PH24741A - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number: PH24741A
Authority: PH; Philippines
Prior art keywords: indole derivatives; indole; derivatives
Prior art date: 1986-01-08

Application number

PH34698A

Other languages

English (en)

Inventor

Colin David Eldred

Keith Mills

Ian Harold Coates

David Edmund Bays

Michael Dennis Dowle

Colin Frederick Webb

Alexander William Oxford

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-08

Filing date

1987-01-08

Publication date

1990-10-01

1987-01-08 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1990-10-01 Publication of PH24741A publication Critical patent/PH24741A/en

Links

229940054051 antipsychotic indole derivative Drugs 0.000 title 1
150000002475 indoles Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PH34698A 1986-01-08 1987-01-08 Indole derivatives PH24741A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868600397A GB8600397D0 (en)	1986-01-08	1986-01-08	Chemical compounds

Publications (1)

Publication Number	Publication Date
PH24741A true PH24741A (en)	1990-10-01

Family

ID=10591074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH34698A PH24741A (en)	1986-01-08	1987-01-08	Indole derivatives

Country Status (23)

Country	Link
US (1)	US4855314A (fr)
EP (1)	EP0240096A1 (fr)
JP (1)	JPS62228056A (fr)
KR (1)	KR870007116A (fr)
CN (1)	CN1030409A (fr)
AU (1)	AU597325B2 (fr)
BE (1)	BE1000071A4 (fr)
CH (1)	CH672637A5 (fr)
DE (1)	DE3700408A1 (fr)
DK (1)	DK8787A (fr)
FI (1)	FI870062A7 (fr)
FR (1)	FR2595351B1 (fr)
GB (2)	GB8600397D0 (fr)
HU (1)	HU198685B (fr)
IL (1)	IL81201A (fr)
IT (1)	IT1205849B (fr)
LU (1)	LU86732A1 (fr)
NL (1)	NL8700026A (fr)
NO (1)	NO870075L (fr)
NZ (1)	NZ218868A (fr)
PH (1)	PH24741A (fr)
PT (1)	PT84075B (fr)
ZA (1)	ZA87105B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8530507D0 (en) *	1985-12-11	1986-01-22	Glaxo Group Plc	Chemical compounds
GB8600398D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
GB8724912D0 (en)	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
US5225431A (en) *	1987-10-23	1993-07-06	Burroughs Wellcome Co.	Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
GB8823731D0 (en) *	1988-10-10	1988-11-16	Smith Kline French Lab	Biologically active compounds
SI9111010B (sl) *	1990-06-07	2005-02-28	Astrazeneca Ab	3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
PL168919B1 (pl) *	1990-10-15	1996-05-31	Pfizer	Sposób wytwarzania nowych pochodnych indolu PL PL PL PL
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
CA2061520C (fr) *	1991-03-27	2003-04-22	Lawrence J. Daher	Systeme de delivrance accelerant l'effet et accroissant la puissance
CA2124206C (fr) *	1991-11-25	2001-02-27	John Eugene Macor	Derives indole
TW288010B (fr) *	1992-03-05	1996-10-11	Pfizer
RU2101283C1 (ru)	1992-04-07	1998-01-10	Пфайзер Инк.	Производные индола или их фармацевтически приемлемые соли
US6380233B1 (en)	1992-04-07	2002-04-30	Pfizer Inc	Indole derivatives as 5-HT1 agonists
GB9207930D0 (en) *	1992-04-10	1992-05-27	Pfizer Ltd	Indoles
AU670270B2 (en) *	1992-04-10	1996-07-11	Pfizer Inc.	Acylaminoindole derivatives as 5-HT1 agonists
GB9211277D0 (en)	1992-05-28	1992-07-15	Glaxo Group Inc	Pharmaceutical compositions
TW251284B (fr) *	1992-11-02	1995-07-11	Pfizer
FR2707639B1 (fr) *	1993-06-30	1995-10-13	Pf Medicament	Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) *	1993-08-09	1996-02-16	Pfizer	Derivados de acilaminoindol
CN1129933A (zh) *	1993-08-31	1996-08-28	辉瑞大药厂	5-芳基吲哚衍生物
US5468768A (en) *	1994-01-06	1995-11-21	Bristol-Myers Squibb Company	Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) *	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
FR2749846B1 (fr) *	1996-06-17	1998-09-11	Pf Medicament	Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
JP2004506714A (ja) *	2000-08-21	2004-03-04	パシフィック　コーポレーション	新規チオ尿素化合物及びこれを含有する薬学的組成物
BR0312176A (pt) *	2002-06-21	2005-04-05	Suven Life Sciences Ltd	Composto, composição farmaceutica, uso de um composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso, processo para a preparação de um composto, novo intermediario e processo para a preparação de um novo intermediario
MXPA04012834A (es) *	2002-06-21	2005-04-25	Suven Life Sciences Ltd	Arilalquil indoles novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen.
DE60309324T2 (de)	2002-06-21	2007-05-10	Suven Life Sciences Ltd.	Tetracyclische arylcarbonyl indole mit serotoninrezeptoraffinität als arzneimittel, verfahren zu ihrer herstellung und pharmazeutische zubereitungen
EP1581492B1 (fr) *	2002-11-28	2008-07-16	Suven Life Sciences Limited	Indoles n-arylsulfonyl-3-substitues presentant une affinite pour le recepteur de la serotonine, methode de preparation et composition pharmaceutique contenant ces indoles
KR100776118B1 (ko)	2002-11-28	2007-11-15	수벤 라이프 사이언시스 리미티드	엔-아릴술포닐-3-아미노알콕시인돌
AU2003292510B2 (en) *	2002-12-18	2009-04-23	Suven Life Sciences Limited	Tetracyclic 3-substituted indoles having serotonin receptor affinity
CA2508290C (fr) *	2002-12-20	2017-02-28	Ciba Specialty Chemicals Holding Inc.	Synthese d'amines et intermediaires pour cette synthese
EP2032532B8 (fr)	2006-06-12	2015-07-01	Novartis AG	Procédé de fabrication des sels de N-hydroxy-3-[4-[[[2-(2-méthyl-1H-indol-3-yl)éthyl]amino]méthyl]phényl]-2E-2-propénamide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3472870A (en) *	1966-08-29	1969-10-14	Mead Johnson & Co	Sulfonamidotryptamines
FR2334358A1 (fr) *	1975-12-12	1977-07-08	Sogeras	Nouveaux medicaments derives de l'indole
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
ZW19381A1 (en) *	1980-08-12	1983-03-09	Glaxo Group Ltd	Heterocyclic compounds
FR2488606A1 (fr) *	1980-08-12	1982-02-19	Glaxo Group Ltd	Derives indoliques, leur preparation et leurs applications en tant que medicaments
GB8332435D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8332437D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8332434D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Production of chemical compounds
GB8600398D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds

1986
- 1986-01-08 GB GB868600397A patent/GB8600397D0/en active Pending
1987
- 1987-01-08 LU LU86732A patent/LU86732A1/fr unknown
- 1987-01-08 BE BE8700003A patent/BE1000071A4/fr not_active IP Right Cessation
- 1987-01-08 JP JP62002589A patent/JPS62228056A/ja active Pending
- 1987-01-08 ZA ZA87105A patent/ZA87105B/xx unknown
- 1987-01-08 IT IT47507/87A patent/IT1205849B/it active
- 1987-01-08 DK DK008787A patent/DK8787A/da unknown
- 1987-01-08 PT PT84075A patent/PT84075B/pt not_active IP Right Cessation
- 1987-01-08 FI FI870062A patent/FI870062A7/fi not_active Application Discontinuation
- 1987-01-08 FR FR878700107A patent/FR2595351B1/fr not_active Expired - Fee Related
- 1987-01-08 PH PH34698A patent/PH24741A/en unknown
- 1987-01-08 AU AU67420/87A patent/AU597325B2/en not_active Ceased
- 1987-01-08 NO NO870075A patent/NO870075L/no unknown
- 1987-01-08 NZ NZ218868A patent/NZ218868A/xx unknown
- 1987-01-08 GB GB8700382A patent/GB2185020B/en not_active Expired - Fee Related
- 1987-01-08 DE DE19873700408 patent/DE3700408A1/de not_active Withdrawn
- 1987-01-08 CH CH45/87A patent/CH672637A5/fr not_active IP Right Cessation
- 1987-01-08 KR KR870000068A patent/KR870007116A/ko not_active Withdrawn
- 1987-01-08 NL NL8700026A patent/NL8700026A/nl not_active Application Discontinuation
- 1987-01-08 US US07/001,469 patent/US4855314A/en not_active Expired - Lifetime
- 1987-01-08 EP EP87300166A patent/EP0240096A1/fr not_active Withdrawn
- 1987-01-08 IL IL81201A patent/IL81201A/xx unknown
- 1987-07-03 HU HU873020A patent/HU198685B/hu not_active IP Right Cessation
- 1987-07-06 CN CN87105335A patent/CN1030409A/zh active Pending

Also Published As

Publication number	Publication date
LU86732A1 (fr)	1988-02-02
IL81201A0 (en)	1987-08-31
HU198685B (en)	1989-11-28
CN1030409A (zh)	1989-01-18
BE1000071A4 (fr)	1988-02-02
GB2185020A (en)	1987-07-08
NO870075D0 (no)	1987-01-08
CH672637A5 (fr)	1989-12-15
JPS62228056A (ja)	1987-10-06
DK8787D0 (da)	1987-01-08
NL8700026A (nl)	1987-08-03
GB8700382D0 (en)	1987-02-11
NZ218868A (en)	1990-04-26
HUT46891A (en)	1988-12-28
DE3700408A1 (de)	1987-07-09
GB8600397D0 (en)	1986-02-12
AU597325B2 (en)	1990-05-31
EP0240096A1 (fr)	1987-10-07
FI870062A7 (fi)	1987-07-09
IT1205849B (it)	1989-03-31
DK8787A (da)	1987-07-09
FI870062A0 (fi)	1987-01-08
FR2595351B1 (fr)	1990-07-13
AU6742087A (en)	1987-07-09
IL81201A (en)	1991-06-10
FR2595351A1 (fr)	1987-09-11
ZA87105B (en)	1987-09-30
IT8747507A0 (it)	1987-01-08
US4855314A (en)	1989-08-08
KR870007116A (ko)	1987-08-14
PT84075B (pt)	1989-07-31
GB2185020B (en)	1990-05-16
PT84075A (en)	1987-02-01
NO870075L (no)	1987-07-09

Publication	Publication Date	Title
GB2185020B (en)	1990-05-16	Indole derivatives
ZA885923B (en)	1989-07-26	Indole derivatives
PH22850A (en)	1989-01-19	Indole derivatives
EP0253500A3 (en)	1989-01-04	Acylanilide derivatives
ZA873583B (en)	1988-04-27	Imidazoquinolinylether derivatives
GB2168973B (en)	1988-02-03	Indole derivatives
ZA864770B (en)	1987-02-25	Indole derivatives
GB2186874B (en)	1990-02-07	Indole derivatives
ZA854355B (en)	1986-02-26	Indole derivatives
GB2191488B (en)	1990-03-28	Indole derivatives
EP0247381A3 (en)	1988-11-23	5-flurorouracil derivatives
ZA874622B (en)	1988-05-25	Indole derivatives
AR245109A1 (es)	1993-12-30	Un procedimiento para la preparacion de 5-fenil-5h-indeno/1,2-d/ pirimidina.
GB8620237D0 (en)	1986-10-01	Indole derivatives
EP0246002A3 (en)	1988-10-05	Alkenamide derivatives
GB2184444B (en)	1989-10-18	Indole derivatives
GB2184443B (en)	1989-10-18	Indole derivatives
IE861722L (en)	1986-12-27	Indole derivatives
GB8601960D0 (en)	1986-03-05	Indole derivatives
GB8614325D0 (en)	1986-07-16	Indole derivatives
ZA859244B (en)	1986-09-24	Indole derivatives
EP0244193A3 (en)	1989-01-18	Dihalogen-substituted thiocyanopyrimidine derivatives
ZA873138B (en)	1987-10-26	Indole derivative
GB8704063D0 (en)	1987-03-25	Indole derivatives
GB8706269D0 (en)	1987-04-23	Indole derivatives