PH26833A - Anticonvulsant agents - Google Patents

Anticonvulsant agents Download PDF

Info

Publication number
PH26833A
PH26833A PH40739A PH40739A PH26833A PH 26833 A PH26833 A PH 26833A PH 40739 A PH40739 A PH 40739A PH 40739 A PH40739 A PH 40739A PH 26833 A PH26833 A PH 26833A
Authority
PH
Philippines
Prior art keywords
methyl
compound
employing
chloro
dimethylphenyl
Prior art date
Application number
PH40739A
Other languages
English (en)
Inventor
David Wayne Robertson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PH26833A publication Critical patent/PH26833A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH40739A 1989-06-30 1990-06-27 Anticonvulsant agents PH26833A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/374,680 US4973597A (en) 1989-06-30 1989-06-30 Anticonvulsant agents

Publications (1)

Publication Number Publication Date
PH26833A true PH26833A (en) 1992-11-05

Family

ID=23477786

Family Applications (1)

Application Number Title Priority Date Filing Date
PH40739A PH26833A (en) 1989-06-30 1990-06-27 Anticonvulsant agents

Country Status (15)

Country Link
US (1) US4973597A (ja)
EP (1) EP0405931A3 (ja)
JP (1) JPH0344373A (ja)
KR (1) KR910000645A (ja)
CN (1) CN1048382A (ja)
AU (1) AU623024B2 (ja)
CA (1) CA2019964A1 (ja)
FI (1) FI903283A7 (ja)
HU (1) HUT54652A (ja)
IE (1) IE902385A1 (ja)
NZ (1) NZ234266A (ja)
PH (1) PH26833A (ja)
PT (1) PT94534A (ja)
RU (1) RU1836351C (ja)
ZA (1) ZA905018B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4231519A1 (de) * 1992-09-21 1994-03-24 Basf Ag Cyclohex(en)ylcarbonsäureamide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen
PT1035115E (pt) 1999-02-24 2005-01-31 Hoffmann La Roche Derivados de 4-fenilpiridina e a sua utilizacao como antagonistas do receptor nk-1
US7288658B2 (en) 2003-07-15 2007-10-30 Hoffmann-La Roche Inc. Process for preparation of pyridine derivatives
CN103893145A (zh) 2005-09-23 2014-07-02 弗·哈夫曼-拉罗切有限公司 新型制剂
EP2608672B1 (en) * 2010-08-23 2020-12-16 Syntrix Biosystems, Inc. Aminopyridine- and aminopyrimidinecarboxamides as cxcr2 modulators

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2799679A (en) * 1955-04-28 1957-07-16 Bofors Ab Process of preparing amides of heterocyclic carboxylic acids
FR1604911A (en) * 1965-04-20 1971-05-15 Amides and basic esters of 2-chloronicotinic acid - - with antiinflammatory and antispasmodic activity
US3462532A (en) * 1967-08-28 1969-08-19 Dow Chemical Co Controlling gastropods with nicotinanilide or alkylaryl nicotinamide gastropodicides
FR2088145A1 (en) * 1970-05-22 1972-01-07 Anvar 6-hydroxy nicotinic acid derivs - with local anaesthetic activity
DE2417216A1 (de) * 1974-04-09 1975-11-06 Basf Ag Fungizide
US4004029A (en) * 1974-05-13 1977-01-18 The Upjohn Company Compositions and method for treating epilepsy and convulsions
ES428449A1 (es) * 1974-07-20 1976-08-16 Hermes Sa Lab Procedimiento para la obtencion de un nuevo derivado de la 2-piridona.
US4031105A (en) * 1974-07-20 1977-06-21 Laboratorios Hermes, S.A. 3-(N-2', 6'xylyl)-carboxamide pyridone-2
IT1043918B (it) * 1974-09-05 1980-02-29 Sigma Tau Ind Farmaceuti Ammidi fluorurate dell acido nicotinico e procedimento per loro preparazione
DE2611601A1 (de) * 1976-03-19 1977-09-22 Basf Ag Nicotinsaeureanilide
SE7607114L (sv) * 1976-06-22 1977-12-23 Bofors Ab Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid
US4361572A (en) * 1981-12-21 1982-11-30 Chugai Seiyaku Kabushiki Kaisha Tetrahydronicotinamide derivative, pharmaceutical compositions and use
US4684748A (en) * 1985-07-26 1987-08-04 Eli Lilly And Company Anticonvulsant agents
US4638014A (en) * 1985-08-26 1987-01-20 Research Corporation Anticonvulsant method and formulations
US4835181A (en) * 1987-02-18 1989-05-30 Eli Lilly And Company Anticonvulsant agents using cyano dimethylphenyl benzamides
US4743610A (en) * 1987-03-16 1988-05-10 American Cyanamid Company N-[ω(3-pyridinyl)alkyl]benzamides, useful as thromboxane synthetase enzyme and/or cardioprotective agents
US4861891A (en) * 1988-08-31 1989-08-29 Pfizer Inc. Antidepressant N-substituted nicotinamide compounds

Also Published As

Publication number Publication date
IE902385A1 (en) 1991-06-19
RU1836351C (ru) 1993-08-23
EP0405931A2 (en) 1991-01-02
IE902385L (en) 1990-12-30
NZ234266A (en) 1992-04-28
PT94534A (pt) 1991-02-08
JPH0344373A (ja) 1991-02-26
CA2019964A1 (en) 1990-12-31
EP0405931A3 (en) 1991-09-25
KR910000645A (ko) 1991-01-29
CN1048382A (zh) 1991-01-09
AU5799190A (en) 1991-01-03
FI903283A7 (fi) 1990-12-31
ZA905018B (en) 1992-02-26
FI903283A0 (fi) 1990-06-28
HU904027D0 (en) 1990-12-28
US4973597A (en) 1990-11-27
AU623024B2 (en) 1992-04-30
HUT54652A (en) 1991-03-28

Similar Documents

Publication Publication Date Title
KR870000741B1 (ko) 벤젠설폰 아미도 유도체의 제조 방법
EP0923542B1 (en) Aryl substituted cyclic amines as selective dopamine d3 ligands
PT889875E (pt) Derivados de acidos ciclopropilalcanoicos
JP2002511836A (ja) 化合物および方法
KR20000030003A (ko) 인터루킨-8수용체길항제
PL98616B1 (pl) Sposob wytwarzania trojpodstawionych guanidyn
AU6354300A (en) Phosphate transport inhibitors
CZ277693B6 (en) Anti-atherosclerotic active compounds, pharmaceuticals containing such compounds and process for preparing thereof
US6197797B1 (en) Cyanoguanidines as cell proliferation inhibitors
AU715493B2 (en) Selective beta 3 adrenergic agonists
PH26833A (en) Anticonvulsant agents
US4835181A (en) Anticonvulsant agents using cyano dimethylphenyl benzamides
EP0194884B1 (en) Anticonvulsant agents
AU7915100A (en) Use of carbonylamino derivatives against cns disorders
US4684748A (en) Anticonvulsant agents
EP0213924B1 (en) P-acylaminobenzamides
US4981866A (en) Anticonvulsant agents
US4939163A (en) Anticonvulsant agents
US4629731A (en) Anticonvulsant N-(2,6-disubstituted aromatic)-n'-pyridinyl ureas
US5407936A (en) Benzimidazole derivative, process for preparing the same, antiemetic agent containing the same as active ingredient and intermediate compound for preparing the same
JPS60202884A (ja) ２‐アリールイミダゾ［４，５‐ｃ］ピリジン類
US3351529A (en) Sydnonimine pharmaceutical compositions
US4962116A (en) N-(2,6-disubstituted aromatic)-N'-pyridinyl ureas
IE841918L (en) N-aromatic-n-pyridinyl ureas
JPH09504787A (ja) 抗不整脈活性を有する複素環カルボキサミド誘導体