PH26967A - 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity - Google Patents

5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity Download PDF

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Publication number
PH26967A
PH26967A PH38328A PH38328A PH26967A PH 26967 A PH26967 A PH 26967A PH 38328 A PH38328 A PH 38328A PH 38328 A PH38328 A PH 38328A PH 26967 A PH26967 A PH 26967A
Authority
PH
Philippines
Prior art keywords
carbon atoms
alkyl
substituted
compound according
phenyl
Prior art date
Application number
PH38328A
Other languages
English (en)
Inventor
Ish K Khanna
Roger Nosal
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/167,671 external-priority patent/US4914108A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of PH26967A publication Critical patent/PH26967A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH38328A 1988-03-14 1989-03-14 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity PH26967A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/167,671 US4914108A (en) 1988-03-14 1988-03-14 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US07/317,871 US5019581A (en) 1988-03-14 1989-03-06 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity

Publications (1)

Publication Number Publication Date
PH26967A true PH26967A (en) 1992-12-28

Family

ID=26863369

Family Applications (1)

Application Number Title Priority Date Filing Date
PH38328A PH26967A (en) 1988-03-14 1989-03-14 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity

Country Status (15)

Country Link
US (1) US5019581A (de)
EP (1) EP0344414B1 (de)
JP (1) JP2714426B2 (de)
KR (1) KR890014537A (de)
AT (1) ATE112774T1 (de)
AU (1) AU625058B2 (de)
CA (1) CA1337072C (de)
DE (1) DE68918755T2 (de)
DK (1) DK169872B1 (de)
ES (1) ES2061753T3 (de)
FI (1) FI91407C (de)
IL (1) IL89588A0 (de)
NO (1) NO169965C (de)
NZ (1) NZ228336A (de)
PH (1) PH26967A (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302601A (en) * 1988-03-14 1994-04-12 G. D. Searle & Co. 5-substituted imidazo[4,5-c]pyridines
US5227384A (en) * 1988-03-14 1993-07-13 G. D. Searle & Co. 5-substituted [4,5-c] imidazopyridines and pharmaceutical use thereof
US4990518A (en) * 1989-09-13 1991-02-05 G. D. Searle & Co. Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines
GB9116056D0 (en) * 1991-07-24 1991-09-11 British Bio Technology Compounds
US5223539A (en) * 1991-11-22 1993-06-29 G. D. Searle & Co. N,n-di-alkyl(phenoxy)benzamide derivatives
US5208242A (en) * 1992-08-26 1993-05-04 G. D. Searle & Co. 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5262426A (en) * 1993-01-22 1993-11-16 G. D. Searle & Co. N,N'-cycloalkyl/alkyl carboxamide 4H-imidazo-[4,5-b]pyridine compounds as PAF antagonists
US5360907A (en) * 1993-06-14 1994-11-01 G.D. Searle & Co. Pyrrolo[3,2-B]pyridinylalkyl benzamide derivatives
US5496855A (en) * 1995-01-27 1996-03-05 Smithkline Beecham Corp. Anti-inflammatory compounds
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
JP4970048B2 (ja) * 2003-12-22 2012-07-04 カトリーケ・ウニフェルジテイト・ルーベン・カー・イュー・ルーベン・アール・アンド・ディ イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス治療の方法
DE602005013580D1 (de) * 2004-12-21 2009-05-07 Leuven K U Res & Dev Imidazoä4,5-cüpyridinverbindung und verfahren zur antiviralen behandlung
TW200808695A (en) * 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
TWI360549B (en) * 2006-07-07 2012-03-21 Gilead Sciences Inc Novel pyridazine compound and use thereof
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
ZA832938B (en) * 1982-05-03 1984-12-24 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
IL89588A0 (en) 1989-09-10
FI91407B (fi) 1994-03-15
NO169965B (no) 1992-05-18
NO891058L (no) 1989-09-15
AU3127089A (en) 1989-09-14
DE68918755D1 (de) 1994-11-17
DK121189D0 (da) 1989-03-13
JPH01316378A (ja) 1989-12-21
DE68918755T2 (de) 1995-03-09
AU625058B2 (en) 1992-07-02
NO891058D0 (no) 1989-03-13
US5019581A (en) 1991-05-28
FI891200A7 (fi) 1989-09-15
NO169965C (no) 1992-08-26
ATE112774T1 (de) 1994-10-15
NZ228336A (en) 1992-01-29
KR890014537A (ko) 1989-10-24
DK121189A (da) 1989-09-15
EP0344414B1 (de) 1994-10-12
CA1337072C (en) 1995-09-19
ES2061753T3 (es) 1994-12-16
DK169872B1 (da) 1995-03-20
EP0344414A1 (de) 1989-12-06
FI891200A0 (fi) 1989-03-14
FI91407C (fi) 1994-06-27
JP2714426B2 (ja) 1998-02-16

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