PL1651249T3 - Zastosowanie kalcytoniny w zapaleniu kości i stawów - Google Patents

Zastosowanie kalcytoniny w zapaleniu kości i stawów

Info

Publication number: PL1651249T3
Authority: PL; Poland
Prior art keywords: calcitonin; osteoarthritis
Prior art date: 2003-07-23

Application number

PL04741224T

Other languages

English (en)

Inventor

Moise Azria

Claus Christiansen

Simon David Bateman

Shoufeng Li

Original Assignee

Novartis Ag

Nordic Bioscience As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-23

Filing date

2004-07-22

Publication date

2013-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34135096&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1651249(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-07-22 Application filed by Novartis Ag, Nordic Bioscience As filed Critical Novartis Ag

2013-04-30 Publication of PL1651249T3 publication Critical patent/PL1651249T3/pl

Links

102000055006 Calcitonin Human genes 0.000 title 1
108060001064 Calcitonin Proteins 0.000 title 1
BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 title 1
229960004015 calcitonin Drugs 0.000 title 1
201000008482 osteoarthritis Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Physical Education & Sports Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Otolaryngology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Hospice & Palliative Care (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL04741224T 2003-07-23 2004-07-22 Zastosowanie kalcytoniny w zapaleniu kości i stawów PL1651249T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US48940003P	2003-07-23	2003-07-23
PCT/EP2004/008210 WO2005014031A1 (en)	2003-07-23	2004-07-22	Use of calcitonin in osteoarthritis
EP04741224A EP1651249B1 (en)	2003-07-23	2004-07-22	Use of calcitonin in osteoarthritis

Publications (1)

Publication Number	Publication Date
PL1651249T3 true PL1651249T3 (pl)	2013-04-30

Family

ID=34135096

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL10177751T PL2316473T3 (pl)	2003-07-23	2004-07-22	Zastosowanie kalcytoniny w chorobie zwyrodnieniowej stawów
PL04741224T PL1651249T3 (pl)	2003-07-23	2004-07-22	Zastosowanie kalcytoniny w zapaleniu kości i stawów

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL10177751T PL2316473T3 (pl)	2003-07-23	2004-07-22	Zastosowanie kalcytoniny w chorobie zwyrodnieniowej stawów

Country Status (22)

Country	Link
US (3)	US7749954B2 (pl)
EP (2)	EP2316473B1 (pl)
JP (2)	JP4716987B2 (pl)
KR (1)	KR101070036B1 (pl)
CN (1)	CN1856321B (pl)
AU (2)	AU2004262906B2 (pl)
BR (1)	BRPI0412265A (pl)
CA (1)	CA2532565C (pl)
ES (2)	ES2436152T3 (pl)
IL (2)	IL173002A (pl)
IS (1)	IS8316A (pl)
MA (1)	MA27929A1 (pl)
MX (1)	MXPA06000807A (pl)
NO (1)	NO330867B1 (pl)
NZ (1)	NZ544645A (pl)
PL (2)	PL2316473T3 (pl)
PT (2)	PT2316473E (pl)
RU (1)	RU2368390C2 (pl)
TN (1)	TNSN06022A1 (pl)
TW (1)	TWI343816B (pl)
WO (1)	WO2005014031A1 (pl)
ZA (1)	ZA200600373B (pl)

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MXPA04005080A (es) *	2004-05-27	2005-11-30	Aspid S A De C V	Una composicion moduladora de la inflamacion articular cronica a base de colagena-polivinilpirrolidona.
PE20070548A1 (es)	2005-09-19	2007-07-12	Emisphere Tech Inc	Formas cristalinas de la sal de di-sodio del acido n-(5-clorosaliciloil)-8-aminocaprilico
GB0522566D0 (en) *	2005-11-04	2005-12-14	Novartis Ag	Organic compounds
AU2006318815B2 (en)	2005-11-17	2010-08-19	Novartis Ag	Pharmaceutical composition
EP2059260B1 (en)	2006-08-31	2013-06-19	Novartis AG	Pharmaceutical compositions comprising hGH for oral delivery
WO2008109385A2 (en) *	2007-03-02	2008-09-12	Novartis Ag	Oral administration of a calcitonin
WO2009019307A2 (en) *	2007-08-09	2009-02-12	Novartis Ag	Oral calcitonin compositions and applications thereof
US8022048B2 (en)	2007-11-02	2011-09-20	Emisphere Technologies, Inc.	Method of treating vitamin B12 deficiency
CN102123697B (zh)	2008-08-18	2015-06-10	安特拉贝欧有限公司	用于口服给予蛋白质的方法和组合物
EP2405934B1 (en)	2009-03-12	2014-03-26	Nordic Bioscience A/S	Treatment of diabetes and metabolic syndrome
ES2583259T3 (es) *	2009-12-01	2016-09-20	Novo Nordisk A/S	Nuevas liasas alfa-amidantes de peptidil alfa-hidroxiglicina
WO2012040364A1 (en) *	2010-09-21	2012-03-29	Unigene Laboratories Inc.	Calcitonin products and therapies for treating inflammatory or degenerative diseases
CA2854175A1 (en)	2011-11-02	2013-05-10	Keybioscience Ag	Peptide analogs for treating diseases and disorders
SI3095484T1 (en)	2011-11-02	2018-08-31	Keybioscience Ag	Calcitonin mimetics for the treatment of diseases and disorders
AU2013234096B2 (en) *	2012-03-16	2018-08-09	Fertility Innovations Limited	Processing of sperm cells
BR112016010643A2 (pt)	2013-11-14	2017-12-05	Keybioscience Ag	peptídeo
CN104095828A (zh) *	2014-07-29	2014-10-15	中国药科大学	一种降钙素口服肠溶组合物及其制备方法
GB201500263D0 (en)	2015-01-08	2015-02-25	Keybioscience Ag	Calcitonin analogues for treating diseases and disorders
US9849125B1 (en)	2015-11-03	2017-12-26	Banner Lifie Sciences LLC	Anti-overingestion dosage forms
GB201704429D0 (en)	2017-03-21	2017-05-03	Keybioscience Ag	Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en)	2017-05-18	2017-07-05	Keybioscience Ag	Dual amylin and calcitonin receptor agonists for treating diseases and disorders
US10335375B2 (en)	2017-05-30	2019-07-02	Patheon Softgels, Inc.	Anti-overingestion abuse deterrent compositions
KR20190036903A (ko)	2017-09-28	2019-04-05	(주)휴럼	리트세노라이드를 유효성분으로 하는 염증과 골관절염에 대한 예방 및 치료용 약학 조성물
US11274158B2 (en) *	2018-01-30	2022-03-15	Flagship Pioneering Innovations V, Inc.	Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators
CN108586601B (zh) *	2018-05-14	2021-07-27	四川大学	一种骨靶向性鲑鱼降钙素及其制备方法
GB201813678D0 (en)	2018-08-22	2018-10-03	Keybioscience Ag	Acylated calcitonin mimetics
GB201813677D0 (en)	2018-08-22	2018-10-03	Keybioscience Ag	Calcitonin mimetics for treating diseases and disorders
JP2023515886A (ja)	2020-03-02	2023-04-14	マジックリープ，インコーポレイテッド	没入型のオーディオプラットフォーム

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TW448172B (en) *	1996-03-08	2001-08-01	Pharmacia & Upjohn Co Llc	Novel hydroxamic acid derivatives useful for the treatment of diseases related to connective tissue degradation
US5912014A (en)	1996-03-15	1999-06-15	Unigene Laboratories, Inc.	Oral salmon calcitonin pharmaceutical products
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US5773647A (en)	1997-02-07	1998-06-30	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
NZ534409A (en)	1999-04-05	2006-03-31	Emisphere Tech Inc	Disodium salts, monohydrates, and ethanol solvates for delivering active agents
US6309633B1 (en)	1999-06-19	2001-10-30	Nobex Corporation	Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
US6380405B1 (en)	1999-09-13	2002-04-30	Nobex Corporation	Taxane prodrugs
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US20020012459A1 (en)	2000-06-22	2002-01-31	Chips Brain Co. Ltd.	Method and apparatus for detecting stereo disparity in sequential parallel processing mode
EP1313699B1 (en)	2000-08-29	2010-03-10	Biocon Limited	5-asa derivatives having anti-inflammatory and antibiotic activity and methods of treating diseases therewith
US20040009980A1 (en)	2000-10-25	2004-01-15	Pradip Bhatnagar	Calcilytic compounds
US7049283B2 (en) *	2000-12-06	2006-05-23	Novartis Ag	Pharmaceutical compositions for the oral delivery of pharmacologically active agents
US6479692B1 (en)	2001-05-02	2002-11-12	Nobex Corporation	Methods of synthesizing acylanilides including bicalutamide and derivatives thereof
DE60233803D1 (de)	2001-08-17	2009-11-05	Novartis Ag	5-cnac zur oralen verabreichung von parathormonfragmenten

2004
- 2004-07-22 PT PT101777514T patent/PT2316473E/pt unknown
- 2004-07-22 WO PCT/EP2004/008210 patent/WO2005014031A1/en not_active Ceased
- 2004-07-22 ES ES10177751T patent/ES2436152T3/es not_active Expired - Lifetime
- 2004-07-22 NZ NZ544645A patent/NZ544645A/xx not_active IP Right Cessation
- 2004-07-22 EP EP10177751.4A patent/EP2316473B1/en not_active Expired - Lifetime
- 2004-07-22 ES ES04741224T patent/ES2398237T3/es not_active Expired - Lifetime
- 2004-07-22 TW TW093121910A patent/TWI343816B/zh not_active IP Right Cessation
- 2004-07-22 PT PT47412242T patent/PT1651249E/pt unknown
- 2004-07-22 MX MXPA06000807A patent/MXPA06000807A/es active IP Right Grant
- 2004-07-22 PL PL10177751T patent/PL2316473T3/pl unknown
- 2004-07-22 AU AU2004262906A patent/AU2004262906B2/en not_active Ceased
- 2004-07-22 CN CN2004800210875A patent/CN1856321B/zh not_active Expired - Fee Related
- 2004-07-22 PL PL04741224T patent/PL1651249T3/pl unknown
- 2004-07-22 KR KR1020067001391A patent/KR101070036B1/ko not_active Expired - Fee Related
- 2004-07-22 BR BRPI0412265-8A patent/BRPI0412265A/pt not_active Application Discontinuation
- 2004-07-22 EP EP04741224A patent/EP1651249B1/en not_active Revoked
- 2004-07-22 JP JP2006520797A patent/JP4716987B2/ja not_active Expired - Fee Related
- 2004-07-22 RU RU2006105479/14A patent/RU2368390C2/ru not_active IP Right Cessation
- 2004-07-22 US US10/565,455 patent/US7749954B2/en not_active Expired - Fee Related
- 2004-07-22 CA CA2532565A patent/CA2532565C/en not_active Expired - Fee Related
2006
- 2006-01-05 IL IL173002A patent/IL173002A/en not_active IP Right Cessation
- 2006-01-13 ZA ZA200600373A patent/ZA200600373B/en unknown
- 2006-01-20 TN TNP2006000022A patent/TNSN06022A1/en unknown
- 2006-01-23 MA MA28746A patent/MA27929A1/fr unknown
- 2006-02-21 IS IS8316A patent/IS8316A/is unknown
- 2006-02-23 NO NO20060890A patent/NO330867B1/no not_active IP Right Cessation
2008
- 2008-06-30 AU AU2008202879A patent/AU2008202879B2/en not_active Ceased
2010
- 2010-06-21 US US12/819,583 patent/US8765675B2/en not_active Expired - Fee Related
2011
- 2011-02-22 JP JP2011035273A patent/JP2011121987A/ja active Pending
2013
- 2013-08-15 IL IL227988A patent/IL227988A/en not_active IP Right Cessation
2014
- 2014-06-02 US US14/293,459 patent/US20140271735A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2316473A1 (en)	2011-05-04
ES2436152T3 (es)	2013-12-27
IL173002A0 (en)	2006-06-11
TWI343816B (en)	2011-06-21
WO2005014031A1 (en)	2005-02-17
MXPA06000807A (es)	2006-08-23
CA2532565A1 (en)	2005-02-17
PL2316473T3 (pl)	2014-05-30
IL173002A (en)	2013-09-30
US20060194722A1 (en)	2006-08-31
ZA200600373B (en)	2007-01-31
CA2532565C (en)	2012-05-08
AU2008202879A1 (en)	2008-07-24
NO330867B1 (no)	2011-08-01
NZ544645A (en)	2009-04-30
BRPI0412265A (pt)	2006-09-05
RU2006105479A (ru)	2007-09-10
US20100278881A1 (en)	2010-11-04
KR20060034298A (ko)	2006-04-21
JP2006528152A (ja)	2006-12-14
US8765675B2 (en)	2014-07-01
EP1651249B1 (en)	2012-09-12
AU2008202879B2 (en)	2012-05-24
PT2316473E (pt)	2013-09-20
CN1856321B (zh)	2012-10-03
ES2398237T3 (es)	2013-03-14
AU2004262906B2 (en)	2008-04-03
KR101070036B1 (ko)	2011-10-04
JP2011121987A (ja)	2011-06-23
HK1089935A1 (en)	2006-12-15
CN1856321A (zh)	2006-11-01
RU2368390C2 (ru)	2009-09-27
MA27929A1 (fr)	2006-06-01
PT1651249E (pt)	2012-12-21
TNSN06022A1 (en)	2007-10-03
EP2316473B1 (en)	2013-08-21
TW200518769A (en)	2005-06-16
US20140271735A1 (en)	2014-09-18
US7749954B2 (en)	2010-07-06
EP1651249A1 (en)	2006-05-03
IL227988A0 (en)	2013-09-30
NO20060890L (no)	2006-04-24
IS8316A (is)	2006-02-21
IL227988A (en)	2016-10-31
JP4716987B2 (ja)	2011-07-06
AU2004262906A1 (en)	2005-02-17
HK1152229A1 (en)	2012-02-24

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