PL1694703T3 - Sposób oczyszczania interferonu beta - Google Patents

Sposób oczyszczania interferonu beta

Info

Publication number: PL1694703T3
Authority: PL; Poland
Prior art keywords: interferon beta; buffer solution; washing; propylene glycol; affinity chromatography
Prior art date: 2003-12-04

Application number

PL04808311T

Other languages

English (en)

Inventor

Ji-Sook Park

Jong-Sang Chung

Min-Ji Baek

Jee-Won Ahn

Ki-Wan Kim

Hyung-Ki Park

Dong-Eok Lee

Myung-Suk Oh

Original Assignee

Cj Cheiljedang Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-04

Filing date

2004-12-04

Publication date

2011-12-30

2004-12-04 Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp

2011-12-30 Publication of PL1694703T3 publication Critical patent/PL1694703T3/pl

Links

102000003996 Interferon-beta Human genes 0.000 title abstract 2
108090000467 Interferon-beta Proteins 0.000 title abstract 2
229960001388 interferon-beta Drugs 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 9
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
101001054334 Homo sapiens Interferon beta Proteins 0.000 abstract 3
238000001042 affinity chromatography Methods 0.000 abstract 3
239000000243 solution Substances 0.000 abstract 3
239000011780 sodium chloride Substances 0.000 abstract 2
239000011534 wash buffer Substances 0.000 abstract 2
238000005406 washing Methods 0.000 abstract 2
239000007853 buffer solution Substances 0.000 abstract 1
238000005277 cation exchange chromatography Methods 0.000 abstract 1
239000006167 equilibration buffer Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL04808311T 2003-12-04 2004-12-04 Sposób oczyszczania interferonu beta PL1694703T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
KR10-2003-0087553A KR100524872B1 (ko)	2003-12-04	2003-12-04	인터페론 베타의 정제방법
EP04808311A EP1694703B1 (en)	2003-12-04	2004-12-04	Process for purifying interferon beta
PCT/KR2004/003180 WO2005054289A1 (en)	2003-12-04	2004-12-04	Process for purifying interferon beta

Publications (1)

Publication Number	Publication Date
PL1694703T3 true PL1694703T3 (pl)	2011-12-30

Family

ID=36647278

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL04808311T PL1694703T3 (pl)	2003-12-04	2004-12-04	Sposób oczyszczania interferonu beta

Country Status (14)

Country	Link
US (1)	US7901670B2 (pl)
EP (1)	EP1694703B1 (pl)
JP (1)	JP2007530448A (pl)
KR (1)	KR100524872B1 (pl)
CN (1)	CN1902224B (pl)
AT (1)	ATE522617T1 (pl)
AU (1)	AU2004295266B2 (pl)
BR (1)	BRPI0417252A (pl)
CA (1)	CA2548165C (pl)
ES (1)	ES2370019T3 (pl)
MX (1)	MXPA06006356A (pl)
PL (1)	PL1694703T3 (pl)
RU (1)	RU2346002C2 (pl)
WO (1)	WO2005054289A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG155183A1 (en) *	2005-08-26	2009-09-30	Ares Trading Sa	Process for the preparation of glycosylated interferon beta
DE102007050165B4 (de) *	2007-10-19	2010-06-17	Stiftung Tierärztliche Hochschule Hannover	Stabilisierte Lösung, Verfahren zu deren Herstellung sowie deren Verwendung und Arzneimittel in Form einer stabilisierten Lösung
KR101113495B1 (ko) *	2008-01-23	2012-02-29	한미홀딩스 주식회사	인간 인터페론 베타의 정제방법
RU2392282C1 (ru) *	2008-10-06	2010-06-20	Учреждение Российской академии наук Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН	СПОСОБ ОЧИСТКИ РЕКОМБИНАНТНОГО ИНТЕРФЕРОНА β-1b
EP2542574B1 (en) *	2010-03-04	2017-08-09	Pfenex Inc.	Method for producing soluble recombinant interferon protein without denaturing
CN102219848B (zh) *	2011-05-25	2014-01-22	浙江海正药业股份有限公司	重组人干扰素β-1a的纯化方法
DK2771022T3 (da)	2011-10-11	2020-09-28	Viela Bio Inc	Cd40l-specifikke tn3-afledte skeletter (scaffolds) og fremgangsmåder til anvendelse deraf
CN107428817B (zh)	2015-03-12	2022-07-12	免疫医疗有限责任公司	纯化白蛋白融合蛋白的方法
EA027609B9 (ru) *	2015-04-29	2017-11-30	Тютор С.А.С.И.Ф.И.А.	Способ получения интерферона бета-1альфа и фармацевтическая композиция, содержащая интерферон бета-1альфа

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5564799A (en)	1978-11-07	1980-05-15	Toray Ind Inc	Multi-stage concentration and purification of interferon originated from human fibroblast
US4289689A (en)	1980-03-14	1981-09-15	Hoffmann-La Roche Inc.	Preparation of homogeneous human fibroblast interferon
US4278661A (en) *	1979-10-12	1981-07-14	E. I. Du Pont De Nemours And Company	Purification of interferon
NL7907791A (nl)	1979-10-23	1981-04-27	Stichting Rega V Z W	Werkwijze voor het zuiveren van interferon.
JPS58201794A (ja)	1982-05-17	1983-11-24	Toray Ind Inc	ヒトインターフェロンβの濃縮精製法
US4966843A (en)	1982-11-01	1990-10-30	Cetus Corporation	Expression of interferon genes in Chinese hamster ovary cells
US4483849A (en) *	1983-01-07	1984-11-20	Carter William A	Stabilization and purification of interferon with propylene glycol, resulting in a non-toxic product
US4658017A (en) *	1984-02-14	1987-04-14	Health Research, Inc. (Roswell Park Division)	Method for the large scale purification of human fibroblast interferon
US4808523A (en) *	1984-11-07	1989-02-28	Yeda Research And Development Co., Ltd.	Constitutive production of human IFN-β1 by mammalian cells transformed by the IFN-β1 gene fused to an SV40 early promoter
IT1222427B (it)	1987-07-31	1990-09-05	Sclavo Spa	Procedimento per la purificazione di interferone
IT1240612B (it) *	1990-03-16	1993-12-17	Sclavo Spa	Procedimento di purificazione del b-interferone umano ricombinante
EP0551535A1 (en)	1992-01-13	1993-07-21	SCLAVO S.p.A.	Process for the purification of recombinant human beta interferon, beta interferon thus purified, and pharmaceutical compositions which contain them
US7144574B2 (en)	1999-08-27	2006-12-05	Maxygen Aps	Interferon β variants and conjugates

2003
- 2003-12-04 KR KR10-2003-0087553A patent/KR100524872B1/ko not_active Expired - Fee Related
2004
- 2004-12-04 JP JP2006542506A patent/JP2007530448A/ja active Pending
- 2004-12-04 CA CA2548165A patent/CA2548165C/en not_active Expired - Fee Related
- 2004-12-04 US US10/581,597 patent/US7901670B2/en not_active Expired - Fee Related
- 2004-12-04 EP EP04808311A patent/EP1694703B1/en not_active Expired - Lifetime
- 2004-12-04 CN CN2004800397237A patent/CN1902224B/zh not_active Expired - Fee Related
- 2004-12-04 RU RU2006123543/13A patent/RU2346002C2/ru not_active IP Right Cessation
- 2004-12-04 PL PL04808311T patent/PL1694703T3/pl unknown
- 2004-12-04 AU AU2004295266A patent/AU2004295266B2/en not_active Ceased
- 2004-12-04 ES ES04808311T patent/ES2370019T3/es not_active Expired - Lifetime
- 2004-12-04 WO PCT/KR2004/003180 patent/WO2005054289A1/en not_active Ceased
- 2004-12-04 BR BRPI0417252-3A patent/BRPI0417252A/pt not_active IP Right Cessation
- 2004-12-04 AT AT04808311T patent/ATE522617T1/de not_active IP Right Cessation
- 2004-12-04 MX MXPA06006356A patent/MXPA06006356A/es active IP Right Grant

Also Published As

Publication number	Publication date
BRPI0417252A (pt)	2007-03-06
EP1694703A4 (en)	2008-08-27
AU2004295266A1 (en)	2005-06-16
CA2548165A1 (en)	2005-06-16
KR100524872B1 (ko)	2005-11-01
CA2548165C (en)	2011-10-04
EP1694703B1 (en)	2011-08-31
US20070123697A1 (en)	2007-05-31
ES2370019T3 (es)	2011-12-12
US7901670B2 (en)	2011-03-08
KR20050054210A (ko)	2005-06-10
JP2007530448A (ja)	2007-11-01
AU2004295266B2 (en)	2009-01-08
RU2006123543A (ru)	2008-01-10
CN1902224B (zh)	2012-05-30
ATE522617T1 (de)	2011-09-15
RU2346002C2 (ru)	2009-02-10
CN1902224A (zh)	2007-01-24
WO2005054289A1 (en)	2005-06-16
MXPA06006356A (es)	2006-08-23
EP1694703A1 (en)	2006-08-30

Publication	Publication Date	Title
AU1577795A (en)	1995-08-21	Endotoxin reduction or removal process
UA99263C2 (ru)	2012-08-10	СПОСОБ ОЧИСТКИ Fc-СЛИТОГО БЕЛКА
PL1694703T3 (pl)	2011-12-30	Sposób oczyszczania interferonu beta
TW283710B (pl)	1996-08-21
NZ509135A (en)	2002-10-25	A third generation intravenous immunoglobulin G (IVIG) purified using column chromatographic ion exchange methods
SG162806A1 (en)	2010-07-29	Methods of purifying anti a beta antibodies
YU5502A (sh)	2005-06-10	Amidi karbonskih kiselina, lekovi koji sadrže ova jedinjenja, njihova upotreba i proizvodnja
GB0216001D0 (en)	2002-08-21	Process and composition
KR930702381A (ko)	1993-09-08	혈청 알부민의 정제방법
KR840003422A (ko)	1984-09-08	균질한 인체 면역 인터페론의 제조방법
PL1697411T3 (pl)	2011-12-30	Sposób oczyszczania interferonu beta
HU9301038D0 (en)	1993-06-28	Method for producing virus-safe vii factor of high purity
SE8005498L (sv)	1981-02-01	Homogent fibroblastinterferon och framstellning derav
IL172868A0 (en)	2006-06-11	Process for preparing an alpha-1-antitrypsin solution
CA2306820A1 (en)	1999-09-16	Improved methods for producing factor viii proteins
AU2003262258A8 (en)	2004-03-29	Method of purifying protein and glucose dehydrogenase
BRPI0418992A (pt)	2007-12-11	processo para a purificação de hormÈnio do crescimento humano
IL182830A0 (en)	2007-08-19	Purification of recombinant human factor xiii
EP0446850A2 (en)	1991-09-18	Process for purifying recombinant human beta-interferon
Atakuziev et al.	1991	Phospholipase A2 from the venom of the spider Eresus niger
KR910015699A (ko)	1991-09-30	리포코틴의 정제방법
JPH07113022B2 (ja)	1995-12-06	ピロロキノリンキノンの精製方法
KR970006501A (ko)	1997-02-21	재조합 효모로부터 과립구-콜로니자극인자(g-csf)를 정제하는 방법
DE69935724D1 (en)	2007-05-16	L-acetylcarnitine als antitumormittel
NO915032L (no)	1992-02-07	Interferonrenseprosess