PL1698640T5 - Sposób stabilizacji przeciwciała i stabilizowany preparat przeciwciała w postaci roztworu - Google Patents

Sposób stabilizacji przeciwciała i stabilizowany preparat przeciwciała w postaci roztworu

Info

Publication number
PL1698640T5
PL1698640T5 PL04773700T PL04773700T PL1698640T5 PL 1698640 T5 PL1698640 T5 PL 1698640T5 PL 04773700 T PL04773700 T PL 04773700T PL 04773700 T PL04773700 T PL 04773700T PL 1698640 T5 PL1698640 T5 PL 1698640T5
Authority
PL
Poland
Prior art keywords
antibody
stabilizing
stabilized solution
type
preparation
Prior art date
Application number
PL04773700T
Other languages
English (en)
Other versions
PL1698640T3 (pl
Inventor
Yuji Ueno
Takashi Kayashita
Atsushi Ishihara
Masashi Nakakura
Kyoko Yamauchi
Original Assignee
Kyowa Hakko Kirin Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34419308&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1698640(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kirin Co., Ltd. filed Critical Kyowa Hakko Kirin Co., Ltd.
Publication of PL1698640T3 publication Critical patent/PL1698640T3/pl
Publication of PL1698640T5 publication Critical patent/PL1698640T5/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
PL04773700T 2003-10-01 2004-10-01 Sposób stabilizacji przeciwciała i stabilizowany preparat przeciwciała w postaci roztworu PL1698640T5 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003343645 2003-10-01
EP04773700.2A EP1698640B2 (en) 2003-10-01 2004-10-01 Method of stabilizing antibody and stabilized solution-type antibody preparation
PCT/JP2004/014903 WO2005033143A1 (ja) 2003-10-01 2004-10-01 抗体の安定化方法及び安定化された溶液状抗体製剤

Publications (2)

Publication Number Publication Date
PL1698640T3 PL1698640T3 (pl) 2016-05-31
PL1698640T5 true PL1698640T5 (pl) 2019-12-31

Family

ID=34419308

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04773700T PL1698640T5 (pl) 2003-10-01 2004-10-01 Sposób stabilizacji przeciwciała i stabilizowany preparat przeciwciała w postaci roztworu

Country Status (15)

Country Link
US (3) US8496930B2 (pl)
EP (2) EP3006463A1 (pl)
JP (1) JP4219932B2 (pl)
KR (1) KR100911091B1 (pl)
CN (1) CN100522998C (pl)
AU (1) AU2004277466C1 (pl)
CA (1) CA2540848C (pl)
CY (1) CY1117215T1 (pl)
DK (1) DK1698640T4 (pl)
ES (1) ES2562912T5 (pl)
HU (1) HUE026793T2 (pl)
PL (1) PL1698640T5 (pl)
PT (1) PT1698640E (pl)
SI (1) SI1698640T2 (pl)
WO (1) WO2005033143A1 (pl)

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US7776331B1 (en) * 2007-01-16 2010-08-17 Abbott Laboratories Methods of treating plaque psoriasis
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US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
SG10201604258YA (en) * 2007-11-30 2016-07-28 Abbvie Biotechnology Ltd Anti-tnf antibody formulations
TWI461210B (zh) * 2008-03-18 2014-11-21 Abbvie Inc 治療牛皮癬的方法
AU2009319856A1 (en) * 2008-11-28 2010-06-03 Abbvie Inc. Stable antibody compositions and methods for stabilizing same
CA2760185A1 (en) * 2009-05-04 2010-11-11 Abbott Biotechnology Ltd. Stable high protein concentration formulations of human anti-tnf-alpha antibodies
WO2010139752A2 (en) 2009-06-04 2010-12-09 Alk Ag Stabilised composition comprising at least one adrenergic compound
MX2012003138A (es) * 2009-09-14 2012-07-04 Abbott Lab Y Abbott Gmbh & Co Kg Metodos para tratar la psoriasis.
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KR20190047135A (ko) 2010-03-01 2019-05-07 바이엘 헬스케어 엘엘씨 조직 인자 경로 억제제 (ｔｆｐｉ)에 대한 최적화된 모노클로날 항체
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ES2601202T3 (es) 2010-11-11 2017-02-14 Abbvie Biotechnology Ltd Formulaciones liquidas de anticuerpos anti-TNT-alfa de alta concentración
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
US8883979B2 (en) 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
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US9592297B2 (en) 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
JP6527697B2 (ja) 2013-01-28 2019-06-05 国立大学法人 熊本大学 タンパク質を安定化させたゲル状製剤
MX380569B (es) * 2013-07-19 2025-03-12 Hexal Ag Métodos y formulaciones que permiten la modulación de respuestas inmunitarias relacionadas con la administración de un fármaco biofarmacéutico.
CN103772505B (zh) * 2013-12-18 2014-10-15 长春博迅生物技术有限责任公司 一种抗体试剂保存液
US10513553B2 (en) 2015-11-13 2019-12-24 Visterra, Inc. Compositions and methods for treating and preventing influenza
EP3419663A1 (en) * 2016-02-24 2019-01-02 Visterra, Inc. Formulations of antibody molecules to influenza virus
WO2017170626A1 (ja) * 2016-03-30 2017-10-05 千寿製薬株式会社 水性液剤
CN120241997A (zh) 2019-02-18 2025-07-04 伊莱利利公司 治疗性抗体制剂
EP3930757A1 (en) 2019-03-01 2022-01-05 President And Fellows Of Harvard College Methods and compositions for protein delivery
JP2022521819A (ja) 2019-03-25 2022-04-12 ビステラ， インコーポレイテッド インフルエンザを処置および予防するための組成物および方法
JP2022551622A (ja) * 2019-10-11 2022-12-12 ドクター レディズ ラボラトリーズ リミテッド インテグリン抗体の安定な製剤
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Also Published As

Publication number Publication date
US9011850B2 (en) 2015-04-21
ES2562912T3 (es) 2016-03-09
US20130280248A1 (en) 2013-10-24
AU2004277466A1 (en) 2005-04-14
DK1698640T3 (en) 2016-02-15
WO2005033143A1 (ja) 2005-04-14
US8496930B2 (en) 2013-07-30
JP4219932B2 (ja) 2009-02-04
ES2562912T5 (es) 2020-02-18
EP3006463A1 (en) 2016-04-13
CA2540848A1 (en) 2005-04-14
DK1698640T4 (da) 2019-09-02
CN1856507A (zh) 2006-11-01
EP1698640A1 (en) 2006-09-06
JPWO2005033143A1 (ja) 2007-11-15
EP1698640A4 (en) 2008-09-17
KR20060089227A (ko) 2006-08-08
US20150190507A1 (en) 2015-07-09
SI1698640T1 (sl) 2016-03-31
US10172790B2 (en) 2019-01-08
EP1698640B2 (en) 2019-06-19
CY1117215T1 (el) 2017-04-05
CN100522998C (zh) 2009-08-05
AU2004277466C1 (en) 2022-06-23
PL1698640T3 (pl) 2016-05-31
EP1698640B1 (en) 2015-12-30
SI1698640T2 (sl) 2019-08-30
KR100911091B1 (ko) 2009-08-06
HK1090933A1 (en) 2007-01-05
US20070020255A1 (en) 2007-01-25
HUE026793T2 (en) 2016-07-28
AU2004277466B2 (en) 2010-04-01
PT1698640E (pt) 2016-03-31
CA2540848C (en) 2012-12-11

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