TWI340139B - Organic compounds - Google Patents

Organic compounds

Info

Publication number: TWI340139B
Authority: TW; Taiwan
Prior art keywords: organic compounds; compounds; organic
Prior art date: 2003-05-02

Application number

TW093112339A

Other languages

English (en)

Other versions

TW200505920A (en

Inventor

Stephen Paul Collingwood

Brian Cox

Urs Baettig

Gurdip Bhalay

Nicholas James Devereux

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-02

Filing date

2004-04-30

Publication date

2011-04-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33420896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI340139(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-10-24 Priority claimed from GB0324887A external-priority patent/GB0324887D0/en

2004-04-30 Application filed by Novartis Ag filed Critical Novartis Ag

2005-02-16 Publication of TW200505920A publication Critical patent/TW200505920A/zh

2011-04-11 Application granted granted Critical

2011-04-11 Publication of TWI340139B publication Critical patent/TWI340139B/zh

Links

150000002894 organic compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

TW093112339A 2003-05-02 2004-04-30 Organic compounds TWI340139B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0310232		2003-05-02
GB0324887A GB0324887D0 (en)	2003-10-24	2003-10-24	Organic compounds

Publications (2)

Publication Number	Publication Date
TW200505920A TW200505920A (en)	2005-02-16
TWI340139B true TWI340139B (en)	2011-04-11

Family

ID=33420896

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW093112339A TWI340139B (en)	2003-05-02	2004-04-30	Organic compounds

Country Status (31)

Country	Link
US (2)	US20070060563A1 (zh)
EP (1)	EP1631569B1 (zh)
JP (1)	JP4416786B2 (zh)
KR (1)	KR100896544B1 (zh)
AR (1)	AR044134A1 (zh)
AT (1)	ATE440840T1 (zh)
AU (1)	AU2004234069B2 (zh)
BR (1)	BRPI0410238A (zh)
CA (1)	CA2523436C (zh)
CL (1)	CL2004000918A1 (zh)
CO (1)	CO5700782A2 (zh)
CY (1)	CY1109655T1 (zh)
DE (1)	DE602004022805D1 (zh)
DK (1)	DK1631569T3 (zh)
EC (1)	ECSP056134A (zh)
ES (1)	ES2331185T3 (zh)
HR (1)	HRP20050933A2 (zh)
IL (1)	IL171591A (zh)
IS (1)	IS2746B (zh)
MA (1)	MA27775A1 (zh)
MX (1)	MXPA05011739A (zh)
MY (1)	MY142652A (zh)
NO (1)	NO20055688L (zh)
NZ (1)	NZ542995A (zh)
PE (1)	PE20050465A1 (zh)
PL (1)	PL1631569T3 (zh)
PT (1)	PT1631569E (zh)
RU (1)	RU2363700C2 (zh)
SI (1)	SI1631569T1 (zh)
TW (1)	TWI340139B (zh)
WO (1)	WO2004096800A2 (zh)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2239546B1 (es) *	2004-03-15	2006-12-01	Almirall Prodesfarma, S.A.	Nuevos esteres de quinuclidina cuaternizados.
GB0410712D0 (en)	2004-05-13	2004-06-16	Novartis Ag	Organic compounds
GB0424284D0 (en)	2004-11-02	2004-12-01	Novartis Ag	Organic compounds
GB0428416D0 (en) *	2004-12-24	2005-02-02	Novartis Ag	Organic compounds
GB0601951D0 (en)	2006-01-31	2006-03-15	Novartis Ag	Organic compounds
EP1900737A1 (en) *	2006-08-31	2008-03-19	Novartis AG	Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide
EP1894568A1 (en) *	2006-08-31	2008-03-05	Novartis AG	Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
TW200825084A (en)	2006-11-14	2008-06-16	Astrazeneca Ab	New compounds 521
WO2008075005A1 (en) *	2006-12-19	2008-06-26	Astrazeneca Ab	Quinuclidinol derivatives as muscarinic receptor antagonists
EP1950196A1 (de) *	2007-01-29	2008-07-30	Boehringer Ingelheim Pharma GmbH & Co. KG	Verfahren zur Herstellung von Ammoniumhexafluorophosphaten
JP5656288B2 (ja)	2007-09-07	2015-01-21	セラヴァンスバイオファーマアール＆ディーアイピー，エルエルシー	ムスカリン受容体アンタゴニストとして有用なグアジニン含有化合物
US8017617B2 (en) *	2007-12-14	2011-09-13	Theravance, Inc.	Amidine-containing compounds useful as muscarinic receptor antagonists
EP2231642B1 (en)	2008-01-11	2013-10-23	Novartis AG	Pyrimidines as kinase inhibitors
GB0808709D0 (en) *	2008-05-13	2008-06-18	Astrazeneca Ab	New combination 295
NZ589091A (en) *	2008-05-13	2011-07-29	Astrazeneca Ab	Quinuclidine derivatives as muscarinic m3 receptor antagonists
CN102908624A (zh) *	2008-05-13	2013-02-06	阿斯利康(瑞典)有限公司	包含毒蕈碱性受体拮抗剂和β2-肾上腺素受体激动剂的药物产品
US20090326004A1 (en)	2008-06-03	2009-12-31	Ranbaxy Laboratories Limited	Muscarinic receptor antagonists
WO2009153536A1 (en) *	2008-06-17	2009-12-23	Argenta Discovery Limited	1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
GB0811100D0 (en) *	2008-06-17	2008-07-23	Astrazeneca Ab	New combination
CN102947300B (zh) *	2010-06-22	2016-09-21	奇斯药制品公司	生物碱氨基酯衍生物及其药物组合物
WO2012034095A1 (en)	2010-09-09	2012-03-15	Irm Llc	Compounds and compositions as trk inhibitors
US8637516B2 (en)	2010-09-09	2014-01-28	Irm Llc	Compounds and compositions as TRK inhibitors
AU2012220572A1 (en)	2011-02-25	2013-08-29	Irm Llc	Compounds and compositions as trk inhibitors
JP2011195593A (ja) *	2011-06-30	2011-10-06	Astrazeneca Ab	ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
WO2013098145A1 (en) *	2011-12-30	2013-07-04	Chiesi Farmaceutici S.P.A.	Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof
CN104470515B (zh)	2012-05-03	2016-12-07	圣路易斯药学院	用于增加神经营养肽的组合物和方法
TWI647227B (zh) *	2013-02-28	2019-01-11	日商安斯泰來製藥股份有限公司	２－醯胺噻唑衍生物或其鹽
CZ306791B6 (cs)	2013-10-29	2017-07-12	Zentiva, K.S.	Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě
PT108370B (pt) *	2015-03-30	2018-10-25	Hovione Farm S A	Processo de preparação de brometo de aclidínio
PT3111978T (pt)	2015-07-03	2021-12-06	Novartis Ag	Inalador adaptado para ler informação armazenada num meio de armazenamento de dados de um recipiente

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1219606A (en) *	1968-07-15	1971-01-20	Rech S Et D Applic Scient Soge	Quinuclidinol derivatives and preparation thereof
DK534178A (da) *	1977-12-16	1979-06-17	Interx Research Corp	Anticholinerge midler med sektrtionshaemmende virkning
IT1230881B (it) *	1989-06-20	1991-11-08	Angeli Inst Spa	Derivati del r(-) 3-chinuclidinolo
ES2165768B1 (es) *	1999-07-14	2003-04-01	Almirall Prodesfarma Sa	Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
CA2415468A1 (en) *	2000-07-11	2003-01-10	Yoshio Ogino	Ester derivatives
CN1250545C (zh) *	2000-12-28	2006-04-12	阿尔米雷尔普罗迪斯制药有限公司	新的奎宁环衍生物类及含有这类衍生物的药物组合物
JP4505227B2 (ja) *	2001-12-20	2010-07-21	キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ	１−アルキル−１−アゾニアビシクロ［２．２．２］オクタンカルバメート誘導体およびムスカリンレセプターアンタゴニストとしてのそれらの使用
GB0424284D0 (en) *	2004-11-02	2004-12-01	Novartis Ag	Organic compounds
EP1900737A1 (en) *	2006-08-31	2008-03-19	Novartis AG	Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide

2004
- 2004-04-29 AR ARP040101468A patent/AR044134A1/es not_active Application Discontinuation
- 2004-04-30 PL PL04730519T patent/PL1631569T3/pl unknown
- 2004-04-30 TW TW093112339A patent/TWI340139B/zh not_active IP Right Cessation
- 2004-04-30 US US10/554,558 patent/US20070060563A1/en not_active Abandoned
- 2004-04-30 HR HR20050933A patent/HRP20050933A2/xx not_active Application Discontinuation
- 2004-04-30 KR KR1020057020776A patent/KR100896544B1/ko not_active Expired - Fee Related
- 2004-04-30 AU AU2004234069A patent/AU2004234069B2/en not_active Ceased
- 2004-04-30 ES ES04730519T patent/ES2331185T3/es not_active Expired - Lifetime
- 2004-04-30 EP EP04730519A patent/EP1631569B1/en not_active Expired - Lifetime
- 2004-04-30 MX MXPA05011739A patent/MXPA05011739A/es active IP Right Grant
- 2004-04-30 CL CL200400918A patent/CL2004000918A1/es unknown
- 2004-04-30 BR BRPI0410238-0A patent/BRPI0410238A/pt not_active IP Right Cessation
- 2004-04-30 DE DE602004022805T patent/DE602004022805D1/de not_active Expired - Lifetime
- 2004-04-30 CA CA2523436A patent/CA2523436C/en not_active Expired - Fee Related
- 2004-04-30 NZ NZ542995A patent/NZ542995A/en not_active IP Right Cessation
- 2004-04-30 SI SI200431277T patent/SI1631569T1/sl unknown
- 2004-04-30 DK DK04730519T patent/DK1631569T3/da active
- 2004-04-30 AT AT04730519T patent/ATE440840T1/de active
- 2004-04-30 MY MYPI20041637A patent/MY142652A/en unknown
- 2004-04-30 PT PT04730519T patent/PT1631569E/pt unknown
- 2004-04-30 RU RU2005137360/04A patent/RU2363700C2/ru not_active IP Right Cessation
- 2004-04-30 PE PE2004000435A patent/PE20050465A1/es not_active Application Discontinuation
- 2004-04-30 JP JP2006505341A patent/JP4416786B2/ja not_active Expired - Fee Related
- 2004-04-30 WO PCT/EP2004/004605 patent/WO2004096800A2/en not_active Ceased
2005
- 2005-10-27 IL IL171591A patent/IL171591A/en not_active IP Right Cessation
- 2005-11-01 EC EC2005006134A patent/ECSP056134A/es unknown
- 2005-11-03 CO CO05112195A patent/CO5700782A2/es not_active Application Discontinuation
- 2005-11-08 MA MA28583A patent/MA27775A1/fr unknown
- 2005-11-30 IS IS8158A patent/IS2746B/is unknown
- 2005-12-01 NO NO20055688A patent/NO20055688L/no not_active Application Discontinuation
2009
- 2009-10-20 US US12/582,291 patent/US8168654B2/en not_active Expired - Fee Related
- 2009-11-25 CY CY20091101230T patent/CY1109655T1/el unknown

Also Published As

Publication number	Publication date
KR20060015572A (ko)	2006-02-17
PL1631569T3 (pl)	2010-02-26
DE602004022805D1 (de)	2009-10-08
PE20050465A1 (es)	2005-07-18
DK1631569T3 (da)	2009-11-23
RU2363700C2 (ru)	2009-08-10
NO20055688L (no)	2006-01-09
CL2004000918A1 (es)	2005-02-11
MA27775A1 (fr)	2006-02-01
HK1087704A1 (zh)	2006-10-20
US20100041887A1 (en)	2010-02-18
WO2004096800A3 (en)	2005-01-06
IS8158A (is)	2005-11-30
JP2006525267A (ja)	2006-11-09
CO5700782A2 (es)	2006-11-30
CY1109655T1 (el)	2014-08-13
MY142652A (en)	2010-12-15
JP4416786B2 (ja)	2010-02-17
SI1631569T1 (sl)	2010-01-29
PT1631569E (pt)	2009-11-26
MXPA05011739A (es)	2006-01-26
TW200505920A (en)	2005-02-16
US8168654B2 (en)	2012-05-01
ES2331185T3 (es)	2009-12-23
BRPI0410238A (pt)	2006-05-16
RU2005137360A (ru)	2006-07-27
IS2746B (is)	2011-08-15
AU2004234069A1 (en)	2004-11-11
EP1631569A2 (en)	2006-03-08
NZ542995A (en)	2009-02-28
AU2004234069B2 (en)	2008-02-21
NO20055688D0 (no)	2005-12-01
KR100896544B1 (ko)	2009-05-07
CA2523436C (en)	2011-11-01
AR044134A1 (es)	2005-08-24
IL171591A (en)	2010-11-30
US20070060563A1 (en)	2007-03-15
ATE440840T1 (de)	2009-09-15
CA2523436A1 (en)	2004-11-11
ECSP056134A (es)	2006-04-19
HRP20050933A2 (en)	2006-12-31
WO2004096800A2 (en)	2004-11-11
EP1631569B1 (en)	2009-08-26

Legal Events

Date	Code	Title	Description
2013-01-11	MM4A	Annulment or lapse of patent due to non-payment of fees

Publication	Publication Date	Title
TWI347941B (en)	2011-09-01	Organic compounds
GB0402677D0 (en)	2004-03-10	Organic compounds
IL175435A0 (en)	2006-09-05	Organic compounds
GB0303503D0 (en)	2003-03-19	Organic compounds
GB0325603D0 (en)	2003-12-10	Organic compounds
GB0326601D0 (en)	2003-12-17	Organic compounds
GB0307553D0 (en)	2003-05-07	Organic compounds
GB0302876D0 (en)	2003-03-12	Organic compounds
GB0326602D0 (en)	2003-12-17	Organic compounds
GB0300095D0 (en)	2003-02-05	Organic compounds
GB0302748D0 (en)	2003-03-12	Organic compounds
GB0301938D0 (en)	2003-02-26	Organic compounds
GB0301471D0 (en)	2003-02-19	Organic compounds
GB0312086D0 (en)	2003-07-02	Organic compounds
GB0311971D0 (en)	2003-06-25	Organic compounds
GB0303506D0 (en)	2003-03-19	Organic compounds
GB0306071D0 (en)	2003-04-23	Organic compounds
GB0302991D0 (en)	2003-03-12	Organic compounds
GB0301470D0 (en)	2003-02-19	Organic compounds
GB0302874D0 (en)	2003-03-12	Organic compounds
GB0302433D0 (en)	2003-03-05	Organic compounds
GB0300590D0 (en)	2003-02-12	Organic compounds
GB0300021D0 (en)	2003-02-05	Organic compounds
GB0303321D0 (en)	2003-03-19	Organic compounds
GB0308009D0 (en)	2003-05-14	Organic compounds