PL1631569T3 - Pochodne chinuklidyny wiążące się z receptorami muskarynowymi M3 - Google Patents

Pochodne chinuklidyny wiążące się z receptorami muskarynowymi M3

Info

Publication number
PL1631569T3
PL1631569T3 PL04730519T PL04730519T PL1631569T3 PL 1631569 T3 PL1631569 T3 PL 1631569T3 PL 04730519 T PL04730519 T PL 04730519T PL 04730519 T PL04730519 T PL 04730519T PL 1631569 T3 PL1631569 T3 PL 1631569T3
Authority
PL
Poland
Prior art keywords
mucarinic
receptors
quinuclidine derivatives
derivatives binding
binding
Prior art date
Application number
PL04730519T
Other languages
English (en)
Inventor
Stephen Paul Collingwood
Brian Cox
Urs Baettig
Gurdip Bhalay
Nicholas James Devereux
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33420896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1631569(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0324887A external-priority patent/GB0324887D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL1631569T3 publication Critical patent/PL1631569T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL04730519T 2003-05-02 2004-04-30 Pochodne chinuklidyny wiążące się z receptorami muskarynowymi M3 PL1631569T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0310232 2003-05-02
GB0324887A GB0324887D0 (en) 2003-10-24 2003-10-24 Organic compounds
PCT/EP2004/004605 WO2004096800A2 (en) 2003-05-02 2004-04-30 Quinuclidine derivatives binding to mucarinic m3 receptors
EP04730519A EP1631569B1 (en) 2003-05-02 2004-04-30 Quinuclidine derivatives binding to mucarinic m3 receptors

Publications (1)

Publication Number Publication Date
PL1631569T3 true PL1631569T3 (pl) 2010-02-26

Family

ID=33420896

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04730519T PL1631569T3 (pl) 2003-05-02 2004-04-30 Pochodne chinuklidyny wiążące się z receptorami muskarynowymi M3

Country Status (31)

Country Link
US (2) US20070060563A1 (pl)
EP (1) EP1631569B1 (pl)
JP (1) JP4416786B2 (pl)
KR (1) KR100896544B1 (pl)
AR (1) AR044134A1 (pl)
AT (1) ATE440840T1 (pl)
AU (1) AU2004234069B2 (pl)
BR (1) BRPI0410238A (pl)
CA (1) CA2523436C (pl)
CL (1) CL2004000918A1 (pl)
CO (1) CO5700782A2 (pl)
CY (1) CY1109655T1 (pl)
DE (1) DE602004022805D1 (pl)
DK (1) DK1631569T3 (pl)
EC (1) ECSP056134A (pl)
ES (1) ES2331185T3 (pl)
HR (1) HRP20050933A2 (pl)
IL (1) IL171591A (pl)
IS (1) IS2746B (pl)
MA (1) MA27775A1 (pl)
MX (1) MXPA05011739A (pl)
MY (1) MY142652A (pl)
NO (1) NO20055688L (pl)
NZ (1) NZ542995A (pl)
PE (1) PE20050465A1 (pl)
PL (1) PL1631569T3 (pl)
PT (1) PT1631569E (pl)
RU (1) RU2363700C2 (pl)
SI (1) SI1631569T1 (pl)
TW (1) TWI340139B (pl)
WO (1) WO2004096800A2 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0428416D0 (en) 2004-12-24 2005-02-02 Novartis Ag Organic compounds
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide
EP1894568A1 (en) * 2006-08-31 2008-03-05 Novartis AG Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
TW200825084A (en) * 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
KR20090094460A (ko) * 2006-12-19 2009-09-07 아스트라제네카 아베 무스카린 수용체 길항제로서 퀴누클리디놀 유도체
EP1950196A1 (de) * 2007-01-29 2008-07-30 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Ammoniumhexafluorophosphaten
MX2010002576A (es) * 2007-09-07 2010-04-01 Theravance Inc Compuestos que contienen guanidina, utiles como antagonistas de los receptores muscarinicos.
EP2222637A1 (en) * 2007-12-14 2010-09-01 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
JP5584138B2 (ja) 2008-01-11 2014-09-03 ノバルティス アーゲー キナーゼ阻害剤としてのピリミジン類
US8329729B2 (en) * 2008-05-13 2012-12-11 Astrazeneca Ab Quinuclidine derivatives as muscarinic M3 receptor antagonists
EP2315589A4 (en) * 2008-05-13 2013-09-11 Astrazeneca Ab PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A beta2-ADRENOCEPTOR AGONIST
GB0808709D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New combination 295
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
WO2009153536A1 (en) * 2008-06-17 2009-12-23 Argenta Discovery Limited 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
CA2803459A1 (en) * 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Alkaloid aminoester derivatives and medicinal compositions thereof
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
BR112013021638A2 (pt) 2011-02-25 2016-08-02 Irm Llc "compostos inibidores de trk, seu uso e composições que os compreendem"
JP2011195593A (ja) * 2011-06-30 2011-10-06 Astrazeneca Ab ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
KR20140105746A (ko) * 2011-12-30 2014-09-02 키에시 파르마슈티시 엣스. 피. 에이. 항무스카린제로서 1-아자헤테로시클릴아세트산의 퀴누클리딘 에스터, 이들의 제조 방법 및 이들의 의약 조성물
CN104470515B (zh) 2012-05-03 2016-12-07 圣路易斯药学院 用于增加神经营养肽的组合物和方法
TWI647227B (zh) * 2013-02-28 2019-01-11 日商安斯泰來製藥股份有限公司 ２－醯胺噻唑衍生物或其鹽
CZ306791B6 (cs) 2013-10-29 2017-07-12 Zentiva, K.S. Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě
PT108370B (pt) * 2015-03-30 2018-10-25 Hovione Farm S A Processo de preparação de brometo de aclidínio
PT3111978T (pt) 2015-07-03 2021-12-06 Novartis Ag Inalador adaptado para ler informação armazenada num meio de armazenamento de dados de um recipiente

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
DK534178A (da) * 1977-12-16 1979-06-17 Interx Research Corp Anticholinerge midler med sektrtionshaemmende virkning
IT1230881B (it) * 1989-06-20 1991-11-08 Angeli Inst Spa Derivati del r(-) 3-chinuclidinolo
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
EP1302458A4 (en) * 2000-07-11 2005-10-19 Banyu Pharma Co Ltd ESTERDERIVATE
SI1353919T1 (sl) * 2000-12-28 2006-12-31 Almirall Prodesfarma Ag Novi derivati kinuklidina in medicinske zmesi, kijih vsebujejo.
CA2470956C (en) * 2001-12-20 2011-08-02 Laboratorios S.A.L.V.A.T., S.A. 1-alkyl-1-azoniabicyclo[2.2.2]octane carbamate derivatives and their use as muscarinic receptor antagonists
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide

Also Published As

Publication number Publication date
AR044134A1 (es) 2005-08-24
MA27775A1 (fr) 2006-02-01
CL2004000918A1 (es) 2005-02-11
HRP20050933A2 (en) 2006-12-31
TW200505920A (en) 2005-02-16
SI1631569T1 (sl) 2010-01-29
JP2006525267A (ja) 2006-11-09
NZ542995A (en) 2009-02-28
US20100041887A1 (en) 2010-02-18
BRPI0410238A (pt) 2006-05-16
CO5700782A2 (es) 2006-11-30
DE602004022805D1 (de) 2009-10-08
DK1631569T3 (da) 2009-11-23
MY142652A (en) 2010-12-15
AU2004234069B2 (en) 2008-02-21
IS2746B (is) 2011-08-15
PE20050465A1 (es) 2005-07-18
EP1631569B1 (en) 2009-08-26
IS8158A (is) 2005-11-30
EP1631569A2 (en) 2006-03-08
RU2005137360A (ru) 2006-07-27
ES2331185T3 (es) 2009-12-23
NO20055688L (no) 2006-01-09
CY1109655T1 (el) 2014-08-13
PT1631569E (pt) 2009-11-26
IL171591A (en) 2010-11-30
KR20060015572A (ko) 2006-02-17
CA2523436C (en) 2011-11-01
ATE440840T1 (de) 2009-09-15
US8168654B2 (en) 2012-05-01
AU2004234069A1 (en) 2004-11-11
MXPA05011739A (es) 2006-01-26
KR100896544B1 (ko) 2009-05-07
JP4416786B2 (ja) 2010-02-17
HK1087704A1 (en) 2006-10-20
WO2004096800A2 (en) 2004-11-11
RU2363700C2 (ru) 2009-08-10
CA2523436A1 (en) 2004-11-11
US20070060563A1 (en) 2007-03-15
ECSP056134A (es) 2006-04-19
TWI340139B (en) 2011-04-11
WO2004096800A3 (en) 2005-01-06
NO20055688D0 (no) 2005-12-01

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