustained-release preparations
US4680175A (en) *	1984-02-07	1987-07-14	Interferon Sciences, Inc.	Interferon administration vehicles
CA1248450A (en) *	1984-04-05	1989-01-10	Kazuo Kigasawa	Soft patch
JPS60228422A (ja) *	1984-04-26	1985-11-13	Suntory Ltd	安定化された生理活性物質製剤
JPS60260523A (ja) *	1984-06-07	1985-12-23	Asahi Chem Ind Co Ltd	インタ−フエロンの凍結乾燥医薬組成物

1986
- 1986-02-05 DE DE19863603444 patent/DE3603444A1/de not_active Withdrawn
1987
- 1987-01-21 EP EP87100792A patent/EP0231816B1/de not_active Expired - Lifetime
- 1987-01-21 DE DE8787100792T patent/DE3770280D1/de not_active Expired - Lifetime
- 1987-01-21 ES ES198787100792T patent/ES2028796T3/es not_active Expired - Lifetime
- 1987-01-21 AT AT87100792T patent/ATE63823T1/de not_active IP Right Cessation
- 1987-02-03 DD DD87299676A patent/DD284602A5/de not_active IP Right Cessation
- 1987-02-03 CA CA000528832A patent/CA1295242C/en not_active Expired - Lifetime
- 1987-02-03 FI FI870457A patent/FI86144C/fi not_active IP Right Cessation
- 1987-02-04 IL IL81472A patent/IL81472A0/xx not_active IP Right Cessation
- 1987-02-04 IE IE29587A patent/IE59697B1/en not_active IP Right Cessation
- 1987-02-04 NO NO870441A patent/NO169638C/no unknown
- 1987-02-04 HU HU87385A patent/HU196560B/hu not_active IP Right Cessation
- 1987-02-04 JP JP62024423A patent/JPS62209024A/ja active Pending
- 1987-02-04 PT PT84243A patent/PT84243B/pt not_active IP Right Cessation
- 1987-02-04 ZA ZA87793A patent/ZA87793B/xx unknown
- 1987-02-04 NZ NZ219169A patent/NZ219169A/en unknown
- 1987-02-04 DK DK058387A patent/DK164202C/da not_active IP Right Cessation
- 1987-02-04 AU AU68292/87A patent/AU601712B2/en not_active Ceased
- 1987-02-05 PH PH34815A patent/PH24377A/en unknown
- 1987-02-05 KR KR870000912A patent/KR870007698A/ko not_active Ceased
1991
- 1991-07-08 GR GR91400966T patent/GR3002270T3/el unknown

Also Published As

Publication number	Publication date
DK164202C (da)	1992-10-19
NO169638C (no)	1992-07-22
FI870457L (fi)	1987-08-06
IL81472A0 (en)	1987-09-16
FI870457A0 (fi)	1987-02-03
IE59697B1 (en)	1994-03-23
JPS62209024A (ja)	1987-09-14
KR870007698A (ko)	1987-09-21
GR3002270T3 (en)	1992-12-30
ZA87793B (en)	1988-10-26
DE3603444A1 (de)	1987-08-06
NZ219169A (en)	1990-04-26
NO169638B (no)	1992-04-13
AU601712B2 (en)	1990-09-20
PT84243B (pt)	1989-09-14
FI86144C (fi)	1992-07-27
DK58387A (da)	1987-08-06
EP0231816B1 (de)	1991-05-29
NO870441D0 (no)	1987-02-04
HU196560B (en)	1988-12-28
ES2028796T3 (es)	1992-07-16
HUT43494A (en)	1987-11-30
PT84243A (de)	1987-03-01
CA1295242C (en)	1992-02-04
DK58387D0 (da)	1987-02-04
EP0231816A3 (en)	1987-09-23
DD284602A5 (de)	1990-11-21
IE870295L (en)	1987-08-05
NO870441L (no)	1987-08-06
AU6829287A (en)	1987-08-06
ATE63823T1 (de)	1991-06-15
DE3770280D1 (de)	1991-07-04
DK164202B (da)	1992-05-25
FI86144B (fi)	1992-04-15
EP0231816A2 (de)	1987-08-12

Publication	Publication Date	Title
ZA87793B (en)	1988-10-26	Formulations suitable for the stabilisation of alpha-interferon
IL85523A (en)	1992-11-15	Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it
CA2058428A1 (en)	1990-07-07	Analgesic formulations
ES2009216A6 (es)	1989-09-16	Metodo de preparar un derivado de interleucina-lalfa.
AU7076887A (en)	1987-10-29	Nasal administration of drugs
ZA928170B (en)	1993-11-15	Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid
PT779805E (pt)	2002-04-29	Libertacao sustentada de peptidos de composicoes farmaceuticas
DK0395329T3 (da)	1995-10-30	Sammensætning i form af et skum indeholdende 5-aminosalicylsyre til intrarektal administration
IE781032L (en)	1978-11-25	Pharmaceutical compositions
IL79816A0 (en)	1986-11-30	Pharmaceutical composition comprising a drug-polymer matrix
AU1518492A (en)	1992-06-25	Pharmaceutical compositions for transcutaneous administration
DK305087A (da)	1987-12-17	Buprenorphinholdigt farmaceutisk suppositorium
IL78604A (en)	1991-11-21	Process for the preparation of homogeneous,pure alpha-interferon,alpha-interferon produced thereby and pharmaceutical compositions containing it
GB2021409A (en)	1979-12-05	Pharmaceutical composition
AU581855B2 (en)	1989-03-09	1-(4'-alkylsulphonylphenyl)-2-amino-1, 3-propanediol n-substituted derivatives
IE56229B1 (en)	1991-05-22	2-piperazinyl-or-homopiperazinyl-quinazoline derivatives their production and pharmaceutical compositions containing them
AU581856B2 (en)	1989-03-09	1-(4'-alkylthiophenyl)-2-amino-1, 3-propanediol N-substituted derivatives
IL106289A (en)	2000-06-01	Phospholipid derivatives their preparation and pharmaceutical compositions containing them
GB1351437A (en)	1974-05-01	N-substituted amino acids having antiviral anti-inflammatory or anti-tumour activity
EP0355899A3 (en)	1991-03-20	Nucleotide derivatives
ES2091571T3 (es)	1996-11-01	Nuevos derivados peptidicos activos en los procesos de adhesion celular, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ATE102934T1 (de)	1994-04-15	Fluorierte flavon-essigsaeure.
AP9200405A0 (en)	1994-01-13	Pharmaceutical formulations comprised of micronised halofantrine.
ES2135424T3 (es)	1999-11-01	Composicion oral a base de ibuprofeno.
IT1241459B (it)	1994-01-17	Composizioni farmaceutiche per la somministrazione rettale di calcitonina