PL167761B1 - Sposób wytwarzania nowych indenoindoll PL PL PL PL PL - Google Patents

Sposób wytwarzania nowych indenoindoll PL PL PL PL PL

Info

Publication number: PL167761B1
Authority: PL; Poland
Prior art keywords: indole; cis; preparation; tetrahydro; dihydro
Prior art date: 1989-06-22

Application number

PL90285752A

Other languages

English (en)

Polish (pl)

Other versions

PL285752A1 (en

Inventor

Malcolm Sainsbury

Howard G Shertzer

Original Assignee

Univ Bath

Univ Cincinnati

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-22

Filing date

1990-06-20

Publication date

1995-10-31

1990-06-20 Application filed by Univ Bath, Univ Cincinnati filed Critical Univ Bath

1991-03-11 Publication of PL285752A1 publication Critical patent/PL285752A1/xx

1995-10-31 Publication of PL167761B1 publication Critical patent/PL167761B1/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

PL90285752A 1989-06-22 1990-06-20 Sposób wytwarzania nowych indenoindoll PL PL PL PL PL PL167761B1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8902274A SE8902274D0 (sv)	1989-06-22	1989-06-22	Indenoidole compounds ii

Publications (2)

Publication Number	Publication Date
PL285752A1 PL285752A1 (en)	1991-03-11
PL167761B1 true PL167761B1 (pl)	1995-10-31

Family

ID=20376370

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL90285752A PL167761B1 (pl)	1989-06-22	1990-06-20	Sposób wytwarzania nowych indenoindoll PL PL PL PL PL

Country Status (34)

Country	Link
EP (1)	EP0409410B1 (de)
JP (1)	JP3064411B2 (de)
KR (1)	KR920702679A (de)
CN (1)	CN1033029C (de)
AT (1)	ATE135688T1 (de)
BG (1)	BG60317B2 (de)
CA (1)	CA2060897A1 (de)
DD (1)	DD297960A5 (de)
DE (1)	DE69025998T2 (de)
DK (1)	DK0409410T3 (de)
DZ (1)	DZ1428A1 (de)
ES (1)	ES2084660T3 (de)
FI (1)	FI100800B (de)
GR (1)	GR3019779T3 (de)
HR (1)	HRP920903B1 (de)
HU (1)	HUT59097A (de)
IE (1)	IE74682B1 (de)
IL (1)	IL94830A (de)
IS (1)	IS3590A7 (de)
LT (1)	LT3675B (de)
LV (1)	LV10253B (de)
MX (1)	MX21244A (de)
MY (1)	MY107311A (de)
NO (1)	NO177932C (de)
NZ (1)	NZ234175A (de)
PL (1)	PL167761B1 (de)
PT (1)	PT94468B (de)
RO (1)	RO111573B1 (de)
RU (1)	RU2104270C1 (de)
SE (1)	SE8902274D0 (de)
SI (1)	SI9011223B (de)
WO (1)	WO1990015799A1 (de)
YU (1)	YU122390A (de)
ZA (1)	ZA904827B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ65393A3 (en) *	1990-10-16	1994-02-16	Univ Bath	Indenoindole derivative, process of its preparation and pharmaceutical preparation in which said derivative is comprised
JPH0656669A (ja) *	1992-06-11	1994-03-01	Asahi Breweries Ltd	活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) *	1993-07-16	1993-07-16	Ab Astra	Use of indenoindole compounds
CA2128283A1 (fr) *	1993-07-20	1995-01-21	Paul Caubere	(thia)cycloalkyl¬b\|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6288099B1 (en)	1998-12-04	2001-09-11	American Home Products Corporation	Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
EP1135393A2 (de) *	1998-12-04	2001-09-26	American Home Products Corporation	Substituierte benzofuranindole und indenoindole als kalium kanalaktivatoren
FR2826009B1 (fr) *	2001-06-13	2003-08-15	Servier Lab	Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2008105071A (ru)	2005-07-14	2009-08-20	Айрм Ллк (Bm)	Соединения и композиции в качестве миметиков tro
DE102006047231B4 (de) *	2006-10-04	2009-02-12	Hemmerling, Hans-Jörg, Dr.	Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
JP5906309B2 (ja) *	2011-06-16	2016-04-20	コーリアリサーチインスティテュートオブケミカルテクノロジー	インダノン誘導体、その薬学的に許容される塩又は光学異性体、その調製方法及びそれを活性成分として含有するウイルス疾患の予防又は治療用の医薬組成物
US9790197B2 (en)	2012-12-14	2017-10-17	Katholieke Universiteit Leuven K.U. Leuven R & D	Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient
KR20230024887A (ko)	2020-04-20	2023-02-21	노파르티스 아게	항바이러스성 1,3-디-옥소-인덴 화합물
US12286423B2 (en)	2020-04-20	2025-04-29	Novartis Ag	Antiviral 1,3-di-oxo-indene compounds

1989
- 1989-06-22 SE SE8902274A patent/SE8902274D0/xx unknown
1990
- 1990-06-13 IS IS3590A patent/IS3590A7/is unknown
- 1990-06-20 RU SU5010937A patent/RU2104270C1/ru active
- 1990-06-20 DK DK90306718.9T patent/DK0409410T3/da active
- 1990-06-20 HU HU904825A patent/HUT59097A/hu unknown
- 1990-06-20 CA CA002060897A patent/CA2060897A1/en not_active Abandoned
- 1990-06-20 MX MX21244A patent/MX21244A/es unknown
- 1990-06-20 RO RO149127A patent/RO111573B1/ro unknown
- 1990-06-20 DE DE69025998T patent/DE69025998T2/de not_active Expired - Fee Related
- 1990-06-20 IE IE224790A patent/IE74682B1/en not_active IP Right Cessation
- 1990-06-20 DZ DZ900114A patent/DZ1428A1/fr active
- 1990-06-20 PL PL90285752A patent/PL167761B1/pl unknown
- 1990-06-20 WO PCT/GB1990/000949 patent/WO1990015799A1/en not_active Ceased
- 1990-06-20 JP JP2508940A patent/JP3064411B2/ja not_active Expired - Fee Related
- 1990-06-20 AT AT90306718T patent/ATE135688T1/de active
- 1990-06-20 ES ES90306718T patent/ES2084660T3/es not_active Expired - Lifetime
- 1990-06-20 EP EP90306718A patent/EP0409410B1/de not_active Expired - Lifetime
- 1990-06-21 IL IL9483090A patent/IL94830A/en not_active IP Right Cessation
- 1990-06-21 NZ NZ234175A patent/NZ234175A/xx unknown
- 1990-06-21 MY MYPI90001050A patent/MY107311A/en unknown
- 1990-06-21 DD DD90341939A patent/DD297960A5/de not_active IP Right Cessation
- 1990-06-21 ZA ZA904827A patent/ZA904827B/xx unknown
- 1990-06-22 SI SI9011223A patent/SI9011223B/sl unknown
- 1990-06-22 PT PT94468A patent/PT94468B/pt not_active IP Right Cessation
- 1990-06-22 CN CN90104933A patent/CN1033029C/zh not_active Expired - Fee Related
- 1990-06-22 YU YU122390A patent/YU122390A/sh unknown
1991
- 1991-12-19 FI FI915999A patent/FI100800B/fi active
- 1991-12-20 NO NO915049A patent/NO177932C/no unknown
- 1991-12-20 BG BG095667A patent/BG60317B2/bg unknown
- 1991-12-23 KR KR1019910701951A patent/KR920702679A/ko not_active Ceased
1992
- 1992-10-02 HR HRP-1223/90A patent/HRP920903B1/xx not_active IP Right Cessation
1993
- 1993-06-14 LV LVP-93-568A patent/LV10253B/xx unknown
- 1993-08-30 LT LTIP912A patent/LT3675B/lt not_active IP Right Cessation
1996
- 1996-04-29 GR GR960401159T patent/GR3019779T3/el unknown

Also Published As

Publication number	Publication date
SI9011223B (sl)	1998-08-31
IE902247L (en)	1990-12-22
LT3675B (en)	1996-01-25
HU904825D0 (en)	1992-03-30
SI9011223A (en)	1997-10-31
CN1051554A (zh)	1991-05-22
MY107311A (en)	1995-11-30
DZ1428A1 (fr)	2004-09-13
LTIP912A (en)	1995-03-27
EP0409410B1 (de)	1996-03-20
JP3064411B2 (ja)	2000-07-12
RO111573B1 (ro)	1996-11-29
ATE135688T1 (de)	1996-04-15
HRP920903A2 (hr)	1994-04-30
DD297960A5 (de)	1992-01-30
KR920702679A (ko)	1992-10-06
NZ234175A (en)	1992-12-23
FI100800B (fi)	1998-02-27
NO177932B (no)	1995-09-11
IE902247A1 (en)	1991-01-16
DE69025998D1 (de)	1996-04-25
MX21244A (es)	1994-03-31
FI915999A0 (fi)	1991-12-19
LV10253B (en)	1995-04-20
IL94830A (en)	1996-07-23
CN1033029C (zh)	1996-10-16
YU122390A (sh)	1992-09-07
AU5836990A (en)	1991-01-08
LV10253A (lv)	1994-10-20
AU644084B2 (en)	1993-12-02
HRP920903B1 (en)	1998-06-30
IS3590A7 (is)	1990-12-23
PL285752A1 (en)	1991-03-11
GR3019779T3 (en)	1996-07-31
RU2104270C1 (ru)	1998-02-10
NO915049D0 (no)	1991-12-20
IE74682B1 (en)	1997-07-30
JPH04505923A (ja)	1992-10-15
ZA904827B (en)	1991-04-24
WO1990015799A1 (en)	1990-12-27
HUT59097A (en)	1992-04-28
IL94830A0 (en)	1991-04-15
NO177932C (no)	1995-12-20
ES2084660T3 (es)	1996-05-16
CA2060897A1 (en)	1990-12-23
BG60317B2 (bg)	1994-07-25
PT94468B (pt)	1997-12-31
EP0409410A1 (de)	1991-01-23
DE69025998T2 (de)	1996-08-08
DK0409410T3 (da)	1996-04-29
SE8902274D0 (sv)	1989-06-22
NO915049L (no)	1992-02-21
PT94468A (pt)	1991-02-08

Publication	Publication Date	Title
PL167761B1 (pl)	1995-10-31	Sposób wytwarzania nowych indenoindoll PL PL PL PL PL
CS171392A3 (en)	1992-12-16	/(arylalkylpiperidin-4-yl)methyl/-2a,3,4,5-tetrahydro-1-(2h)-acetnaphthylen-1-ones and relating compounds, process of their preparation and their use
US5185360A (en)	1993-02-09	Dihydroindenoindole compounds and methods for using the same
AP339A (en)	1994-05-02	Indenoindoles compounds.
US5516788A (en)	1996-05-14	Tetrahydroindenoindole compounds useful in the treatment of conditions associated with free radical formation
IE902290A1 (en)	1991-01-16	(1,2,3,4-Tetrahydro-9-acridimino)cyclohexane carboxylic acid and related compounds, a process for their preparation and their use as medicaments
WO2006020070A2 (en)	2006-02-23	Indanylamino uracils and their use as antioxidants and neuroprotectants
FR2478094A1 (fr)	1981-09-18	Derives de cinnamylmoranoline a substitution ammonio, a activite d'inhibition de l'augmentation de niveau de sucre dans le sang
CN112608326B (zh)	2021-10-01	呋喃并[2,3-b]喹啉-3,4（2H,9H)-二酮衍生物、其制备方法及应用
AU644084C (en)	1995-01-05	Indenoindole compounds II
CN112608327A (zh)	2021-04-06	呋喃并喹啉衍生物、其制备方法及应用
CH594667A5 (en)	1978-01-13	Hexahydro-2H-pyrazolo(4,3-C) pyridine derivs