PL1697411T3 - Sposób oczyszczania interferonu beta - Google Patents

Sposób oczyszczania interferonu beta

Info

Publication number
PL1697411T3
PL1697411T3 PL04808310T PL04808310T PL1697411T3 PL 1697411 T3 PL1697411 T3 PL 1697411T3 PL 04808310 T PL04808310 T PL 04808310T PL 04808310 T PL04808310 T PL 04808310T PL 1697411 T3 PL1697411 T3 PL 1697411T3
Authority
PL
Poland
Prior art keywords
interferon beta
buffer solution
washing
propylene glycol
affinity chromatography
Prior art date
Application number
PL04808310T
Other languages
English (en)
Inventor
Ji-Sook Park
Jong-Sang Chung
Min-Ji Baek
Jee-Won Ahn
Ki-Wan Kim
Hyung-Ki Park
Dong-Eok Lee
Myung-Suk Oh
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of PL1697411T3 publication Critical patent/PL1697411T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL04808310T 2003-12-04 2004-12-04 Sposób oczyszczania interferonu beta PL1697411T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2003-0087552A KR100524871B1 (ko) 2003-12-04 2003-12-04 인터페론 베타의 정제방법
EP04808310A EP1697411B1 (en) 2003-12-04 2004-12-04 Process for purifying interferon beta
PCT/KR2004/003179 WO2005054288A1 (en) 2003-12-04 2004-12-04 Process for purifying interferon beta

Publications (1)

Publication Number Publication Date
PL1697411T3 true PL1697411T3 (pl) 2011-12-30

Family

ID=36647277

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04808310T PL1697411T3 (pl) 2003-12-04 2004-12-04 Sposób oczyszczania interferonu beta

Country Status (14)

Country Link
US (1) US7780960B2 (pl)
EP (1) EP1697411B1 (pl)
JP (1) JP2007530447A (pl)
KR (1) KR100524871B1 (pl)
CN (1) CN100462370C (pl)
AT (1) ATE521712T1 (pl)
AU (1) AU2004295265B2 (pl)
BR (1) BRPI0417220A (pl)
CA (1) CA2548160C (pl)
ES (1) ES2369911T3 (pl)
MX (1) MXPA06006357A (pl)
PL (1) PL1697411T3 (pl)
RU (1) RU2346003C2 (pl)
WO (1) WO2005054288A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007022799A1 (en) * 2005-08-26 2007-03-01 Ares Trading S.A. Process for the preparation of glycosylated interferon beta
KR100848600B1 (ko) * 2007-02-28 2008-07-28 인하대학교 산학협력단 완충용액을 이용한 재조합 단백질 대량생산 방법
RU2392282C1 (ru) * 2008-10-06 2010-06-20 Учреждение Российской академии наук Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН СПОСОБ ОЧИСТКИ РЕКОМБИНАНТНОГО ИНТЕРФЕРОНА β-1b
CN114573679B (zh) * 2022-03-29 2024-10-11 深圳科兴药业有限公司 分离重组人干扰素α1b异构体的纯化方法
CN114814000B (zh) * 2022-03-30 2024-07-23 深圳科兴药业有限公司 重组人干扰素的含量检测方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5564799A (en) 1978-11-07 1980-05-15 Toray Ind Inc Multi-stage concentration and purification of interferon originated from human fibroblast
US4289689A (en) * 1980-03-14 1981-09-15 Hoffmann-La Roche Inc. Preparation of homogeneous human fibroblast interferon
US4278661A (en) 1979-10-12 1981-07-14 E. I. Du Pont De Nemours And Company Purification of interferon
NL7907791A (nl) 1979-10-23 1981-04-27 Stichting Rega V Z W Werkwijze voor het zuiveren van interferon.
JPS58201794A (ja) 1982-05-17 1983-11-24 Toray Ind Inc ヒトインターフェロンβの濃縮精製法
US4966843A (en) 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
US4483849A (en) * 1983-01-07 1984-11-20 Carter William A Stabilization and purification of interferon with propylene glycol, resulting in a non-toxic product
US4658017A (en) 1984-02-14 1987-04-14 Health Research, Inc. (Roswell Park Division) Method for the large scale purification of human fibroblast interferon
US4808523A (en) * 1984-11-07 1989-02-28 Yeda Research And Development Co., Ltd. Constitutive production of human IFN-β1 by mammalian cells transformed by the IFN-β1 gene fused to an SV40 early promoter
FR2617763B1 (fr) 1987-07-07 1989-12-01 Essilor Int Procede de fabrication de lentille de contact en un polymere proteique naturel, par moulage avant reticulation
IT1222427B (it) 1987-07-31 1990-09-05 Sclavo Spa Procedimento per la purificazione di interferone
DE4128319A1 (de) * 1991-08-27 1993-03-04 Bioferon Biochem Substanz Neues rekombinantes human-ifn-beta, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen
EP0551535A1 (en) * 1992-01-13 1993-07-21 SCLAVO S.p.A. Process for the purification of recombinant human beta interferon, beta interferon thus purified, and pharmaceutical compositions which contain them
US7144574B2 (en) 1999-08-27 2006-12-05 Maxygen Aps Interferon β variants and conjugates

Also Published As

Publication number Publication date
AU2004295265A1 (en) 2005-06-16
EP1697411A1 (en) 2006-09-06
KR100524871B1 (ko) 2005-10-31
CN1902225A (zh) 2007-01-24
US20070093649A1 (en) 2007-04-26
MXPA06006357A (es) 2006-08-23
CN100462370C (zh) 2009-02-18
EP1697411B1 (en) 2011-08-24
ES2369911T3 (es) 2011-12-09
JP2007530447A (ja) 2007-11-01
EP1697411A4 (en) 2008-08-27
AU2004295265B2 (en) 2009-01-08
ATE521712T1 (de) 2011-09-15
RU2346003C2 (ru) 2009-02-10
KR20050054209A (ko) 2005-06-10
CA2548160C (en) 2011-06-07
BRPI0417220A (pt) 2007-02-21
US7780960B2 (en) 2010-08-24
WO2005054288A1 (en) 2005-06-16
CA2548160A1 (en) 2005-06-16
RU2006123539A (ru) 2008-01-10

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