PH27359A - Process for cyclic amino acid anticonvulsant compounds - Google Patents
Process for cyclic amino acid anticonvulsant compoundsInfo
- Publication number
- PH27359A PH27359A PH41066A PH41066A PH27359A PH 27359 A PH27359 A PH 27359A PH 41066 A PH41066 A PH 41066A PH 41066 A PH41066 A PH 41066A PH 27359 A PH27359 A PH 27359A
- Authority
- PH
- Philippines
- Prior art keywords
- cyclic amino
- amino acid
- anticonvulsant compounds
- acid anticonvulsant
- compounds
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- -1 cyclic amino acid Chemical class 0.000 title abstract 2
- 230000001773 anti-convulsant effect Effects 0.000 title 1
- 239000001961 anticonvulsive agent Substances 0.000 title 1
- 229960003965 antiepileptics Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/10—Formation of amino groups in compounds containing carboxyl groups with simultaneously increasing the number of carbon atoms in the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/12—Formation of amino and carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Catalysts (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PH45082A PH30922A (en) | 1989-08-25 | 1992-10-12 | Process for cyclic amino acid anticonvulsant compound. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39905689A | 1989-08-25 | 1989-08-25 | |
| US07/564,623 US5132451A (en) | 1989-08-25 | 1990-08-10 | Process for cyclic amino acid anticonvulsant compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH27359A true PH27359A (en) | 1993-06-21 |
Family
ID=27016485
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH41066A PH27359A (en) | 1989-08-25 | 1990-08-22 | Process for cyclic amino acid anticonvulsant compounds |
| PH45082A PH30922A (en) | 1989-08-25 | 1992-10-12 | Process for cyclic amino acid anticonvulsant compound. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH45082A PH30922A (en) | 1989-08-25 | 1992-10-12 | Process for cyclic amino acid anticonvulsant compound. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5693845A (de) |
| EP (1) | EP0414262B1 (de) |
| JP (1) | JP2945728B2 (de) |
| AT (1) | ATE114637T1 (de) |
| AU (2) | AU633612B2 (de) |
| CA (1) | CA2023874A1 (de) |
| DE (1) | DE69014480T2 (de) |
| DK (1) | DK0414262T3 (de) |
| ES (1) | ES2065446T3 (de) |
| FI (1) | FI107914B (de) |
| IE (1) | IE66824B1 (de) |
| MY (1) | MY106864A (de) |
| NO (1) | NO179407C (de) |
| NZ (1) | NZ235044A (de) |
| PH (2) | PH27359A (de) |
| PT (1) | PT95097B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894476A (en) * | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
| FI905584L (fi) * | 1989-11-16 | 1991-05-17 | Lonza Ag | Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra. |
| CA2411787C (en) * | 2000-06-16 | 2007-03-20 | Teva Pharmaceuticals Industries Ltd. | Stable gabapentin having ph within a controlled range |
| CA2410867C (en) | 2000-06-16 | 2003-12-09 | Claude Singer | Stable gabapentin containing more than 2o ppm of chlorine ion |
| US20030119908A1 (en) * | 2001-12-21 | 2003-06-26 | Zambon Group S.P.A. | Stable gabapentin compositions |
| CA2528388A1 (en) * | 2003-06-19 | 2004-12-23 | Pfizer Products Inc. | Biocatalytic preparation of 1-cyanocyclohexaneacetic acid |
| GB0416228D0 (en) | 2004-07-20 | 2004-08-25 | Sandoz Ind Products S A | Process for the preparation of gabapentin |
| CN101484413B (zh) | 2006-06-30 | 2014-05-14 | Zach系统股份公司 | 制备加巴喷丁的方法 |
| JP4872950B2 (ja) | 2008-03-05 | 2012-02-08 | ソニー株式会社 | 非水電解質二次電池 |
| WO2015144825A1 (en) | 2014-03-27 | 2015-10-01 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Oral liquid pharmaceutical solution of gabapentin |
| CN107235850B (zh) * | 2017-05-31 | 2019-07-26 | 浙江工业大学 | 利用1-氰基环己基乙酸直接合成加巴喷丁的方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2264354A (en) * | 1937-12-22 | 1941-12-02 | Ig Farbenindustrie Ag | Addition products of dienes and unsaturated esters, ketones, or nitriles |
| US2467927A (en) * | 1947-05-29 | 1949-04-19 | Goodrich Co B F | Preparation of monomeric alkyl alpha-cyano-acrylates |
| US2502412A (en) * | 1948-02-07 | 1950-04-04 | Goodrich Co B F | Preparation of vinylidene cyanide by pyrolysis of novel 4, 4-disubstituted cyclohexenes |
| US2575376A (en) * | 1949-10-21 | 1951-11-20 | Gen Mills Inc | Formyl cyclohexene nitriles and esters |
| DE1445664A1 (de) * | 1963-07-04 | 1969-11-27 | Klinke Desitin Werk | Verfahren zur Herstellung von alpha,alpha-disubstituierten Succinimiden |
| JPS4822692B1 (de) * | 1963-12-24 | 1973-07-07 | ||
| US3515740A (en) * | 1967-02-20 | 1970-06-02 | Orville D Frampton | Cyano cyclohexenyl compounds |
| DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
| GB1478224A (en) * | 1975-01-24 | 1977-06-29 | Science Union & Cie | Dispiroalkanes processes for their preparation and pharma ceutical compositions containing them |
| DE2557220A1 (de) * | 1975-12-19 | 1977-06-23 | Goedecke Ag | N-substituierte spirolactame |
| DE2611690A1 (de) * | 1976-03-19 | 1977-09-22 | Goedecke Ag | Cyclische sulfonyloxyimide |
| DE2626467C2 (de) * | 1976-06-12 | 1984-11-22 | Gödecke AG, 1000 Berlin | 1-(N-Isopropylaminomethyl)-cyclohexanessigsäure, Verfahren zu deren Herstellung und diese Verbindung enthaltende Arzneimittel |
| US4226802A (en) * | 1979-10-29 | 1980-10-07 | Zoecon Corporation | 2-(4-Trifluoromethylphenylamino)-3-methylbutanoic acid esters and intermediates therefor |
| GB8606255D0 (en) * | 1986-03-13 | 1986-04-16 | Wyeth John & Brother Ltd | Nitriles |
| US4894476A (en) * | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
| YU162789A (en) * | 1988-09-01 | 1990-12-31 | Lonza Ag | 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones |
| DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
-
1990
- 1990-08-22 PH PH41066A patent/PH27359A/en unknown
- 1990-08-22 FI FI904164A patent/FI107914B/fi active IP Right Grant
- 1990-08-22 MY MYPI90001406A patent/MY106864A/en unknown
- 1990-08-22 AU AU61247/90A patent/AU633612B2/en not_active Ceased
- 1990-08-23 CA CA002023874A patent/CA2023874A1/en not_active Abandoned
- 1990-08-24 NO NO903732A patent/NO179407C/no not_active IP Right Cessation
- 1990-08-24 EP EP90116264A patent/EP0414262B1/de not_active Expired - Lifetime
- 1990-08-24 DK DK90116264.4T patent/DK0414262T3/da active
- 1990-08-24 IE IE309490A patent/IE66824B1/en not_active IP Right Cessation
- 1990-08-24 JP JP2221433A patent/JP2945728B2/ja not_active Expired - Fee Related
- 1990-08-24 DE DE69014480T patent/DE69014480T2/de not_active Expired - Fee Related
- 1990-08-24 AT AT90116264T patent/ATE114637T1/de not_active IP Right Cessation
- 1990-08-24 ES ES90116264T patent/ES2065446T3/es not_active Expired - Lifetime
- 1990-08-24 NZ NZ235044A patent/NZ235044A/en unknown
- 1990-08-24 PT PT95097A patent/PT95097B/pt not_active IP Right Cessation
-
1992
- 1992-03-06 US US07/846,509 patent/US5693845A/en not_active Expired - Fee Related
- 1992-10-12 PH PH45082A patent/PH30922A/en unknown
-
1993
- 1993-01-29 AU AU32145/93A patent/AU640582B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| NZ235044A (en) | 1994-05-26 |
| EP0414262B1 (de) | 1994-11-30 |
| AU3214593A (en) | 1993-03-25 |
| NO903732D0 (no) | 1990-08-24 |
| PH30922A (en) | 1997-12-23 |
| FI904164A0 (fi) | 1990-08-22 |
| ATE114637T1 (de) | 1994-12-15 |
| IE66824B1 (en) | 1996-02-07 |
| NO903732L (no) | 1991-02-26 |
| HK1000799A1 (en) | 1998-05-01 |
| DE69014480T2 (de) | 1995-04-20 |
| NO179407B (no) | 1996-06-24 |
| AU633612B2 (en) | 1993-02-04 |
| EP0414262A2 (de) | 1991-02-27 |
| MY106864A (en) | 1995-08-30 |
| JPH03236359A (ja) | 1991-10-22 |
| CA2023874A1 (en) | 1991-02-26 |
| AU6124790A (en) | 1991-02-28 |
| DE69014480D1 (de) | 1995-01-12 |
| US5693845A (en) | 1997-12-02 |
| ES2065446T3 (es) | 1995-02-16 |
| EP0414262A3 (en) | 1991-06-05 |
| JP2945728B2 (ja) | 1999-09-06 |
| DK0414262T3 (da) | 1995-05-15 |
| FI107914B (fi) | 2001-10-31 |
| IE903094A1 (en) | 1991-02-27 |
| NO179407C (no) | 1996-10-02 |
| PT95097A (pt) | 1991-04-18 |
| PT95097B (pt) | 1997-04-30 |
| AU640582B2 (en) | 1993-08-26 |
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