PL1756095T3 - Cyjanopirole zawierające cykliczne karbaminianowe i tiokarbaminianowe biaryle oraz sposoby ich wytwarzania - Google Patents

Cyjanopirole zawierające cykliczne karbaminianowe i tiokarbaminianowe biaryle oraz sposoby ich wytwarzania

Info

Publication number: PL1756095T3
Authority: PL; Poland
Prior art keywords: optionally substituted; same; methyl; cyanopyrrole; alkyl
Prior art date: 2004-04-27

Application number

PL05740218T

Other languages

English (en)

Inventor

Bogdan Kazimierz Wilk

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-04-27

Filing date

2005-04-25

Publication date

2008-10-31

2005-04-25 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-10-31 Publication of PL1756095T3 publication Critical patent/PL1756095T3/pl

Links

BQMPGKPTOHKYHS-UHFFFAOYSA-N 1h-pyrrole-2-carbonitrile Chemical compound N#CC1=CC=CN1 BQMPGKPTOHKYHS-UHFFFAOYSA-N 0.000 title abstract 2
-1 thiocarbamate biaryls Chemical class 0.000 title abstract 2
KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title 1
125000004122 cyclic group Chemical group 0.000 title 1
125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000004103 aminoalkyl group Chemical group 0.000 abstract 3
JDCAVWLLZCSPTB-UHFFFAOYSA-N 5-(3-acetyl-4-aminophenyl)-1-methylpyrrole-2-carbonitrile Chemical compound C1=C(N)C(C(=O)C)=CC(C=2N(C(C#N)=CC=2)C)=C1 JDCAVWLLZCSPTB-UHFFFAOYSA-N 0.000 abstract 1
AKWXTECOJTWHIU-UHFFFAOYSA-N 5-[4-amino-3-(2-hydroxypropan-2-yl)phenyl]-1-methylpyrrole-2-carbonitrile Chemical compound CN1C(C#N)=CC=C1C1=CC=C(N)C(C(C)(C)O)=C1 AKWXTECOJTWHIU-UHFFFAOYSA-N 0.000 abstract 1
125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
241000689227 Cora <basidiomycete fungus> Species 0.000 abstract 1
241000347391 Umbrina cirrosa Species 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
IVBWMGBBBAVXRJ-UHFFFAOYSA-N methyl 2-amino-5-(5-cyano-1-methylpyrrol-2-yl)benzoate Chemical compound C1=C(N)C(C(=O)OC)=CC(C=2N(C(C#N)=CC=2)C)=C1 IVBWMGBBBAVXRJ-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
150000003558 thiocarbamic acid derivatives Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL05740218T 2004-04-27 2005-04-25 Cyjanopirole zawierające cykliczne karbaminianowe i tiokarbaminianowe biaryle oraz sposoby ich wytwarzania PL1756095T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US56561604P	2004-04-27	2004-04-27
PCT/US2005/014342 WO2005105739A2 (en)	2004-04-27	2005-04-25	Cyanopyrrole containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same
EP05740218A EP1756095B1 (en)	2004-04-27	2005-04-25	Cyanopyrrole containing cyclic carbamate and thiocarbamate biaryls and methods for preparing the same

Publications (1)

Publication Number	Publication Date
PL1756095T3 true PL1756095T3 (pl)	2008-10-31

Family

ID=35242253

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL05740218T PL1756095T3 (pl)	2004-04-27	2005-04-25	Cyjanopirole zawierające cykliczne karbaminianowe i tiokarbaminianowe biaryle oraz sposoby ich wytwarzania

Country Status (14)

Country	Link
US (3)	US7582755B2 (pl)
EP (1)	EP1756095B1 (pl)
JP (2)	JP5108506B2 (pl)
CN (1)	CN1946716B (pl)
AT (1)	ATE396189T1 (pl)
AU (1)	AU2005238520B2 (pl)
BR (1)	BRPI0510278A (pl)
CA (1)	CA2562160C (pl)
DE (1)	DE602005007021D1 (pl)
DK (1)	DK1756095T3 (pl)
ES (1)	ES2306140T3 (pl)
MX (1)	MXPA06012402A (pl)
PL (1)	PL1756095T3 (pl)
WO (1)	WO2005105739A2 (pl)

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UA73119C2 (en) *	2000-04-19	2005-06-15	American Home Products Corpoir	Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
JP5108506B2 (ja)	2004-04-27	2012-12-26	ワイス・エルエルシー	シアノピロール含有環式カルバメートおよびチオカルバメートビアリール、およびこれらの製造方法
BRPI0610438A2 (pt)	2005-04-28	2012-10-23	Wyeth Corp	composição farmacêutica, cápsula, conjunto farmacêutico, e, processo para preparar uma composição
WO2006116596A2 (en) *	2005-04-28	2006-11-02	Wyeth	Micronized tanaproget and compostions containing same
US7767668B2 (en) *	2005-04-28	2010-08-03	Wyeth Llc	Micronized tanaproget, compositions, and methods of preparing the same
PE20070404A1 (es)	2005-07-29	2007-05-10	Wyeth Corp	Compuestos derivados de cianopirrol-sulfonamida como moduladores del receptor de progesterona
PE20070182A1 (es) *	2005-07-29	2007-03-06	Wyeth Corp	Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona
PE20070341A1 (es) *	2005-07-29	2007-04-13	Wyeth Corp	Derivados de pirrol como moduladores del receptor de progesterona
PE20070220A1 (es) *	2005-07-29	2007-03-19	Wyeth Corp	Proceso para la sintesis de moduladores del receptor de progesterona
US20070213526A1 (en) *	2006-03-07	2007-09-13	Wyeth	Purification of progesterone receptor modulators
US20080319204A1 (en) *	2007-06-25	2008-12-25	Wyeth	Process for the synthesis of progesterone receptor modulators
US20090170823A1 (en) *	2007-12-20	2009-07-02	Duramed Pharmaceuticals, Inc.	Dosage Regimens and Pharmaceutical Compositions and Packages for Emergency Contraception
GB0817578D0 (en) *	2008-09-25	2008-11-05	3M Innovative Properties Co	Method for treating wheel rims and composition for use therein

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US5194628A (en) *	1988-03-18	1993-03-16	Ciba-Geigy Corporation	Process for the preparation of substituted difluorobenzo-1,3-dioxoles
EP0717740A1 (de)	1993-09-10	1996-06-26	Ciba SC Holding AG	Photochrome verbindungen, verfahren und zwischenprodukte zu deren hestellung und deren verwendung
US6545108B1 (en)	1999-02-22	2003-04-08	Eastman Chemical Company	Catalysts containing N-pyrrolyl substituted nitrogen donors
WO2000050470A2 (en)	1999-02-22	2000-08-31	Eastman Chemical Company	Catalysts containing n-pyrrolyl substituted nitrogen donors
US6509334B1 (en) *	1999-05-04	2003-01-21	American Home Products Corporation	Cyclocarbamate derivatives as progesterone receptor modulators
KR100732692B1 (ko) *	1999-05-04	2007-06-27	와이어쓰	프로게스테론 수용체 조절인자인 시클로티오카르바메이트유도체
US6407101B1 (en) *	1999-05-04	2002-06-18	American Home Products Corporation	Cyanopyrroles
US6391907B1 (en) *	1999-05-04	2002-05-21	American Home Products Corporation	Indoline derivatives
MXPA01011286A (es) *	1999-05-04	2003-07-14	American Home Prod	Derivados de ciclocarbamato como moduladores de receptor de progesterona.
WO2000066560A1 (en)	1999-05-04	2000-11-09	American Home Products Corporation	Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
EP1175404A1 (en) *	1999-05-04	2002-01-30	American Home Products Corporation	Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6566372B1 (en) *	1999-08-27	2003-05-20	Ligand Pharmaceuticals Incorporated	Bicyclic androgen and progesterone receptor modulator compounds and methods
US20020065192A1 (en) *	2000-02-18	2002-05-30	Mackenzie Peter Borden	Productivity catalysts and microstructure control
UA73119C2 (en) *	2000-04-19	2005-06-15	American Home Products Corpoir	Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
US6350837B1 (en)	2000-06-09	2002-02-26	Eastman Chemical Company	Copolymerization of norbornene and functional norbornene monomers
EP1404723A2 (en)	2000-11-06	2004-04-07	Eastman Chemical Company	Olefin polymerization processes using supported catalysts
WO2002036641A2 (en)	2000-11-06	2002-05-10	Eastman Chemical Company	Improved productivity catalysts and microstructure control
AU2002218309A1 (en)	2000-11-27	2002-06-03	Ciba Specialty Chemicals Holding Inc.	Substituted 5-aryl and 5-heteroaryl-2-(2-hydroxyphenyl)-2h-benzotriazole derivatives as uv absorbers
US6387992B1 (en) *	2000-11-27	2002-05-14	Ciba Specialty Chemicals Corporation	Substituted 5-heteroaryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, a process for preparation thereof and compositions stabilized therewith
DE10111262A1 (de)	2001-03-09	2002-09-12	Studiengesellschaft Kohle Mbh	Verfahren zur Herstellung von Vinyl- Aryl- und Heteroarylessigsäuren und ihrer Devivate
JP2005194190A (ja)	2001-10-05	2005-07-21	Fumie Satou	１９−ノル−ビタミンｄ誘導体の製造法
DE10152989A1 (de)	2001-10-26	2003-05-08	Bayer Ag	Komplexe N-heterocyslischer Carbene und ihre Verwendung
AU2003223930A1 (en)	2002-06-14	2003-12-31	Novo Nordisk A/S	Pharmaceutical use of boronic acids and esters thereof
AU2003247608A1 (en) *	2002-06-25	2004-01-06	Wyeth	Use of cyclothiocarbamate derivatives in treatment of hormone-related conditions
EP1531824A4 (en) *	2002-06-25	2005-09-21	Wyeth Corp	CYCLOTHIOCARBAMATE DERIVATIVES AS PR-MODULATORS AND THEIR USE IN THE TREATMENT OF SKIN DISEASES
BRPI0510260A (pt)	2004-04-27	2007-10-23	Wyeth Corp	método para purificar um composto, e, kit farmacêutico
JP5108506B2 (ja)	2004-04-27	2012-12-26	ワイス・エルエルシー	シアノピロール含有環式カルバメートおよびチオカルバメートビアリール、およびこれらの製造方法
PA8631101A1 (es)	2004-04-27	2006-09-08	Wyeth Corp	Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos

2005
- 2005-04-25 JP JP2007510902A patent/JP5108506B2/ja not_active Expired - Fee Related
- 2005-04-25 DK DK05740218T patent/DK1756095T3/da active
- 2005-04-25 AU AU2005238520A patent/AU2005238520B2/en not_active Ceased
- 2005-04-25 EP EP05740218A patent/EP1756095B1/en not_active Expired - Lifetime
- 2005-04-25 WO PCT/US2005/014342 patent/WO2005105739A2/en not_active Ceased
- 2005-04-25 AT AT05740218T patent/ATE396189T1/de not_active IP Right Cessation
- 2005-04-25 MX MXPA06012402A patent/MXPA06012402A/es active IP Right Grant
- 2005-04-25 DE DE602005007021T patent/DE602005007021D1/de not_active Expired - Lifetime
- 2005-04-25 BR BRPI0510278-2A patent/BRPI0510278A/pt not_active IP Right Cessation
- 2005-04-25 US US11/113,795 patent/US7582755B2/en not_active Expired - Fee Related
- 2005-04-25 CN CN200580013271XA patent/CN1946716B/zh not_active Expired - Fee Related
- 2005-04-25 ES ES05740218T patent/ES2306140T3/es not_active Expired - Lifetime
- 2005-04-25 PL PL05740218T patent/PL1756095T3/pl unknown
- 2005-04-25 CA CA2562160A patent/CA2562160C/en not_active Expired - Fee Related
2009
- 2009-07-24 US US12/508,679 patent/US8003784B2/en not_active Expired - Fee Related
2011
- 2011-07-11 US US13/179,730 patent/US8129524B2/en not_active Expired - Fee Related
2012
- 2012-08-28 JP JP2012187513A patent/JP2013006853A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
DK1756095T3 (da)	2008-08-11
ATE396189T1 (de)	2008-06-15
JP5108506B2 (ja)	2012-12-26
US20090306371A1 (en)	2009-12-10
DE602005007021D1 (de)	2008-07-03
US20120016118A1 (en)	2012-01-19
ES2306140T3 (es)	2008-11-01
US8003784B2 (en)	2011-08-23
CA2562160C (en)	2013-05-28
EP1756095B1 (en)	2008-05-21
WO2005105739A2 (en)	2005-11-10
BRPI0510278A (pt)	2007-10-30
CN1946716B (zh)	2011-12-21
EP1756095A2 (en)	2007-02-28
WO2005105739A3 (en)	2006-02-16
US8129524B2 (en)	2012-03-06
CA2562160A1 (en)	2005-11-10
AU2005238520B2 (en)	2011-09-08
MXPA06012402A (es)	2007-01-17
CN1946716A (zh)	2007-04-11
US20050239779A1 (en)	2005-10-27
JP2013006853A (ja)	2013-01-10
AU2005238520A1 (en)	2005-11-10
US7582755B2 (en)	2009-09-01
JP2007534767A (ja)	2007-11-29

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