PH25429A - 2-alkoxy-n-(1-azabicyclo£2.2.2|oct-3-yl)benzamides, thiobenzamides - Google Patents

2-alkoxy-n-(1-azabicyclo£2.2.2|oct-3-yl)benzamides, thiobenzamides

Info

Publication number: PH25429A
Authority: PH; Philippines
Prior art keywords: alkoxy; thiobenzamides; benzamides; azabicyclo; oct
Prior art date: 1987-09-04

Application number

PH37505A

Other languages

English (en)

Inventor

Robert John Naylor

Brenda Naylor

Original Assignee

Robins Co Inc A H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-04

Filing date

1988-09-05

Publication date

1991-07-01

1988-09-05 Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H

1991-07-01 Publication of PH25429A publication Critical patent/PH25429A/en

Links

229940054066 benzamide antipsychotics Drugs 0.000 title abstract 2
150000003936 benzamides Chemical class 0.000 title abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Chemical group 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
-1 amino, methylamino Chemical group 0.000 abstract 1
230000002932 anti-schizophrenic effect Effects 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PH37505A 1987-09-04 1988-09-05 2-alkoxy-n-(1-azabicyclo£2.2.2|oct-3-yl)benzamides, thiobenzamides PH25429A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB878720805A GB8720805D0 (en)	1987-09-04	1987-09-04	2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides

Publications (1)

Publication Number	Publication Date
PH25429A true PH25429A (en)	1991-07-01

Family

ID=10623261

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH37505A PH25429A (en)	1987-09-04	1988-09-05	2-alkoxy-n-(1-azabicyclo£2.2.2\|oct-3-yl)benzamides, thiobenzamides

Country Status (12)

Country	Link
US (1)	US4877794A (de)
EP (1)	EP0306345B1 (de)
JP (1)	JPH0269417A (de)
AT (1)	ATE88091T1 (de)
AU (1)	AU614768B2 (de)
CA (1)	CA1318595C (de)
DE (1)	DE3880240T2 (de)
DK (1)	DK492688A (de)
GB (1)	GB8720805D0 (de)
IL (1)	IL87662A0 (de)
PH (1)	PH25429A (de)
ZA (1)	ZA886586B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3878235T2 (de) *	1988-08-04	1993-06-03	Synthelabo	Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.)oct-3-yl)benzamide und thiobenzamide.
JPH0669963B2 (ja) *	1989-04-21	1994-09-07	サンド・アクチエンゲゼルシャフト	５ｈｔ▲下３▼受容体拮抗薬の治療的用途
US5236931A (en) *	1992-03-26	1993-08-17	A. H. Robins Company, Incorporated	2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol
US6479510B2 (en)	2000-08-18	2002-11-12	Pharmacia & Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
WO2002016357A2 (en)	2000-08-18	2002-02-28	Pharmacia & Upjohn Company	Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
JP2005504059A (ja) *	2001-08-24	2005-02-10	ファルマシアアンドアップジョンカンパニーリミティドライアビリティーカンパニー	疾患を処置するための置換アリール７−アザ［２．２．１］ビシクロヘプタン
EP1480977A2 (de)	2002-02-15	2004-12-01	PHARMACIA & UPJOHN COMPANY	Substituierte arylverbindungen zur behandlung von krankheiten
WO2003072578A1 (en) *	2002-02-20	2003-09-04	Pharmacia & Upjohn Company	Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity
FR2861076B1 (fr) *	2003-10-17	2006-01-06	Sanofi Synthelabo	Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique
EP2344636B1 (de)	2008-10-09	2017-12-06	Howard Hughes Medical Institute	Neue chimäre ligandgesteuerte ionenkanäle und anwendungsverfahren dafür

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7611713A (nl) *	1975-11-03	1977-05-05	Thomae Gmbh Dr K	Werkwijze voor de bereiding van verbindingen en preparaten met waardevolle farmacologische eigen- schappen.
FR2531083B1 (fr) *	1982-06-29	1986-11-28	Sandoz Sa	Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2529548A1 (fr) *	1982-07-02	1984-01-06	Delalande Sa	Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
US4593034A (en) *	1984-04-06	1986-06-03	A. H. Robins Company, Inc.	2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides
US4605652A (en) *	1985-02-04	1986-08-12	A. H. Robins Company, Inc.	Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
EP0201165B1 (de) *	1985-03-14	1994-07-20	Beecham Group Plc	Arzneimittel zur Behandlung von Emesis
GB8511988D0 (en) *	1985-05-11	1985-06-19	Beecham Group Plc	Compounds
DE3780276T2 (de) *	1986-12-16	1993-02-25	Robins Co Inc A H	Angstloesende n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide und -thiobenzamide.

1987
- 1987-09-04 GB GB878720805A patent/GB8720805D0/en active Pending
1988
- 1988-09-02 IL IL87662A patent/IL87662A0/xx unknown
- 1988-09-05 PH PH37505A patent/PH25429A/en unknown
- 1988-09-05 AT AT88308182T patent/ATE88091T1/de not_active IP Right Cessation
- 1988-09-05 DK DK492688A patent/DK492688A/da not_active Application Discontinuation
- 1988-09-05 ZA ZA886586A patent/ZA886586B/xx unknown
- 1988-09-05 JP JP63220559A patent/JPH0269417A/ja active Pending
- 1988-09-05 EP EP88308182A patent/EP0306345B1/de not_active Expired - Lifetime
- 1988-09-05 DE DE88308182T patent/DE3880240T2/de not_active Expired - Fee Related
- 1988-09-05 AU AU21834/88A patent/AU614768B2/en not_active Ceased
- 1988-09-06 CA CA000576593A patent/CA1318595C/en not_active Expired - Fee Related
- 1988-09-06 US US07/240,868 patent/US4877794A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH0269417A (ja)	1990-03-08
EP0306345A2 (de)	1989-03-08
GB8720805D0 (en)	1987-10-14
DK492688D0 (da)	1988-09-05
IL87662A0 (en)	1989-02-28
AU614768B2 (en)	1991-09-12
EP0306345B1 (de)	1993-04-14
US4877794A (en)	1989-10-31
DK492688A (da)	1989-03-05
ZA886586B (en)	1990-05-30
EP0306345A3 (en)	1989-06-14
CA1318595C (en)	1993-06-01
AU2183488A (en)	1989-03-09
DE3880240D1 (de)	1993-05-19
DE3880240T2 (de)	1993-10-28
ATE88091T1 (de)	1993-04-15

Publication	Publication Date	Title
ZA851381B (en)	1986-05-28	2-alkoxy-n-(1-azabicyclo/2.2.2/oct-3-yl)benzamides and thiobenzamides
PH25426A (en)	1991-07-01	Antischizoprenic-s-n(1-azabicyclo£2.2.2\|oct-3-yl)benzamides, thiobenzamides
PH25429A (en)	1991-07-01	2-alkoxy-n-(1-azabicyclo£2.2.2\|oct-3-yl)benzamides, thiobenzamides
EP0152236A3 (en)	1987-05-13	Aryloxymethylpyrrolidinols and piperidinols having antidepressant, antiarhythmic or hypotensive activity
IE893230L (en)	1990-04-07	Hydrocarbon substituted pyrrolidinones
AU2037088A (en)	1989-03-02	Naphthyridine antianaerobic compounds
AU7383087A (en)	1987-12-10	Fused imidazoheterocyclic compounds
TW349864B (en)	1999-01-11	Use of N-(pyridinyl)-1H-indol-a-amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders
AU634584B2 (en)	1993-02-25	Aroyl-ureas
GR851890B (de)	1985-12-09
GR3005011T3 (de)	1993-05-24