PH30054A - Substitution analogues of magainin peptides - Google Patents

Substitution analogues of magainin peptides

Info

Publication number
PH30054A
PH30054A PH40802A PH40802A PH30054A PH 30054 A PH30054 A PH 30054A PH 40802 A PH40802 A PH 40802A PH 40802 A PH40802 A PH 40802A PH 30054 A PH30054 A PH 30054A
Authority
PH
Philippines
Prior art keywords
magainin
magainin peptides
substitution analogues
analogues
substitution
Prior art date
Application number
PH40802A
Other languages
English (en)
Inventor
Richard A Houghten
Julio H Cuervo
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Priority to PH45486A priority Critical patent/PH30219A/en
Priority to PH45487A priority patent/PH30410A/en
Priority to PH45488A priority patent/PH30218A/en
Publication of PH30054A publication Critical patent/PH30054A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PH40802A 1989-07-07 1990-07-06 Substitution analogues of magainin peptides PH30054A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PH45486A PH30219A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of sperms
PH45487A PH30410A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of tumor
PH45488A PH30218A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of virus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37675489A 1989-07-07 1989-07-07

Publications (1)

Publication Number Publication Date
PH30054A true PH30054A (en) 1996-11-08

Family

ID=23486335

Family Applications (4)

Application Number Title Priority Date Filing Date
PH40802A PH30054A (en) 1989-07-07 1990-07-06 Substitution analogues of magainin peptides
PH45486A PH30219A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of sperms
PH45488A PH30218A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of virus
PH45487A PH30410A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of tumor

Family Applications After (3)

Application Number Title Priority Date Filing Date
PH45486A PH30219A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of sperms
PH45488A PH30218A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of virus
PH45487A PH30410A (en) 1989-07-07 1992-12-21 A process for inhibiting growth or proliferation of tumor

Country Status (16)

Country Link
EP (4) EP0761684A3 (de)
JP (1) JP2854970B2 (de)
CN (1) CN1055480C (de)
AT (1) ATE146188T1 (de)
AU (1) AU650236B2 (de)
CA (1) CA2020663C (de)
DE (1) DE69029377T2 (de)
DK (1) DK0437556T3 (de)
ES (1) ES2095255T3 (de)
IE (1) IE63842B1 (de)
IL (1) IL94939A (de)
PH (4) PH30054A (de)
PT (1) PT94625B (de)
SG (1) SG47913A1 (de)
WO (1) WO1991000869A1 (de)
ZA (1) ZA905203B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2095255T3 (es) * 1989-07-07 1997-02-16 Scripps Research Inst Analogos de sustitucion de peptidos magainina.
US5221664A (en) * 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
AU648140B2 (en) * 1991-02-01 1994-04-14 Virtual Drug Development, Inc. Reverse antimicrobial peptides and antimicrobial compositions
WO1992022317A1 (en) * 1991-06-12 1992-12-23 Magainin Pharmaceuticals, Inc. Composition and treatment with biologically active peptides having c-terminal substitutions
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
US5773413A (en) * 1993-06-04 1998-06-30 Demeter Biotechnologies, Ltd. Method of combating mammalian neoplasias, and lytic peptides therefor
CN101928340A (zh) * 2009-12-24 2010-12-29 深圳市圣西马生物技术有限公司 一组抗菌肽衍生物及其应用
CN104710523B (zh) * 2013-12-11 2017-12-29 华东理工大学 对铜绿假单胞菌具有抗菌性能的Magainin肽修饰物及其制备方法
CA2989311A1 (en) * 2015-07-02 2017-01-05 Dana-Farber Cancer Institute, Inc. Stabilized anti-microbial peptides
CN109069578A (zh) 2016-02-29 2018-12-21 达纳-法伯癌症研究所股份有限公司 用于治疗感染的钉合的细胞内靶向抗微生物肽
JP7305614B2 (ja) * 2017-07-19 2023-07-10 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド 抗生物質耐性細菌感染症の処置のための安定化抗菌ペプチド
CN111892646B (zh) * 2020-08-13 2023-05-02 中国人民解放军军事科学院军事医学研究院 抗菌肽衍生物及其在制备抗细菌感染药物中的应用
CN112625092B (zh) * 2021-01-13 2023-03-28 兰州大学 一种基于polybia-MPI的抗菌多肽化合物及其合成与应用
CN114634553B (zh) * 2022-04-27 2024-03-08 贵州医科大学 阳离子肽c9及其应用
CN120081951B (zh) * 2025-03-06 2025-09-30 辽宁波尔莱特农牧实业集团有限公司 一种抗菌肽Magainin 2-hEGF融合蛋白及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810777A (en) * 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds
EP0362209B1 (de) * 1987-03-04 1994-06-08 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Neue synthetische bioaktive verbindungen und verfahren zur herstellung bioaktiver wirkungen
ES2095255T3 (es) * 1989-07-07 1997-02-16 Scripps Research Inst Analogos de sustitucion de peptidos magainina.

Also Published As

Publication number Publication date
EP0437556B1 (de) 1996-12-11
WO1991000869A1 (en) 1991-01-24
CN1049166A (zh) 1991-02-13
DE69029377T2 (de) 1997-06-19
SG47913A1 (en) 1998-04-17
CA2020663A1 (en) 1991-01-08
DK0437556T3 (da) 1996-12-30
PH30219A (en) 1997-02-05
PT94625A (pt) 1991-03-20
EP0761684A3 (de) 1997-07-02
JPH04506801A (ja) 1992-11-26
AU650236B2 (en) 1994-06-16
EP0751149A3 (de) 1997-07-02
IE63842B1 (en) 1995-06-14
ES2095255T3 (es) 1997-02-16
EP0751148A2 (de) 1997-01-02
EP0751149A2 (de) 1997-01-02
IL94939A0 (en) 1991-06-10
PT94625B (pt) 1997-03-31
CA2020663C (en) 1999-12-07
PH30218A (en) 1997-02-05
ATE146188T1 (de) 1996-12-15
EP0761684A2 (de) 1997-03-12
EP0751148A3 (de) 1997-07-02
AU5945490A (en) 1991-02-06
EP0437556A1 (de) 1991-07-24
IL94939A (en) 1996-12-05
PH30410A (en) 1997-05-09
CN1055480C (zh) 2000-08-16
EP0437556A4 (en) 1992-05-20
JP2854970B2 (ja) 1999-02-10
ZA905203B (en) 1991-05-29
IE902476A1 (en) 1991-02-13
DE69029377D1 (de) 1997-01-23

Similar Documents

Publication Publication Date Title
IL94939A0 (en) Substitution analogues of magainin peptides
AU6286986A (en) Peptide analogues of mammalian insulin-like growth factor-1
MY102058A (en) Enzyme inhibitors
ATE22449T1 (de) Dynorphinamidanaloge.
WO1990012874A3 (en) Cysteine added variants of polypeptides and chemical modifications thereof
ATE178908T1 (de) Lys(b28) insuline. analoge des menschlichen insulins
CA2265900A1 (en) Improved solid-phase peptide synthesis and agent for use in such synthesis
CA2004991A1 (en) Deletion analogues of magainin peptides
PL325905A1 (en) Analogues of parathyroid hormone
KR100295606B1 (de)
DE3261304D1 (en) Retro-inverso analogues of c-terminal penta and hexapeptides of substance p.
MX9702665A (es) Analogos del factor de crecimiento de queratinocitos.
MX167236B (es) Peptidos sinteticos de timosina -1 y metodo para su obtencion
EP0297456A3 (de) Immunsuppressive Peptide
EP0258203A3 (en) Novel substrate peptides
JPS6470500A (en) Somatostatin analogue compound for treatment
NO901558L (no) Vasoaktive peptider.