PH25496A - New vitamin d analogues - Google Patents

New vitamin d analogues

Info

Publication number
PH25496A
PH25496A PH34061A PH34061A PH25496A PH 25496 A PH25496 A PH 25496A PH 34061 A PH34061 A PH 34061A PH 34061 A PH34061 A PH 34061A PH 25496 A PH25496 A PH 25496A
Authority
PH
Philippines
Prior art keywords
analogues
new vitamin
vitamin
new
Prior art date
Application number
PH34061A
Other languages
English (en)
Inventor
Martin John Calverley
Ernst Torndal Binderup
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26289597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH25496(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858519502A external-priority patent/GB8519502D0/en
Priority to PCT/DK1986/000081 priority Critical patent/WO1987000834A1/en
Priority to EP86904788A priority patent/EP0227826B1/en
Priority to JP61504410A priority patent/JPH07100685B2/ja
Priority to KR1019870700233A priority patent/KR940010767B1/ko
Priority to DE8686904788T priority patent/DE3666587D1/de
Priority to US07/034,391 priority patent/US4866048A/en
Priority to AU61961/86A priority patent/AU603340B2/en
Priority to IE189486A priority patent/IE58545B1/en
Priority to CA000515024A priority patent/CA1307288C/en
Priority to GR862029A priority patent/GR862029B/el
Priority to ES8600822A priority patent/ES2000823A6/es
Priority to PT83119A priority patent/PT83119B/pt
Priority to PH34061A priority patent/PH25496A/en
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Priority to DK142987A priority patent/DK166617B1/da
Publication of PH25496A publication Critical patent/PH25496A/en
Priority to SG641/92A priority patent/SG64192G/en
Priority to HK634/92A priority patent/HK63492A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PH34061A 1985-08-02 1986-08-11 New vitamin d analogues PH25496A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
PCT/DK1986/000081 WO1987000834A1 (en) 1985-08-02 1986-07-14 Novel vitamin d analogues
EP86904788A EP0227826B1 (en) 1985-08-02 1986-07-14 Novel vitamin d analogues
JP61504410A JPH07100685B2 (ja) 1985-08-02 1986-07-14 新規ビタミンｄ類似体
KR1019870700233A KR940010767B1 (ko) 1985-08-02 1986-07-14 신규 비타민 d 동족체
DE8686904788T DE3666587D1 (en) 1985-08-02 1986-07-14 Novel vitamin d analogues
US07/034,391 US4866048A (en) 1985-08-02 1986-07-14 Novel vitamin D analogues
AU61961/86A AU603340B2 (en) 1985-08-02 1986-07-14 Novel vitamin d analogues
IE189486A IE58545B1 (en) 1985-08-02 1986-07-15 Novel vitamin d analogues
CA000515024A CA1307288C (en) 1985-08-02 1986-07-30 Chemical compounds
GR862029A GR862029B (en) 1985-08-02 1986-07-31 Chemical compounds
PT83119A PT83119B (pt) 1985-08-02 1986-08-01 Processo para a preparacao de uma nova classe de analogos da vitamina d e de composicoes farmaceuticas que os contem
ES8600822A ES2000823A6 (es) 1985-08-02 1986-08-01 Metodo para la produccion de compuestos analogos a la vitamina d
PH34061A PH25496A (en) 1985-08-02 1986-08-11 New vitamin d analogues
DK142987A DK166617B1 (da) 1985-08-02 1987-03-20 24-hydroxylerede d-vitamin-derivater og farmaceutiske praeparater indeholdende disse
SG641/92A SG64192G (en) 1985-08-02 1992-06-23 Novel vitamin d analogues
HK634/92A HK63492A (en) 1985-08-02 1992-08-20 Novel vitamin d analogues

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858519502A GB8519502D0 (en) 1985-08-02 1985-08-02 Chemical compounds
PH34061A PH25496A (en) 1985-08-02 1986-08-11 New vitamin d analogues

Publications (1)

Publication Number Publication Date
PH25496A true PH25496A (en) 1991-07-24

Family

ID=26289597

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34061A PH25496A (en) 1985-08-02 1986-08-11 New vitamin d analogues

Country Status (16)

Country Link
US (1) US4866048A (es)
EP (1) EP0227826B1 (es)
JP (1) JPH07100685B2 (es)
KR (1) KR940010767B1 (es)
AU (1) AU603340B2 (es)
CA (1) CA1307288C (es)
DE (1) DE3666587D1 (es)
DK (1) DK166617B1 (es)
ES (1) ES2000823A6 (es)
GR (1) GR862029B (es)
HK (1) HK63492A (es)
IE (1) IE58545B1 (es)
PH (1) PH25496A (es)
PT (1) PT83119B (es)
SG (1) SG64192G (es)
WO (1) WO1987000834A1 (es)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728643A (en) * 1984-11-02 1988-03-01 The General Hospital Corporation Method of treating psoriasis
GB2183156B (en) * 1985-03-14 1989-06-21 Chugai Pharmaceutical Co Ltd Composition for treating skin disease
FR2631025B1 (fr) * 1988-05-04 1991-04-12 Ire Medgenix Sa Nouveaux derives de la vitamine d3 et application aux dosages des metabolites de la vitamine d3
GB8816505D0 (en) * 1988-07-12 1988-08-17 Leo Pharm Prod Ltd Novel treatment
US4851401A (en) * 1988-07-14 1989-07-25 Wisconsin Alumni Research Foundation Novel cyclopentano-vitamin D analogs
GB8904154D0 (en) 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds
WO1991012238A1 (de) * 1990-02-06 1991-08-22 Schering Aktiengesellschaft Berlin Und Bergkamen Seitenketten-homologe vitamin-d-derivative, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische präparate sowie deren verwendung als arzneimittel
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
GB9015774D0 (en) * 1990-07-18 1990-09-05 Leo Pharm Prod Ltd Novel treatment
GB9017890D0 (en) 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
BR9106062A (pt) * 1990-09-21 1993-03-09 Lunar Corp Nova 1 alfa-hidroxi vitamina d4 e novos intermediarios e analogos
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
US6166000A (en) * 1991-01-08 2000-12-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-Dihydroxy vitamin . D.sub2
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5786348A (en) * 1991-01-08 1998-07-28 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
DE69233074T2 (de) * 1991-01-08 2004-03-18 Bone Care International Inc., Madison Verfahren zur Herstellung von 1-alpha-24-dihydroxy-Vitamin D2
US5182396A (en) * 1991-03-29 1993-01-26 Nisshin Flour Milling Co., Ltd. 1-hydroxyvitamin d derivatives
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DK0521550T3 (da) * 1991-07-05 1996-11-04 Duphar Int Res Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor
US5182393A (en) * 1991-08-09 1993-01-26 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
US5225569A (en) * 1991-08-09 1993-07-06 Hoffmann-La Roche Inc. Process for precursors to calcitriol and related compounds
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same
US5288408A (en) * 1992-10-26 1994-02-22 Chemical Industry Consultants, Inc. Method of gelatin recovery and purification from encapsulation processes
US5247104A (en) * 1992-11-04 1993-09-21 Wisconsin Alumni Research Foundation Preparation of 1α, 24-dihydroxyvitamin D analogs
USRE39706E1 (en) * 1993-01-15 2007-06-26 Leo Pharma A/S Crystalline form of a vitamin D analogue
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
DE4328217C2 (de) * 1993-08-21 1996-01-11 Lohmann Therapie Syst Lts Therapeutisches System zur Behandlung der Psoriasis
US5763429A (en) * 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US5565589A (en) * 1993-11-03 1996-10-15 Wisconsin Alumni Research Foundation 17-formyl-5,6-trans-vitamin D compounds
US5373004A (en) * 1993-11-24 1994-12-13 Wisconsin Alumni Research Foundation 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
AU700668B2 (en) * 1994-07-18 1999-01-14 Bone Care International, Inc. Synthesis of 1alpha-hydroxy vitamin D
DK128494A (da) * 1994-11-08 1996-05-09 Edel K Seidenschnur Behandling af keratinøse og psoriatiske sygdomstilstande med neglelak indeholdende vitamin D metabolit, eller derivat, og/eller vitamin A derivat
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
CH690075A5 (de) * 1995-07-11 2000-04-14 Cerbios Pharma Sa Verfahren zur Herstellung von 9,10-Secocholesta-5, 7, 10 (19)-trienen durch Reduktion der Epoxide.
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
CA2279590A1 (en) 1997-02-13 1998-08-20 Bone Care International, Inc. Targeted therapeutic delivery of vitamin d compounds
DE19744127B4 (de) 1997-10-01 2006-10-05 Schering Ag Neue Vitamin D-Derivate mit Cyclopropylringen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung sowie ihre Verwendung zur Herstellung von Arzneimitteln
WO1999029325A1 (en) 1997-12-09 1999-06-17 Chugai Seiyaku Kabushiki Kaisha Lotions containing vitamin d3 derivatives
EP1064000B1 (en) 1998-03-27 2011-07-06 Oregon Health & Science University Vitamin d and its analogs in the treatment of tumors and other hyperproliferative disorders
US6552009B2 (en) * 1998-07-16 2003-04-22 Gentrix Llc Compositions and methods of treating abnormal cell proliferation
US20010002396A1 (en) * 1998-07-16 2001-05-31 Charles Achkar Compositions and methods of treating skin conditions
US8263580B2 (en) * 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
US6410746B1 (en) 1999-04-27 2002-06-25 Research Foundation Of State University Of New York, The Metal cataltsts and methods for making and using same
US6617681B1 (en) * 1999-06-28 2003-09-09 Intel Corporation Interposer and method of making same
US6524623B1 (en) 1999-11-12 2003-02-25 Milton Hodosh Therapeutic compositions and methods of use thereof
WO2002006218A2 (en) * 2000-07-18 2002-01-24 Bone Care International, Inc. STABILIZED 1α-HYDROXY VITAMIN D
WO2003018184A2 (en) 2001-08-27 2003-03-06 The Research Foundation Of State University Of New York Solid support dirhodium catalyst compositions and methods for making and using same
AU2002331753A1 (en) 2001-08-27 2003-03-10 The Research Foundation Of State University Of New York Dirhodium catalyst compositions and methods for using same
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
MXPA04005260A (es) * 2001-12-03 2005-03-23 Novacea Inc Composiciones farmaceuticas que comprenden compuestos activos de vitamina d.
EP1470220B1 (en) 2002-01-10 2011-10-05 Teva Pharmaceutical Industries, Ltd. Selective enzymatic esterification and solvolysis of epimeric vitamin d analog and separation of the epimers
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
CA2481909C (en) * 2002-04-11 2013-07-02 Instytut Farmaceutyczny Preparation of 24-alkyl analogs of cholecalciferol
EP1461314A1 (en) * 2002-06-13 2004-09-29 Teva Pharmaceutical Industries Limited Epimerization of analogs of vitamin d
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US7351869B2 (en) * 2002-11-18 2008-04-01 Teva Pharmaceutical Industries Ltd Crystallization method for purification of calcipotriene
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
WO2005007838A1 (ja) 2003-06-27 2005-01-27 Asahi Kasei Kabushiki Kaisha 細胞分化抑制剤、これを用いた細胞培養方法、培養液及び培養された細胞株
JP4886511B2 (ja) * 2003-07-30 2012-02-29 ライジェル ファーマシューティカルズ， インコーポレイテッド ２，４−ピリミジンジアミン化合物による自己免疫疾患の治療または予防方法
US7205006B2 (en) * 2003-09-25 2007-04-17 Prime Pharmaceutical Corporation Mahonia aquifolium extract, extraction process and pharmaceutical composition containing the same
RU2380359C2 (ru) * 2004-03-18 2010-01-27 Лео Фарма А/С Стереоселективный синтез аналогов витамина д
US8362287B2 (en) 2004-03-18 2013-01-29 Leo Pharma A/S Stereoselective synthesis of vitamin D analogues
EP1735276B1 (en) * 2004-04-02 2011-02-16 Leo Pharma A/S Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
TWI318203B (en) * 2004-09-01 2009-12-11 Leo Pharma As Epimerization of allylic alcohols
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
JP2006204292A (ja) * 2004-12-27 2006-08-10 Asahi Kasei Corp ヒト胚性幹細胞分化抑制剤
CA2608021A1 (en) * 2005-05-10 2006-11-16 Dermipsor Ltd. Compositions and methods for skin care
CA2608023C (en) 2005-05-10 2015-08-18 Dermipsor Ltd. Compositions comprising calcipotriol and nicotinamide for treating hyperproliferative epidermal diseases
CA2611147C (en) 2005-06-01 2013-04-09 Stiefel Research Australia Pty Ltd. Topical emulsion formulation
US7700798B1 (en) 2005-06-08 2010-04-20 The Research Foundation Of State University Of New York Erogorgiaene congeners and methods and intermediates useful in the preparation of same
US7816536B2 (en) * 2005-06-10 2010-10-19 The Research Foundation Of State University Of New York 4-substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles and methods for making same
JP2008543855A (ja) 2005-06-13 2008-12-04 ライジェル ファーマシューティカルズ， インコーポレイテッド 変形性骨疾患を処置するための方法および組成物
CA2612408A1 (en) * 2005-06-15 2006-12-28 Apollo Pharmaceutical, Inc. Pharmaceutical composition comprising a mahonia aquifolium extract for the treatment of psoriasis
PT1734251E (pt) * 2005-06-17 2007-03-30 Magneti Marelli Powertrain Spa Injector de combustível
TW200714580A (en) * 2005-10-14 2007-04-16 Formosa Lab Inc Process for preparing vitamin D analogs
US7385064B1 (en) 2005-11-30 2008-06-10 The Research Foundation Of State University Of New York Catalysts for use in enantioselective synthesis
BRPI0621471A2 (pt) 2006-03-17 2012-09-11 Leo Pharma As métodos de isomerização de uma solução de um derivado de vitamina d, para produzir e preparar calcipotriol ou monoidrato de calcipotriol, e para a fabricação de uma formulação farmacêutica ou medicamento, e, uso de um reator foto-reator de fluxo direto ou foto-reator de fluxo contìnuo
US20080051375A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
CA2838089A1 (en) 2006-08-25 2008-02-28 Cougar Biotechnology, Inc. Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
US20080051380A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
KR20090039833A (ko) * 2006-08-29 2009-04-22 테바 파마슈티컬 인더스트리즈 리미티드 비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물
ES2272198B1 (es) * 2006-12-28 2008-06-01 Laboratorios Viñas S.A. Procedimiento para la obtencion de hidrato de calcipotriol.
WO2009009132A1 (en) * 2007-07-12 2009-01-15 Cougar Biotechnology, Inc. Use of 17alpha-hydroxylase/c17, 20-lyase inhibitors for the treatment of cancer
US8716334B2 (en) * 2008-06-17 2014-05-06 Ben Gurion University Of The Negev Research And Development Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
SG2014006324A (en) 2009-01-27 2014-03-28 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
US20120184514A1 (en) * 2009-07-01 2012-07-19 Vitamin Derivatives Inc. Vitamin d compounds and methods for preparing same
CN102655869B (zh) 2009-08-14 2016-08-10 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
WO2011079249A2 (en) * 2009-12-23 2011-06-30 Glycomyr, Inc. Use of vitamin d glycosides and sulfates for treatment of disease
US8987235B2 (en) 2011-05-17 2015-03-24 Wisconsin Alumni Research Foundation N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs and their uses
CN103508999B (zh) 2013-10-12 2015-05-13 浙江海正药业股份有限公司 马沙骨化醇的合成中间体及其制备方法和用途
CN103694156B (zh) * 2014-01-07 2015-09-02 成都医路康医学技术服务有限公司 一种银屑病治疗药物钙泊三醇的制备方法
CN105348164B (zh) * 2015-10-29 2017-03-29 无锡福祈制药有限公司 一种1α‑羟基维生素D2的制备方法
WO2017209934A1 (en) 2016-05-13 2017-12-07 Case Western Reserve University Autophagy activators for treating or preventing skin injury
CN107501150A (zh) * 2016-06-14 2017-12-22 江苏吉贝尔药业股份有限公司 两种他卡西醇中间体的制备方法
MX2019001224A (es) 2016-07-29 2019-06-03 Janssen Pharmaceutica Nv Metodos para tratar el cancer de prostata.
CN110156836A (zh) * 2019-06-10 2019-08-23 成家钢 一种环丙基羰基亚甲基三苯基磷的制备方法
CN111662221B (zh) * 2020-06-29 2022-04-19 重庆华邦胜凯制药有限公司 一种卡泊三醇杂质的制备方法
CN115177586A (zh) * 2022-08-31 2022-10-14 江苏知原药业股份有限公司 一种卡泊三醇组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
JPS5945675B2 (ja) * 1978-01-16 1984-11-07 ウイスコンシン・アラムナイ・リサ−チ・フオンデ−シヨン １−オキソシクロビタミンｄ誘導体
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4335120A (en) * 1979-03-21 1982-06-15 Hoffmann-La Roche Inc. Administration of biologically active vitamin D3 and vitamin D2 materials
JPS57109765A (en) * 1980-12-27 1982-07-08 Wisconsin Alumni Res Found Preparation of 1-hydroxylated vitamin d compound from 5,6-trans-vitamin d compound
JPS57149224A (en) * 1981-03-13 1982-09-14 Chugai Pharmaceut Co Ltd Tumor-suppressing agent
US4442093A (en) * 1981-05-15 1984-04-10 Kureha Kagaku Kogyo Kabushiki Kaisha Method for administering 24,25-dihydroxycholecalciferol to persons suffering from hypercalcemia
JPS58208224A (ja) * 1982-05-28 1983-12-03 Kureha Chem Ind Co Ltd 抗腫瘍剤
JPS59104358A (ja) * 1982-12-03 1984-06-16 Teijin Ltd １α，２４−ジヒドロキシコレカルシフエロ−ルの一水塩及びその製造法
US4610978A (en) * 1983-03-22 1986-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same
JPS59186956A (ja) * 1983-04-07 1984-10-23 Teijin Ltd ２４−ヒドロキシ−２５−デヒドロビタミンｄ↓３類、その製造法及びそれを有効成分とするカルシウム調節剤
US4728643A (en) * 1984-11-02 1988-03-01 The General Hospital Corporation Method of treating psoriasis
US4661294A (en) * 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D

Also Published As

Publication number Publication date
EP0227826A1 (en) 1987-07-08
IE58545B1 (en) 1993-10-06
AU603340B2 (en) 1990-11-15
DK166617B1 (da) 1993-06-21
JPS63500661A (ja) 1988-03-10
IE861894L (en) 1987-02-02
DK142987A (da) 1987-03-20
ES2000823A6 (es) 1988-03-16
WO1987000834A1 (en) 1987-02-12
US4866048A (en) 1989-09-12
PT83119B (pt) 1989-03-30
SG64192G (en) 1992-09-04
JPH07100685B2 (ja) 1995-11-01
CA1307288C (en) 1992-09-08
AU6196186A (en) 1987-03-05
DE3666587D1 (en) 1989-11-30
GR862029B (en) 1986-12-24
KR870700600A (ko) 1987-12-30
DK142987D0 (da) 1987-03-20
KR940010767B1 (ko) 1994-11-11
HK63492A (en) 1992-08-28
EP0227826B1 (en) 1989-10-25
PT83119A (en) 1986-09-01

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